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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 4.87 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for sesamolin usage levels up to: | | | not for fragrance use.
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| Recommendation for sesamolin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :101746 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| 5-[[(3S,3aR,6R,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]oxy]-1,3-benzodioxole |
| Chemidplus:0000526078 |
References:
| | 5-[[(3S,3aR,6R,6aR)-3-(1,3-benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]oxy]-1,3-benzodioxole |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 101746 |
| Pubchem (cas): | 526-07-8 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 5-[[(3S,3aR,6R,6aR)-3-(1,3- | benzodioxol-5-yl)-1,3,3a,4,6,6a-hexahydrofuro[3,4-c]furan-6-yl]oxy]-1,3-benzodioxole | | 1,3- | benzodioxole, 5-(4-(1,3-benzodioxol-5-yloxy)tetrahydro-1H,3H-furo(3,4-c)furan-1-yl)-, (1S-(1alpha,3a alpha,4alpha,6a alpha))- |
Articles:
| PubMed:Quality properties of puffed corn snacks incorporated with sesame seed powder. |
| PubMed:Oxidative rearrangement of (+)-sesamin by CYP92B14 co-generates twin dietary lignans in sesame. |
| PubMed:Encapsulation of sesamol in phosphatidyl choline micelles: Enhanced bioavailability and anti-inflammatory activity. |
| PubMed:Manufacture of low-benzo(a)pyrene sesame seed (Sesamum indicum L.) oil using a self-designed apparatus. |
| PubMed:A Nuclear Magnetic Resonance Spectroscopy Approach to Discriminate the Geographic Origin of Roasted Asian Sesame Oils. |
| PubMed:Determination and purification of sesamin and sesamolin in sesame seed oil unsaponified matter using reversed-phase liquid chromatography coupled with photodiode array and tandem mass spectrometry and high-speed countercurrent chromatography. |
| PubMed:Magnetic solid-phase extraction based on graphene oxide for the determination of lignans in sesame oil. |
| PubMed:Discovery of a sesamin-metabolizing microorganism and a new enzyme. |
| PubMed:Synthesis of furofuran lignans as antidiabetic agents simultaneously achieved by inhibiting α-glucosidase and free radical. |
| PubMed:Inhibition of lipoxygenase by sesamol corroborates its potential anti-inflammatory activity. |
| PubMed:Effects of Sesaminol Feeding on Brain Aβ Accumulation in a Senescence-Accelerated Mouse-Prone 8. |
| PubMed:Preparative separation of sesamin and sesamolin from defatted sesame meal via centrifugal partition chromatography with consecutive sample injection. |
| PubMed:Accelerated separation of GC-amenable lipid classes in plant oils by countercurrent chromatography in the co-current mode. |
| PubMed:Combined Analysis of Stable Isotope, (1)H NMR, and Fatty Acid To Verify Sesame Oil Authenticity. |
| PubMed:Sesamolin enhances NK cell lysis activity by increasing the expression of NKG2D ligands on Burkitt's lymphoma cells. |
| PubMed:Evaluation of plant growth regulatory activity of furofuran lignan bearing a 7,9':7',9-diepoxy structure using optically pure (+)- and (-)-enantiomers. |
| PubMed:Characterization of the Fluorescent Spectra and Intensities of Various Lignans: Application to HPLC Analysis with Fluorescent Detection†. |
| PubMed:Bioactive lignans from sesame (Sesamum indicum L.): evaluation of their antioxidant and antibacterial effects for food applications. |
| PubMed:Tracking sesamin synthase gene expression through seed maturity in wild and cultivated sesame species--a domestication footprint. |
| PubMed:Comparative effects of sesame seeds differing in lignan contents and composition on fatty acid oxidation in rat liver. |
| PubMed:The relationship of antioxidant components and antioxidant activity of sesame seed oil. |
| PubMed:Value addition in sesame: A perspective on bioactive components for enhancing utility and profitability. |
| PubMed:Sesamol suppresses cyclooxygenase-2 transcriptional activity in colon cancer cells and modifies intestinal polyp development in Apc (Min/+) mice. |
| PubMed:Sesame oil attenuates nutritional fibrosing steatohepatitis by modulating matrix metalloproteinases-2, 9 and PPAR-γ. |
| PubMed:Sesamin and sesamolin as unexpected contaminants in various cold-pressed plant oils: NP-HPLC/FLD/DAD and RP-UPLC-ESI/MS(n) study. |
| PubMed:Lignans of sesame: purification methods, biological activities and biosynthesis--a review. |
| PubMed:Sesamol treatment reduces plasma cholesterol and triacylglycerol levels in mouse models of acute and chronic hyperlipidemia. |
| PubMed:Penicillium sp. mitigates Fusarium-induced biotic stress in sesame plants. |
| PubMed:Tissue distribution and cytochrome P450 inhibition of sesaminol and its tetrahydrofuranoid metabolites. |
| PubMed:Prophylactic sesame oil attenuates sinusoidal obstruction syndrome by inhibiting matrix metalloproteinase-9 and oxidative stress. |
| PubMed:Therapeutic oral sesame oil is ineffectual against monocrotaline-induced sinusoidal obstruction syndrome in rats. |
| PubMed:Analysis of expression sequence tags from a full-length-enriched cDNA library of developing sesame seeds (Sesamum indicum). |
| PubMed:Sesamolinol glucoside, disaminyl ether, and other lignans from sesame seeds. |
| PubMed:[Nutritional value of sesame seeds]. |
| PubMed:Sesamin ameliorates oxidative stress and mortality in kainic acid-induced status epilepticus by inhibition of MAPK and COX-2 activation. |
| PubMed:Experimental antithrombotic effects of sesame seed whole grains and extracts. |
| PubMed:Mechanism of oil-pulling therapy - in vitro study. |
| PubMed:Identification of methanol-soluble compounds in sesame and evaluation of antioxidant potential of its lignans. |
| PubMed:Interaction of sesamol (3,4-methylenedioxyphenol) with tyrosinase and its effect on melanin synthesis. |
| PubMed:Estrogenic activities of sesame lignans and their metabolites on human breast cancer cells. |
| PubMed:Sesame seed lignans: potent physiological modulators and possible ingredients in functional foods & nutraceuticals. |
| PubMed:Applications of integrated data mining methods to exploring natural product space for acetylcholinesterase inhibitors. |
| PubMed:Assessing the neuroprotective effect of antioxidant food factors by application of lipid-derived dopamine modification adducts. |
| PubMed:Analysis of antioxidant activities in vegetable oils and fat soluble vitamins and biofactors by the PAO-SO method. |
| PubMed:Identification and characterization of sesaminol metabolites in the liver. |
| PubMed:Effect of infrared heating on the formation of sesamol and quality of defatted flours from Sesamum indicum L. |
| PubMed:Lipid metabolism and nutrigenomics - impact of sesame lignans on gene expression profiles and fatty acid oxidation in rat liver. |
| PubMed:Comparative study of sesame lignans (sesamin, episesamin and sesamolin) affecting gene expression profile and fatty acid oxidation in rat liver. |
| PubMed:Effects of a diet rich in sesame ( Sesamum indicum) pericarp on the expression of oestrogen receptor alpha and oestrogen receptor beta in rat prostate and uterus. |
| PubMed:Elimination and metabolism of sesamol, a bioactive compound in sesame oil, in rats. |
| PubMed:Comparison of atmospheric pressure chemical ionization and electrospray ionization mass spectrometry for the detection of lignans from sesame seeds. |
| PubMed:Bioavailability and tissue distribution of sesamol in rat. |
| PubMed:Sex differences in the inhibition of gamma-tocopherol metabolism by a single dose of dietary sesame oil in healthy subjects. |
| PubMed:HPTLC fingerprinting and quantification of lignans as markers in sesame oil and its polyherbal formulations. |
| PubMed:Comparative analysis of sesame lignans (sesamin and sesamolin) in affecting hepatic fatty acid metabolism in rats. |
| PubMed:Synergistic antimicrobial activities of phytoestrogens in crude extracts of two sesame species against some common pathogenic microorganisms. |
| PubMed:Neuroprotective effects of sesamin and sesamolin on gerbil brain in cerebral ischemia. |
| PubMed:Nondestructive determination of lignans and lignan glycosides in sesame seeds by near infrared reflectance spectroscopy. |
| PubMed:Oxidative toxicity in BV-2 microglia cells: sesamolin neuroprotection of H2O2 injury involving activation of p38 mitogen-activated protein kinase. |
| PubMed:Consumption of sesame oil muffins decreases the urinary excretion of gamma-tocopherol metabolites in humans. |
| PubMed:Sesamin inhibits lipopolysaccharide-induced cytokine production by suppression of p38 mitogen-activated protein kinase and nuclear factor-kappaB. |
| PubMed:Sesame lignans enhance antioxidant activity of vitamin E in lipid peroxidation systems. |
| PubMed:Dietary sesame oils inhibits iron-induced oxidative stress in rats [corrected]. |
| PubMed:Protective effects of sesamin and sesamolin on murine BV-2 microglia cell line under hypoxia. |
| PubMed:Free radical scavenging behavior of antioxidant compounds of sesame (sesamum indicum L.) in DPPH(*) system. |
| PubMed:Synthesis and antioxidant activity of oxygenated furofuran lignans. |
| PubMed:Comparative analysis of expressed sequence tags from Sesamum indicum and Arabidopsis thaliana developing seeds. |
| PubMed:Effect of sesame antioxidants on LPS-induced NO production by BV2 microglial cells. |
| PubMed:Protective effects of sesamin and sesamolin on hypoxic neuronal and PC12 cells. |
| PubMed:Effects of dietary sesame seeds on plasma tocopherol levels. |
| PubMed:Effect of sesame seeds rich in sesamin and sesamolin on fatty acid oxidation in rat liver. |
| PubMed:Sesamolin from sesame seed inhibits proliferation by inducing apoptosis in human lymphoid leukemia Molt 4B cells. |
| PubMed:Quinoline alkaloids from Acronychia laurifolia. |
| PubMed:Sesamolin inhibits lipid peroxidation in rat liver and kidney. |
| PubMed:Oxygen insertion in Sesamum indicum furanofuran lignans. Diastereoselective syntheses of enzyme substrate analogues. |
| PubMed:Changes of ingredients in the process of cooking of sesame oil. |
| PubMed:Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acid biosynthesis. |
| PubMed:Is sesamol present in sesame oil? |
| PubMed:Contact sensitivity to unsaponifiable substances in sesame oil. |
| PubMed:Allergens in sesame oil contact dermatitis. |
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3D/inchi