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echinacin
apigenin-7-O-(6''-O-4-coumaroyl)-beta-glucopyranoside

Supplier Sponsors

Name:	[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate
CAS Number:	105815-90-5	3D/inchi
FDA UNII:	J64J7O64HY
Nikkaji Web:	J166.105A
XlogP3-AA:	2.60 (est)
Molecular Weight:	578.52762000
Formula:	C30 H26 O12
NMR Predictor:	Predict (works with chrome, Edge or firefox)
CAS Number:	8001-18-1	3D/inchi
FDA UNII:	Search

Category:moisturising agents

US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:

Google Scholar:	Search
Google Books:	Search
Google Scholar: with word "volatile"	Search
Google Scholar: with word "flavor"	Search
Google Scholar: with word "odor"	Search
Google Patents:	Search
US Patents:	Search
EU Patents:	Search
Pubchem Patents:	Search
PubMed:	Search
NCBI:	Search

Physical Properties:

Assay:	95.00 to 100.00
Food Chemicals Codex Listed:	No
Soluble in:
	water, 1.797 mg/L @ 25 °C (est)

Organoleptic Properties:

Odor and/or flavor descriptions from others (if found).

Cosmetic Information:

CosIng:	cosmetic data
Cosmetic Uses:	moisturising agents

Suppliers:

None found

Safety Information:


Hazards identification

Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements

Pictogram

Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined

Safety in Use Information:

Category:
moisturising agents
Recommendation for echinacin usage levels up to:
	not for fragrance use.

Recommendation for echinacin flavor usage levels up to:
	not for flavor use.

Safety References:

EPI System: View

AIDS Citations:Search

Cancer Citations:Search

Toxicology Citations:Search

EPA ACToR:Toxicology Data

EPA Substance Registry Services (SRS):Registry

Laboratory Chemical Safety Summary :6439941

National Institute of Allergy and Infectious Diseases:Data

[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate

Chemidplus:0105815905

Chemidplus:0008001181

References:

	[(2R,3S,4S,5R,6S)-3,4,5-trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate
NIST Chemistry WebBook:	Search Inchi
Pubchem (cid):	6439941
Pubchem (sid):	135103504
Pubchem (sid):	135316682

Other Information:

(IUPAC):	Atomic Weights of the Elements 2011 (pdf)
Videos:	The Periodic Table of Videos
tgsc:	Atomic Weights use for this web site
(IUPAC):	Periodic Table of the Elements
CHEMBL:	View
HMDB (The Human Metabolome Database):	Search
VCF-Online:	VCF Volatile Compounds in Food
ChemSpider:	View
Wikipedia:	View

Potential Blenders and core components note

None Found

Potential Uses:

None Found

Occurrence (nature, food, other):note

found in nature

Synonyms:

	apigenin-7-O-(6''-O-4-coumaroyl)-beta-glucopyranoside
4H-1-	benzopyran-4-one, 5-hydroxy-2-(4-hydroxyphenyl)-7-[[6-O-[(2E)-3-(4-hydroxyphenyl)-1-oxo-2-propenyl]-beta-D-glucopyranosyl]oxy]-
	echinacina B
[(2R,3S,4S,5R,6S)-3,4,5-	trihydroxy-6-[5-hydroxy-2-(4-hydroxyphenyl)-4-oxochromen-7-yl]oxyoxan-2-yl]methyl (E)-3-(4-hydroxyphenyl)prop-2-enoate

Articles:

PubMed:Anti-aromatase activity of the constituents from damiana (Turnera diffusa).

PubMed:Evaluation of echinacea for the prevention and treatment of the common cold: a meta-analysis.

PubMed:[Effectiveness of echinacin in therapy of chronic recurrent respiratory disease].

PubMed:Efficacy of Echinacea purpurea in patients with a common cold. A placebo-controlled, randomised, double-blind clinical trial.

PubMed:Benefit-risk assessment of the squeezed sap of the purple coneflower (Echinacea purpurea) for long-term oral immunostimulation.

PubMed:[Clinical application of extracts of Echinacea purpurea or Echinacea pallida. Critical evaluation of controlled clinical studies].

PubMed:[Echinacea drugs--effects and active ingredients].

PubMed:Results of five randomized studies on the immunomodulatory activity of preparations of Echinacea.

PubMed:Effects of non-specific immunostimulants (echinacin, isoprinosine and thymus factors) on the infection and antigen expression in herpesvirus-6 exposed human lymphoid cells.

PubMed:[Immunostimulation].

PubMed:[Chemoimmunotherapy of malignancies of the gastrointestinal tract].

PubMed:[Effect of supposed radioprotectors on oxidation-reduction of vitamin E in the tissues of irradiated rats].

PubMed:Nonspecific immunostimulation with low doses of cyclophosphamide (LDCY), thymostimulin, and Echinacea purpurea extracts (echinacin) in patients with far advanced colorectal cancers: preliminary results.

PubMed:[The effect of Echinacea purpurea Moench on phagocytosis in granulocytes measured by chemiluminescence].

PubMed:Stimulation of the immune response in outpatients with hepatocellular carcinomas by low doses of cyclophosphamide (LDCY), echinacea purpurea extracts (Echinacin) and thymostimulin.

PubMed:[Determination of the activity of extracts of Echinaceae and Sabal in the treatment of idiopathic megabladder in women].

PubMed:Immunomodulation with Viscum album and Echinacea purpurea extracts.

PubMed:[Experimental studies on the action of extracts of herba recens Echinaceae purpureae on skin flaps].

PubMed:Evidence from two classic irritation tests for an anti-inflammatory action of a natural extract, Echinacina B.

PubMed:[Effect of Echinacin on phagocytosis and natural killer cells].

PubMed:[Clinical and laboratory assessment of the therapeutic activity of the drug Echinacin-extern in mixed periodontopathies].

PubMed:[Non-specific increase of the body's own immunity by Echinacin administration].

PubMed:[Echinacin externa use in the treatment of periodontopathies].

PubMed:[Echinacin in primary chronic polyarthritis therapy].

PubMed:[Echinacin test for the provocation of leukocytes in effective radiotherapy].

PubMed:[Therapy of whooping cough with Myo-echinacin].

PubMed:[Directed control of leukocyte kinetics by Echinacin].

PubMed:[Pediatric experiences with myo-echinacin].

PubMed:[PERTUSSIS THERAPY WITH MYO-ECHINACIN IN PEDIATRIC PRACTICE].

PubMed:[DECREASE OF LEUKOCYTE RESISTANCE BY CHLORONITRINE AND ITS PREVENTION BY ECHINACIN].

PubMed:[Echinacin therapy in gynecology].

PubMed:[The significance of echinacin in tuberculosis therapy].

PubMed:[Successful influenza therapy with myo-echinacin].

PubMed:[Experience with an additional therapy of psoriasis vulgaris with echinacin].

PubMed:[Experience with the therapy of Sudeck's syndrome with echinacin].

PubMed:[Experimental studies on cortisone and echinacin on local tissue resistance to streptococcal infections].

PubMed:[Effect of hyaluronidase and hyaluronidase inhibitor (echinacin) on trypanocidal effect of salvarsan].

PubMed:[Early treatment of puerperal mastitis with echinacin].

PubMed:[Echinacin and phagocyte reaction].

PubMed:[Therapy of chronic adnexitis with echinacin].

PubMed:[Experiences with the Echinacin therapy of pelvic inflammatory diseases].

Notes:

None found

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