|
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Boiling Point: | 528.80 °C. @ 760.00 mm Hg (est)
|
| Flash Point: | 423.00 °F. TCC ( 217.00 °C. ) (est)
|
| logP (o/w): | 10.300 (est) |
| Soluble in: |
| | water, 1.929e-006 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
|
Not determined
|
| Dermal Toxicity: |
|
Not determined
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for beta-tocotrienol usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for beta-tocotrienol flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
European Food Safety Authority (EFSA) reference(s):
|
Scientific Opinion on the re-evaluation of tocopherol-rich extract (E 306), a-tocopherol (E 307), ?-tocopherol (E 308) and d-tocopherol (E 309) as food additives
View page or View pdf
|
| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):490-23-3 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :5282348 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:2 |
| (2R)-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl]-3,4-dihydrochromen-6-ol |
| Chemidplus:0000490233 |
References:
| | (2R)-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl]-3,4-dihydrochromen-6-ol |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 5282348 |
| Pubchem (sid): | 135052133 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 2H-1- | benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-((3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl)-, (2R)- | | 2H-1- | benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-, [R-(E,E)]- | | 2H-1- | benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrien-1-yl]-, (2R)- | | 2H-1- | benzopyran-6-ol, 3,4-dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-, (2R)- | | (2R)-3,4- | dihydro-2,5,8-trimethyl-2-[(3E,7E)-4,8,12-trimethyl-3,7,11-tridecatrienyl]-2H-1-benzopyran-6-ol | | e- | tocopherol | | epsilon- | tocopherol | | b- | tocotrienol | | D-b- | tocotrienol | | e- | tokoferol | | (2R)-2,5,8- | trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]-3,4-dihydro-2H-chromen-6-ol | | (2R)-2,5,8- | trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trien-1-yl]chroman-6-ol | | (2R)-2,5,8- | trimethyl-2-[(3E,7E)-4,8,12-trimethyltrideca-3,7,11-trienyl]-3,4-dihydrochromen-6-ol |
Articles:
| PubMed:Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophersolan. |
| PubMed:Antioxidant activities of tocopherols/tocotrienols and lipophilic antioxidant capacity of wheat, vegetable oils, milk and milk cream by using photochemiluminescence. |
| PubMed:Antiproliferation and induction of caspase-8-dependent mitochondria-mediated apoptosis by β-tocotrienol in human lung and brain cancer cell lines. |
| PubMed:Tocochromanols and carotenoids in sorghum (Sorghum bicolor L.): diversity and stability to the heat treatment. |
| PubMed:Tocotrienols in Vellozia gigantea leaves: occurrence and modulation by seasonal and plant size effects. |
| PubMed:Serum levels of vitamin E forms and risk of cognitive impairment in a Finnish cohort of older adults. |
| PubMed:Vitamin E analyses in seeds reveal a dominant presence of tocotrienols over tocopherols in the Arecaceae family. |
| PubMed:Identification of α-tocotrienolquinone epoxides and development of an efficient molecular distillation procedure for quantitation of α-tocotrienol oxidation products in food matrices by high-performance liquid chromatography with diode array and fluorescence detection. |
| PubMed:Separation of α-tocotrienol oxidation products and eight tocochromanols by HPLC with DAD and fluorescence detection and identification of unknown peaks by DAD, PBI-EIMS, FTIR, and NMR. |
| PubMed:Intake of antioxidants and risk of type 2 diabetes in a cohort of male smokers. |
| PubMed:Antioxidant activity and inhibition of lipid peroxidation in germinating seeds of transgenic soybean expressing OsHGGT. |
| PubMed:High plasma levels of vitamin E forms and reduced Alzheimer's disease risk in advanced age. |
| PubMed:Tocopherols and tocotrienols in wheat genotypes in the HEALTHGRAIN Diversity Screen. |
| PubMed:Comprehensive analysis of vitamin E constituents in human plasma by liquid chromatography-mass spectrometry. |
| PubMed:A short and convenient chemical route to optically pure 2-methyl chromanmethanols. Total asymmetric synthesis of beta-, gamma-, and delta-tocotrienols. |
| PubMed:Tocopherol and tocotrienol content of hazelnut cultivars grown in portugal. |
| PubMed:Simultaneous determination of vitamin E homologs in chicken meat by liquid chromatography with fluorescence detection. |
| PubMed:Dietary antioxidant intake and risk of type 2 diabetes. |
| PubMed:Normal phase high-performance liquid chromatography method for the determination of tocopherols and tocotrienols in cereals. |
| PubMed:Effects of commercial processing on levels of antioxidants in oats (Avena sativa L.). |
| PubMed:Determination of RS,E/Z-tocotrienols by HPLC. |
| PubMed:Palm tocotrienols protect ApoE +/- mice from diet-induced atheroma formation. |
| PubMed:Biological activity of vitamin E compounds and natural materials by the resorption-gestation test, and chemical determination of the vitamin E activity in foods and feeds. |
| PubMed:The isolation and properties of delta-tocotrienol from Hevea latex. |
|
3D/inchi