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sodium benzoate
benzoic acid, sodium salt (1:1)

Sponsors

Name:sodium benzoate
CAS Number: 532-32-1Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:208-534-8
FDA UNII:OJ245FE5EU
Nikkaji Web:J3.287E
Beilstein Number:3572467
MDL:MFCD00012463
Molecular Weight:144.10501928
Formula:C7 H5 Na O2
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:antimicrobial agents
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Perfumer and Flavorist:Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 FDA/DG SANTE Petitions, Reviews, Notices:
184.1733 Sodium Benzoate View-review
EU SANCO Sodium benzoate View-review
JECFA Food Additive: Sodium Benzoate
GSFA Codex: Sodium benzoate (211)
DG SANTE Food Additives:sodium benzoate
FEMA Number:3025 sodium benzoate
FDA Mainterm: SODIUM BENZOATE
FDA Regulation:
FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.141 Artificially sweetened fruit jelly.


FDA PART 150 -- FRUIT BUTTERS, JELLIES, PRESERVES, AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Fruit Butters, Jellies, Preserves, and Related Products
Sec. 150.161 Artificially sweetened fruit preserves and jams.


FDA PART 166 -- MARGARINE
Subpart B--Requirements for Specific Standardized Margarine
Sec. 166.110 Margarine.


FDA PART 181 -- PRIOR-SANCTIONED FOOD INGREDIENTS
Subpart B--Specific Prior-Sanctioned Food Ingredients
Sec. 181.23 Antimycotics.


FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1733 Sodium benzoate.
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 99.00 to 100.00
Food Chemicals Codex Listed: Yes
Melting Point: 301.00 to 303.00 °C. @ 760.00 mm Hg
Boiling Point: 248.00 to 249.00 °C. @ 760.00 mm Hg
Vapor Pressure:0.012200 mm/Hg @ 25.00 °C. (est)
Flash Point: 232.00 °F. TCC ( 111.11 °C. )
logP (o/w): 1.895 (est)
Shelf Life: 12.00 month(s) or longer if stored properly.
Storage:store in cool, dry place in tightly sealed containers, protected from heat and light.
 moisture Sensitive.
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 water, 5.56E+05 mg/L @ 25 °C (exp)
Insoluble in:
 alcohol
 
Organoleptic Properties:
Odor Strength:none
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: anticorrosive agents
masking agents
preservatives
 
Suppliers:
Aceto
Sodium Benzoate
Allan Chemical
Sodium Benzoate
American Elements
Sodium Benzoate 99%
Odor: characteristic
Use: Sodium Benzoate is generally immediately available in most volumes. High purity, submicron and nanopowder forms may be considered. American Elements produces to many standard grades when applicable, including Mil Spec (military grade); ACS, Reagent and Technical Grade; Food, Agricultural and Pharmaceutical Grade; Optical Grade, USP and EP/BP (European Pharmacopoeia/British Pharmacopoeia) and follows applicable ASTM testing standards.
American International Chemical, LLC.
Sodium Benzoate
Anhui Haibei
Sodium Benzoate
APAC Chemical
Sodium Benzoate
Flavor: characteristic
Sodium Benzoate is primarily used as a food additive and preservative to reduce or inhibit the activity of microorganisms. Sodium benzoate is FDA GRAS (Generally Recognized As Safe) and is also used widely in other applications such as cosmetics, household items, toiletries, emulsions and other products.
BBFY Industrial
Sodium Benzoate
BOC Sciences
For experimental / research use only.
Sodium Benzoate 99%
CG Herbals
Sodium Benzoate
Charkit Chemical
SODIUM BENZOATE NF FCC DUST FREE AGGLOMERATE
Charkit Chemical
SODIUM BENZOATE
Covalent Chemical
Sodium Benzoate
Eastman Chemical
Probenz™ SP Powder Sodium Benzoate, Food Grade, Kosher
Odor: characteristic
Use: Probenz™ SP Powder sodium benzoate is primarily used as a preservative in the food and beverage industries. It is also used as a preservative in personal care applications and as a corrosion inhibitor in automotive and other antifreeze products.
ECSA Chemicals
Sodium Benzoate
Company Profile
EMD Millipore
For experimental / research use only.
Sodium Benzoate
Emerald Kalama Chemical
Kalama® Sodium Benzoate - Dense
99.0%-101.0% of C7H5NaO2, calculated on the anhydrous basis(NF/FCC)
Emerald Kalama Chemical
Kalama® Sodium Benzoate - EDFTM
99.0%-101.0% of C7H5NaO2, calculated on the anhydrous basis(NF/FCC)
Odor: odorless
Emerald Kalama Chemical
Kalama® Sodium Benzoate - Powder
99.0%-101.0% of C7H5NaO2, calculated on the anhydrous basis(NF/FCC)
Emerald Kalama Chemical
Purox® S Grains
99.9min%(m/m)-on dried product
Odor: characteristic
Use: Purox® S has an extremely high purity, which is achieved through the use of Purox® B top quality benzoic acid, produced in the Emerald Kalama Chemical plant in the Netherlands. Its low impurity levels give Purox® S an excellent taste and odor profile, making it the right choice for the most demanding end-product requirements. In addition to its exceptional purity, Purox® S offers outstanding physical properties for consistently high performance in all your handling, production and packaging processes. Thanks to the unique shaping process, Purox® S has almost perfectly round particles with a narrow particle size distribution. The result of this tailor-made particle size distribution is an optimal combination of low dust content, high flow and excellent dissolution properties. Dust-free processing is achieved by the minimal content of small particles, and optimal dissolution performance by the absence of large particles.
Foodchem International
Sodium Benzoate
Graham Chemical
Sodium Benzoate
Kraft Chemical
Sodium Benzoate
Lluch Essence
SODIUM BENZOATE 99%
M&U International
SODIUM BENZOATE, Kosher
Northwestern Extract
Sodium Benzoate FCC
Penta International
SODIUM BENZOATE N.F., Kosher
Penta International
SODIUM BENZOATE, Kosher
Prinova
Sodium Benzoate
Qingdao Dacon Trading
Sodium Benzoate
Sigma-Aldrich
Sodium benzoate, ≥99%, FCC, FG
Certified Food Grade Products
Silver Fern Chemical
Sodium Benzoate
Odor: characteristic
Use: Sodium Benzoate is widely used as a food preservative, but also has common applications in pharmaceuticals, tobacco products, and as an intermediate for certain dyes. It is often favored for its bacteriostatic and fungistatic properties.
Sinofi Food Ingredients
Sodium Benzoate
Odor: characteristic
Use: Preservative, Cosmetics, Feed, Pharmaceutical, Antimicrobial, Antifungal, Antibacterial, Margarine, Soft Drink, Alcohol Beverage, Beverage Powder, Ice Cream, Candy, Chewing Gum, Icings, Tobacco, Fruit Juice, Puddings, Sauces, Baking Food, Sauage, Food Colors, Milk, Wine, Flavoring Agent, Dyestuff, Toothpaste, Coating, Rubber.
TCI AMERICA
For experimental / research use only.
Sodium Benzoate >98.0%(HPLC)(T)
Zhong Ya Chemical
Sodium Benzoate
 
Safety Information:
Preferred SDS: View
European information :
Most important hazard(s):
None - None found.
S 02 - Keep out of the reach of children.
S 24/25 - Avoid contact with skin and eyes.
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 4070 mg/kg
Journal of Industrial Hygiene and Toxicology. Vol. 30, Pg. 63, 1948.

intraperitoneal-guinea pig LDLo 1400 mg/kg
"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1313, 1935.

intravenous-mouse LD50 1440 mg/kg
Medicinal Chemistry, A Series of Reviews. Vol. 6, Pg. 290, 1963.

oral-mouse LD50 1600 mg/kg
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) LUNGS, THORAX, OR RESPIRATION: DYSPNEA
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 51(1), Pg. 75, 1986.

oral-rabbit LD50 2000 mg/kg
FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 34, 1974.

intravenous-rat LD50 1714 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: TREMOR
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 31, Pg. 253, 1942.

oral-dog LD50 2000 mg/kg
FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 34, 1974.

intramuscular-mouse LD50 2306 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 117, Pg. 307, 1956.

Dermal Toxicity:
subcutaneous-guinea pig LDLo 1000 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 28(1), Pg. 45, 1963.

subcutaneous-rabbit LD50 2000 mg/kg
FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 34, 1974.

subcutaneous-rat LD50 2000 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 28(1), Pg. 45, 1963.

subcutaneous-frog LDLo 100 mg/kg
"Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1313, 1935.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category: antimicrobial agents
Recommendation for sodium benzoate usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
 average usual ppmaverage maximum ppm
baked goods: -300.00000
beverages(nonalcoholic): -350.00000
beverages(alcoholic): --
breakfast cereal: --
cheese: --
chewing gum: -12.00000
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: --
fish products: --
frozen dairy: -38.00000
fruit ices: -38.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: -350.00000
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
 
Safety References:
European Food Safety Authority (EFSA) reference(s):
Assessment of the results of the study by McCann et al. (2007) on the effect of some colours and sodium benzoate on children’s behaviour [1] - Scientific Opinion of the Panel on Food Additives, Flavourings, Processing Aids and Food Contact Materials (AFC)
View page or View pdf
Scientific Opinion on safety and efficacy of sodium benzoate, propionic acid and sodium propionate for pigs, poultry, bovines, sheep, goats, rabbits, horses
View page or View pdf
Scientific Opinion on the safety and efficacy of sodium benzoate as a silage additive for pigs, poultry, bovines, ovines, goats, rabbits and horses
View page or View pdf
Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf
Scientific Opinion on the re-evaluation of benzoic acid (E 210), sodium benzoate (E 211), potassium benzoate (E 212) and calcium benzoate (E 213) as food additives
View page or View pdf
EPI System: View
ClinicalTrials.gov:search
Daily Med:search
NIOSH International Chemical Safety Cards:search
NLM Hazardous Substances Data Bank:Search
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
Carcinogenic Potency Database:Search
EPA GENetic TOXicology:Search
Env. Mutagen Info. Center:Search
NLM Developmental and Reproductive Toxicity:Search
EPA Substance Registry Services (TSCA):532-32-1
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :517055
National Institute of Allergy and Infectious Diseases:Data
SCCNFP:opinion
WGK Germany:1
sodium benzoate
Chemidplus:0000532321
RTECS:532-32-1
 
References:
 sodium benzoate
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:532-32-1
Pubchem (cid):517055
Pubchem (sid):134976677
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2009
(IUPAC):Atomic Weights of the Elements 2009 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Everything Added to Food in the United States (EAFUS):View
CHEBI:View
CHEMBL:View
KEGG (GenomeNet):D02277
HMDB (The Human Metabolome Database):Search
FooDB:FDB019869
Export Tariff Code:2916.31.1170
Haz-Map:View
Household Products:Search
ChemSpider:View
Wikipedia:View
RSC Learn Chemistry:View
Formulations/Preparations:
•national formulary , food chemicals codex dense powder, flake, low dusting dense beverage, granular and technical grades available. •a representative all-purpose hand, face and body lotion prepared with cationic emulsifiers contains 0.125% sodium benzoate. •the amount of sodium benzoate permitted in fruit juices is 0.1 wt% and a common rate of addition to apple juice is 0.05-0.075 wt%. •ucephan (kendall-mcgaw). solution (oral) containing 10% each of sodium benzoate and sodium phenylacetate in 100 ml containers.
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 anticorrosive agents
 antifungal
 preservatives
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
 ammonul
 antimol
 benzoate of soda
 benzoate, sodium
 benzoic acid sodium salt
 benzoic acid, sodium salt
 benzoic acid, sodium salt (1:1)
 benzotron
 natrium benzoicum
 sobenate
 sodium benzoate FCC
 sodium benzoate N.F.
 sodium benzoate NF FCC 33 solution
 sodium benzoate NF FCC dust free agglomerate
 sodium benzoate NF FCC powder
 sodiumbenzoate
 

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PubMed:Combinations of antimycotics to inhibit the growth of molds capable of producing 1,3-pentadiene.
PubMed:Olfactory and quantitative analysis of aroma compounds in elder flower (Sambucus nigra L.) drink processed from five cultivars.
PubMed:Sodium benzoate and lactulose for the treatment of hepatic encephalopathy.
 
Notes:
a fungistatic compound that is widely used as a food preservative. it is conjugated to glycine in the liver and excreted as hippuric acid. the sodium salt of benzoic acid. it is used as an antifungal preservative in pharmaceutical preparations and foods. it may also be used as a test for liver function. Antimicrobial preservative in foods, e.g. margarine and artificially sweetened fruit preserves. Flavouring agent and adjuvant Sodium benzoate is a preservative. It is bacteriostatic and fungistatic under acidic conditions. It is used most prevalently in acidic foods such as salad dressings (vinegar), carbonated drinks (carbonic acid), jams and fruit juices (citric acid), pickles (vinegar), and condiments. It is also found in alcohol-based mouthwash and silver polish[citation needed]. It can also be found in cough syrups like Robitussin. Sodium benzoate is declared on a product label as 'sodium benzoate' or E211.
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