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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 9.552e-005 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
| BOC Sciences |
| For experimental / research use only. |
| Germanicol 97.5%
Odor: characteristic Use: Germanicol is a natural compound isolated from the barks of Lecythis pisonis. |
Safety Information:
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| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for germanicol usage levels up to: | | | not for fragrance use.
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| |
| Recommendation for germanicol flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :122857 |
| National Institute of Allergy and Infectious Diseases:Data |
| (3S,4aR,6aS,6aR,6bR,8aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,6a,7,8,9,10,13,14,14a-tetradecahydropicen-3-ol |
| Chemidplus:0000465021 |
References:
| | (3S,4aR,6aS,6aR,6bR,8aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b-octamethyl-1,2,3,4a,5,6,6a,7,8,9,10,13,14,14a-tetradecahydropicen-3-ol |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 122857 |
| Pubchem (cas): | 465-02-1 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| (3S,4aR,6aS,6aR,6bR,8aR,14aR,14bR)-4,4,6a,6b,8a,11,11,14b- | octamethyl-1,2,3,4a,5,6,6a,7,8,9,10,13,14,14a-tetradecahydropicen-3-ol | | | olean-18-en-3-ol, (3beta)- |
Articles:
| PubMed:Strictly Conserved Residues in Euphorbia tirucalli β-Amyrin Cyclase: Trp612 Stabilizes Transient Cation through Cation-π Interaction and CH-π Interaction of Tyr736 with Leu734 Confers Robust Local Protein Architecture. |
| PubMed:Germanicol induces selective growth inhibitory effects in human colon HCT-116 and HT29 cancer cells through induction of apoptosis, cell cycle arrest and inhibition of cell migration. |
| PubMed:Multifunctional oxidosqualene cyclases and cytochrome P450 involved in the biosynthesis of apple fruit triterpenic acids. |
| PubMed:Cytotoxic biomonitored study of Euphorbia umbellata (Pax) Bruyns. |
| PubMed:Chemical Constituents of Lecythispisonis (Lecythidaceae)--A New Saponin and Complete 1H and 13C Chemical Shift Assignments. |
| PubMed:Phytochemical and pharmacological study of Ficus palmata growing in Saudi Arabia. |
| PubMed:Changes in the triterpenoid content of cuticular waxes during fruit ripening of eight grape (Vitis vinifera) cultivars grown in the Upper Rhine Valley. |
| PubMed:Klodorone A and klodorol A: new triterpenes from Kleinia odora. |
| PubMed:[Triterpene compounds of Ainsliaea yunnanensis]. |
| PubMed:Effect of cation-π interactions and steric bulk on the catalytic action of oxidosqualene cyclase: a case study of Phe728 of β-amyrin synthase from Euphorbia tirucalli L. |
| PubMed:[Chemical constituents of Psammosilene tunicoides and bacteriostatic activity]. |
| PubMed:Triterpenoid profile of flower and leaf cuticular waxes of heather Calluna vulgaris. |
| PubMed:Isolation and characterization of new ceramides from aerial parts of Lepidaploa cotoneaster. |
| PubMed:Source correlation of biomarkers in a mangrove ecosystem on Santa Catarina Island in southern Brazil. |
| PubMed:Synthesis and anti-HIV activity of lupane and olean-18-ene derivatives. Absolute configuration of 19,20-epoxylupanes by VCD. |
| PubMed:Antibacterial activity of the essential oils of Pistacia lentiscus used in Moroccan folkloric medicine. |
| PubMed:A new triterpene from Barringtonia asiatica. |
| PubMed:New triterpenes from Barringtonia asiatica. |
| PubMed:Antiinflammatory properties of Morus nigra leaves. |
| PubMed:Occurrence and sources of triterpenoid methyl ethers and acetates in sediments of the cross-river system, southeast Nigeria. |
| PubMed:Composition of the epicuticular and intracuticular wax layers on Kalanchoe daigremontiana (Hamet et Perr. de la Bathie) leaves. |
| PubMed:Development of the cuticular wax during growth of Kalanchoe daigremontiana (Hamet et Perr. de la Bathie) leaves. |
| PubMed:Rapid and enantioselective synthetic approaches to germanicol and other pentacyclic triterpenes. |
| PubMed:Triterpene synthases from the Okinawan mangrove tribe, Rhizophoraceae. |
| PubMed:Two new 18-en-oleane derivatives from marine mangrove plant, Barringtonia racemosa. |
| PubMed:Antitumor and antiinflammatory constituents from Celtis sinensis. |
| PubMed:Cytotoxic activity of moronic acid and identification of the new triterpene 3,4-seco-olean-18-ene-3,28-dioic acid from Phoradendron reichenbachianum. |
| PubMed:Arabidopsis thaliana LUP1 converts oxidosqualene to multiple triterpene alcohols and a triterpene diol. |
| PubMed:Koelpinin-A, B and C--three triterpenoids from Koelpinia linearis. |
| PubMed:Molluscicidal constituents of Marsypianthes chamaedrys. |
| PubMed:Triterpenoid compounds from Araujia sericifera B. Effects on the isolated guinea pig ileum. |
| PubMed:Antiplasmodial triterpene from Vernonia brasiliana. |
| PubMed:Linear, steroidal, and triterpene esters, and steryl glycosides from Festuca argentina. |
| PubMed:[Triterpene constituents from Euphorbia nematocypha Hand-Mazz]. |
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3D/inchi