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thymus vulgaris flower/leaf extract
extract of the flowers and leaves of the thyme, thymus vulgaris l., lamiaceae

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Name:thymus vulgaris l. flower/leaf extract
CAS Number: 84929-51-1
ECHA EC Number:284-535-7
FDA UNII: Search
Category:cosmetic, flavor and fragrance agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FDA Mainterm (SATF):84929-51-1 ; THYME, EXTRACT
FDA Regulation:
Subpart A--General Provisions
Sec. 182.20 Essential oils, oleoresins (solvent-free), and natural extractives (including distillates).
Physical Properties:
Food Chemicals Codex Listed: No
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: fragrance
skin conditioning
Lipotec USA
Actiphyte® of Thyme Extract
Extrapone® Thyme GW
Life Essentials - Botanicals
Odor: characteristic
Use: Extrapone® Thyme GW is an extract of dried thyme herb, prepared in water, glycerin and preservatives. Thyme (Thymus Vulgaris L.) used for our Extrapone® is mainly cultivated in Europe. The herb is harvested, cleaned and if necessary comminuted, extracted with water and ethanol (maceration/percolation) and filtrated. The filtrate is concentrated by distillation, prepared in a mixture of water, glycerin and preservatives and clear filtrated after an individual ripening time. 1 kg Extrapone® Thyme GW contains the aqueous-alcoholic soluble ingredients of approx. 0.15 kg dried thyme herb respectively approx. 1 kg fresh thyme herb. Dried plant material - extract (Extrapone® Thyme GW) - ratio 0.15 : 1 Fresh plant material - extract (Extrapone® Thyme GW) - ratio 1 : 1
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic, flavor and fragrance agents
RIFM Fragrance Material Safety Assessment: Search
IFRA Code of Practice Notification of the 49th Amendment to the IFRA Code of Practice
Safety References:
European Food Safety Authority (EFSA) reference(s):

Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
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National Institute of Allergy and Infectious Diseases:Data
thymus vulgaris l. flower/leaf extract
 thymus vulgaris l. flower/leaf extract
Pubchem (sid):135340084
Other Information:
FDA Substances Added to Food (formerly EAFUS):View
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 thyme flower/leaf
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 extract of the flowers and leaves of the thyme, thymus vulgaris l., lamiaceae
 thyme flower/leaf extract
extrapone thyme GW (Symrise)


PubMed:The inhibitory effect of Thymus vulgaris extracts on the planktonic form and biofilm structures of six human pathogenic bacteria.
PubMed:Thymol and Thymus Vulgaris L. activity against UVA- and UVB-induced damage in NCTC 2544 cell line.
PubMed:Anti-adhesion activity of thyme (Thymus vulgaris L.) extract, thyme post-distillation waste, and olive (Olea europea L.) leaf extract against Campylobacter jejuni on polystyrene and intestine epithelial cells.
PubMed:Enriching the drinking water of rats with extracts of Salvia officinalis and Thymus vulgaris increases their resistance to oxidative stress.
PubMed:Comparative effect of propolis of honey bee and some herbal extracts on Candida Albicans.
PubMed:Growth inhibitory and chemo-sensitization effects of naringenin, a natural flavanone purified from Thymus vulgaris, on human breast and colorectal cancer.
PubMed:Modulatory effects of thymol and carvacrol on inflammatory transcription factors in lipopolysaccharide-treated macrophages.
PubMed:A Novel Reduction Strategy of Clarithromycin Resistance in Helicobacter pylori.
PubMed:An investigation of the bactericidal activity of selected essential oils to Aeromonas spp.
PubMed:Extraction of thymol from different varieties of thyme plants using green solvents.
PubMed:Thymus vulgaris (thyme) inhibits proliferation, adhesion, migration, and invasion of human colorectal cancer cells.
PubMed:Antibacterial Activity of Various Plants Extracts Against Antibiotic-resistant Aeromonas hydrophila.
PubMed:In vitro inhibition of human leukemia THP-1 cells by Origanum syriacum L. and Thymus vulgaris L. extracts.
PubMed:Decoction, infusion and hydroalcoholic extract of cultivated thyme: antioxidant and antibacterial activities, and phenolic characterisation.
PubMed:Evaluating the Efficacy of Achillea millefolium and Thymus vulgaris Extracts Against Newcastle Disease Virus in Ovo.
PubMed:Antibacterial and antibiotic-potentiation activities of some Cameroonian food plants against multi-drug resistant gram-negative bacteria.
PubMed:The development and in vitro evaluation of herbal pellets coated with Eudragit FS 30.
PubMed:Phenolic characterization and antimicrobial activity of folk medicinal plant extracts for their applications in olive production.
PubMed:Prospective evaluation of potential toxicity of repeated doses of Thymus vulgaris L. extracts in rats by means of clinical chemistry, histopathology and NMR-based metabonomic approach.
PubMed:Identification and characterization of dimeric oxidation products of p-cymene-2,3-diol isolated from Thymus vulgaris L.
PubMed:Study of total phenol, flavonoids contents and phytochemical screening of various leaves crude extracts of locally grown Thymus vulgaris.
PubMed:Effects of Salvia officinalis and Thymus vulgaris on oxidant-induced DNA damage and antioxidant status in HepG2 cells.
PubMed:The enhancement of antioxidant compounds extracted from Thymus vulgaris using enzymes and the effect of extracting solvent.
PubMed:Larvicidal and cytotoxic activities of extracts from 11 native plants from northeastern Mexico.
PubMed:[In Vitro Effect of Ankaferd Blood StopperĀ®, a Plant Extract Against Mycobacterium tuberculosis Isolates].
PubMed:Evaluation of the control ability of five essential oils against Aspergillus section Nigri growth and ochratoxin A accumulation in peanut meal extract agar conditioned at different water activities levels.
PubMed:Effects of temperature and time on polyphenolic content and antioxidant activity in the pressurized hot water extraction of deodorized thyme (Thymus vulgaris).
PubMed:Therapeutic potential of some plant extracts used in Turkish traditional medicine on streptozocin-induced type 1 diabetes mellitus in rats.
PubMed:Immunomodulatory activity of the water extract of Thymus vulgaris, Thymus daenensis, and Zataria multiflora on dendritic cells and T cells responses.
PubMed:Antioxidative effect of thyme (Thymus vulgaris) in sunflower oil.
PubMed:Effects of Thyme Extract Oils (from Thymus vulgaris, Thymus zygis, and Thymus hyemalis) on Cytokine Production and Gene Expression of oxLDL-Stimulated THP-1-Macrophages.
PubMed:Bioassay-guided fractionation of a thymol-deprived hydrophilic thyme extract and its antispasmodic effect.
PubMed:[Extraction and analysis of chemical components of essential oil in Thymus vulgaris of tissue culture].
PubMed:Antimicrobial activity of food-compatible plant extracts and chitosan against naturally occurring micro-organisms in tomato juice.
PubMed:In vitro effects of some herbs used in Egyptian traditional medicine on viability of protoscolices of hydatid cysts.
PubMed:Cytotoxicity of Thymus vulgaris essential oil towards human oral cavity squamous cell carcinoma.
PubMed:Antifungal activity of extracts of Rosmarinus officinalis and Thymus vulgaris against Aspergillus flavus and A. ochraceus.
PubMed:Biodegradable gelatin-chitosan films incorporated with essential oils as antimicrobial agents for fish preservation.
PubMed:Upper gastrointestinal bleeding in a patient with defective hemostasis successfully treated with ankaferd blood stopper.
PubMed:Inhibition of growth and caseinase production of Pseudomonas aeruginosa and Escherichia coli 28 by combination of low pH and NaCl, potassium sorbate or Thymus vulgaris extract.
PubMed:The efficacy of Ankaferd Blood Stopper in antithrombotic drug-induced primary and secondary hemostatic abnormalities of a rat-bleeding model.
PubMed:Comparison of Thymus vulgaris (Thyme), Achillea millefolium (Yarrow) and propolis hydroalcoholic extracts versus systemic glucantime in the treatment of cutaneous leishmaniasis in balb/c mice.
PubMed:Antinociceptive effects of hydroalcoholic extract of Thymus vulgaris.
PubMed:In vivo hemostatic effect of the medicinal plant extract Ankaferd Blood Stopper in rats pretreated with warfarin.
PubMed:Antispasmodic effect of hydroalcoholic extract of Thymus vulgaris on the guinea-pig ileum.
PubMed:SOPHY project: an observational study of vaginal pH, lifestyle and correct intimate hygiene in women of different ages and in different physiopathological conditions. Part II.
PubMed:Inhibition of Streptococcus mutans adhesion to buccal epithelial cells by an aqueous extract of Thymus vulgaris.
PubMed:Effect of oregano (Origanum vulgare L.) and thyme (Thymus vulgaris L.) essential oils on Trypanosoma cruzi (Protozoa: Kinetoplastida) growth and ultrastructure.
PubMed:Antioxidant capacity of some herbs/spices from cameroon: a comparative study of two methods.
PubMed:Remarkable synergies between baicalein and tetracycline, and baicalein and beta-lactams against methicillin-resistant Staphylococcus aureus.
PubMed:Monoterpenoids and their glycosides from the leaf of thyme.
PubMed:A new hydroxyjasmone glucoside and its related compounds from the leaf of thyme.
PubMed:New monoterpene glucoside from the aerial parts of thyme (Thymus vulgaris L.).
PubMed:Isolation and structure elucidation of radical scavengers from Thymus vulgaris leaves.
PubMed:[Influence of spiced feed additives on taste of hen's eggs].
PubMed:Purification and biological activity of acidic polysaccharide from leaves of Thymus vulgaris L.
PubMed:Purification and characterization of anti-complementary polysaccharide from leaves of Thymus vulgaris L.
PubMed:Inhibition of Aeromonas caviae and A. sobria by sodium choloride, citric acid, ascorbic acid, potassium sorbate and extracts of Thymus vulgaris.
PubMed:Screening of some Palestinian medicinal plants for antibacterial activity.
PubMed:Antispasmodic activity of Thymus vulgaris extract on the isolated guinea-pig trachea: discrimination between drug and ethanol effects.
PubMed:A novel approach to study antibacterial properties of volatile components of selected Indian medicinal herbs.
PubMed:Protein glycation inhibitors from thyme (Thymus vulgaris).
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