boldus leaf oil
essential oil obtained from the leaves of the boldus, peumus boldus, monimiaceae
 
Notes:
The small tree, Peumus Boldus, grows wild in Chile, South America. Its leaves are collected for pharmaceutical purposes, and an essential oil is steam distilled from them. tsca definition 2008: extractives and their physically modified derivatives. peumus boldus, monimiaceae.
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Name: peumus boldus mol. leaf oil
CAS Number: 8022-81-9 
FDA UNII: 7EXH8HY950
CoE Number: 328
Category: cosmetic fragrance agents and aromatic raw materials
 
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Physical Properties:
Appearance: yellow liquid (est)
Food Chemicals Codex Listed: No
Optical Rotation: -1.00 to +2.00
Acid Value: 3.00 max. KOH/g
Soluble in:
 alcohol
Insoluble in:
 water
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Organoleptic Properties:
Odor Type: spicy
Odor Strength: medium
 spicy  solvent  wormwood  
Odor Description:
at 100.00 %. 
spicy solvent wormwood
  
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Cosmetic Information:
CosIng: cosmetic data
Cosmetic Uses: antidandruff agents
perfuming agents
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Suppliers:
 None found
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Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50  130 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 643, 1982.

intraperitoneal-mouse LD50  420 mg/kg
Journal de Pharmacie de Belgique. Vol. 32, Pg. 13, 1977.

Dermal Toxicity:
skin-rabbit LD50 625 mg/kg
Food and Chemical Toxicology. Vol. 20, Pg. 643, 1982.

Inhalation Toxicity:
Not determined
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Safety in Use Information:
Category: cosmetic fragrance agents and aromatic raw materials
contains the following IFRA (Annex) restricted components: (non-analysis max. level reference only)
methyl eugenol Max. Found: <0.80 % and Reason: Potential carcinogenic activity in animals
geraniol Max. Found: <0.40 % and Reason: Sensitization
IFRA: View Standard
Recommendation for boldus leaf oil usage levels up to:
 PROHIBITED: Should not be used as a fragrance ingredient.
 
Recommendation for boldus leaf oil flavor usage levels up to:
 not for flavor use.
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Safety References:
EPA Substance Registry Services (TSCA): 8022-81-9
EPA ACToR: Toxicology Data
EPA Substance Registry Services (SRS): Registry
National Institute of Allergy and Infectious Diseases: Data
 peumus boldus mol. leaf oil
Chemidplus: 0008022819
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References:
 peumus boldus mol. leaf oil
Canada Domestic Sub. List: 8022-81-9
Pubchem (sid): 135328874
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Other Information:
Export Tariff Code: 3301.29.6000
 Typical G.C.
Wikipedia: View
FAO: BASIC PRINCIPLES OF STEAM DISTILLATION
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Potential Blenders and core components note
 
None Found
 
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Potential Uses:
None Found
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Occurrence (nature, food, other): note
 peumus boldus
Search Trop  Picture
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Synonyms:
 boldea boldus leaf oil
 boldea fragrans leaf oil
 boldo leaf oil (peumus boldus mol.)
 boldus leaf oil
 essential oil obtained from the leaves of the boldus, peumus boldus, monimiaceae
 peumus boldus leaf oil
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Articles:
PubMed: Direct identification of phenolic constituents in Boldo Folium (Peumus boldus Mol.) infusions by high-performance liquid chromatography with diode array detection and electrospray ionization tandem mass spectrometry.
PubMed: Anthelmintic effects of phytogenic feed additives in Ascaris suum inoculated pigs.
PubMed: Effect of boldo (Peumus boldus Molina) infusion on lipoperoxidation induced by cisplatin in mice liver.
PubMed: Biosynthesis of ascaridole: iodide peroxidase-catalyzed synthesis of a monoterpene endoperoxide in soluble extracts of Chenopodium ambrosioides fruit.
PubMed: [Peumus boldus Mol., the mother plant of the boldo leaf].
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