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Category:oral care agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est)
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Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | oral care agents |
| Recommendation for copper picolinate usage levels up to: | | | not for fragrance use.
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| Recommendation for copper picolinate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | copper;pyridine-2-carboxylate | | | copper(2+) di(2-pyridinecarboxylate) | | | copper(2+) dipyridine-2-carboxylate | | | copper(II) picolinate | | | copperpicolinate | | 2- | pyridinecarboxylic acid, copper complex dihydrate | | 2- | pyridinecarboxylic acid, copper(2+) salt (2:1) |
Articles:
| PubMed:Monopicolinate Cross-Bridged Cyclam Combining Very Fast Complexation with Very High Stability and Inertness of Its Copper(II) Complex. |
| PubMed:Picolinic acid based Cu(II) complexes with heterocyclic bases - Crystal structure, DNA binding and cleavage studies. |
| PubMed:Enantiomeric in vitro DNA binding, pBR322 DNA cleavage and molecular docking studies of chiral L- and D-ternary copper(II) complexes of histidine and picolinic acid. |
| PubMed:Synthesis of cyclobakuchiols A, B, and C by using conformation-controlled stereoselective reactions. |
| PubMed:Monopicolinate-dipicolyl derivative of triazacyclononane for stable complexation of Cu2+ and 64Cu2+. |
| PubMed:Monopicolinate cyclen and cyclam derivatives for stable copper(II) complexation. |
| PubMed:Cu(I)-catalyzed annulation for the synthesis of substituted naphthalenes using o-bromobenzaldehydes and β-ketoesters as substrates. |
| PubMed:Evaluation of the binding of oxovanadium(IV) to human serum albumin. |
| PubMed:[Copper compounds ameliorate cardiovasclur dysfunction and diabetes in animals]. |
| PubMed:Chemoselectivity in the Cu-catalyzed O-arylation of phenols and aliphatic alcohols. |
| PubMed:Diaqua-(6-bromo-picolinato-κN,O)(nitrato-κO,O)copper(II). |
| PubMed:Cu-catalyzed arylation of phenols: synthesis of sterically hindered and heteroaryl diaryl ethers. |
| PubMed:Orthogonal Cu- and Pd-based catalyst systems for the O- and N-arylation of aminophenols. |
| PubMed:Formation of chiral C(sp3)-C(sp) bond by allylic substitution of secondary allylic picolinates and alkynyl copper reagents. |
| PubMed:Stability, water exchange, and anion binding studies on lanthanide(III) complexes with a macrocyclic ligand based on 1,7-diaza-12-crown-4: extremely fast water exchange on the Gd3+ complex. |
| PubMed:(Acetato-kappaO)aqua(1H-imidazole-kappaN3)(picolinato-kappa2N,O)copper(II) 0.87-hydrate: a Z' > 1 structure. |
| PubMed:Metal complexes of a picolinate-based nitronyl nitroxide free radical. |
| PubMed:Separation of transition metals on a poly-iminodiacetic acid grafted polymeric resin column with post-column reaction detection utilising a paired emitter-detector diode system. |
| PubMed:A mononuclear and a mixed-valence chain polymer arising from copper(II) halide chemistry and the use of 2,2'-pyridil. |
| PubMed:[6-(3,5-Dimethyl-1H-pyrazol-1-yl)picolinato](pyridine-2,6-dicarboxyl-ato)copper(II) dihydrate. |
| PubMed:Bis[3-chloro-6-(3,5-dimethyl-1H-pyrazol-1-yl)picolinato-κO,N,N']copper(II) tetra-hydrate. |
| PubMed:Room-temperature copper-catalyzed alpha-arylation of malonates. |
| PubMed:Unusual oxidation of an N-heterocycle ligand in a metal-organic framework. |
| PubMed:Antidiabetic copper(II)-picolinate: impact of the first transition metal in the metallopicolinate complexes. |
| PubMed:An orthogonal ferromagnetically coupled tetracopper(II) 2 x 2 homoleptic grid supported by micro-O4 bridges and its DFT study. |
| PubMed:[Synthesis and spectral analysis of metal-N-glycoside complexes and studies of catalyzed ester hydrolytic kinetics]. |
| PubMed:Hydrolysis of p-nitrophenyl picolinate catalyzed by metal complexes of N-alkyl-3,5-bis(hydroxymethyl)-1,2,4-triazole in CTAB micelles. |
| PubMed:trans-Diaquabis(6-hydroxypicolinato-kappa2N,O2)copper(II). |
| PubMed:Effects of supplemental copper and chromium on the serum and egg traits of laying hens. |
| PubMed:Direct determination of copper in urine using a sol-gel optical sensor coupled to a multicommutated flow system. |
| PubMed:Dipicolinic acid prevents the copper-dependent oxidation of low density lipoprotein. |
| PubMed:A cofactor approach to copper-dependent catalytic antibodies. |
| PubMed:Metallomicellar Catalysis Hydrolysis of p-Nitrophenyl Picolinate Catalyzed by Copper(II), Nickel(II), and Zinc(II) Complexes of Long Alkyl Pyridine Ligands in Micellar Solution. |
| PubMed:Beneficial effects of chromium on glucose and lipid variables in control and somatotropin-treated pigs are associated with increased tissue chromium and altered tissue copper, iron, and zinc. |
| PubMed:Chromium supplementation and resistance training: effects on body composition, strength, and trace element status of men. |
| PubMed:Complexometric titrations of protein-bound metal ions: a method for determining binding constants. |
| PubMed:Uptake of copper from brass vessels by bovine milk and its relevance to Indian childhood cirrhosis. |
| PubMed:Influence of dietary picolinic acid on mineral metabolism in the rat. |
| PubMed:Effects of the interrelationship between dietary protein and minerals on tissue content of trace metals in streptozotocin-diabetic rats. |
| PubMed:[Substituted picolinic acids as DBH inhibitors. Inhibition of dopamine beta-hydroxylase and antihypertensive action]. |
| PubMed:Metal-binding ligands in Viokase. |
| PubMed:In vitro competition between calcium phytate and the soluble fraction of rat small intestine contents for cadmium, copper and zinc. |
| PubMed:Copper bioavailability and requirements. |
| PubMed:Detection of low molecular weight copper(II) and zinc(II) binding ligands in ultrafiltered milks-the citrate connection. |
| PubMed:Zinc absorption in the rat. |
| PubMed:Spectrophotometric determination of vanadium after extraction as vanadium(III) picolinate. |
| PubMed:HYDROLYSIS OF PROTOLYTIC ESTERS. 3. COPPER-CATALYZED HYDROLYSIS OF ETHYL PICOLINATE. |
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