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eriobotrya japonica leaf extract
extract of the leaves of the loquat, eriobotrya japonica, rosaceae

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Name:eriobotrya japonica leaf extract
CAS Number: 91770-19-3
ECHA EC Number:294-804-0
FDA UNII: Search
EFSA/JECFA Comments:FEMA GRAS 29 : Derived from the leaves of Eriobotrya japonica, Eriobotrya japonica leaves extract is measured as not less than 2% citric acid; Not less than 2.5% triterpene acids; Not less than 93% non-volatile components including carbohydrates, fat, protein, water.
Category:cosmetic ingredient for skin conditioning
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
PubMed:Search
NCBI:Search
FEMA Number:4933 eriobotrya japonica leaf extract
FDA:No longer provide for the use of these seven synthetic flavoring substances
 
Physical Properties:
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
skin protecting agents
tonic
 
Suppliers:
AuNutra® Industries
Loquat Leaves P.E.
Chemical-navi - Nikkol
LOQUAT LEAF EXTRACT CA
Odor: characteristic
Use: Promotes hair growth and enhances hair thickness. Clinically tested.
Global Essence
Loquat Leaf Extract
Jiangyin Healthway
Loquat Leaf P.E.
New functional food ingredients
Lipotec USA
Actiphyte® of Loquat Leaf Extract
Qingdao Dacon Trading
Loquat Leaf Extract
Xi'an Greena Biotech
Loquat Leaf Extract
Odor: characteristic
Use: Loquat, also known as Eriobotrya japonica,is a large shrub and native to China.Our ursolic acid is Extracted from loquat leaf.As a natural plant triterpenoids,ursolic acid with a variety of biological effects of sedative,anti-inflammatory,anti-bacterial,anti-diabetic,anti-ulcer,lower blood sugar,strengthen the immune system.Meanwhile,ursolic acid is widely used as a medicine and whitening cosmetic raw material as it’s significant antioxidant function.
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
cosmetic ingredient for skin conditioning
Recommendation for eriobotrya japonica leaf extract usage levels up to:
 not for fragrance use.
 
Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS).
The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library
publication number: 29
Click here to view publication 29
 average usual ppmaverage maximum ppm
baked goods: 20.00000100.00000
beverages(nonalcoholic): 5.0000050.00000
beverages(alcoholic): 5.0000050.00000
breakfast cereal: 20.00000100.00000
cheese: 5.0000050.00000
chewing gum: 20.00000200.00000
condiments / relishes: 5.0000050.00000
confectionery froastings: 20.00000200.00000
egg products: 5.0000050.00000
fats / oils: 10.00000100.00000
fish products: 10.00000100.00000
frozen dairy: 10.00000100.00000
fruit ices: 5.0000050.00000
gelatins / puddings: 10.00000100.00000
granulated sugar: 5.0000050.00000
gravies: 20.00000100.00000
hard candy: 20.00000200.00000
imitation dairy: 10.00000100.00000
instant coffee / tea: 5.0000050.00000
jams / jellies: 5.0000050.00000
meat products: 20.00000100.00000
milk products: 5.0000050.00000
nut products: 10.00000100.00000
other grains: 10.00000100.00000
poultry: 20.00000100.00000
processed fruits: 5.0000050.00000
processed vegetables: 5.0000050.00000
reconstituted vegetables: 5.0000050.00000
seasonings / flavors: 10.00000200.00000
snack foods: 10.00000200.00000
soft candy: 20.00000200.00000
soups: 5.00000100.00000
sugar substitutes: 5.0000050.00000
sweet sauces: 5.00000100.00000
 
Safety References:
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
eriobotrya japonica leaf extract
Chemidplus:0091770193
 
References:
 eriobotrya japonica leaf extract
Pubchem (sid):135279571
 
Other Information:
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 loquat leaf
Search Trop Picture
 
Synonyms:
 extract of the leaves of the loquat, eriobotrya japonica, rosaceae
 loquat leaf extract
actiphyte of loquat leaf extract
 loquat leaf extract CA
 loquat leaves P.E.
japanese medlar leaf extract
japanese plum leaf extract
 

Articles:

PubMed:Involvement of multiple phytoene synthase genes in tissue- and cultivar-specific accumulation of carotenoids in loquat.
PubMed:Sucrose induces expression of the sorbitol-6-phosphate dehydrogenase gene in source leaves of loquat.
PubMed:Processing technology investigation of loquat (Eriobotrya japonica) leaf by ultra-performance liquid chromatography-quadrupole time-of-flight mass spectrometry combined with chemometrics.
PubMed:Anti-Proliferative Activities and Apoptosis Induction by Triterpenes Derived from Eriobotrya japonica in Human Leukemia Cell Lines.
PubMed:Antifibrosis effects of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. leaf in a rat model of bleomycin-induced pulmonary fibrosis.
PubMed:Protective changes of inflammation-related gene expression by the leaves of Eriobotrya japonica in the LPS-stimulated human gingival fibroblast: microarray analysis.
PubMed:In silico discovery of acylated flavonol monorhamnosides from Eriobotrya japonica as natural, small-molecular weight inhibitors of XIAP BIR3.
PubMed:Repeated-dose (28 days) oral toxicity study in rats of an antiacne formula (BC-AF) derived from plants.
PubMed:Identification of alpha-glucosidase inhibitors from a new fermented tea obtained by tea-rolling processing of loquat (Eriobotrya japonica) and green tea leaves.
PubMed:Suppression of blood glucose level by a new fermented tea obtained by tea-rolling processing of loquat (Eriobotrya japonica) and green tea leaves in disaccharide-loaded Sprague-Dawley rats.
PubMed:Loquat (Eriobotrya japonica) extracts suppress the adhesion, migration and invasion of human breast cancer cell line.
PubMed:Effect of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. leaf and MAPK signal transduction pathway on inducible nitric oxide synthase expression in alveolar macrophage of chronic bronchitis rats.
PubMed:Increase of theaflavin gallates and thearubigins by acceleration of catechin oxidation in a new fermented tea product obtained by the tea-rolling processing of loquat ( Eriobotrya japonica ) and green tea leaves.
PubMed:Anti-inflammatory effect of triterpenoic Acids of Eriobotrya japonica (Thunb.) Lindl. Leaf on rat model of chronic bronchitis.
PubMed:[Studies on the triterpenes from loquat leaf (Eriobotrya japonica)].
PubMed:Eriobotrya japonica leaf and its triterpenes inhibited lipopolysaccharide-induced cytokines and inducible enzyme production via the nuclear factor-kappaB signaling pathway in lung epithelial cells.
PubMed:The differential effect of Eriobotrya japonica hydrophilic leaf extract on cytokines production and modulation.
PubMed:Effect of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. leaf on inflammatory cytokine and mediator induction from alveolar macrophages of chronic bronchitic rats.
PubMed:Screening of traditional antidiabetic medicinal plants of Mauritius for possible alpha-amylase inhibitory effects in vitro.
PubMed:Anti-oxidative effect of triterpene acids of Eriobotrya japonica (Thunb.) Lindl. leaf in chronic bronchitis rats.
PubMed:Production of bioactive triterpenes by Eriobotrya japonica calli.
PubMed:Megastigmane glycosides and an acylated triterpenoid from Eriobotrya japonica.
 
Notes:
None found
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