ammonia
azane
 
Notes:
ammonia. a colorless alkaline gas. it is formed in the body during decomposition of organic materials during a large number of metabolically important reactions. Ammonia is a colourless gas with a characteristic pungent odour. Ammonia contributes significantly to the nutritional needs of terrestrial organisms by serving as a precursor to food and fertilizers. Ammonia, either directly or indirectly, is also a building block for the synthesis of many pharmaceuticals. Although in wide use, ammonia is both caustic and hazardous. (Wikipedia)
  • Charkit Chemical
    • Charkit Chemical Corporation
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      Since 1982, Charkit has been committed to expanding the markets we serve and our roster of products and services continues to grow with us. Personal care ingredients now include a substantial array of luxury and exotic components. Substantial inroads have been made in the nutraceutical and resins markets, with a growing roster of versatile and unique ingredients. And we continue to lead the way in our traditional markets such as Metal and Water Treatment, Imaging, Flavor & Fragrance, Aroma and Food. Our Pharmaceutical offerings continue to expand, still anchored by the Boronic Derivatives that meet the demands of Suzuki coupling reactions.
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      Product(s):
      AMMONIA, 7M IN METHANOL
       
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azane (Click)
CAS Number: 7664-41-7Picture of molecule
Other: 208990-07-2
ECHA EINECS - REACH Pre-Reg: 231-635-3
FDA UNII: 5138Q19F1X
Nikkaji Web: J3.748F
Beilstein Number: 3587154
MDL: MFCD00011418
CoE Number: 739
XlogP3-AA: -0.70 (est)
Molecular Weight: 17.03091000
Formula: H3 N
BioActivity Summary: listing
NMR Predictor: Predict (works with chrome or firefox)
Category: acidity regulators
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar: Search
Google Books: Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist: Search
Google Patents: Search
US Patents: Search
EU Patents: Search
Pubchem Patents: Search
PubMed: Search
NCBI: Search
JECFA Food Additive: Ammonia Solution
GSFA Codex: Ammonium hydroxide (527)
Flavis Number: 16.009 (Old)
DG SANTE Food Flavourings: 16.009  ammonia
DG SANTE Food Contact Materials: ammonia
FEMA Number: 4494  ammonia
FDA Mainterm: AMMONIA (ALSO INCLUDES AMMONIUM CHLORIDE)
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Physical Properties:
Appearance: colorless gas (est)
Assay: 95.00 to 100.00 % 
Food Chemicals Codex Listed: No
Melting Point: -78.00 °C. @ 760.00 mm Hg
Boiling Point: -33.35 °C. @ 760.00 mm Hg (est)
Vapor Pressure: 8.750000 mm/Hg @ 21.00 °C.
Vapor Density: 6.0 ( Air = 1 )
Flash Point: 270.00 °F. TCC ( 132.22 °C. )
Soluble in:
 alcohol
 water, 5.101e+004 mg/L @ 25 °C (est)
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Organoleptic Properties:
Odor Type: ammoniacal
Odor Strength: very high ,
recommend smelling in a 0.10 % solution or less
 ammoniacal  
Odor Description:
at 0.10 % in water. 
ammoniacal
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: buffering agents
masking agents
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Suppliers:
American Elements
Ammonia Anhydrous 99%
Odor: characteristic
Use: Anhydrous Ammonia is a compound formed by the combination of two gaseous elements, nitrogen and hydrogen. Ammonia is approximately 82% nitrogen to 18% hydrogen. American Elements offers a broad range of products for hydrogen storage research, advanced fuel cells and battery applications. Hydrogen can easily be generated from renewable energy sources and is the most abundant element in the universe. Hydrogen is produced from various sources such as fossil fuels, water and renewables. Hydrogen is nonpolluting and forms water as a harmless byproduct during use. The challenges associated with the use of hydrogen as a form of energy include developing safe, compact, reliable, and cost-effective hydrogen storage and delivery technologies. Currently, hydrogen can be stored in these three forms: Compressed Hydrogen, Liquid Hydrogen and Chemical Storage.High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
Axsyn
For experimental / research use only.
Ammonia
Charkit Chemical
AMMONIA, 7M IN METHANOL
Kraft Chemical
Ammonia
Sigma-Aldrich: Aldrich
For experimental / research use only.
Ammonia ≥99.99%
Universal Preserv-A-Chem Inc.
STRONG AMMONIA SOLUTION NF
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Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
T N - Toxic, Dangerous for the environment.
R 10 - Flammable.
R 23 - Toxic by inhalation.
R 34 - Causes burns.
R 50 - Very toxic to aquatic organisms.
S 02 - Keep out of the reach of children.
S 09 - Keep container in a well-ventilated place.
S 16 - Keep away from sources of ignition - No Smoking.
S 23 - Do not breath vapour.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
S 45 - In case of accident or if you feel unwell seek medical advice immediately.
S 61 - Avoid release to the environment. Refer to special instructions/safety data sheet.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-human LD50  15 ul/kg
Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 29, 1944.

unreported-man LDLo  132 mg/kg
"Poisoning; Toxicology, Symptoms, Treatments," 2nd ed., Arena, J.M., Springfield, IL, C.C. Thomas, 1970Vol. 2, Pg. 73, 1970.

oral-man TDLo  15 uL/kg
GASTROINTESTINAL: CHANGE IN STRUCTURE OR FUNCTION OF ESOPHAGUS
American Journal of Emergency Medicine. Vol. 3, Pg. 320, 1985.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
inhalation-rat LC50 2000 ppm/4H
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 607, 1969.

inhalation-rabbit LC50 7000 mg/m3
Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 29, 1944.

inhalation-mouse LC50 4230 ppm/1H
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: ATAXIA BEHAVIORAL: TREMOR
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 41, Pg. 1568, 1982.

inhalation-cat LC50 7000 mg/m3/1H
BEHAVIORAL: EXCITEMENT PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)
Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 29, 1944.

inhalation-human LCLo 5000 ppm/5M
Tabulae Biologicae. Vol. 3, Pg. 231, 1933.

inhalation-human TCLo 20 ppm
SENSE ORGANS AND SPECIAL SENSES: ULCERATED NASAL SEPTUM: OLFACTION SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI
Archiv fuer Gewerbepathologie und Gewerbehygiene. Vol. 13, Pg. 528, 1955.

inhalation-mammal (species unspecified) LCLo 5000 ppm/5M
Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 138, Pg. 65, 1928.

inhalation-rabbit LC50 7000 mg/m3/1H
PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) BEHAVIORAL: EXCITEMENT
Journal of Industrial Hygiene and Toxicology. Vol. 26, Pg. 29, 1944.

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Safety in Use Information:
Category: acidity regulators
Recommendation for ammonia usage levels up to:
 not for fragrance use.
 
Maximised Survey-derived Daily Intakes (MSDI-EU): 34.00 (μg/capita/day)
Modified Theoretical Added Maximum Daily Intake (mTAMDI): 110000 (μg/person/day)
Threshold of Concern:1800 (μg/person/day)
Structure Class: I
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 24
Click here to view publication 24
 average usual ppmaverage maximum ppm
baked goods: --
beverages(nonalcoholic): --
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: 500.000001500.00000
egg products: 1000.000003000.00000
fats / oils: --
fish products: 1000.000003000.00000
frozen dairy: --
fruit ices: --
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: 1000.000003000.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: 1000.000003000.00000
milk products: 1000.000003000.00000
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: 1000.000003000.00000
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i).
Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm.
 average usage mg/kgmaximum usage mg/kg
Dairy products, excluding products of category 02.0 (01.0): 500.000001500.00000
Fats and oils, and fat emulsions (type water-in-oil) (02.0): --
Edible ices, including sherbet and sorbet (03.0): --
Processed fruit (04.1): --
Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): --
Confectionery (05.0): 500.000001500.00000
Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): --
Bakery wares (07.0): --
Meat and meat products, including poultry and game (08.0): 500.000001500.00000
Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): 500.000001500.00000
Eggs and egg products (10.0): --
Sweeteners, including honey (11.0): --
Salts, spices, soups, sauces, salads, protein products, etc. (12.0): 500.000001500.00000
Foodstuffs intended for particular nutritional uses (13.0): --
Non-alcoholic ("soft") beverages, excl. dairy products (14.1): --
Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): 500.000001500.00000
Ready-to-eat savouries (15.0): 500.000001500.00000
Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): 500.000001500.00000
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Safety References:
European Food Safety Athority(efsa): Flavor usage levels; Subacute, Subchronic, Chronic and Carcinogenicity Studies; Developmental / Reproductive Toxicity Studies; Genotoxicity Studies...
European Food Safety Authority (EFSA) reference(s):
Flavouring Group Evaluation 46 (FGE.46)[1]: Ammonia and two ammonium salts from chemical group 30
View page or View pdf
Flavouring Group Evaluation 46, Revision 1 (FGE.46Rev1): Ammonia and three ammonium salts from chemical group 30
View page or View pdf
EPI System: View
EPA-Iris: IRIS
ClinicalTrials.gov: search
Daily Med: search
NIOSH International Chemical Safety Cards: search
NIOSH Pocket Guide: search
NLM Hazardous Substances Data Bank: Search
Chemical Carcinogenesis Research Information System: Search
AIDS Citations: Search
Cancer Citations: Search
Toxicology Citations: Search
EPA GENetic TOXicology: Search
Env. Mutagen Info. Center: Search
NLM Developmental and Reproductive Toxicity: Search
EPA Substance Registry Services (TSCA): 7664-41-7
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
Laboratory Chemical Safety Summary : 222
National Institute of Allergy and Infectious Diseases: Data
WISER: UN 1005
WGK Germany: 2
 azane
Chemidplus: 0007664417
EPA/NOAA CAMEO: hazardous materials
RTECS: 7664-41-7
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References:
 azane
NIST Chemistry WebBook: Search Inchi
Canada Domestic Sub. List: 7664-41-7
Pubchem (cid): 222
Pubchem (sid): 134988186
Pherobase: View
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Other Information:
(IUPAC): Atomic Weights of the Elements 2009
(IUPAC): Atomic Weights of the Elements 2009 (pdf)
Videos: The Periodic Table of Videos
tgsc: Atomic Weights use for this web site
(IUPAC): Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS): View
CHEBI: View
CHEMBL: View
KEGG (GenomeNet): C00014
HMDB (The Human Metabolome Database): HMDB00051
FooDB: FDB003908
YMDB (Yeast Metabolome Database): YMDB00091
Export Tariff Code: 2814.10.0000
FDA Listing of Food Additive Status: View
Haz-Map: View
Household Products: Search
MedlinePlusSupp: View
VCF-Online: VCF Volatile Compounds in Food
ChemSpider: View
Wikipedia: View
RSC Learn Chemistry: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
Formulations/Preparations:
•grades: commercial 99.5%; refrigerant 99.97%. •aqueous soln of ammonia is often referred to & labeled as a soln of ammonium hydroxide although there is little ammonium hydroxide present. in commerce, ammonia is avail in form of aqueous soln of varying concn, or as anhydrous ammonia furnished in liquefied form . ammonia in household use contains 10% ammonia & is known as 16 deg ammonia (referring to density in degrees baume, a concn term). •shipping grades or purity: commercial, industrial, refrigeration, electronic, and metallurgical grades all have purity greater than 99.5%. •ammonia solution, more than 10% and not more than 35% ammonia. •ammonia solution, more than 35% and not more than 50% ammonia. •bcmw; active ingredient 7.59% ammonia •busan 1215; active ingredient 7.59% ammonia
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
 buffering agents 
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Occurrence (nature, food, other): note
 apple fruit - 235 mg/kg
Search  Picture
 apple pericarp
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 banana fruit
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 barley - 8130 mg/kg
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 barley seed
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 beef
Search  Picture
 beer
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 beet root - 8800 mg/kg
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 butter
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 cabbage cooked cabbage - 11060 mg/kg
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 cabbage leaf
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 carrot - 3970 mg/kg
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 cauliflower - 6376 mg/kg
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 caviar
Search  Picture
 celery leaf - 19600 mg/kg
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 celery plant
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 celery stem
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 cheese @ 720.00 ± 160 µg%
Data  GC  Search  Picture
 cheese tilsit cheese - 164400 mg/kg
Search  Picture
 chicken fried chicken - 0.2 mg/kg
Search  Picture
 coffee - up to 820 mg/kg
Search  Picture
 corn seed
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 corn sweet corn - 10030 mg/kg
Search  Picture
 egg - up to 9 mg/kg
Search  Picture
 evening-primrose seed
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 fish fatty fish - up to 2928 mg/kg
Search  Picture
 fish lean fish
Search  Picture
 flax seed
Search Trop  Picture
 goosefoot plant
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 hop oil - 10660 mg/kg
Search Trop  Picture
 kale - 15260 mg/kg
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 lettuce - 10260 mg/kg
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 malt - 1192 mg/kg
Search  Picture
 milk
Search  Picture
 mushroom
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 onion
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 pepper bell pepper fruit
Search Trop  Picture
 pork
Search  Picture
 potato chip
Search  Picture
 radish - 8450 mg/kg
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 rhubarb - 6340 mg/kg
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 rice
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 rutabaga
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 shrimp
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 soybean
Search Trop  Picture
 soybean seed
Search Trop  Picture
 spinach leaf
Search Trop  Picture
 squid
Search  Picture
 tea black tea - 400 mg/kg
Search  Picture
 tea leaf
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 tomato
Search  Picture
 wasabi
Search Trop  Picture
 wine red wine - up to 40 mg/kg
Search  Picture
 wine white wine - up to 69 mg/kg
Search  Picture
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Synonyms:
 ammonia anhydrous
 ammonia gas
 azane
 spirit of hartshorn
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