swertia chirata leaf extract
extract of the leaves of the indian chiretta, swertia chirata, gentianaceae
 
Notes:
None found
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Name: swertia chirata leaf extract
CAS Number: 97766-44-4 
ECHA EC Number: 307-906-8
Category: astringents
 
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: astringents
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: astringents
Recommendation for swertia chirata leaf extract usage levels up to:
 not for fragrance use.
 
Recommendation for swertia chirata leaf extract flavor usage levels up to:
 not for flavor use.
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Safety References:
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 swertia chirata leaf extract
Chemidplus: 0097766444
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References:
 swertia chirata leaf extract
Pubchem (sid): 135319765
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Other Information:
Wikipedia: View
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 swertia chirata leaf
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Synonyms:
 extract of the leaves of the indian chiretta, swertia chirata, gentianaceae
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Articles:
PubMed: Ethnobotanical perspective of antimalarial plants: traditional knowledge based study.
PubMed: CYP450 mediated inhibition potential of Swertia chirata: An herb from Indian traditional medicine.
PubMed: Amarogentin regulates self renewal pathways to restrict liver carcinogenesis in experimental mouse model.
PubMed: Antibacterial, Antifungal and antioxidant activities of some medicinal plants.
PubMed: Expression of pro-inflammatory interleukin-8 is reduced by ayurvedic decoctions.
PubMed: Insights from the predicted interactions of plant derived compounds to the gluco-corticoid receptor as an alternative to dexa-methasone.
PubMed: Prevention of liver carcinogenesis by amarogentin through modulation of G1/S cell cycle check point and induction of apoptosis.
PubMed: Insights into mechanisms underlying the gut and airways modulatory effects of Swertia chirata.
PubMed: Highlighting the anti-carcinogenic potential of an ayurvedic medicinal plant, Swertia Chirata.
PubMed: Report: analgesic activities of ethanol extract of leaf, stem and their different fractions of Swertia chirata.
PubMed: In vitro antimicrobial activities of different fractions of Swertia chirata ethanolic extract.
PubMed: Protocol for in vitro regeneration and marker glycoside assessment in Swertia chirata Buch-Ham.
PubMed: Assessment of systemic interaction between Swertia chirata extract and its Bioactive constituents in rabbits.
PubMed: Antiviral activity of the Indian medicinal plant extract Swertia chirata against herpes simplex viruses: a study by in-vitro and molecular approach.
PubMed: Simultaneous estimation of mangiferin and four secoiridoid glycosides in rat plasma using liquid chromatography tandem mass spectrometry and its application to pharmacokinetic study of herbal preparation.
PubMed: Liquid chromatography/tandem mass spectrometric study and analysis of xanthone and secoiridoid glycoside composition of Swertia chirata, a potent antidiabetic.
PubMed: Anthelmintic activity of Swertia chirata against gastrointestinal nematodes of sheep.
PubMed: Amarogentin can reduce hyperproliferation by downregulation of Cox-II and upregulation of apoptosis in mouse skin carcinogenesis model.
PubMed: Evaluation of the anticarcinogenic activity of Swertia chirata Buch.Ham, an Indian medicinal plant, on DMBA-induced mouse skin carcinogenesis model.
PubMed: Phenylalanine-independent biosynthesis of 1,3,5,8-tetrahydroxyxanthone. A retrobiosynthetic NMR study with root cultures of Swertia chirata.
PubMed: Regulation of hazardous exposure by protective exposure: modulation of phase II detoxification and lipid peroxidation by Camellia sinensis and Swertia chirata.
PubMed: In vitro antimalarial activity of extracts of three plants used in the traditional medicine of India.
PubMed: alpha-Glucosidase inhibitory activity of Mangifera indica bark.
PubMed: Screening of various Swertia species extracts in primary monolayer cultures of rat hepatocytes against carbon tetrachloride- and paracetamol-induced toxicity.
PubMed: Tyrosinase inhibitory activity of Bangladeshi indigenous medicinal plants.
PubMed: Production of amarogentin in root cultures of Swertia chirata.
PubMed: Review on some plants of Indian traditional medicine with antioxidant activity.
PubMed: Superoxide-scavenging and prolyl endopeptidase inhibitory activities of Bangladeshi indigenous medicinal plants.
PubMed: Evaluation of the in-vivo activity and toxicity of amarogentin, an antileishmanial agent, in both liposomal and niosomal forms.
PubMed: Antihepatotoxic activity of Swertia chirata on paracetamol and galactosamine induced hepatotoxicity in rats.
PubMed: Antihepatotoxic activity of Swertia chirata on carbon tetrachloride induced hepatotoxicity in rats.
PubMed: Hepatoprotective effect of Swertia chirata on rat.
PubMed: Amarogentin, a naturally occurring secoiridoid glycoside and a newly recognized inhibitor of topoisomerase I from Leishmania donovani.
PubMed: Protective effect of Swertia chirata against indomethacin and other ulcerogenic agent-induced gastric ulcers.
PubMed: Chemical constituents of Gentianaceae XIX: CNS-depressant effects of swertiamarin.
PubMed: Chemical constituents of the gentianaceae V: tetraoxygenated xanthones of Swertia chirata Buch.-Ham.
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