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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 4.365 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for cyclobrassinin usage levels up to: | | | not for fragrance use.
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| Recommendation for cyclobrassinin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2- | methylsulfanyl-4,9-dihydro-[1,3]thiazino[6,5-b]indole | | 1,3- | thiazino(6,5-b)indole, 4,9-dihydro-2-(methylthio)- |
Articles:
| PubMed:Two cytochromes P450 catalyze S-heterocyclizations in cabbage phytoalexin biosynthesis. |
| PubMed:Tenualexin, other phytoalexins and indole glucosinolates from wild cruciferous species. |
| PubMed:The phytoalexins brassilexin and camalexin inhibit cyclobrassinin hydrolase, a unique enzyme from the fungal pathogen Alternaria brassicicola. |
| PubMed:The synthesis and anticancer activity of analogs of the indole phytoalexins brassinin, 1-methoxyspirobrassinol methyl ether and cyclobrassinin. |
| PubMed:Unprecedented spirocyclization of 3-methyleneindoline-2-thiones during hydrolysis of the phytoalexin cyclobrassinin. |
| PubMed:Detoxification of cruciferous phytoalexins in Botrytis cinerea: spontaneous dimerization of a camalexin metabolite. |
| PubMed:Impact of cruciferous phytoalexins on the detoxification of brassilexin by the blackleg fungus pathogenic to brown mustard. |
| PubMed:Substrate specificity and inhibition of brassinin hydrolases, detoxifying enzymes from the plant pathogens Leptosphaeria maculans and Alternaria brassicicola. |
| PubMed:Cloning, purification and characterisation of brassinin glucosyltransferase, a phytoalexin-detoxifying enzyme from the plant pathogen Sclerotinia sclerotiorum. |
| PubMed:Brassinin oxidase, a fungal detoxifying enzyme to overcome a plant defense -- purification, characterization and inhibition. |
| PubMed:Remarkable incorporation of the first sulfur containing indole derivative: another piece in the biosynthetic puzzle of crucifer phytoalexins. |
| PubMed:Phytoalexins and polar metabolites from the oilseeds canola and rapeseed: differential metabolic responses to the biotroph Albugo candida and to abiotic stress. |
| PubMed:Detection, characterization and identification of crucifer phytoalexins using high-performance liquid chromatography with diode array detection and electrospray ionization mass spectrometry. |
| PubMed:Detoxification of the cruciferous phytoalexin brassinin in Sclerotinia sclerotiorum requires an inducible glucosyltransferase. |
| PubMed:Phytoalexins from the crucifer rutabaga: structures, syntheses, biosyntheses, and antifungal activity. |
| PubMed:Antiproliferative and cancer chemopreventive activity of phytoalexins: focus on indole phytoalexins from crucifers. |
| PubMed:Chemical defenses of crucifers: elicitation and metabolism of phytoalexins and indole-3-acetonitrile in brown mustard and turnip. |
| PubMed:Strategies of cruciferous pathogenic fungi: detoxification of the phytoalexin cyclobrassinin by mimicry. |
| PubMed:The cruciferous phytoalexins brassinin and cyclobrassinin are intermediates in the biosynthesis of brassilexin. |
| PubMed:Cancer chemopreventive activity of brassinin, a phytoalexin from cabbage. |
| PubMed:Structure-activity relationships of brassinin in preventing the development of carcinogen-induced mammary lesions in organ culture. |
| PubMed:Growth inhibitions on human cancer cell cultures with the indole sulphur-containing phytoalexins and their analogues. |
| PubMed:Abiotic elicitation of indole phytoalexins and resistance to Leptosphaeria maculans within Brassiceae. |
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3D/inchi