bixa orellana leaf extract
extract of the leaves of bixa orellana, bixaceae
 
Notes:
None found
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Name: bixa orellana leaf extract
CAS Number: 89957-43-7 
ECHA EC Number: 289-561-2
Also Contains: annatto seed
Category: antioxidants, skin conditioning
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FEMA Number: 2103  bixa orellana leaf extract
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Physical Properties:
Food Chemicals Codex Listed: No
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Organoleptic Properties:
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antioxidants
skin conditioning
skin protecting agents
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: antioxidants, skin conditioning
Recommendation for bixa orellana leaf extract usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 3
Click here to view publication 3
 average usual ppmaverage maximum ppm
baked goods: -2000.00000
beverages(nonalcoholic): -25.00000
beverages(alcoholic): --
breakfast cereal: -2000.00000
cheese: --
chewing gum: --
condiments / relishes: --
confectionery froastings: --
egg products: --
fats / oils: -330.00000
fish products: --
frozen dairy: -200.00000
fruit ices: -200.00000
gelatins / puddings: --
granulated sugar: --
gravies: --
hard candy: --
imitation dairy: --
instant coffee / tea: --
jams / jellies: --
meat products: --
milk products: --
nut products: --
other grains: --
poultry: --
processed fruits: --
processed vegetables: --
reconstituted vegetables: --
seasonings / flavors: --
snack foods: --
soft candy: --
soups: --
sugar substitutes: --
sweet sauces: --
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Safety References:
Cancer Citations: Search
Toxicology Citations: Search
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 bixa orellana leaf extract
Chemidplus: 0089957437
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References:
 bixa orellana leaf extract
Pubchem (sid): 135298435
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Other Information:
Export Tariff Code: 1302.19.0000
Wikipedia: View
Read: Under the conditions of intended use - New developments in the FEMA GRAS program and the safety assessment of flavor ingredients
Read: A GRAS assessment program for flavor ingredients
Read: Sensory testing for flavorings with modifying properties. Food Technology
Read: Criteria for the safety evaluation of flavoring substances
Read: A procedure for the safety evaluation of natural flavor complexes used as ingredients in food: essential oils
Read: FEMA Expert Panel: 30 Years of safety evaluation for the flavor industry
Read: Consumption ratio and food predominance of flavoring materials
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 annatto leaf
Search Trop  Picture
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Synonyms:
 achiote leaf extract
 extract of the leaves of bixa orellana, bixaceae
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Articles:
PubMed: Safety and efficacy of Bixa orellana (achiote, annatto) leaf extracts.
PubMed: Suppressions of serotonin-induced increased vascular permeability and leukocyte infiltration by Bixa orellana leaf extract.
PubMed: Chemical constituents and antihistamine activity of Bixa orellana leaf extract.
PubMed: Antimicrobial activity of crude extracts from plant parts and corresponding calli of Bixa orellana L.
PubMed: Antimicrobial activity of the leaves and seeds of Bixa orellana.
PubMed: Antigonorrhoeal activity of plants used in Guatemala for the treatment of sexually transmitted diseases.
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