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cinchona calisaya extract
extract of the whole plant, cinchona calisaya, rubiaceae

Supplier Sponsors

Name:	cinchona calisaya extract
CAS Number:	89997-70-6
ECHA EC Number:	289-707-5
FDA UNII:	Search

Category:tonic agents

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

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NCBI:	Search

Physical Properties:

Food Chemicals Codex Listed:

No

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

CosIng:	cosmetic data
Cosmetic Uses:	tonic

Suppliers:

None found

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-mouse LD50 67.50 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Annales Pharmaceutiques Francaises. Vol. 27, Pg. 397, 1969. intraperitoneal-mouse LD50 95 mg/kg BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Annales Pharmaceutiques Francaises. Vol. 27, Pg. 397, 1969.
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
tonic agents
Recommendation for cinchona calisaya extract usage levels up to:
	not for fragrance use.

Recommendation for cinchona calisaya extract flavor usage levels up to:
	not for flavor use.

Safety References:

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

National Institute of Allergy and Infectious Diseases:Data

cinchona calisaya extract

Chemidplus:0089997706

References:

	cinchona calisaya extract
Pubchem (sid):	135290970

Other Information:

Wikipedia:

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

cinchona calisaya
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Synonyms:

yellow	cinchona extract
	cinchona ledgeriana moens extract
	cinchona tree extract
	extract of the whole plant, cinchona calisaya, rubiaceae

Articles:

PubMed:Cinchona alkaloids from Cinchona succirubra and Cinchona ledgeriana.

PubMed:Ability of endophytic filamentous fungi associated with Cinchona ledgeriana to produce Cinchona alkaloids.

PubMed:Bioproduction of Cinchona alkaloids by the endophytic fungus Diaporthe sp. associated with Cinchona ledgeriana.

PubMed:Cinchona alkaloids are also produced by an endophytic filamentous fungus living in cinchona plant.

PubMed:Composition of endophytic fungi living in Cinchona ledgeriana (Rubiaceae).

PubMed:Antioxidant activity of some Jordanian medicinal plants used traditionally for treatment of diabetes.

PubMed:Synthesis and evaluation of new antimalarial analogues of quinoline alkaloids derived from Cinchona ledgeriana Moens ex Trimen.

PubMed:Thermospray Liquid Chromatography/Mass Spectrometry (TSP LC/MS) Analysis of the Alkaloids from Cinchona in vitro Cultures.

PubMed:The distribution of strictosidine-synthase activity and alkaloids in Cinchona plants.

PubMed:High-performance liquid chromatographic-mass spectrometric assay of high-value compounds for pharmaceutical use from plant cell tissue culture: Cinchona alkaloids.

PubMed:Effect of auxin on cytodifferentiation and production of quinoline alkaloids in compact globular structures of Cinchona ledgeriana.

PubMed:Alkaloid Production by Transformed Root Cultures of Cinchona ledgeriana.

PubMed:Isolation of the anthraquinone norsolorinic acid from Cinchona ledgeriana.

PubMed:Effect of Precursors on Growth and Alkaloid Production in Chinchona ledgeriana Leaf-Shoot Organ Cultures.

PubMed:Quinoline Alkaloid Production by Transformed Cultures of Cinchona ledgeriana.

PubMed:A spectrophotometric assay for strictosidine synthase.

PubMed:Toxicity of quinoline alkaloids to cultured Cinchona ledgeriana cells.

PubMed:Effects of Age and Growth Regulators on Growth and Alkaloid Production in Cinchona ledgeriana Leaf-Shoot Organ Cultures.

PubMed:In vitro cultures of Cinchona species : Precursor feeding of C. ledgeriana root organ suspension cultures with L-Tryptophan.

PubMed:Anthraquinones as phytoalexins in cell and tissue cultures of Cinchona spec.

PubMed:Permeabilization of Cinchona ledgeriana cells by dimethylsulphoxide. effects on alkaloid release and long-term membrane integrity.

PubMed:Studies on tissue cultures of the genus Cinchona L. alkaloid production in cell suspension cultures.

PubMed:Alkaloid production by leaf organ, root organ and cell suspension cultures of Cinchona ledgeriana.

PubMed:Identification of the alkaloids and anthraquinones in Cinchona ledgeriana callus cultures.

PubMed:[The leaves of 2 Madagascan cinchonas (Cinchona ledgeriana Moens and C. succirubra Pavon). Particular study of polyphenols (phenolic acids, anthocyans and flavonoids)].

PubMed:The isolation and identification of quininone from Cinchona ledgeriana.

PubMed:THE EFFECT OF LIGHT AND NITROGEN LEVELS ON GROWTH AND ALKALOID CONTENT OF YOUNG PLANTS OF CINCHONA LEDGERIANA.

PubMed:THE EFFECT OF THREE FACTORIAL LEVELS OF NITROGEN AND PHOSPHORUS ON THE GROWTH AND COMPOSITION OF CINCHONA LEDGERIANA.

PubMed:The distribution and interrelationships of the alkaloids in the bark of Cinchona Ledgeriana.

PubMed:Influence of High, Medium, and Low Soil Moisture on Growth and Alkaloid Content of Cinchona ledgeriana.

Notes:

None found

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