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momordica charantia extract
extract of the whole plant of the balsam cucumber, momordica charantia l., cucurbitaceae

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Name:momordica charantia l. whole plant extract
CAS Number: 93333-80-3
ECHA EC Number:297-050-0
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Category:cosmetic agents
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Physical Properties:
Food Chemicals Codex Listed: No
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: astringents
hair conditioning
skin conditioning
AuNutra® Industries
Bitter Melon P.E.
karela extract
Jiangyin Healthway
Bitter Melon Extract
New functional food ingredients
Jiangyin Healthway
Bitter Melon P.E.
Noble Molecular Research
For experimental / research use only.
Bitter Melon Extract
Bitter Melon Extract
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intraperitoneal-mouse LD50 3160 ug/kg
Biochemical Journal. Vol. 186, Pg. 443, 1980.

Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic agents
Recommendation for momordica charantia extract usage levels up to:
 not for fragrance use.
Recommendation for momordica charantia extract flavor usage levels up to:
 not for flavor use.
Safety References:
Toxicology Citations:Search
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
momordica charantia l. whole plant extract
 momordica charantia l. whole plant extract
Pubchem (sid):135350964
Other Information:
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 melon bitter melon
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balsam-apple extract
balsam cucumber extract
bitter cucumber extract
 cucumis argyi extract
 extract of the whole plant of the balsam cucumber, momordica charantia l., cucurbitaceae
bitter gourd extract
 karela extract
bitter melon extract
 momordica charantia fo. abbreviata extract
 momordica charantia var. abbreviata extract
 momordica charantia var. longirostrata extract
 momordica chinensis extract
 momordica elegans extract
 momordica indica extract
 momordica muricata extract
 momordica operculata extract
 momordica sinensis extract
 papayiyo extract
balsam-pear extract
 pepinillo extract
 sicyos fauriei extract
bitter squash extract


PubMed:Biosynthesis of silver nanoparticles using Momordica charantia leaf broth: Evaluation of their innate antimicrobial and catalytic activities.
PubMed:Beneficial role of bitter melon supplementation in obesity and related complications in metabolic syndrome.
PubMed:5β,19-epoxycucurbitane triterpenoids from Momordica charantia and their anti-inflammatory and cytotoxic activity.
PubMed:Reproductive toxicity of Momordica charantia ethanol seed extracts in male rats.
PubMed:Pectic polysaccharide from the green fruits of Momordica charantia (Karela): structural characterization and study of immunoenhancing and antioxidant properties.
PubMed:Antidiabetic Evaluation of Momordica charantia L Fruit Extracts.
PubMed:13-Oxo-9(Z),11(E),15(Z)-octadecatrienoic acid activates peroxisome proliferator-activated receptor γ in adipocytes.
PubMed:Protective effect of Momordica charantia fruit extract on hyperglycaemia-induced cardiac fibrosis.
PubMed:Involvement of liver in diabetes mellitus: herbal remedies.
PubMed:Characterization of a soluble phosphatidic acid phosphatase in bitter melon (Momordica charantia).
PubMed:Momordica charantia seed extract exhibits strong anticoagulant effect by specifically interfering in intrinsic pathway of blood coagulation and dissolves fibrin clot.
PubMed:Oral administration of leaf extracts of Momordica charantia affect reproductive hormones of adult female Wistar rats.
PubMed:Effectiveness of traditional Malaysian vegetables (ulam) in modulating blood glucose levels.
PubMed:Antimicrobial activity and agricultural properties of bitter melon (Momordica charantia L.) grown in northern parts of Turkey: a case study for adaptation.
PubMed:Momordica charantia ointment accelerates diabetic wound healing and enhances transforming growth factor-β expression.
PubMed:Transport in Caco-2 cell monolayers of antidiabetic cucurbitane triterpenoids from Momordica charantia fruits.
PubMed:Optimized aqueous extraction of saponins from bitter melon for production of a saponin-enriched bitter melon powder.
PubMed:In vivo hypoglycemic effect of methanolic fruit extract of Momordica charantia L.
PubMed:Comparative Study of Hydroalcoholic Extracts of Momordica charantia L. against Foodborne Pathogens.
PubMed:New compounds from acid hydrolyzed products of the fruits of Momordica charantia L. and their inhibitory activity against protein tyrosine phosphatas 1B.
PubMed:Differential anti-diabetic effects and mechanism of action of charantin-rich extract of Taiwanese Momordica charantia between type 1 and type 2 diabetic mice.
PubMed:Cucurbitane-type triterpene glycosides from the fruits of Momordica charantia.
PubMed:Effects of Momordica charantia L. on the blood rheological properties in diabetic patients.
PubMed:Wild bitter gourd protects against alcoholic fatty liver in mice by attenuating oxidative stress and inflammatory responses.
PubMed:Impact of Momordica charantia extract on kidney function and structure in mice.
PubMed:In vitro studies on the sensitivity pattern of Plasmodium falciparum to anti-malarial drugs and local herbal extracts.
PubMed:Cucurbitane-type triterpenoids from the leaves of Momordica charantia.
PubMed:Determination of melatonin content in traditional Thai herbal remedies used as sleeping aids.
PubMed:Effect of α, β momorcharin on viability, caspase activity, cytochrome c release and on cytosolic calcium levels in different cancer cell lines.
PubMed:Antidepressant and anxiolytic properties of the methanolic extract of Momordica charantia Linn (Cucurbitaceae) and its mechanism of action.
PubMed:Increase in the free radical scavenging capability of bitter gourd by a heat-drying process.
PubMed:Bitter melon extract attenuating hepatic steatosis may be mediated by FGF21 and AMPK/Sirt1 signaling in mice.
PubMed:An in vitro study on the risk of non-allergic type-I like hypersensitivity to Momordica charantia.
PubMed:Antioxidant and α-glucosidase inhibitory activities of cucurbit fruit vegetables and identification of active and major constituents from phenolic-rich extracts of Lagenaria siceraria and Sechium edule.
PubMed:Structure modeling and antidiabetic activity of a seed protein of Momordica charantia in non-obese diabetic (NOD) mice.
PubMed:Antioxidant properties and quantitative UPLC-MS analysis of phenolic compounds from extracts of fenugreek (Trigonella foenum-graecum) seeds and bitter melon (Momordica charantia) fruit.
PubMed:Cucurbitane Triterpenoid from Momordica charantia Induces Apoptosis and Autophagy in Breast Cancer Cells, in Part, through Peroxisome Proliferator-Activated Receptor γ Activation.
PubMed:Momordica charantia ameliorates insulin resistance and dyslipidemia with altered hepatic glucose production and fatty acid synthesis and AMPK phosphorylation in high-fat-fed mice.
PubMed:Role of GLP-1 in the Hypoglycemic Effects of Wild Bitter Gourd.
PubMed:Antiproliferative and hypoglycemic cucurbitane-type glycosides from the fruits of Momordica charantia.
PubMed:Momordica charantia and its novel polypeptide regulate glucose homeostasis in mice via binding to insulin receptor.
PubMed:Antimigratory Effects of the Methanol Extract from Momordica charantia on Human Lung Adenocarcinoma CL1 Cells.
PubMed:Comprehensive Evaluation of Anti-hyperglycemic Activity of Fractionated Momordica charantia Seed Extract in Alloxan-Induced Diabetic Rats.
PubMed:Bitter melon extract inhibits proliferation of Trypanosoma brucei bloodstream forms in vitro.
PubMed:Comparative study of protective activities of Neospora caninum bradyzoite antigens, NcBAG1, NcBSR4, NcMAG1, and NcSAG4, in a mouse model of acute parasitic infection.
PubMed:Histomorphological Alterations in the Prostate Gland and Epithelium of Seminiferous Tubule of Sprague-Dawley Rats Treated with Methanolic Extract of Momordica charantia Seeds.
PubMed:Momordica charantia Extract Induces Apoptosis in Human Cancer Cells through Caspase- and Mitochondria-Dependent Pathways.
PubMed:In vitro toxicity and antidiabetic activity of a newly developed polyherbal formulation (MAC-ST/001) in streptozotocin-induced diabetic Wistar rats.
PubMed:Wild bitter melon (Momordica charantia Linn. var. abbreviata Ser.) extract and its bioactive components suppress Propionibacterium acnes-induced inflammation.
PubMed:The beneficial effects of Momordica charantia (bitter gourd) on wound healing of rabbit skin.
PubMed:Glycosidic inhibitors of melanogenesis from leaves of Momordica charantia.
PubMed:In vitro modulation of oxidative burst via release of reactive oxygen species from immune cells by extracts of selected tropical medicinal herbs and food plants.
PubMed:Mechanisms underlying decreased hepatic triacylglycerol and cholesterol by dietary bitter melon extract in the rat.
PubMed:Antimalarial activities of medicinal plants traditionally used in the villages of Dharmapuri regions of South India.
PubMed:Cucurbitane triterpenoids from the leaves of Momordica charantia, and their cancer chemopreventive effects and cytotoxicities.
PubMed:Kuguacin J, a triterpeniod from Momordica charantia leaf, modulates the progression of androgen-independent human prostate cancer cell line, PC3.
PubMed:Inhibition of nuclear transcription factor-κB and activation of peroxisome proliferator-activated receptors in HepG2 cells by cucurbitane-type triterpene glycosides from Momordica charantia.
PubMed:Screening of anti-dengue activity in methanolic extracts of medicinal plants.
PubMed:Trypanocide, cytotoxic, and antifungal activities of Momordica charantia.
PubMed:Antimicrobial, antioxidant activities and total phenolic content of Thai medicinal plants used to treat HIV patients.
PubMed:Bitter melon (Momordica charantia) extract suppresses adrenocortical cancer cell proliferation through modulation of the apoptotic pathway, steroidogenesis, and insulin-like growth factor type 1 receptor/RAC-α serine/threonine-protein kinase signaling.
PubMed:Saponins from the traditional medicinal plant Momordica charantia stimulate insulin secretion in vitro.
PubMed:Pharmaceutical and biopharmaceutical evaluation of extracts from different plant parts of indigenous origin for their hypoglycemic responses in rabbits.
PubMed:Momordica charantia extract, a herbal remedy for type 2 diabetes, contains a specific 11β-hydroxysteroid dehydrogenase type 1 inhibitor.
PubMed:Effect of methanolic seed extract of Momordica charantia on body weight and serum cholesterol level of male Sprague-Dawley rats.
PubMed:Bitter melon extract impairs prostate cancer cell-cycle progression and delays prostatic intraepithelial neoplasia in TRAMP model.
PubMed:Influence of Momordica charantia on oxidative stress-induced perturbations in brain monoamines and plasma corticosterone in albino rats.
PubMed:Dietary kakrol (Momordica dioica Roxb.) flesh inhibits triacylglycerol absorption and lowers the risk for development of fatty liver in rats.
PubMed:Isolation and identification of cucurbitane-type triterpenoids with partial agonist/antagonist potential for estrogen receptors from Momordica charantia.
PubMed:Plant extracts as an alternative to control Leucoptera coffeella (Guérin-Mèneville) (Lepidoptera: Lyonetiidae).
PubMed:Induction of G1 arrest and apoptosis in androgen-dependent human prostate cancer by Kuguacin J, a triterpenoid from Momordica charantia leaf.
PubMed:Kuguacin J isolated from Momordica charantia leaves inhibits P-glycoprotein (ABCB1)-mediated multidrug resistance.
PubMed:Wild bitter gourd extract up-regulates mRNA expression of PPARα, PPARγ and their target genes in C57BL/6J mice.
PubMed:Momordica charantia seed extract reduces pre-adipocyte viability, affects lactate dehydrogenase release, and lipid accumulation in 3T3-L1 cells.
PubMed:Modulation of pancreatic β-cells in neonatally streptozotocin-induced type 2 diabetic rats by the ethanolic extract of Momordica charantia fruit pulp.
PubMed:Bioactives from bitter melon enhance insulin signaling and modulate acyl carnitine content in skeletal muscle in high-fat diet-fed mice.
PubMed:Anti-hyperglycemic and anti-oxidative effect of aqueous extract of Momordica charantia pulp and Trigonella foenum graecum seed in alloxan-induced diabetic rats.
PubMed:Cucurbitane triterpenoids from Momordica charantia and their cytoprotective activity in tert-butyl hydroperoxide-induced hepatotoxicity of HepG2 cells.
PubMed:Effects of Momordica charantia on pancreatic histopathological changes associated with streptozotocin-induced diabetes in neonatal rats.
PubMed:Analgesic and antipyretic activities of Momordica charantia Linn. fruits.
PubMed:Chemopreventive and anticarcinogenic effects of Momordica charantia extract.
PubMed:Momordica charantia leaf extract suppresses rat prostate cancer progression in vitro and in vivo.
PubMed:Momordica charantia maintains normal glucose levels and lipid profiles and prevents oxidative stress in diabetic rats subjected to chronic sucrose load.
PubMed:Effect of alcoholic extracts of Indian medicinal plants on the altered enzymatic activities of diabetic rats.
PubMed:Screening for alternative antibiotics: an investigation into the antimicrobial activities of medicinal food plants of Mauritius.
PubMed:alpha-Glucosidase inhibition properties of cucurbitane-type triterpene glycosides from the fruits of Momordica charantia.
PubMed:Effect of aqueous leaf extract of Momordica charantia on intestinal enzyme activities in diarrhoeagenic mice.
PubMed:Hematemesis due to bitter melon (Momordica charantia) extract-induced gastric ulcerations.
PubMed:Bitter melon (Momordica charantia) triterpenoid extract reduces preadipocyte viability, lipid accumulation and adiponectin expression in 3T3-L1 cells.
PubMed:Extraction, quantification, and antioxidant activities of phenolics from pericarp and seeds of bitter melons (Momordica charantia) harvested at three maturity stages (immature, mature, and ripe).
PubMed:Bitter melon: antagonist to cancer.
PubMed:Histological changes in the kidneys of experimental diabetic rats fed with Momordica charantia (bitter gourd) extract.
PubMed:Bitter melon (Momordica charantia) extract inhibits breast cancer cell proliferation by modulating cell cycle regulatory genes and promotes apoptosis.
PubMed:Momordicatin purified from fruits of Momordica charantia is effective to act as a potent antileishmania agent.
PubMed:Evaluation of native and exotic Brazilian plants for anticancer activity.
PubMed:Octanorcucurbitane triterpenoids protect against tert-butyl hydroperoxide-induced hepatotoxicity from the stems of Momordica charantia.
PubMed:In vitro evaluation of antioxidants of fruit extract of Momordica charantia L. on fibroblasts and keratinocytes.
PubMed:Antioxidant Potential of Momordica charantia in Ammonium Chloride-induced Hyperammonemic Rats.
PubMed:Activating effect of momordin, extract of bitter melon (Momordica Charantia L.), on the promoter of human PPARdelta.
PubMed:Complementary and comparative study on hypoglycemic and antihyperglycemic activity of various extracts of Eugenia jambolana seed, Momordica charantia fruits, Gymnema sylvestre, and Trigonella foenum graecum seeds in rats.
PubMed:Bitter melon protects against lipid peroxidation caused by immobilization stress in albino rats.
PubMed:A histological study of the structural changes in the liver of streptozotocin-induced diabetic rats treated with or without Momordica charantia (bitter gourd).
PubMed:Eleostearic Acid inhibits breast cancer proliferation by means of an oxidation-dependent mechanism.
PubMed:Evaluation of larvicidal nature of fleshy fruit wall of Momordica charantia Linn. (family: cucurbitaceae) in the management of mosquitoes.
PubMed:Fruit extracts of Momordica charantia potentiate glucose uptake and up-regulate Glut-4, PPAR gamma and PI3K.
PubMed:Effect of Momordica charantia L. in the resistance to aminoglycosides in methicilin-resistant Staphylococcus aureus.
PubMed:[Antifeedant and antioviposition activities of Momordica charantia leaf ethanol extract against Liriomyza sativae].
PubMed:Relative toxicity of neem fruit, bitter gourd, and castor seed extracts against the larvae of filaria vector, Culex quinquefasciatus (Say).
PubMed:The effect of topical extract of Momordica charantia (bitter gourd) on wound healing in nondiabetic rats and in rats with diabetes induced by streptozotocin.
PubMed:Antiulcer activity of methanolic extract of Momordica charantia L. in rats.
PubMed:Momordica charantia extract on insulin resistance and the skeletal muscle GLUT4 protein in fructose-fed rats.
PubMed:Suppressive effects of wild bitter gourd (Momordica charantia Linn. var. abbreviata ser.) fruit extracts on inflammatory responses in RAW264.7 macrophages.
PubMed:The in vitro antimicrobial activity of fruit and leaf crude extracts of Momordica charantia: a Tanzania medicinal plant.
PubMed:Induction of hepatocyte growth factor production in human dermal fibroblasts and their proliferation by the extract of bitter melon pulp.
PubMed:Teratogenic effect of the water extract of bitter gourd (Momordica charantia) on the Sprague Dawley rats.
PubMed:Pharmacodynamic interaction of Momordica charantia with rosiglitazone in rats.
PubMed:Alpha-eleostearic acid and its dihydroxy derivative are major apoptosis-inducing components of bitter gourd.
PubMed:Effects of alcoholic extract of Momordica charantia (Linn.) whole fruit powder on the pancreatic islets of alloxan diabetic albino rats.
PubMed:Cucurbitane-type triterpenoids from the stems of momordica charantia.
PubMed:Bitter gourd suppresses lipopolysaccharide-induced inflammatory responses.
PubMed:Larvicidal efficacy of five cucurbitaceous plant leaf extracts against mosquito species.
PubMed:Regeneration of beta cells in islets of Langerhans of pancreas of alloxan diabetic rats by acetone extract of Momordica charantia (Linn.) (bitter gourd) fruits.
PubMed:Extracts of Momordica charantia suppress postprandial hyperglycemia in rats.
PubMed:Antiprotozoal and cytotoxic screening of 45 plant extracts from Democratic Republic of Congo.
PubMed:Bitter gourd (Momordica charantia) improves insulin sensitivity by increasing skeletal muscle insulin-stimulated IRS-1 tyrosine phosphorylation in high-fat-fed rats.
PubMed:An experimental evaluation of the antidiabetic and antilipidemic properties of a standardized Momordica charantia fruit extract.
PubMed:Cucurbitane-type triterpenoids from the fruits of Momordica charantia and their cancer chemopreventive effects.
PubMed:In vitro hypoglycemic activity of methanolic extract of some indigenous plants.
PubMed:The reparative effects of Momordica Charantia Linn. extract on HIT-T15 pancreatic beta-cells.
PubMed:Water extracts from Momordica charantia increase glucose uptake and adiponectin secretion in 3T3-L1 adipose cells.
PubMed:Hypoglycaemic and hypotensive effects of Momordica charantia Linn (Cucurbitaceae) whole-plant aqueous extract in rats.
PubMed:Effect of exogenous ATP on Momordica charantia Linn. (Cucurbitaceae) induced inhibition of D-glucose, L-tyrosine and fluid transport across rat everted intestinal sacs in vitro.
PubMed:Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus.
PubMed:Fractionation and identification of 9c, 11t, 13t-conjugated linolenic acid as an activator of PPARalpha in bitter gourd (Momordica charantia L.).
PubMed:Cucurbitane-type triterpenoids from Momordica charantia.
PubMed:Momordica charantia constituents and antidiabetic screening of the isolated major compounds.
PubMed:Slow acting protein extract from fruit pulp of Momordica charantia with insulin secretagogue and insulinomimetic activities.
PubMed:Screening of antihelminthic effects of Indian plant extracts: a preliminary report.
PubMed:Cucurbitane glucosides from Momordica charantia leaves as oviposition deterrents to the leafminer, Liriomyza trifolii.
PubMed:Hypogylcemic activity of aqueous extract of some indigenous plants.
PubMed:Antioxidant activity of five vegetables traditionally consumed by South-Asian migrants in Bradford, Yorkshire, UK.
PubMed:Effects of Momordica charantia L. (Cucurbitaceae) on indomethacin-induced ulcer model in rats.
PubMed:Role of Momordica charantia in maintaining the normal levels of lipids and glucose in diabetic rats fed a high-fat and low-carbohydrate diet.
PubMed:Cucurbitane triterpenoid oviposition deterrent from Momordica charantia to the leafminer, Liriomyza trifolii.
PubMed:Effect of graded doses of Momordica charantia seed extract on rat sperm: scanning electron microscope study.
PubMed:[The hypoglycemic effects of crude polysaccharides extract from Momordica charantia in mice].
PubMed:Induction of interferon-gamma (IFN-gamma) and T helper 1 (Th1) immune response by bitter gourd extract.
PubMed:Beneficial effects of Momordica charantia seeds in the treatment of STZ-induced diabetes in experimental rats.
PubMed:Antioxidant properties of Momordica Charantia (bitter gourd) seeds on Streptozotocin induced diabetic rats.
PubMed:Cucurbitane-type triterpenoids from the fruit of Momordica charantia.
PubMed:Antidiabetic activity of Momordica charantia seeds on streptozotocin induced diabetic rats.
PubMed:Combined treatment of sodium orthovanadate and Momordica charantia fruit extract prevents alterations in lipid profile and lipogenic enzymes in alloxan diabetic rats.
PubMed:[Isolation and purification of ribosome-inactivating proteins from bitter melon seeds by ion exchange chromatographic columns in series].
PubMed:Experimental evidence for in vitro fluid transport in the presence of a traditional medicinal fruit extract across rat everted intestinal sacs.
PubMed:Oxidative stress is the master operator of drug and chemically-induced programmed and unprogrammed cell death: Implications of natural antioxidants in vivo.
PubMed:Effect of Momordica charantia on lipid profile and oral glucose tolerance in diabetic rats.
PubMed:Phytochemical determination and extraction of Momordica charantia fruit and its hypoglycemic potentiation of oral hypoglycemic drugs in diabetes mellitus (NIDDM).
PubMed:The evaluation of nitric oxide scavenging activity of certain Indian medicinal plants in vitro: a preliminary study.
PubMed:Momordica charantia fruit juice stimulates glucose and amino acid uptakes in L6 myotubes.
PubMed:Beneficial effects and mechanism of action of Momordica charantia juice in the treatment of streptozotocin-induced diabetes mellitus in rat.
PubMed:Inhibitory effect of a bitter melon extract on the P-glycoprotein activity in intestinal Caco-2 cells.
PubMed:Inhibition of P-glycoprotein activity and reversal of cancer multidrug resistance by Momordica charantia extract.
PubMed:Cancer preventive potential of Momordica charantia L. against benzo(a)pyrene induced fore-stomach tumourigenesis in murine model system.
PubMed:The effects of bitter melon (Momordica charantia) on serum and liver triglyceride levels in rats.
PubMed:Bitter melon malt vinegar increases daily energy turnover in rats.
PubMed:Suppressive activity of the fruit of Momordica charantia with exercise on blood glucose in type 2 diabetic mice.
PubMed:Momordica charantia extracts inhibit uptake of monosaccharide and amino acid across rat everted gut sacs in-vitro.
PubMed:Tissue specific expression and immunohistochemical localization of glutathione S-transferase in streptozotocin induced diabetic rats: modulation by Momordica charantia (karela) extract.
PubMed:Bitter gourd (Momordica charantia) extract activates peroxisome proliferator-activated receptors and upregulates the expression of the acyl CoA oxidase gene in H4IIEC3 hepatoma cells.
PubMed:Antihyperglycemic effects of three extracts from Momordica charantia.
PubMed:Amelioration of experimental diabetic neuropathy and gastropathy in rats following oral administration of plant (Eugenia jambolana, Mucuna pruriens and Tinospora cordifolia) extracts.
PubMed:Bitter melon (Momordica charantia): a review of efficacy and safety.
PubMed:Comparative evaluation of hypoglycaemic activity of some Indian medicinal plants in alloxan diabetic rats.
PubMed:Prevention of experimental diabetic cataract by Indian Ayurvedic plant extracts.
PubMed:Effects of bitter melon (Momordica charantia l.) or ginger rhizome (Zingiber offifinale rosc) on spontaneous mammary tumorigenesis in SHN mice.
PubMed:The effect of Momordica charantia and Mucuna pruriens in experimental diabetes and their effect on key metabolic enzymes involved in carbohydrate metabolism.
PubMed:In vitro antiplasmodial investigation of medicinal plants from El Salvador.
PubMed:Hypoglycemic activity of the fruit of the Momordica charantia in type 2 diabetic mice.
PubMed:Inhibitory effects of bitter melon (Momordica charantia Linn.) on bacterial mutagenesis and aberrant crypt focus formation in the rat colon.
PubMed:Hypotriglyceridemic and hypocholesterolemic effects of anti-diabetic Momordica charantia (karela) fruit extract in streptozotocin-induced diabetic rats.
PubMed:Stimulation of protein biosynthesis in rat hepatocytes by extracts of Momordica charantia.
PubMed:Prevention of carcinogen-induced mouse skin papilloma by whole fruit aqueous extract of Momordica charantia.
PubMed:Anti-ulcerogenic effect of Momordica charantia L. fruits on various ulcer models in rats.
PubMed:Modulation of xenobiotic metabolism and oxidative stress in chronic streptozotocin-induced diabetic rats fed with Momordica charantia fruit extract.
PubMed:Screening of Turkish anti-ulcerogenic folk remedies for anti-Helicobacter pylori activity.
PubMed:Plants from Puerto Rico with anti-Mycobacterium tuberculosis properties.
PubMed:Antispermatogenic and androgenic activities of Momordica charantia (Karela) in albino rats.
PubMed:Momordica charantia (Bitter Gourd) peel, pulp, seed and whole fruit extract inhibits mouse skin papillomagenesis.
PubMed:Postnatal efficacy of Momordica charantia peel, pulp, seed and whole fruit extract in the detoxication pathway of suckling neonates and lactating mice.
PubMed:Hypoglycaemic action of momordica charantia in normal and diabetic mice.
PubMed:Screening of medicinal plants for induction of somatic segregation activity in Aspergillus nidulans.
PubMed:Anti-diabetic properties and phytochemistry of Momordica charantia L. (Cucurbitaceae).
PubMed:Demonstration of the hypoglycemic action of Momordica charantia in a validated animal model of diabetes.
PubMed:Characterization of the okra mucilage by interaction with Gal, GalNAc and GlcNAc specific lectins.
PubMed:Trypsin and elastase inhibitors from bitter gourd (Momordica charantia LINN.) seeds: purification, amino acid sequences, and inhibitory activities of four new inhibitors.
PubMed:Effect of Momordica charantia on key hepatic enzymes.
PubMed:Hypoglycaemic effect of Momordica charantia extracts in normoglycaemic or cyproheptadine-induced hyperglycaemic mice.
PubMed:Studies on hypoglycemic effects of fruit pulp, seed, and whole plant of Momordica charantia on normal and diabetic model rats.
PubMed:Hypoglycaemic activity of Coccinia indica and Momordica charantia in diabetic rats: depression of the hepatic gluconeogenic enzymes glucose-6-phosphatase and fructose-1,6-bisphosphatase and elevation of both liver and red-cell shunt enzyme glucose-6-phosphate dehydrogenase.
PubMed:[Hypoglycemic effects of Siamese Momordica charantia and Phyllanthus urinaria extracts in streptozotocin-induced diabetic rats (the 1st report)].
PubMed:Method for detecting the lectin activity of Momordica charantia transferred from micro two-dimensional electrophoretic gel on to nitrocellulose.
PubMed:Analgesic effect of Momordica charantia seed extract in mice and rats.
PubMed:Screening of the antimalarial activity of plants of the Cucurbitaceae family.
PubMed:Hypoglycaemic effect of Momordica charantia extracts.
PubMed:Antimutagens from Momordica charantia.
PubMed:Induction of tumor cytotoxic immune cells using a protein from the bitter melon (Momordica charantia).
PubMed:Blood sugar lowering potentiality of selected Cucurbitaceae plants of Indian origin.
PubMed:Effects of long term feeding of acetone extract of Momordica charantia (whole fruit powder) on alloxan diabetic albino rats.
PubMed:Effect of Momordica charantia Linn. pomous aqueous extract on cataractogenesis in murrin alloxan diabetics.
PubMed:Retardation of retinopathy by Momordica charantia L. (bitter gourd) fruit extract in alloxan diabetic rats.
PubMed:Acid-ethanol extractable compounds from fruits and seeds of the bitter gourd Momordica charantia: effects on lipid metabolism in isolated rat adipocytes.
PubMed:Peptides with antilipolytic and lipogenic activities from seeds of the bitter gourd Momordica charantia (family Cucurbitaceae).
PubMed:Oral hypoglycaemic activity of some medicinal plants of Sri Lanka.
PubMed:In vivo antitumor activity of the bitter melon (Momordica charantia).
PubMed:Purification and characterization of a cytostatic factor with anti-viral activity from the bitter melon.
PubMed:Purification and characterization of a cytostatic factor with anti-viral activity from the bitter melon.
PubMed:The cytotoxic and cytostatic effects of the bitter melon (Momordica charantia) on human lymphocytes.
PubMed:The insulin-releasing activity of the tropical plant momordica charantia.
PubMed:Guanylate cyclase activity in human leukemic and normal lymphocytes. Enzyme inhibition and cytotoxicity of plant extracts.
PubMed:Improvement in glucose tolerance due to Momordica charantia (karela).
PubMed:Effects of Momordica charantia L. fruit extract on the testicular function of dog.
PubMed:Inhibition of growth and guanylate cyclase activity of an undifferentiated prostate adenocarcinoma by an extract of the balsam pear (Momordica charantia abbreviata).
PubMed:Clinical trial in patients with diabetes mellitus of an insulin-like compound obtained from plant source.
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