EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

calcium lactate
propanoic acid, 2-hydroxy-, calcium salt (2:1)

Supplier Sponsors

Name:calcium 2-hydroxypropanoate
CAS Number: 814-80-2Picture of molecule3D/inchi
Other(deleted CASRN):145179-24-4
ECHA EINECS - REACH Pre-Reg:212-406-7
Nikkaji Web:J2.113J
Molecular Weight:218.21890000
Formula:C6 H10 Ca O6
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:buffering agents, dough conditioners, yeast food
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1207 Calcium Lactate View - review
184.1207 L(+)-calcium lactate View - review
GRN 378 Cultured [dairy sources, sugars, wheat, malt, and fruit- and vegetable-based sources] View - notice PDF
EU SANCO Calcium lactate View - review
GRN 747 Calcium lactate View - notice PDF
JECFA Food Additive: Calcium Lactate
GSFA Codex: Calcium lactate (327)
DG SANTE Food Additives:calcium lactate
FDA Mainterm (SATF):814-80-2 ; CALCIUM LACTATE
FDA Regulation:
Subpart B--Requirements for Specific Standardized Canned Fruits
Sec. 145.145 Canned grapefruit.

Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.141 Artificially sweetened fruit jelly.

Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.161 Artificially sweetened fruit preserves and jams.

Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1207 Calcium lactate.
Physical Properties:
Appearance:white to cream crystalline powder (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 227.00 to 228.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.015000 mmHg @ 25.00 °C. (est)
Flash Point: 229.00 °F. TCC ( 109.44 °C. )
logP (o/w): -0.698 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Insoluble in:
Organoleptic Properties:
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: astringents
buffering agents
American Elements
Calcium Lactate Anhydrous 99%
Odor: characteristic
Use: Calcium Lactate Anhydrous is one of numerous organo-metallic compounds sold by American Elements under the tradename AE Organo-Metallics™ for uses requiring non-aqueous solubility such as recent solar energy and water treatment applications. Calcium Lactate Anhydrous is generally immediately available in most volumes, including bulk quantities. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
calcium lactate-gluconate (GLOCAL®)
American International Chemical, LLC.
Calcium Lactate
Anhui Haibei
Calcium Lactate
BOC Sciences
For experimental / research use only.
Calcium lactate
Foodchem International
Calcium Lactate
Global Calcium
Calcium Lactate Gluconate
Global Calcium
Calcium Lactate IP
Godavari Biorefineries
Calcium Lactate 98%
Graham Chemical
Calcium Lactate
Jost Chemical
Calcium Lactate Anhydrous USP Powder
Jungbunzlauer Suisse
Calcium Lactate Gluconate
Kraft Chemical
Calcium Lactate
Calcium Lactate Powder
Qingdao Dacon Trading
Calcium Lactate
Tianjin Talent Chemical
Calcium Lactate
Calcium Lactate Gluconate
Flavor: bland
Calcium lactate gluconate (C3H5O3)2Ca + (C6H11O7)2Ca, is a white crystalline salt made by the action of lactic acid on calcium carbonate. It is used in foods (as a baking powder) and given medicinally.Calcium lactate is often found in aged cheeses. Small crystals of it precipitate out when lactic acid is converted into a less soluble form by the bacteria active during the ripening process.
Wedor Corporation
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-dog LDLo 80 mg/kg
International Journal of Toxicology. Vol. 17(Suppl

intravenous-mouse LDLo 140 mg/kg
Journal of the American Pharmaceutical Association. Vol. 27, Pg. 484, 1938.

intravenous-rabbit LDLo 180 mg/kg
International Journal of Toxicology. Vol. 17(Suppl

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
buffering agents, dough conditioners, yeast food
Recommendation for calcium lactate usage levels up to:
 not for fragrance use.
Recommendation for calcium lactate flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Safety and efficacy of lactic acid and calcium lactate when used as technological additives for all animal species
View page or View pdf

Safety of lactic acid and calcium lactate when used as technological additives for all animal species
View page or View pdf

Safety of lactic acid and calcium lactate when used as technological additives for all animal species
View page or View pdf

EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA Substance Registry Services (TSCA):814-80-2
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :13144
National Institute of Allergy and Infectious Diseases:Data
calcium 2-hydroxypropanoate
 calcium 2-hydroxypropanoate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:814-80-2
Pubchem (cid):13144
Pubchem (sid):134977177
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
FDA Listing of Food Additive Status:View
•calcium lactate usp; powder usp, tablets usp, 325 mg (42.25 mg calcium), & 650 mg (84.5 mg calcium) •commercial prepn usually contains about 25% water, and on the anhydrous basis it is at least 98% pure. •grades: nf; fcc.
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
 calcium 2-hydroxypropanoate
 calcium 2-hydroxypropanoate (1:2)
 calcium bis(2-hydroxypropanoate)
 calcium dilactate
 calcium dilactate hydrate
 calcium lactate gluconate
 calcium lactate powder
 calcium lactate USP anhydrous
 calcium lactate-gluconate (glocal)
bis(2-hydroxypropanoate) de calcium
2-hydroxypropanoic acid calcium salt
 lactic acid calcium salt
 lactic acid calcium salt (2:1)
 propanoic acid, 2-hydroxy-, calcium salt (2:1)


PubMed:A novel low-temperature-active pectin methylesterase from Penicillium chrysogenum F46 with high efficiency in fruit firming.
PubMed:Efficient calcium lactate production by fermentation coupled with crystallization-based in situ product removal.
PubMed:Effectiveness of calcium chloride and calcium lactate on maintenance of textural and sensory qualities of fresh-cut mangos.
PubMed:Surface roughness and packaging tightness affect calcium lactate crystallization on Cheddar cheese.
PubMed:Spontaneous supersaturation of calcium D-gluconate during isothermal dissolution of calcium L-lactate in aqueous sodium D-gluconate.
PubMed:Combined vacuum impregnation and electron-beam irradiation treatment to extend the storage life of sliced white button mushrooms (Agaricus bisporus).
PubMed:Influence of calcium lactate and modified atmosphere on respiration rate, optical and mechanical properties of sliced persimmon.
PubMed:Aqueous solubility of calcium L-lactate, calcium D-gluconate, and calcium D-lactobionate: importance of complex formation for solubility increase by hydroxycarboxylate mixtures.
PubMed:Salt equivalence and temporal dominance of sensations of different sodium chloride substitutes in butter.
PubMed:Effect of storage temperature on crystal formation rate and growth rate of calcium lactate crystals on smoked Cheddar cheeses.
PubMed:Antioxidant and micronutrient-rich milk formula reduces lead poisoning and related oxidative damage in lead-exposed mice.
PubMed:Safety and efficacy of polycalcium for improving biomarkers of bone metabolism: a 4-week open-label clinical study.
PubMed:The Effect of Modified Atmosphere Packaging and Addition of Rosemary Extract, Sodium Acetate and Calcium Lactate Mixture on the Quality of Pre-cooked Hamburger Patties during Refrigerated Storage.
PubMed:Effects of feeding a single or sequence of beta-adrenergic agonists on cull cow meat quality.
PubMed:Influence of beet sugar, calcium lactate, and Staphylococcus xylosus (with nitrate reductase activity) on the chemical, microbiological, and sensorial properties of Persian uncured frankfurters.
PubMed:Using antibrowning agents to enhance quality and safety of fresh-cut avocado treated with intense light pulses.
PubMed:In situ evaluation of the erosive potential of orange juice modified by food additives.
PubMed:Feasibility of using dialysis for determining calcium ion concentration and pH in calcium-fortified soymilk at high temperature.
PubMed:In vitro evaluation of the erosive potential of orange juice modified by food additives in enamel and dentine.
PubMed:Effect of sodium gluconate on the solubility of calcium lactate.
PubMed:Effect of cassava starch coating on quality and shelf life of fresh-cut pineapple (Ananas comosus L. Merril cv "Pérola").
PubMed:Calcium lactate effect on the shelf life of osmotically dehydrated guavas.
PubMed:Implementation of acrylamide mitigation strategies on industrial production of French fries: challenges and pitfalls.
PubMed:Reduction of blood lead levels in lead-exposed mice by dietary supplements and natural antioxidants.
PubMed:Controlling the bleeding of carmine colorant in crabstick.
PubMed:Functional fermented whey-based beverage using lactic acid bacteria.
PubMed:Usefulness of calcium lactate, citrate and gluconate for calcium enrichment of dry fermented sausages.
PubMed:A comparison of needle-free and needle-injection methods and solutions for enhancement of beef longissimus lumborum muscles.
PubMed:Relative transcription of Listeria monocytogenes virulence genes in liver pâtés with varying NaCl content.
PubMed:Chemical changes that predispose smoked Cheddar cheese to calcium lactate crystallization.
PubMed:Improving the quality of fresh-cut apples, pears, and melons using natural additives.
PubMed:Thermal inactivation of Escherichia coli O157:H7 in beef treated with marination and tenderization ingredients.
PubMed:Influence of salt-to-moisture ratio on starter culture and calcium lactate crystal formation.
PubMed:Comparative study on essential oils incorporated into an alginate-based edible coating to assure the safety and quality of fresh-cut Fuji apples.
PubMed:Characterization of calcium lactate crystals on cheddar cheese by image analysis.
PubMed:Calcium taste preferences: genetic analysis and genome screen of C57BL/6J x PWK/PhJ hybrid mice.
PubMed:Effect of storage in juice with or without pulp and/or calcium lactate on the subsequent survival of Escherichia coli O157:H7 in simulated gastric fluid.
PubMed:Influence of micronutrients on rheological characteristics and bread-making quality of flour.
PubMed:Use of calcium, potassium, and sodium lactates to control germination and outgrowth of Clostridium perfringens spores during chilling of injected pork.
PubMed:Calcium supplementation in clinical practice: a review of forms, doses, and indications.
PubMed:Forty mouse strain survey of voluntary calcium intake, blood calcium, and bone mineral content.
PubMed:Inhibition of germination and outgrowth of Clostridium perfringens spores by lactic acid salts during cooling of injected turkey.
PubMed:Fortification of all-purpose wheat-flour tortillas with calcium lactate, calcium carbonate, or calcium citrate is acceptable.
PubMed:The formation of calcium lactate crystals is responsible for concentrated acid whey thickening.
PubMed:Cheese pH, protein concentration, and formation of calcium lactate crystals.
PubMed:Calcium absorption is not increased by caseinophosphopeptides.
PubMed:Nonstarter lactic acid bacteria biofilms and calcium lactate crystals in Cheddar cheese.
PubMed:Development of fortified dried broken rice as a complementary food.
PubMed:Development and application of image analysis to quantify calcium lactate crystals on the surface of smoked Cheddar cheese.
PubMed:Gas-flushed packaging contributes to calcium lactate crystals in Cheddar cheese.
PubMed:Compositional factors associated with calcium lactate crystallization in smoked Cheddar cheese.
PubMed:Enhanced lactose cheese milk does not guarantee calcium lactate crystals in finished cheddar cheese.
PubMed:Calcium fortification systems differ in bioavailability.
PubMed:Calcium deprivation increases the palatability of calcium solutions in rats.
PubMed:Application of central composite design and response surface methodology to the fermentation of olive juice by Lactobacillus plantarum and Debaryomyces hansenii.
PubMed:Calcium from milk or calcium-fortified foods does not inhibit nonheme-iron absorption from a whole diet consumed over a 4-d period.
PubMed:Influence of calcium lactate on the fate of spoilage and pathogenic microorganisms in orange juice.
PubMed:Factors affecting solubility of calcium lactate in aqueous solutions.
PubMed:Factors affecting calcium lactate and liquid expulsion defects in Cheddar cheese.
PubMed:Effect of calcium ions on the solubility of muscular collagen and tenderness of beef meat.
PubMed:Nonstarter lactic acid bacteria and aging temperature affect calcium lactate crystallization in cheddar cheese.
PubMed:Barrier and mechanical properties of milk protein-based edible films containing nutraceuticals.
PubMed:Fermented pork sausage fortified with commercial or hen eggshell calcium lactate.
PubMed:Intragastric calcium infusions support flavor preference learning by calcium-deprived rats.
PubMed:Calcium absorption from three salts and CaSO(4)-fortified bread in premenopausal women.
PubMed:[Preventive and therapeutic effects of calcium lactate on osteoporosis in aged ovariectomized rats].
PubMed:Fate of salmonellae in calcium-supplemented orange juice at refrigeration temperature.
PubMed:Biofilm formation and contamination of cheese by nonstarter lactic acid bacteria in the dairy environment.
PubMed:Survival of salmonellae in pasteurized, refrigerated calcium-fortified orange juice.
PubMed:Effect of selected natural antimicrobials on Baker's yeast activity.
PubMed:The effect of calcium and sodium lactates on growth from spores of Bacillus cereus and Clostridium perfringens in a 'sous-vide' beef goulash under temperature abuse.
PubMed:Biofilms in food processing environments.
PubMed:[Effects of different form calcium on growth and tissue calcium level in rats].
PubMed:Effectiveness of calcium lactate added to food in reducing intraoral demineralization of enamel.
PubMed:Development and use of a selective medium for isolation of Leuconostoc spp. from vegetables and dairy products.
PubMed:Long-term toxicity/carcinogenicity study of calcium lactate in F344 rats.
PubMed:Growth rate, proteolysis and acid production of Streptococcus faecalis subsp. liquefaciens in skim milk with some additives.
PubMed:Effect of calcium lactate in erosion and S. mutans in rats when added to Coca-Cola.
PubMed:Factors influencing the self-selection of calcium in lactating rats.
PubMed:[Subchronic oral toxicity study of calcium lactate in F344 rats].
PubMed:Plaque fluid pH, calcium and phosphorus responses to calcium food additives in a chewable candy.
PubMed:Improved mineral balance in very low birth weight infants fed fortified human milk.
PubMed:Gastrointestinal absorption of calcium from milk and calcium salts.
PubMed:Self-selection of calcium during pregnancy and lactation in rats.
PubMed:Fatty acid balance studies in premature infants fed human milk or formula: effect of calcium supplementation.
PubMed:Effect of calcium lactate and calcium lactophosphate on caries activity in programme-fed rats.
PubMed:Preliminary studies on calcium lactate as an anticaries food additive.
PubMed:[Iron absorption in low birth weight and anemic infants (author's transl)].
Antioxidant, buffer, dough conditioner, yeast nutrient, firming agent, preservative used in food and beverages and other food uses. Dietary supplement (Ca source) Calcium lactate is a white crystalline salt made by the action of lactic acid on calcium carbonate. It is used in foods (as a baking powder) and given medicinally. Its E number is E327.
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