EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

vaccinium macrocarpon fruit extract
extract of the fruit of the cranberry, vaccinium macrocarpon, ericaceae

Supplier Sponsors

CAS Number: 91770-88-6
ECHA EC Number:294-875-8
FDA UNII: Y74M3X3345
Category:cosmetic agents, dietary supplements
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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 FDA/DG SANTE Petitions, Reviews, Notices:
GRN 30 P1 Crospovidone-cranberry juice extract View - notice PDF
GRN 30 P2 Crospovidone-cranberry juice extract View - notice PDF
GRN 873 Cranberry extract View - notice PDF
Physical Properties:
Food Chemicals Codex Listed: No
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: astringents
American International Chemical, LLC.
Cranberry Vaccinium Macrocarpon (Cranberry) Fruit Extract
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For experimental / research use only.
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Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
cosmetic agents, dietary supplements
Recommendation for vaccinium macrocarpon fruit extract usage levels up to:
 not for fragrance use.
Recommendation for vaccinium macrocarpon fruit extract flavor usage levels up to:
 not for flavor use.
Safety References:
European Food Safety Authority (EFSA) reference(s):

Scientific Opinion on the substantiation of a health claim related to proanthocyanidins in Urell« and reduction of bacterial colonisation of the urinary tract by inhibition of the adhesion of P-fimbriated E. coli to uroepithelial cells pursuant to Article 13(5) of Regulation (EC) No 1924/2006
View page or View pdf

Safety of cranberry extract powder as a novel food ingredient pursuant to Regulation (EC) No 258/97
View page or View pdf
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EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
vaccinium macrocarpon fruit extract
 vaccinium macrocarpon fruit extract
Pubchem (sid):135278752
Other Information:
Export Tariff Code:1302.19.0000
FDA Listing of Food Additive Status:View
Potential Blenders and core components note
None Found
Potential Uses:
Occurrence (nature, food, other):note
 cranberry fruit
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fruitapone cranberry B (Symrise)
actiphyte of cranberry extract
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 cranberry fruit extract
fruitapone cranberry GT (Symrise)
 extract of the fruit of the cranberry, vaccinium macrocarpon, ericaceae


PubMed:Non-toxic plant metabolites regulate Staphylococcus viability and biofilm formation: a natural therapeutic strategy useful in the treatment and prevention of skin infections.
PubMed:Effect of standardized cranberry extract on the activity and expression of selected biotransformation enzymes in rat liver and intestine.
PubMed:Preventive effects of cranberry products on experimental colitis induced by dextran sulphate sodium in mice.
PubMed:A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice.
PubMed:Cranberry extract standardized for proanthocyanidins promotes the immune response of Caenorhabditis elegans to Vibrio cholerae through the p38 MAPK pathway and HSF-1.
PubMed:Inhibition of Pseudomonas aeruginosa PAO1 adhesion to and invasion of A549 lung epithelial cells by natural extracts.
PubMed:Cost-effectiveness of cranberries vs antibiotics to prevent urinary tract infections in premenopausal women: a randomized clinical trial.
PubMed:Promising results of cranberry in the prevention of oral Candida biofilms.
PubMed:Supplement timing of cranberry extract plays a key role in promoting Caenorhabditis elegans healthspan.
PubMed:Characterization of fruit products by capillary zone electrophoresis and liquid chromatography using the compositional profiles of polyphenols: application to authentication of natural extracts.
PubMed:Cranberry versus placebo in the prevention of urinary infections in multiple sclerosis: a multicenter, randomized, placebo-controlled, double-blind trial.
PubMed:Can cranberry extract and vitamin C + Zn supplements affect the in vivo activity of paraoxonase 1, antioxidant potential, and lipid status?
PubMed:Cysticlean® a highly pac standardized content in the prevention of recurrent urinary tract infections: an observational, prospective cohort study.
PubMed:Enteric-coated, highly standardized cranberry extract reduces risk of UTIs and urinary symptoms during radiotherapy for prostate carcinoma.
PubMed:The longevity effect of cranberry extract in Caenorhabditis elegans is modulated by daf-16 and osr-1.
PubMed:Urinary tract infection prophylaxis in children with neurogenic bladder with cranberry capsules: randomized controlled trial.
PubMed:Capability of Lactobacillus plantarum IFPL935 to catabolize flavan-3-ol compounds and complex phenolic extracts.
PubMed:American cranberry (Vaccinium macrocarpon) extract affects human prostate cancer cell growth via cell cycle arrest by modulating expression of cell cycle regulators.
PubMed:Study on the influence of cranberry extract ┼╗uravit S┬ĚO┬ĚS(┬«) on the properties of uropathogenic Escherichia coli strains, their ability to form biofilm and its antioxidant properties.
PubMed:MicroRNA alterations in Barrett's esophagus, esophageal adenocarcinoma, and esophageal adenocarcinoma cell lines following cranberry extract treatment: Insights for chemoprevention.
PubMed:Inhibition of adhesion of uropathogenic Escherichia coli bacteria to uroepithelial cells by extracts from cranberry.
PubMed:In premenopausal women with recurrent UTI, antibiotics were more effective than capsules of cranberry extract for the prevention of UTI, but resistance was higher in the antibiotic group.
PubMed:Inhibitory effect of cranberry juice on the colonization of Streptococci species: An in vitro study.
PubMed:Oxidative stress and antioxidant status in intensely exercising horses administered nutraceutical extracts.
PubMed:The effect of nondialyzable material (NDM) cranberry extract on formation of contact lens biofilm by Staphylococcus epidermidis.
PubMed:[Effect of cranberry extract capsules taken during the perioperative period upon the post-surgical urinary infection in gynecology].
PubMed:North American cranberry (Vaccinium macrocarpon) stimulates apoptotic pathways in DU145 human prostate cancer cells in vitro.
PubMed:Inhibitory activity of cranberry extract on the bacterial adhesiveness in the urine of women: an ex-vivo study.
PubMed:Growth performance, meat quality, and gut microflora of broiler chickens fed with cranberry extract.
PubMed:Cranberry (Vaccinium macrocarpon) protects against doxorubicin-induced cardiotoxicity in rats.
PubMed:Effect of cranberry drink on bacterial adhesion in vitro and vaginal microbiota in healthy females.
PubMed:Identification of flavonoid and phenolic antioxidants in black currants, blueberries, raspberries, red currants, and cranberries.
PubMed:Cranberry is not effective for the prevention or treatment of urinary tract infections in individuals with spinal cord injury.
PubMed:Prolongevity effects of an oregano and cranberry extract are diet dependent in the Mexican fruit fly (Anastrepha ludens).
PubMed:Towards tooth friendly soft drinks.
PubMed:Growth inhibitory action of cranberry on Helicobacter pylori.
PubMed:Cranberry phytochemical extract inhibits SGC-7901 cell growth and human tumor xenografts in Balb/c nu/nu mice.
PubMed:Cranberry or trimethoprim for the prevention of recurrent urinary tract infections? A randomized controlled trial in older women.
PubMed:Effect of cranberry juice concentrate on chemically-induced urinary bladder cancers.
PubMed:Evaluation of cranberry tablets for the prevention of urinary tract infections in spinal cord injured patients with neurogenic bladder.
PubMed:Can a concentrated cranberry extract prevent recurrent urinary tract infections in women? A pilot study.
PubMed:In vivo inhibition of growth of human tumor lines by flavonoid fractions from cranberry extract.
PubMed:Cranberry phytochemical extracts induce cell cycle arrest and apoptosis in human MCF-7 breast cancer cells.
PubMed:A flavonoid fraction from cranberry extract inhibits proliferation of human tumor cell lines.
PubMed:Effect of cranberry extract on bacteriuria and pyuria in persons with neurogenic bladder secondary to spinal cord injury.
PubMed:Total cranberry extract versus its phytochemical constituents: antiproliferative and synergistic effects against human tumor cell lines.
PubMed:Identification of procyanidins and anthocyanins in blueberries and cranberries (Vaccinium spp.) using high-performance liquid chromatography/mass spectrometry.
PubMed:Cranberry extract inhibits low density lipoprotein oxidation.
a plant species of the family vaccinium known for the sour fruit which is sometimes used for urinary tract infections.
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