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rhodiola rosea extract
extract of the whole plant, rhodiola rosea (l.), crassulaceae

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Physical Properties:
Food Chemicals Codex Listed: No
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning - emollient
AuNutra® Industries
Rhodiola Rosea P.E
Changsha Organic Herb
Rhodiola Rosea Extract
Dongguan Meiherb Biotech
Rhodiola Rosea Extract
Odor: characteristic
Use: Rhodiola Rosea extract is prepared from rhodiola root extract, sweet smell and bitter taste. The main ingredients,salidroside,rosavin, tyrosol prevent tumors, enhance immune function, anti-age, anti-fatigue, anti-anoxia, protect radiation, bidirectionally regulate the central nervous system, repair and protect the body, ect. MeiHerb puts great attention on manufacturing improvement and upgrading of natural plant extracts while combining modern plant function research results and providing high-quality whole natural rhodiola rosea extract.
Jiangyin Healthway
Rhodiola Rosea P.E.
New functional food ingredients
P.L. Thomas
RhodioLife™ (Rhodiola rosea)
Plant Extracts
Rhodiola Rosea Extract
Odor: characteristic
Use: Rhodiola Rosea is a plant in the family Crassulaceae that grows in cold regions of the world. Rhodiola Rosea is very effective for improving mood and alleviating depression, improves both physical and mental performance, reduces fatigue,and prevent high altitude sickness.
Tianjin Talent Chemical
Rhodiola Rosea Extract
Xian Yuensun Biological Technology
Rhodiola Rosea Extract, Rosavin 1%-5%, Salidroside 1%-10%
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
Recommendation for rhodiola rosea extract usage levels up to:
 not for fragrance use.
Recommendation for rhodiola rosea extract flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the substantiation of a health claim related to Rhodiola rosea L. extract and reduction of mental fatigue pursuant to Article 13(5) of Regulation (EC) No 1924/2006
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AIDS Citations:Search
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Toxicology Citations:Search
None found
Other Information:
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 rhodiola rosea
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 extract of the whole plant, rhodiola rosea (l.), crassulaceae
 golden root root extract
 rhodiola roanensis extract
 rhodiola rosea subsp. elongata extract
 roseroot extract
 sedum rhodiola extract
 sedum roanense extract
 sedum rosea extract
 sedum rosea var. roanense extract


PubMed:Rhodiola rosea suppresses thymus T-lymphocyte apoptosis by downregulating tumor necrosis factor-α-induced protein 8-like-2 in septic rats.
PubMed:Effects of Two Different Rhodiola rosea Extracts on Primary Human Visceral Adipocytes.
PubMed:Anti-Fatigue Effects of Fermented Rhodiola rosea Extract in Mice.
PubMed:Evaluation of the medicinal herb Graptopetalum paraguayense as a treatment for liver cancer.
PubMed:Rhodiola rosea versus sertraline for major depressive disorder: A randomized placebo-controlled trial.
PubMed:Rhodiola rosea therapy for major depressive disorder: a study protocol for a randomized, double-blind, placebo- controlled trial.
PubMed:Enhancement of Neural Stem Cells after Induction of Depression in Male Albino Rats (A histological & Immunohistochemical Study).
PubMed:Mechanism of action of Rhodiola, salidroside, tyrosol and triandrin in isolated neuroglial cells: an interactive pathway analysis of the downstream effects using RNA microarray data.
PubMed:Application and recovery of ionic liquids in the preparative separation of four flavonoids from Rhodiola rosea by on-line three-dimensional liquid chromatography.
PubMed:Alcohol- and water-based extracts obtained from Rhodiola rosea affect differently the number and metabolic activity of circulating granulocytes in Balb/c mice.
PubMed:Rhodiola rosea (SHR-5), Part 2: A standardized extract of Rhodiola rosea is shown to be effective in the treatment of mild to moderate depression.
PubMed:Antinociceptive and anti-inflammatory effects of Rhodiola rosea L. extract in rats.
PubMed:Concentration-Dependent Effects of Rhodiola Rosea on Long-Term Survival and Stress Resistance of Yeast Saccharomyces Cerevisiae: The Involvement of YAP 1 and MSN2/4 Regulatory Proteins.
PubMed:Rhodiola rosea (SHR-5), Part I: a proprietary root extract of Rhodiola rosea is found to be effective in the treatment of stress-related fatigue.
PubMed:Sambucus nigra extracts inhibit infectious bronchitis virus at an early point during replication.
PubMed:Antihyperglycemic action of rhodiola-aqeous extract in type1-like diabetic rats.
PubMed:Two potent cytochrome P450 2D6 inhibitors found in Rhodiola rosea.
PubMed:Hydroalcoholic extract of Rhodiola rosea L. (Crassulaceae) and its hydrolysate inhibit melanogenesis in B16F0 cells by regulating the CREB/MITF/tyrosinase pathway.
PubMed:Tyrosinase inhibitory effect and antioxidative activities of fermented and ethanol extracts of Rhodiola rosea and Lonicera japonica.
PubMed:Tyrosol and its analogues inhibit alpha-melanocyte-stimulating hormone induced melanogenesis.
PubMed:Rhodiola rosea L. extract and its active compound salidroside antagonized both induction and reinstatement of nicotine place preference in mice.
PubMed:Rhodiola rosea Impairs Acquisition and Expression of Conditioned Place Preference Induced by Cocaine.
PubMed:Evaluation of Rhodiola rosea supplementation on skeletal muscle damage and inflammation in runners following a competitive marathon.
PubMed:Characterization of the anxiolytic activity of Nunavik Rhodiola rosea.
PubMed:Evaluation of molecular chaperons Hsp72 and neuropeptide Y as characteristic markers of adaptogenic activity of plant extracts.
PubMed:Synergistic interactions between the antinociceptive effect of Rhodiola rosea extract and B vitamins in the mouse formalin test.
PubMed:Pharmacological classification of herbal extracts by means of comparison to spectral EEG signatures induced by synthetic drugs in the freely moving rat.
PubMed:A Rhodiola rosea root extract protects skeletal muscle cells against chemically induced oxidative stress by modulating heat shock protein 70 (HSP70) expression.
PubMed:Prevention of torsion-induced testicular injury by Rhodiola rosea.
PubMed:Alleviation of kidney damage induced by unilateral ureter obstruction in rats by Rhodiola rosea.
PubMed:Effect of ethanol extract of Rhodiola rosea on the early nephropathy in type 2 diabetic rats.
PubMed:Extension of Drosophila lifespan by Rhodiola rosea through a mechanism independent from dietary restriction.
PubMed:Anti-Inflammatory and Neuroprotective Effects of Constituents Isolated from Rhodiola rosea.
PubMed:Plant-based medicines for anxiety disorders, part 2: a review of clinical studies with supporting preclinical evidence.
PubMed:[Evaluating adaptogenic properties of Rhodiola rosea extract in human mononuclear cell culture and rat tissues].
PubMed:Neuroprotective effect of Rhodiola rosea Linn against MPTP induced cognitive impairment and oxidative stress.
PubMed:Rhodiola-water extract induces β-endorphin secretion to lower blood pressure in spontaneously hypertensive rats.
PubMed:Effect of provenance, plant part and processing on extract profiles from cultivated European Rhodiola rosea L. for medicinal use.
PubMed:Increase of myocardial performance by Rhodiola-ethanol extract in diabetic rats.
PubMed:Effect of Hypericum perforatum Extract in an Experimental Model of Binge Eating in Female Rats.
PubMed:Serotonin involvement in Rhodiola rosea attenuation of nicotine withdrawal signs in rats.
PubMed:Effects of a Rhodiola rosea L. extract on the acquisition, expression, extinction, and reinstatement of morphine-induced conditioned place preference in mice.
PubMed:Adaptogens stimulate neuropeptide y and hsp72 expression and release in neuroglia cells.
PubMed:Therapeutic effects and safety of Rhodiola rosea extract WS® 1375 in subjects with life-stress symptoms--results of an open-label study.
PubMed:Rhodiola rosea extract protects human cortical neurons against glutamate and hydrogen peroxide-induced cell death through reduction in the accumulation of intracellular calcium.
PubMed:The golden root, Rhodiola rosea, prolongs lifespan but decreases oxidative stress resistance in yeast Saccharomyces cerevisiae.
PubMed:Dose-dependent in vivo effect of Rhodiola and Echinacea on the mitogen-induced lymphocyte proliferation in mice.
PubMed:Rhodiola rosea extracts and salidroside decrease the growth of bladder cancer cell lines via inhibition of the mTOR pathway and induction of autophagy.
PubMed:Pharmacological evaluation of Potentilla alba L. in mice: adaptogenic and central nervous system effects.
PubMed:Effect of salidroside, active principle of Rhodiola rosea extract, on binge eating.
PubMed:Rosenroot (Rhodiola rosea): traditional use, chemical composition, pharmacology and clinical efficacy.
PubMed:Double-blind, placebo-controlled, randomised study of single dose effects of ADAPT-232 on cognitive functions.
PubMed:Effects of a Rhodiola rosea L. extract on acquisition and expression of morphine tolerance and dependence in mice.
PubMed:Bioactive compounds from northern plants.
PubMed:Pretreatment with Rhodiola rosea extract reduces cognitive impairment induced by intracerebroventricular streptozotocin in rats: implication of anti-oxidative and neuroprotective effects.
PubMed:Evaluation of Rhodiola rosea L. extract on affective and physical signs of nicotine withdrawal in mice.
PubMed:Rhodiola rosea ability to enrich cellular antioxidant defences of cultured human keratinocytes.
PubMed:Antioxidant activity of some plant extracts towards xanthine oxidase, lipoxygenase and tyrosinase.
PubMed:Decreased mitochondrial superoxide levels and enhanced protection against paraquat in Drosophila melanogaster supplemented with Rhodiola rosea.
PubMed:Chronic Rhodiola rosea extract supplementation enforces exhaustive swimming tolerance.
PubMed:[Phytoadaptogens-induced phenomenon similar to ischemic preconditioning].
PubMed:Evidence-based efficacy of adaptogens in fatigue, and molecular mechanisms related to their stress-protective activity.
PubMed:Protection of human cultured cells against oxidative stress by Rhodiola rosea without activation of antioxidant defenses.
PubMed:The influence of supplementation with Rhodiola rosea L. extract on selected redox parameters in professional rowers.
PubMed:Perspective on Roseroot (Rhodiola rosea) studies.
PubMed:The effects of Rhodiola rosea extract on 5-HT level, cell proliferation and quantity of neurons at cerebral hippocampus of depressive rats.
PubMed:Anti-inflammatory activity of Rhodiola rosea--"a second-generation adaptogen".
PubMed:A randomised, double-blind, placebo-controlled, parallel-group study of the standardised extract shr-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue.
PubMed:Constituents of Rhodiola rosea showing inhibitory effect on lipase activity in mouse plasma and alimentary canal.
PubMed:Pharmacokinetic and pharmacodynamic study of interaction of Rhodiola rosea SHR-5 extract with warfarin and theophylline in rats.
PubMed:The influence of Rhodiola quadrifida 50% hydro-alcoholic extract and salidroside on tumor-induced angiogenesis in mice.
PubMed:Effects of Rhodiola rosea L. extract on behavioural and physiological alterations induced by chronic mild stress in female rats.
PubMed:Neuroimmunomodulatory compound for sensitive skin care: in vitro and clinical assessment.
PubMed:A pilot study of Rhodiola rosea (Rhodax) for generalized anxiety disorder (GAD).
PubMed:Phenylalkanoids and monoterpene analogues from the roots of Rhodiola rosea.
PubMed:Influence of the plant extract complex "AdMax" on global gene expression levels in cultured human fibroblasts.
PubMed:[Cardioprotective and antiarrhythmic properties of Rhodiolae roseae preparations].
PubMed:Comparative study of Rhodiola preparations on behavioral despair of rats.
PubMed:Clinical trial of Rhodiola rosea L. extract SHR-5 in the treatment of mild to moderate depression.
PubMed:Efficacy and tolerability of a Rhodiola rosea extract in adults with physical and cognitive deficiencies.
PubMed:Fast disintegrating tablets containing Rhodiola rosea L. extract.
PubMed:Effect of valerian extract preparation (BIM) on the sleep-wake cycle in rats.
PubMed:Rhodiola rosea L. extract reduces stress- and CRF-induced anorexia in rats.
PubMed:Adaptogenic and central nervous system effects of single doses of 3% rosavin and 1% salidroside Rhodiola rosea L. extract in mice.
PubMed:Antioxidative effects of Cinnamomi cassiae and Rhodiola rosea extracts in liver of diabetic mice.
PubMed:Potential of cranberry-based herbal synergies for diabetes and hypertension management.
PubMed:Evaluation of Rhodiola crenulata and Rhodiola rosea for management of type II diabetes and hypertension.
PubMed:Effect of a combination of extract from several plants on cell-mediated and humoral immunity of patients with advanced ovarian cancer.
PubMed:Bioactive compounds from Rhodiola rosea (Crassulaceae).
PubMed:Rhodiola rosea as antioxidant in red blood cells: ultrastructural and hemolytic behaviour.
PubMed:Antiproliferative and antimitotic effect, S phase accumulation and induction of apoptosis and necrosis after treatment of extract from Rhodiola rosea rhizomes on HL-60 cells.
PubMed:In vitro protective effect of Rhodiola rosea extract against hypochlorous acid-induced oxidative damage in human erythrocytes.
PubMed:Extract of Rhodiola rosea radix reduces the level of C-reactive protein and creatinine kinase in the blood.
PubMed:Effect of extracts from Rhodiola rosea and Rhodiola crenulata (Crassulaceae) roots on ATP content in mitochondria of skeletal muscles.
PubMed:Lotaustralin from Rhodiola rosea roots.
PubMed:Acute Rhodiola rosea intake can improve endurance exercise performance.
PubMed:Effects of a commercial herbal-based formula on exercise performance in cyclists.
PubMed:Possible mechanisms underlying the effect of natural preparations on erythropoiesis under conditions of conflict situation.
PubMed:[Comparative evaluation of effects of p-tyrosol and Rhodiola rosea extract on bone marrow cells in vivo].
PubMed:A randomized trial of two different doses of a SHR-5 Rhodiola rosea extract versus placebo and control of capacity for mental work.
PubMed:Phenylpropanoid glycosides from Rhodiola rosea.
PubMed:[Hepatoprotective properties of liquid extract of Rhodiola rosea].
PubMed:[Rhodiola rosea extract for prophylaxis of ischemic cerebral circulation disorder].
PubMed:Effects of adaptogens on granulocytopoiesis during paradoxical sleep deprivation.
PubMed:In vitro antioxidant activity of non-cultivated vegetables of ethnic Albanians in southern Italy.
PubMed:[Screening substances derived from cultures of medicinal plants for antimutagenic activity in the Escherichia coli-bacteriophage lambda system].
PubMed:Rhodiola rosea in stress induced fatigue--a double blind cross-over study of a standardized extract SHR-5 with a repeated low-dose regimen on the mental performance of healthy physicians during night duty.
PubMed:A double-blind, placebo-controlled pilot study of the stimulating and adaptogenic effect of Rhodiola rosea SHR-5 extract on the fatigue of students caused by stress during an examination period with a repeated low-dose regimen.
PubMed:[The effect of the preparation rodakson on the psychophysiological and physical adaptation of students to an academic load].
PubMed:[Mechanism of the anti-arrhythmic effect of Rhodiola rosea extract].
PubMed:[The anti-arrhythmia action of an extract of Rhodiola rosea and of n-tyrosol in models of experimental arrhythmias].
PubMed:[Do endogenous ligands of peripheral mu- and delta-opiate receptors mediate anti-arrhythmic and cardioprotective effects of Rhodiola rosea extract?].
PubMed:[Contribution of the opioid system to realization of inotropic effects of Rhodiola rosea extracts in ischemic and reperfusion heart damage in vitro].
PubMed:[The participation of the mu-, delta- and kappa-opioid receptors in the realization of the anti-arrhythmia effect of Rhodiola rosea].
PubMed:[The experimental evaluation of the efficacy of using a Rhodiola rosea extract for treating odontogenic inflammatory diseases].
PubMed:[The effect of a Rhodiola rosea extract on the incidence of recurrences of a superficial bladder cancer (experimental clinical research)].
PubMed:[The cardioprotective and antiadrenergic activity of an extract of Rhodiola rosea in stress].
PubMed:[Cardiac contractile function following acute cooling of the body and the adaptogenic correction of its disorders].
PubMed:[The anti-arrhythmia effect of Rhodiola rosea and its possible mechanism].
PubMed:[The enhancement of the efficacy of adriamycin by using hepatoprotectors of plant origin in metastases of Ehrlich's adenocarcinoma to the liver in mice].
PubMed:[Mechanism of differential effect of low dose adaptogens on the functional activity of normal and transformed cellular elements in vitro].
PubMed:The role of humoral factors of regenerating liver in the development of experimental tumors and the effect of Rhodiola rosea extract on this process.
PubMed:[The effect of low concentrations of adaptogen solutions on the functional activity of murine bone marrow cells in vitro].
PubMed:Decrease of cyclophosphamide haematotoxicity by Rhodiola rosea root extract in mice with Ehrlich and Lewis transplantable tumors.
PubMed:[Changes in clonogenic properties of bone marrow and transplantable mice tumor cells during combined use of cyclophosphane and biological response modifiers of adaptogenic origin].
PubMed:[Plasma beta-endorphin and stress hormones in stress and adaptation].
PubMed:[Effect of a Rhodiola extract on the tumor process in an experiment].
PubMed:Effects of alcohol aqueous extract from Rhodiola rosea L. roots on learning and memory.
None found
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