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terminalia chebula extract
extract of the myrobalan, terminalia chebula, combretaceae

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Name:terminalia chebula whole plant extract
CAS Number: 90131-48-9
ECHA EC Number:290-359-1
FDA UNII: Search
Category:cosmetic agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Food Chemicals Codex Listed: No
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: astringents
skin conditioning
AuNutra® Industries
Terminalia Chebula P.E.
Charkit Chemical
Indo World Trading
Terminalia Chebula Extract
Triphala Extract
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic agents
Recommendation for terminalia chebula extract usage levels up to:
 not for fragrance use.
Recommendation for terminalia chebula extract flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf

AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
terminalia chebula whole plant extract
 terminalia chebula whole plant extract
Canada Domestic Sub. List:90131-48-9
Pubchem (sid):135333954
Other Information:
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 terminalia chebula
Search Trop Picture
 chebulic myrobalan extract
 extract of the myrobalan, terminalia chebula, combretaceae
 haritaki extract
yellow myrobalan extract
 myrobalanifera citrina extract
 myrobalanus chebula extract
 myrobalanus gangetica extract
 terminalia gangetica extract
 terminalia reticulata extract


PubMed:Analgesic and antipyretic activity of Tri-sa-maw recipe.
PubMed:Acute and sub-chronic toxicity of Tri-sa-maw recipe in rats.
PubMed:Effect of Tri-sa-maw recipe on gastrointestinal regulation and motility. .
PubMed:Evaluation of the Analgesic Activity of Standardized Aqueous Extract of Terminalia chebula in Healthy Human Participants Using Hot Air Pain Model.
PubMed:Triterpenoids from the barks of Terminalia chebula.
PubMed:[Isolation and preparation of gallic acid from Terminalia chebula Retz. with high-speed counter-current chromatography].
PubMed:The effect of Terminalia chebula extract vs. silver sulfadiazine on burn wounds in rats.
PubMed:Terminalia chebula Fructus Inhibits Migration and Proliferation of Vascular Smooth Muscle Cells and Production of Inflammatory Mediators in RAW 264.7.
PubMed:Bioinspired reduced graphene oxide nanosheets using Terminalia chebula seeds extract.
PubMed:Hepatoprotective Effect of Terminalia chebula against t-BHP-Induced Acute Liver Injury in C57/BL6 Mice.
PubMed:Sustained release of a purified tannin component of Terminalia chebula from a titanium implant surface prevents biofilm formation by Staphylococcus aureus.
PubMed:Anti-hyperlipidemic effect of methanol bark extract of Terminalia chebula in male albino Wistar rats.
PubMed:Immunomodulatory effects of triphala and its individual constituents: a review.
PubMed:Comparative evaluation of terminalia chebula extract mouthwash and chlorhexidine mouthwash on plaque and gingival inflammation - 4-week randomised control trial.
PubMed:An in vitro study to determine the effect of Terminalia chebula extract and its formulation on Streptococcus mutans.
PubMed:Anti cariogenic effect of terminalia chebula.
PubMed:[Establishment of the mathematical model for the inhibition on alpha-glycosidase by chemical compositions from Terminalia chebula Retz. based on the liquid chromatographic information].
PubMed:Anti-inflammatory activity of constituents isolated from Terminalia chebula.
PubMed:Evaluation of direct antiviral activity of the Deva-5 herb formulation and extracts of five Asian plants against influenza A virus H3N8.
PubMed:Effect of Extracts of Terminalia chebula on Proliferation of Keratinocytes and Fibroblasts Cells: An Alternative Approach for Wound Healing.
PubMed:Treatment of dermatophytosis by a new antifungal agent 'apigenin'.
PubMed:Azole-synergistic anti-candidal activity of altenusin, a biphenyl metabolite of the endophytic fungus Alternaria alternata isolated from Terminalia chebula Retz.
PubMed:Antibacterial potential of hydroalcoholic extracts of triphala components against multidrug-resistant uropathogenic bacteria--a preliminary report.
PubMed:An in-vivo comparative evaluation of two herbal extracts Emblica officinalis and Terminalia Chebula with chlorhexidine as an anticaries agent: A preliminary study.
PubMed:Evaluation of wound healing property of Terminalia catappa on excision wound models in Wistar rats.
PubMed:Effect of Terminalia chebula extract and chlorhexidine on salivary pH and periodontal health: 2 weeks randomized control trial.
PubMed:Antitussive Efficacy and Safety Profile of Ethyl Acetate Fraction of Terminalia chebula.
PubMed:Anti-inflammatory, anti-lipid peroxidative, antioxidant and membrane stabilizing activities of hydroalcoholic extract of Terminalia chebula fruits.
PubMed:Biological activities of phenolic compounds and triterpenoids from the galls of Terminalia chebula.
PubMed:Extraction, gas chromatography-mass spectrometry analysis and screening of fruits of Terminalia chebula Retz. for its antimicrobial potential.
PubMed:Antitussive Activity of the Water-Extracted Carbohydrate Polymer from Terminalia chebula on Citric Acid-Induced Cough.
PubMed:Screening of medicinal plants for PPARα and PPARγ activation and evaluation of their effects on glucose uptake and 3T3-L1 adipogenesis.
PubMed:Evaluation of three medicinal plants for anti-microbial activity.
PubMed:In vitro evaluation of five different herbal extracts as an antimicrobial endodontic irrigant using real time quantitative polymerase chain reaction.
PubMed:Isolation and identification of a gallotannin 1,2,6-tri-O-galloyl-β-D-glucopyranose from hydroalcoholic extract of Terminalia chebula fruits effective against multidrug-resistant uropathogens.
PubMed:Isolation and characterization of antimicrobial compounds in plant extracts against multidrug-resistant Acinetobacter baumannii.
PubMed:Terminalia chebula extract protects OGD-R induced PC12 cell death and inhibits lps induced microglia activation.
PubMed:Ellagic acid derivatives from Terminalia chebula Retz. downregulate the expression of quorum sensing genes to attenuate Pseudomonas aeruginosa PAO1 virulence.
PubMed:Effectiveness of mouthrinse formulated from ethanol extract of Terminalia chebula fruit on salivary Streptococcus mutans among 12 to 15 year old school children of Belgaum city: a randomized field trial.
PubMed:Biobased green method to synthesise palladium and iron nanoparticles using Terminalia chebula aqueous extract.
PubMed:Study of the release mechanism of Terminalia chebula extract from nanoporous silica gel.
PubMed:Screening for Rho-kinase 2 inhibitory potential of Indian medicinal plants used in management of erectile dysfunction.
PubMed:Curative effect of Terminalia chebula extract on acetic acid-induced experimental colitis: role of antioxidants, free radicals and acute inflammatory marker.
PubMed:Reducing power and iron chelating property of Terminalia chebula (Retz.) alleviates iron induced liver toxicity in mice.
PubMed:Anti-hyperglycemic effect of chebulagic acid from the fruits of Terminalia chebula Retz.
PubMed:Cytoprotective role of the aqueous extract of Terminalia chebula on renal epithelial cells.
PubMed:Inhibitory effect of Terminalia chebula Retz. fruit extracts on digestive enzyme related to diabetes and oxidative stress.
PubMed:Proteomic analysis of Terminalia chebula extract-dependent changes in human lymphoblastic T cell protein expression.
PubMed:Formulation and characterization of a cream containing terminalia chebula extract.
PubMed:Green synthesis of silver nanoparticles using Terminalia chebula extract at room temperature and their antimicrobial studies.
PubMed:Inhibition of Propionibacterium acnes lipase by extracts of Indian medicinal plants.
PubMed:Anti-Arthritic and Analgesic Effect of NDI10218, a Standardized Extract of Terminalia chebula, on Arthritis and Pain Model.
PubMed:Antioxidant and anti-inflammatory activities of Thai medicinal plants in Sahasthara remedy for muscle pain treatment.
PubMed:Spasmogenic Activity of the Seed of Terminalia chebula Retz in Rat Small Intestine: In Vivo and In Vitro Studies.
PubMed:Terminalia chebula mediated green and rapid synthesis of gold nanoparticles.
PubMed:Oral administration of ethyl acetate-soluble portion of Terminalia chebula conferring protection from streptozotocin-induced diabetic mellitus and its complications.
PubMed:Effect of tanniniferous Terminalia chebula extract on rumen biohydrogenation, ∆(9)-desaturase activity, CLA content and fatty acid composition in longissimus dorsi muscle of kids.
PubMed:Antimicrobial Activity of Few Medicinal Plants against Clinically Isolated Human Cariogenic Pathogens-An In Vitro Study.
PubMed:Production of unusual dispiro metabolites in Pestalotiopsis virgatula endophyte cultures: HPLC-SPE-NMR, electronic circular dichroism, and time-dependent density-functional computation study.
PubMed:Mitigation of 2,4-dinitrofluorobenzene-induced atopic dermatitis-related symptoms by Terminalia chebula Retzius.
PubMed:Phytochemical Composition, Antioxidant Activity, and Neuroprotective Effect of Terminalia chebula Retzius Extracts.
PubMed:Evaluation of anticataract potential of Triphala in selenite-induced cataract: In vitro and in vivo studies.
PubMed:Extract from Terminalia chebula seeds protect against experimental ischemic neuronal damage via maintaining SODs and BDNF levels.
PubMed:Comparative analysis of antioxidant and phenolic content of chloroform extract/fraction of Terminalia chebula.
PubMed:Mutagenicity and oral toxicity studies of Terminalia chebula.
PubMed:Terminalia chebula extract acts as a potential NF-κB inhibitor in human lymphoblastic T cells.
PubMed:Antinociceptive activity of chronic administration of different extracts of Terminalia bellerica Roxb. and Terminalia chebula Retz. fruits.
PubMed:Comparative analysis of antioxidant and phenolic content of chloroform extract/fraction of Terminalia chebula.
PubMed:Antiulcerogenic activity of Terminalia chebula fruit in experimentally induced ulcer in rats.
PubMed:Inhibitory effects of Terminalia chebula extract on glycation and endothelial cell adhesion.
PubMed:In vitro and in vivo antiplasmodial activity and cytotoxicity of water extracts of Phyllanthus emblica, Terminalia chebula, and Terminalia bellerica.
PubMed:Molluscicidal activity of Sapindus mukorossi and Terminalia chebula against the freshwater snail Lymnaea acuminata.
PubMed:Biological activities of phenolic compounds isolated from galls of Terminalia chebula Retz. (Combretaceae).
PubMed:Antiplasmodial activity of botanical extracts against Plasmodium falciparum.
PubMed:Anti-arthritic and disease modifying activity of Terminalia chebula Retz. in experimental models.
PubMed:The efficacy and safety of herbal medicines used in the treatment of hyperlipidemia; a systematic review.
PubMed:A new glycosidic flavonoid from Jwarhar mahakashay (antipyretic) Ayurvedic preparation.
PubMed:Preventive effects of chebulic acid isolated from Terminalia chebula on advanced glycation endproduct-induced endothelial cell dysfunction.
PubMed:In vitro anti-aging activities of Terminalia chebula gall extract.
PubMed:Cytochrome P450 inhibition assay for standardized extract of Terminalia chebula Retz.
PubMed:Effect of a novel antiinflammatory polyherbal preparation (Sudarshanam oil) on hematological parameters in Wistar rats.
PubMed:The efficacy of Terminalia chebula rinse on Streptococcus mutans count in saliva and its effect on salivary pH.
PubMed:Comparative study of the antioxidant and reactive oxygen species scavenging properties in the extracts of the fruits of Terminalia chebula, Terminalia belerica and Emblica officinalis.
PubMed:Triterpenoids from two Terminalia species.
PubMed:Effect of 1,2,3,4,6-penta-O-galloyl-beta-D-glucose on elastase and hyaluronidase activities and its type II collagen expression.
PubMed:Antibacterial Activity of Medicinal Plants Against Pathogens causing Complicated Urinary Tract Infections.
PubMed:The diversity of antibacterial compounds of Terminalia species (Combretaceae).
PubMed:Inhibition of hyaluronidase activity of human and rat spermatozoa in vitro and antispermatogenic activity in rats in vivo by Terminalia chebula, a flavonoid rich plant.
PubMed:HPLC-SPE-NMR identification of a novel metabolite containing the benzo[c]oxepin skeleton from the endophytic fungus Pestalotiopsis virgatula culture.
PubMed:Effect of Terminalia chebula aqueous extract on oxidative stress and antioxidant status in the liver and kidney of young and aged rats.
PubMed:Chebulagic acid, a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz., induces apoptosis in COLO-205 cell line.
PubMed:Effects of three different doses of a fruit extract of Terminalia chebula on metabolic components of metabolic syndrome, in a rat model.
PubMed:Abrogation of DEN/Fe-NTA induced carcinogenic response, oxidative damage and subsequent cell proliferation response by Terminalia chebula in kidney of Wistar rats.
PubMed:Long-term effects of Terminalia chebula Retz. on hyperglycemia and associated hyperlipidemia, tissue glycogen content and in vitro release of insulin in streptozotocin induced diabetic rats.
PubMed:Use of an aqueous extract of Terminalia chebula as an anticaries agent: a clinical study.
PubMed:Triphala promotes healing of infected full-thickness dermal wound.
PubMed:Antibacterial properties of traditionally used Indian medicinal plants.
PubMed:Pharmacognostical investigations on triphala churnam.
PubMed:Chemomodulatory effects of Terminalia chebula against nickel chloride induced oxidative stress and tumor promotion response in male Wistar rats.
PubMed:Growth-inhibiting activity of active component isolated from Terminalia chebula fruits against intestinal bacteria.
PubMed:Isolation of chebulic acid from Terminalia chebula Retz. and its antioxidant effect in isolated rat hepatocytes.
PubMed:Preparative isolation of hydrolysable tannins chebulagic acid and chebulinic acid from Terminalia chebula by high-speed counter-current chromatography.
PubMed:Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats.
PubMed:Terminalia chebula (fruit) prevents liver toxicity caused by sub-chronic administration of rifampicin, isoniazid and pyrazinamide in combination.
PubMed:Chromatographic fingerprint analysis--a rational approach for quality assessment of traditional Chinese herbal medicine.
PubMed:In vitro antioxidant studies and free radical reactions of triphala, an ayurvedic formulation and its constituents.
PubMed:Antioxidant effects of aqueous extract of Terminalia chebula in vivo and in vitro.
PubMed:Radiation protection by Terminalia chebula: some mechanistic aspects.
PubMed:Antioxidant activity of ethanolic extract of Terminalia chebula fruit against isoproterenol-induced oxidative stress in rats.
PubMed:Protective effect of Terminalia chebula against lysosomal enzyme alterations in isoproterenol-induced cardiac damage in rats.
PubMed:Effect of certain bioactive plant extracts on clinical isolates of beta-lactamase producing methicillin resistant Staphylococcus aureus.
PubMed:Safety of a Novel Botanical Extract Formula for Ameliorating Allergic rhinitis. Part II.
PubMed:Studies on the aqueous extract of Terminalia chebula as a potent antioxidant and a probable radioprotector.
PubMed:Cytoprotective effect on oxidative stress and inhibitory effect on cellular aging of Terminalia chebula fruit.
PubMed:Protective effect of Terminalia chebula against experimental myocardial injury induced by isoproterenol.
PubMed:Antihyperglycemic effect of water extract of dry fruits ofTerminalia chebula in experimental diabetes mellitus.
PubMed:Screening South Indian medicinal plants for antifungal activity against cutaneous pathogens.
PubMed:Safety of a novel botanical extract formula for ameliorating allergic rhinitis.
PubMed:Influence of Terminalia chebula on dermal wound healing in rats.
PubMed:Inhibition of cancer cell growth by crude extract and the phenolics of Terminalia chebula retz. fruit.
PubMed:Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property.
PubMed:Antibacterial activity of black myrobalan (Terminalia chebula Retz) against Helicobacter pylori.
PubMed:Protection of epithelial cells against influenza A virus by a plant derived biological response modifier Ledretan-96.
PubMed:Potential of the aqueous extract of Terminalia chebula as an anticaries agent.
PubMed:Antimutagenicity of hydrolyzable tannins from Terminalia chebula in Salmonella typhimurium.
PubMed:[Cytomegalovirus infection and its possible treatment with herbal medicines].
PubMed:Immunosuppressive effects of gallic acid and chebulagic acid on CTL-mediated cytotoxicity.
PubMed:Extraction and purification of effective antimicrobial constituents of Terminalia chebula RETS. against methicillin-resistant Staphylococcus aureus.
PubMed:Activity of a crude extract formulation in experimental hepatic amoebiasis and in immunomodulation studies.
PubMed:Prophylactic treatment of cytomegalovirus infection with traditional herbs.
PubMed:Efficacy of traditional herbal medicines in combination with acyclovir against herpes simplex virus type 1 infection in vitro and in vivo.
PubMed:Inhibitory effects of Egyptian folk medicines on human immunodeficiency virus (HIV) reverse transcriptase.
PubMed:Antimutagenic activity of Terminalia chebula (myroblan) in Salmonella typhimurium.
None found
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