| Name: | methyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride |
| CAS Number: | 66634-44-4 |  3D/inchi
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| ECHA EINECS - REACH Pre-Reg: | 266-430-8 |
| FDA UNII: | Search |
| MDL: | MFCD00064554 |
| Molecular Weight: | 390.90979000 |
| Formula: | C21 H27 Cl N2 O3 |
| BioActivity Summary: | listing |
| NMR Predictor: | Predict (works with chrome, Edge or firefox) |
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est)
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Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-guinea pig LD50 158 mg/kg
BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Comptes Rendus des Seances de la Societe de Biologie et de Ses Filiales. Vol. 146, Pg. 1042, 1952.
intravenous-mouse LDLo 75 mg/kg
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 50, Pg. 241, 1935.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for rauhimbine usage levels up to: | | | not for fragrance use.
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| Recommendation for rauhimbine flavor usage levels up to: |
| | not for flavor use.
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Safety References:
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :198500 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| methyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride |
| Chemidplus:0066634444 |
| RTECS:ZG1025000 for cas# 66634-44-4 |
References:
| | methyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 198500 |
| Pubchem (sid): | 135175657 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | chlorhydrate de corynanthine | | | corynanthine hydrochloride | | 17alpha- | hydroxyyohimban-16beta-carboxylic acid methyl ester | | | methyl (1S,15R,18S,19S,20S)-18-hydroxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;hydrochloride | | | yohimban-16-beta-carboxylic acid, 17-alpha-hydroxy-, methyl ester, hydrochloride | | | yohimbine hydrochloride |
Articles:
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