EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

coleus forskohlii root extract
extract of the roots of coleus forskohlii

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CAS Number: 223748-52-5
FDA UNII: Search
Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: humectants
oral care agents
skin conditioning
skin conditioning - emollient
American International Chemical, LLC.
Indo World Trading
Coleus Forskohlii Herb Extract
Sabinsa Corporation
Coleus Barbatus Extract
Sabinsa Corporation
ForsLean® CG
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic agents
Recommendation for coleus forskohlii root extract usage levels up to:
 not for fragrance use.
Recommendation for coleus forskohlii root extract flavor usage levels up to:
 not for flavor use.
Safety References:
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
coleus barbatus root extract
 coleus barbatus root extract
Pubchem (cas):223748-52-5
Other Information:
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 coleus forskohlii root
Search Trop Picture
 plectranthus barbatus root
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 extract of the roots of coleus forskohlii
 plectranthus barbatus root extract


PubMed:Coleusin factor, a novel anti-cancer diterpenoid, inhibits osteosarcoma growth by inducing bone morphogenetic protein-2 dependent differentiation.
PubMed:Effect of chronic administration of forskolin on glycemia and oxidative stress in rats with and without experimental diabetes.
PubMed:Eco-friendly synthesis of silver and gold nanoparticles with enhanced bactericidal activity and study of silver catalyzed reduction of 4-nitrophenol.
PubMed:A Comparison of the Anti-Staphylococcus aureus Activity of Extracts from Commonly Used Medicinal Plants.
PubMed:Adaptive expression of host cell wall degrading enzymes in fungal disease: an example from Fusarium root rot of medicinal Coleus.
PubMed:Effect of Coleus forskohlii extract on cafeteria diet-induced obesity in rats.
PubMed:Manoyl oxide (13R), the biosynthetic precursor of forskolin, is synthesized in specialized root cork cells in Coleus forskohlii.
PubMed:In vitro plant development and root colonization of Coleus forskohlii by Piriformospora indica.
PubMed:Cyclic AMP synergizes with butyrate in promoting ╬▓-defensin 9 expression in chickens.
PubMed:[In vitro metabolism of forscolin isolated from Coleus forskohlii].
PubMed:A review on botanical species and chemical compounds with appetite suppressing properties for body weight control.
PubMed:Influence of dietary macronutrients on induction of hepatic drug metabolizing enzymes by Coleus forskohlii extract in mice.
PubMed:Metabolic diversity in Coleus forskohlii Briq. of Indian subcontinent.
PubMed:Hepatic cytochrome P450 mediates interaction between warfarin and Coleus forskohlii extract in vivo and in vitro.
PubMed:Forskolin: upcoming antiglaucoma molecule.
PubMed:Matrix solid-phase dispersion extraction for chromatographic analysis of labdane diterpenoids in Coleus forskohlii.
PubMed:Dietary Coleus forskohlii extract generates dose-related hepatotoxicity in mice.
PubMed:Synergy between Glomus fasciculatum and a beneficial Pseudomonas in reducing root diseases and improving yield and forskolin content in Coleus forskohlii Briq. under organic field conditions.
PubMed:In vitro conservation of twenty-three overexploited medicinal plants belonging to the Indian sub continent.
PubMed:Labdane-type diterpenoids from hairy root cultures of Coleus forskohlii, possible intermediates in the biosynthesis of forskolin.
PubMed:The root endophyte fungus Piriformospora indica leads to early flowering, higher biomass and altered secondary metabolites of the medicinal plant, Coleus forskohlii.
PubMed:Coleus forskohlii extract induces hepatic cytochrome P450 enzymes in mice.
PubMed:Clinical efficacy of Coleus forskohlii (Willd.) Briq. (Makandi) in hypertension of geriatric population.
PubMed:[Studies on the chemical constituents of Coleus forskohlii transplanted in Tongcheng and their antitumor activity].
PubMed:Anti-HIV activity of Indian medicinal plants.
PubMed:Isoforskolin pretreatment attenuates lipopolysaccharide-induced acute lung injury in animal models.
PubMed:Oviposition deterrent activity from the ethanolic extract of Pongamia pinnata, Coleus forskohlii, and Datura stramonium leaves against Aedes aegypti and Culex quinquefaciatus.
PubMed:Coleusin factor exerts cytotoxic activity by inducing G0/G1 cell cycle arrest and apoptosis in human gastric cancer BGC-823 cells.
PubMed:Oral administration of an association of forskolin, rutin and vitamins B1 and B2 potentiates the hypotonising effects of pharmacological treatments in POAG patients.
PubMed:In vitro direct shoot regeneration from proximal, middle and distal segment of Coleus forskohlii leaf explants.
PubMed:Effect of selected antiasthmatic plant constituents against micro organism causing upper respiratory tract infection.
PubMed:[Studies on the chemical constituents of Coleus forskohlii].
PubMed:[Chemical constituents in the introduced Coleus forskohlii].
PubMed:Anti-HIV diterpenes from Coleus forskohlii.
PubMed:Monoclonal antibodies against naturally occurring bioactive compounds.
PubMed:Free amino acids in botanicals and botanical preparations.
PubMed:Effects of coleus forskohlii supplementation on body composition and hematological profiles in mildly overweight women.
PubMed:Inhibition of tumor cell proliferation by Coleon C.
PubMed:[Studies on HPLC-ELSD fingerprint of the Coleus forskohlii introduced in Tongcheng].
PubMed:Diterpenes from Coleus forskohlii (WILLD.) BRIQ. (Labiatae).
PubMed:Cell growth inhibitory action of an unusual labdane diterpene, 13-epi-sclareol in breast and uterine cancers in vitro.
PubMed:Two minor diterpene glycosides and an eudesman sesquiterpene from Coleus forskohlii.
PubMed:Potential application of urea-derived herbicides as cytokinins in plant tissue culture.
PubMed:Identification of a forskolin-like molecule in human renal cysts.
PubMed:A forskolin derivative, FSK88, induces apoptosis in human gastric cancer BGC823 cells through caspase activation involving regulation of Bcl-2 family gene expression, dissipation of mitochondrial membrane potential and cytochrome c release.
PubMed:Three new diterpenoids from Coleus forskohlii Briq.
PubMed:Antifungal activity of some coleus species growing in nilgiris.
PubMed:Coleus forskohlii. Monograph.
PubMed:[Studies on the chemical constituents in root of Coleus forskohlii].
PubMed:Simple and rapid method for the isolation of forskolin from Coleus forskohlii by charcoal column chromatography.
PubMed:Two new diterpenoids from Coleus forskohlii.
PubMed:Influence of different AM-fungi on the growth, nutrition and forskolin content of Coleus forskohlii.
PubMed:Effects of Coleus forskohlii on fat storage in ovariectomized rats.
PubMed:Molecular cloning and functional expression of geranylgeranyl pyrophosphate synthase from Coleus forskohlii Briq.
PubMed:Induction of drug metabolism by forskolin: the role of the pregnane X receptor and the protein kinase a signal transduction pathway.
PubMed:Quantitative analysis of forskolin in Coleus forskohlii (Lamiaceae) by reversed-phase liquid chromatography.
PubMed:Biotransformation of low-molecular-weight alcohols by Coleus forskohlii hairy root cultures.
PubMed:Natural therapies for ocular disorders, part two: cataracts and glaucoma.
PubMed:Establishment of forskolin yielding transformed cell suspension cultures of Coleus forskohlii as controlled by different factors.
PubMed:Development of ELISA-analysis methods for the quantification of bioactive natural products in plants, phytomedicines and in humans or similar.
PubMed:Forskolin synthesis in in vitro cultures of Coleus forskohlii Briq transformed with Agrobacterium tumefaciens.
PubMed:Rapid analysis of small samples containing forskolin using monoclonal antibodies.
PubMed:Production of Forskolin by Axenic Coleus forskohlii Roots Cultivated in Shake Flasks and 20-l Glass Jar Bioreactors*.
PubMed:Production of Forskolin in in vitro Cultures of Coleus forskohlii.
PubMed:In vitro propagation of Coleus forskohlii Briq., a threatened medicinal plant.
PubMed:In vitro propagation of Coleus forskohlii Briq. for forskolin synthesis.
PubMed:Insulin and glucagon releasing activity of coleonol (forskolin) and its effect on blood glucose level in normal and alloxan diabetic rats.
PubMed:The effect of adenylate cyclase stimulation on endocochlear potential in the guinea pig.
PubMed:Chonemorphine, stigmasterol, and ecdysterone: steroids isolated through bioassay-directed plant screening programs.
PubMed:Significance of plasma adenosine in the antiplatelet activity of forskolin: potentiation by dipyridamole and dilazep.
PubMed:Variation in forskolin content in the roots of Coleus forskohlii.
PubMed:Formation of forskolin by suspension cultures of Coleus forskohlii.
PubMed:Relaxant effects of forskolin on guinea pig tracheal smooth muscle.
PubMed:Inhibition of IgE-mediated release of histamine and peptide leukotriene from human basophils and mast cells by forskolin.
PubMed:[Protective effect of forskolin in acetylcholine provocation in healthy probands. Comparison of 2 doses with fenoterol and placebo].
PubMed:Forskolin: from an ayurvedic remedy to a modern agent.
PubMed:Forskolin stimulation of naphthylamidase in guinea pig thyroid sections detected with a cytochemical bioassay.
PubMed:Forskolin lowers intraocular pressure by reducing aqueous inflow.
PubMed:Forskolin: a potential antimetastatic agent.
PubMed:Structure-activity relationships for activation of adenylate cyclase by the diterpene forskolin and its derivatives.
PubMed:Forskolin stimulation of acid and pepsinogen secretion by gastric glands.
PubMed:The action of forskolin on muscle cells is modified by hormones, calcium ions and calcium antagonists.
PubMed:[Zum Mechanismus der positiv inotropen und gef├Ąsserweiternden Wirkung von Forskolin aus Coleus forskohlii.]
PubMed:Coleonol and forskolin from Coleus forskohlii.
PubMed:The positive inotropic-acting forskolin, a potent adenylate cyclase activator.
PubMed:Pharmacological studies on coleonol, a hypotensive diterpene from Coleus forskohlii.
None found
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