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Category:pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless crystalline solid (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 722.82 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 421.00 °F. TCC ( 216.00 °C. ) (est)
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| logP (o/w): | 4.592 (est) |
| Soluble in: |
| | water, 0.007706 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 65 mg/kg
"Kirk-Othmer Encyclopedia of Chemical Technology," 3rd ed., Grayson, M., and D. Eckroth, eds. New York, John Wiley & Sons, Inc., 1978Vol. 3, Pg. 47, 1978.
oral-mouse LD50 350 mg/kg
"Kirk-Othmer Encyclopedia of Chemical Technology," 3rd ed., Grayson, M., and D. Eckroth, eds. New York, John Wiley & Sons, Inc., 1978Vol. 3, Pg. 47, 1978.
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | pharmaceuticals / chemical synthisis |
| Recommendation for lysocellin usage levels up to: | | | not for fragrance use.
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| Recommendation for lysocellin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
View page or View pdf
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| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :3036964 |
| National Institute of Allergy and Infectious Diseases:Data |
| Chemidplus:0055898334 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
Articles:
| Google Patents:Process to produce lysocellin |
| PubMed:Lysocellin, a metabolite of the novel drug 'alopestatin', induces G1 arrest and prevents cytotoxicity induced by etoposide. |
| PubMed:Isolation and characterization of four polyether antibiotics, X-14889A, B, C, and D, closely related to lysocellin and the ferensimycins. |
| PubMed:Three novel polyether antibiotics X-14889A, C, and D from a streptomycete. Taxonomy of the producing organism, fermentation production and biological properties of the antibiotics. |
| PubMed:Circumvention of multidrug resistance in human carcinoma KB cells by polyether antibiotics. |
| PubMed:In vitro effects of the ionophore lysocellin on ruminal fermentation and microbial populations. |
| PubMed:Effect of supplemental lysocellin and tetronasin on growth, ruminal and blood metabolites, and ruminal proteolytic activity in steers grazing ryegrass. |
| PubMed:Effects of lysocellin and calcium level on mineral metabolism, performance and ruminal and plasma characteristics of beef steers. |
| PubMed:The effects of lysocellin and varying calcium levels on performance and ruminal and plasma characteristics of growing beef steers fed corn silage. |
| PubMed:Influence of lysocellin and monensin on mineral metabolism of steers fed forage-based diets. |
| PubMed:Lysocellin effects on growth performance, ruminal fermentation, nutrient digestibility and nitrogen metabolism in steers fed forage diets. |
| PubMed:In vitro study of the effect of different ionophore antibiotics and of certain derivatives on rumen fermentation and on protein nitrogen degradation. |
| PubMed:Effects of lysocellin on performance, ruminal and plasma characteristics of growing cattle. |
| PubMed:Isolation and characterization of three novel polyether antibiotics and three novel actinomycins as cometabolites of the same Streptomyces sp. X-14873, ATCC 31679. |
| PubMed:Ferensimycins A and B. Two polyether antibiotics. Taxonomy, fermentation, isolation, characterization and structural studies. |
| PubMed:Ca2+ ionophores and the activation of human blood platelets. The effects of ionomycin, beauvericin, lysocellin, virginiamycin S, lasalocid-derivatives and McN 4308. |
| PubMed:Studies on the ionophorous antibiotics. XVI. The ionophore-mediated calcium transport and concomitant osmotic swelling of mitochondria. |
| PubMed:The complete assignment of the 13C NMR spectra of lasalocid and the sodium salt-complex of the antibiotic. |
| PubMed:Studies on the ionophorous antibiotics. XI. The artifacts and the degradation products of lysocellin. |
| PubMed:Studies on the ionophorous antibiotics. XII. Effects of ionophore lysocellin on cation distribution and respiration in mitochondria. |
| PubMed:Studies on the ionophorous antibiotics. VIII. Effects of monovalent and divalent cation ionophores on blood platelets. |
| PubMed:Studies on ionophorous antibiotics VII. A broad cation selective ionophore, lysocellin. |
| PubMed:Lysocellin, a new polyether antibiotic. I. Isolation, purification, physico-chemical and biological properties. |
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3D/inchi