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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 4.015 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for isogentisin usage levels up to: | | | not for fragrance use.
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| Recommendation for isogentisin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1,3- | dihydroxy-7-methoxyxanthen-9-one |
Articles:
| PubMed:Phytochemical analysis and antibacterial activity of Gentiana macrophylla extract against bacteria isolated from burn wound infections. |
| PubMed:Chromatographic Evaluation and Characterization of Components of Gentian Root Extract Used as Food Additives. |
| PubMed:Comparative HPLC/ESI-MS and HPLC/DAD study of different populations of cultivated, wild and commercial Gentiana lutea L. |
| PubMed:Induction of apoptosis in human pancreatic MiaPaCa-2 cells through the loss of mitochondrial membrane potential (ΔΨm) by Gentiana kurroo root extract and LC-ESI-MS analysis of its principal constituents. |
| PubMed:Chemical profile, radical scavenging and cytotoxic activity of yellow gentian leaves (Genitaneae luteaefolium) grown in northern regions of Montenegro. |
| PubMed:Antihyperalgesic activity of the methanol extract and some constituents obtained from Polygala cyparissias (Polygalaceae). |
| PubMed:Antiulcerogenic activity of extract, fractions, and some compounds obtained from Polygala cyparissias St. Hillaire & Moquin (Polygalaceae). |
| PubMed:Antimicrobial activity of Gentiana lutea L. extracts. |
| PubMed:Determination of gentisin, isogentisin, and amarogentin in Gentiana lutea L. by capillary electrophoresis. |
| PubMed:Quantitative analysis of iridoids, secoiridoids, xanthones and xanthone glycosides in Gentiana lutea L. roots by RP-HPLC and LC-MS. |
| PubMed:Isogentisin--a novel compound for the prevention of smoking-caused endothelial injury. |
| PubMed:Mutagenicities of xanthone derivatives in Salmonella typhimurium TA100, TA98, TA97, and TA2637. |
| PubMed:Mutagenic activities of gentisin and isogentisin from Gentianae radix (Gentianaceae). |
| PubMed:Inhibition of type A and type B monoamine oxidase by isogentisin and its 3-O-glucoside. |
| PubMed:Inhibition of monoamine oxidase by isogentisin and its 3-O-glucoside. |
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