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 Category:surfactant 
  
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: 
  
Physical Properties: 
| Assay: |  95.00 to 100.00 
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| Food Chemicals Codex Listed:  | No |  
 
  
Organoleptic Properties: 
| Odor and/or flavor descriptions from others (if found). |  
 
  
Cosmetic Information: 
  
Suppliers: 
  
Safety Information: 
|   |  
| Hazards identification |  
|   |  
|  Classification of the substance or mixture |  
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |  
| None found. |  
|  GHS Label elements, including precautionary statements |  
|   |  
| Pictogram |  |  
|   |  
                                                                     
| Hazard statement(s) |  
| None found. |  
| Precautionary statement(s) |  
| None found. |  
| Oral/Parenteral Toxicity:  |  
intravenous-guinea pig LD50  38 mg/kg BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
KIDNEY, URETER, AND BLADDER: HEMATURIA
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957.
  
oral-guinea pig LD50  384 mg/kg PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957.
  
intraperitoneal-mouse LD50  160 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.
  
intraperitoneal-mouse LD50  160 mg/kg Drugs in Japan Vol. -, Pg. 1300, 1995.
  
intravenous-mouse LD50  100 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.
  
intravenous-mouse LD50  100 mg/kg Toxicology and Applied Pharmacology. Vol. 7, Pg. 206, 1965.
  
oral-mouse LD50  1170 mg/kg Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960.
  
oral-mouse LD50  1170 mg/kg PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE)
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY)
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957.
  
oral-mouse LD50  3500 mg/kg American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962.
  
oral-mouse LD50  4940 mg/kg American Perfumer and Cosmetics. Vol. 77, Pg. 35, 1962.
  
intratracheal-rabbit LD50  > 15 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976.
  
intravenous-rabbit LD50  36 mg/kg KIDNEY, URETER, AND BLADDER: HEMATURIA
LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES
BEHAVIORAL: CHANGES IN MOTOR ACTIVITY (SPECIFIC ASSAY) Arzneimittel-Forschung. Drug Research. Vol. 7, Pg. 162, 1957.
  
parenteral-rabbit LD50  > 75 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 78, 1976.
  
intraperitoneal-rat LD50  125 mg/kg GASTROINTESTINAL: OTHER CHANGES Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970.
  
intravenous-rat LD50  27 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.
  
intravenous-rat LD50  27 mg/kg Drugs in Japan Vol. -, Pg. 1300, 1995.
  
intravenous-rat LD50  390 mg/kg Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960.
  
oral-rat LD50  1000 mg/kg LIVER: FATTY LIVER DEGERATION
GASTROINTESTINAL: OTHER CHANGES
GASTROINTESTINAL: ULCERATION OR BLEEDING FROM STOMACH Food and Cosmetics Toxicology. Vol. 8, Pg. 125, 1970.
  
oral-rat LD50  4150 mg/kg Toxicology and Applied Pharmacology. Vol. 2, Pg. 133, 1960.
  
oral-rat LD50  8600 mg/kg Soap, Perfumery & Cosmetics. Vol. 38, Pg. 47, 1965.
  
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| Dermal Toxicity:  |  
subcutaneous-mouse LD50 792 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.
  
subcutaneous-mouse LD50 792300 ug/kg Drugs in Japan Vol. -, Pg. 1300, 1995.
  
subcutaneous-rat LD50 953 mg/kg Drugs in Japan Vol. -, Pg. 1300, 1995.
  
subcutaneous-rat LD50 954 mg/kg Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 22, Pg. 967, 1991.
  
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| Inhalation Toxicity:  |  
| 
Not determined
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Safety in Use Information: 
| Category:  |  | surfactant |  
| Recommendation for laureth-21 usage levels up to:  |  |   | not for fragrance use.
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|   |  
| Recommendation for laureth-21 flavor usage levels up to:  |  
|   | not for flavor use.
 |  
 
  
Safety References: 
  
References: 
  
Other Information: 
  
Potential Blenders and core components  note 
  
Potential Uses: 
  
Occurrence (nature, food, other): note 
  
Synonyms: 
| 2- | dodecoxyethanol (peg-21) |  |   | nikkol BL-21 |  |   | peg-21 lauryl ether |  |   | poly(oxy-1,2-ethanediyl), .alpha.-dodecyl-.omega.-hydroxy- (21 mol EO average molar ratio) |  |   | polyethylene glycol (21) lauryl ether |  |   | polyethylene glycol (21) monolauryl ether |  |   | polyoxyethylene (21) lauryl ether |  |   | polyoxyethylene (21) monolauryl ether |  
 
  
Articles:
  
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