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Category:pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est)
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| Soluble in: |
| | water, 3520 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 164 mg/kg
BEHAVIORAL: EXCITEMENT
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. Vol. (103), Pg. 29, 1985.
intravenous-mouse LD50 200 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 90, Pg. 18, 1952.
oral-mouse LD50 2400 mg/kg
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM SMALL INTESTINE
Eisei Shikenjo Hokoku. Bulletin of the Institute of Hygienic Sciences. Vol. (103), Pg. 29, 1985.
intravenous-rabbit LDLo 50 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Zeitschrift fuer die Gesamte Experimentelle Medizin. Vol. 52, Pg. 779, 1926.
oral-rat LDLo 713 mg/kg
VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION
CARDIAC: EKG CHANGES NOT DIAGNOSTIC OF ABOVE
BEHAVIORAL: COMA
Journal of the Formosan Medical Association. Vol. 91, Pg. 743, 1992.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | pharmaceuticals / chemical synthisis |
| Recommendation for sodium cholate usage levels up to: | | | not for fragrance use.
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| Recommendation for sodium cholate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | cholan-24-oic acid, 3,7,12-trihydroxy-, monosodium salt, (3-alpha,5-beta,7-alpha,12-alpha)- | | | cholan-24-oic acid, 3,7,12-trihydroxy-, monosodium salt, (3alpha,5beta,7alpha,12alpha)- | | | cholan-24-oic acid, 3,7,12-trihydroxy-, sodium salt (1:1), (3alpha,5beta,7alpha,12alpha)- | | | cholic acid, monosodium salt | | | cholic acid, sodium salt | | | sodium cholic acid | | | trihydroxy 3-7-12 cholanate de Na |
Articles:
| PubMed:Fluorescence method using on-line sodium cholate coacervate surfactant mediated extraction for the flow injections analysis of Rhodamine B. |
| PubMed:Effect of nanostructured lipid vehicles on percutaneous absorption of curcumin. |
| PubMed:Study on interaction of bile salts with curcumin and curcumin embedded in dipalmitoyl-sn-glycero-3-phosphocholine liposome. |
| PubMed:Enzymatic synthesis of phosphatidylserine using bile salt mixed micelles. |
| PubMed:[Analysis of phthalate esters in plastic-packaging bags on-line sample stacking-microemulsion electrokinetic chromatography]. |
| PubMed:Label-free aptamer-based partial filling technique for enantioseparation and determination of DL-tryptophan with micellar electrokinetic chromatography. |
| PubMed:Effect of prolonged refrigeration on the lipid profile, lipase activity, and oxidative status of human milk. |
| PubMed:In vitro hypoglycemic and cholesterol lowering effects of dietary fiber prepared from cocoa (Theobroma cacao L.) shells. |
| PubMed:Fish protein decreases serum cholesterol in rats by inhibition of cholesterol and bile acid absorption. |
| PubMed:Fish protein hydrolysates affect cholesterol metabolism in rats fed non-cholesterol and high-cholesterol diets. |
| PubMed:In vitro binding capacity of bile acids by defatted corn protein hydrolysate. |
| PubMed:In vitro binding capacities of three dietary fibers and their mixture for four toxic elements, cholesterol, and bile acid. |
| PubMed:Determination of phthalate esters in soil by microemulsion electrokinetic chromatography coupled with accelerated solvent extraction. |
| PubMed:Determination of aromatic amines in environmental water sample by hollow fiber-liquid phase microextraction and microemulsion electrokinetic chromatography. |
| PubMed:Probiotic properties of yeasts isolated from chicken feces and kefirs. |
| PubMed:Effects of rice proteins from two cultivars, Koshihikari and Shunyo, on hepatic cholesterol secretion by isolated perfused livers of rats fed cholesterol-enriched diets. |
| PubMed:Blood lipid-lowering and antioxidant effects of a structured lipid containing monoacylglyceride enriched with monounsaturated fatty acids in C57BL/6 mice. |
| PubMed:Separation and detection of isoquinoline alkaloids using MEEKC coupled with field-amplified sample injection induced by ACN. |
| PubMed:A new mixed micellar electrokinetic chromatography method for analysis of natural and synthetic anabolic steroids. |
| PubMed:Effects of cranberry powder on serum lipid profiles and biomarkers of oxidative stress in rats fed an atherogenic diet. |
| PubMed:Microemulsion electrokinetic chromatography coupling with field amplified sample injection and electroosmotic flow suppressant for analysis of some quinolizidine alkaloids. |
| PubMed:Separation and determination of flavonoids using microemulsion EKC with electrochemical detection. |
| PubMed:Determination of flavonoid aglycones in several food samples by mixed micellar electrokinetic chromatography. |
| PubMed:Nonaqueous and aqueous-organic media for the enantiomeric separations of neutral organophosphorus pesticides by CE. |
| PubMed:Evaluation of inactivation methods for severe acute respiratory syndrome coronavirus in noncellular blood products. |
| PubMed:Dietary lectin lowers serum cholesterol and raises fecal neutral sterols in cholesterol-fed rats. |
| PubMed:Functional properties, lipoxygenase activity, and health aspects of Lupinus albus protein isolates. |
| PubMed:Effect of the adaptation to high bile salts concentrations on glycosidic activity, survival at low PH and cross-resistance to bile salts in Bifidobacterium. |
| PubMed:The effect of taurine on cholesterol degradation in mice fed a high-cholesterol diet. |
| PubMed:The effect of taurine on the cholesterol metabolism in rats fed diets supplemented with cholestyramine or high amounts of bile acid. |
| PubMed:The effect of taurine on plasma cholesterol concentration in genetic type 2 diabetic GK rats. |
| PubMed:Mixed micellar electrokinetic capillary chromatography separation of depolymerized grape procyanidins. |
| PubMed:Characterisation of a Bifidobacterium strain with acquired resistance to cholate--a preliminary study. |
| PubMed:Hypocholesterolemic effect of indigestible fraction of Chlorella regularis in cholesterol-fed rats. |
| PubMed:Determination of total cholesterol content in food by flow injection analysis with immobilized cholesterol oxidase enzyme reactor. |
| PubMed:Effects of dietary maritime pine seed oil on lipoprotein metabolism and atherosclerosis development in mice expressing human apolipoprotein B. |
| PubMed:A double antibody sandwich enzyme-linked immunosorbent assay for the detection of Salmonella using biotinylated monoclonal antibodies. |
| PubMed:Cholesterol solubilization in aqueous micellar solutions of quillaja saponin, bile salts, or nonionic surfactants. |
| PubMed:Separation of food grade antioxidants (synthetic and natural) using mixed micellar electrokinetic capillary chromatography. |
| PubMed:A mixture of organisms affects cholesterol metabolism together with rat cecal flora. |
| PubMed:Simultaneous determination of antioxidants, preservatives and sweeteners permitted as additives in food by mixed micellar electrokinetic chromatography. |
| PubMed:Determination of vitamins in food based on supercritical fluid extraction prior to micellar electrokinetic capillary chromatographic analyses of individual vitamins. |
| PubMed:Occurrence of dermatitis in rats fed a cholesterol diet containing field horsetail (Equisetum arvense L.). |
| PubMed:Strain-specific response to hypercholesterolaemic diets in the rat. |
| PubMed:The effects of pH and bile salts on the binding of MeIQx to wheat bran fibre. |
| PubMed:Analysis of macrolide antibiotics by capillary electrophoresis. |
| PubMed:Simultaneous dietary supplementation of sodium cholate and beta-carotene markedly enhances accumulation of beta-carotene in mice. |
| PubMed:In vivo regulation of hepatic lipase activity and mRNA levels by diets which modify cholesterol influx to the liver. |
| PubMed:Relationship between structure and function of dietary fibre: a comparative study of the effects of three galactomannans on cholesterol metabolism in the rat. |
| PubMed:Synthetic low and high fat diets for the study of atherosclerosis in the mouse. |
| PubMed:Purification and characterization of phosphatidate phosphatase from Saccharomyces cerevisiae. |
| PubMed:Effect of dietary taurine on cholesterol 7 alpha-hydroxylase activity in the liver of mice fed a lithogenic diet. |
| PubMed:A mechanism for the hypocholesterolaemic activity of saponins. |
| PubMed:Enzymatic properties of the lipoxygenase from pea seeds. |
| PubMed:Bile production in fasted and fed primates. |
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3D/inchi