EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

triethylene glycol
ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-

Sponsors

Name:2-[2-(2-hydroxyethoxy)ethoxy]ethanol
CAS Number: 112-27-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:203-953-2
FDA UNII:3P5SU53360
Nikkaji Web:J5.122E
Beilstein Number:0969357
MDL:MFCD00002880
XlogP3:-1.60 (est)
Molecular Weight:150.17438000
Formula:C6 H14 O4
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:solvents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
DG SANTE Food Contact Materials:triethyleneglycol
 
Physical Properties:
Appearance:colorless clear liquid (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 285.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.001320 mm/Hg @ 25.00 °C. (est)
Flash Point: 330.00 °F. TCC ( 165.60 °C. ) (est)
logP (o/w): -1.871 (est)
Soluble in:
 water, 1000000 mg/L @ 25 °C (exp)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: masking agents
solvents
viscosity controlling agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
2,2-(Ethylenedioxy)diethanol 95%
Covalent Chemical
Triethylene Glycol
EMD Millipore
For experimental / research use only.
Triethylene Glycol
Hebei Oukai Biotechnology
For experimental / research use only.
Triethylene Glycol
Kingyoung Bio Technical
Triethylene Glycol
Penta International
TRIETHYLENEGLYCOL
Santa Cruz Biotechnology
For experimental / research use only.
Triethylene Glycol
Sigma-Aldrich
For experimental / research use only.
Triethylene Glycol ReagentPlus®, 99%
Silver Fern Chemical
Triethylene Glycol
Odor: characteristic
Use: Triethylene glycol is used as a solvent and plasticizer in vinyl, resins, and polyesters. It is also used as a dehydrator of natural gas, humectant in printing inks, and as an extraction solvent.
TCI AMERICA
For experimental / research use only.
Triethylene Glycol >99.0%(GC)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 17000 mg/kg
Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 40, 1946.

oral-rabbit LD50 8400 mg/kg
Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 40, 1946.

intravenous-rabbit LD50 1900 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.

intravenous-dog LD50 > 4500 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.

intravenous-guinea pig LD50 10600 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.

oral-guinea pig LD50 7900 mg/kg
Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 40, 1946.

oral-human LDLo 5000 mg/kg
Food and Cosmetics Toxicology. Vol. 17, Pg. 913, 1979.

oral-mammal (species unspecified) LD50 8150 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.

intraperitoneal-mouse LD50 8141 mg/kg
LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA KIDNEY, URETER, AND BLADDER: CHANGES IN BOTH TUBULES AND GLOMERULI BLOOD: CHANGES IN SPLEEN
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 6, Pg. 342, 1947.

intravenous-mouse LD50 6500 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 65, Pg. 89, 1939.

oral-mouse LDLo 18500 mg/kg
Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 1186, 1966.

intravenous-rat LD50 11700 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.

intramuscular-rat LDLo 8400 mg/kg
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 5, 1940.

Dermal Toxicity:
skin-rabbit LD50 > 20 ml/kg
"Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 731, 1969.

subcutaneous-mouse LD50 8750 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 65, Pg. 89, 1939.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: solvents
Recommendation for triethylene glycol usage levels up to:
 not for fragrance use.
 
Recommendation for triethylene glycol flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
NIOSH International Chemical Safety Cards:search
NLM Hazardous Substances Data Bank:Search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):112-27-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :8172
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
2-[2-(2-hydroxyethoxy)ethoxy]ethanol
Chemidplus:0000112276
EPA/NOAA CAMEO:hazardous materials
RTECS:112-27-6
 
References:
 2-[2-(2-hydroxyethoxy)ethoxy]ethanol
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:112-27-6
Pubchem (cid):8172
Pubchem (sid):134975703
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEBI:View
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2905.39.9000
Haz-Map:View
Household Products:Search
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 solvents
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
2,2'-(ethane-1,2-diylbis(oxy))diethanol
2,2'-[ethane-1,2-diylbis(oxy)]diethanol
2,2'-(1,2-ethanediylbis(oxy))bisethanol
2,2'-[1,2-ethanediylbis(oxy)]diethanol
 ethanol, 2,2'-[1,2-ethanediylbis(oxy)]bis-
2,2'-(ethylene dioxy)diethanol
 ethylene glycol dihydroxydiethyl ether
2,2'-(ethylenedioxy)diethanol
2,2'-ethylenedioxybis(ethanol)
2,2'-ethylenedioxydiethanol
2-[2-(2-hydroxy-ethoxy)-ethoxy]-ethanol
1,2-bis(2-hydroxyethoxy)ethane
2-[2-(2-hydroxyethoxy)ethoxy]ethanol
 TEG
 triethyleneglycol
 trigen
 triglycol
 

Articles:

PubMed:Antitumor activity of the protein and small molecule component fractions from Agrocybe aegerita through enhancement of cytokine production.
PubMed:Effect of food/oral-simulating liquids on dynamic mechanical thermal properties of dental nanohybrid light-cured resin composites.
PubMed:Triethylene glycol HO(CH2CH2O)3H.
PubMed:Respiratory peripheral chemosensory irritation, acute and repeated exposure toxicity studies with aerosols of triethylene glycol.
PubMed:Developmental toxicity study with triethylene glycol given by gavage to CD rats and CD-1 mice.
PubMed:Two-step curing: influence on conversion and softening of a dental polymer.
PubMed:[Identification of unknown substances in polyvinyl chloride gloves containing non-phthalate plasticizers].
PubMed:Subchronic peroral toxicity of triethylene glycol in the Fischer 344 rat.
PubMed:Formation of Sterilized Edible Films Based on Caseinates: Effects of Calcium and Plasticizers.
PubMed:Acoustic emissions generated in aged dental composites using a laser thermoacoustic technique.
PubMed:Influence of filler parameters on the mechanical coherence of dental restorative resin composites.
PubMed:Indentation cracking of composite matrix materials.
PubMed:Effect of the antioxidant TK 12627 (Irganox) on monodeiodination and on the levels of messenger ribonucleic acid of 5'-deiodinase type I and spot 14.
PubMed:Solvent degradation and reduced fracture toughness in aged composites.
PubMed:The migration of propylene glycol, mono-, di-, and triethylene glycols from regenerated cellulose film into food.
PubMed:Restorative resins: hardness and strength vs. quantity of remaining double bonds.
PubMed:[Thin layer chromatographic separation and enzymatic detection of carbamate pesticides in plant extracts].
 
Notes:
None found
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