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Category:herbicides / pesticides
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 187.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 275.00 °C. @ 760.00 mm Hg
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| Flash Point: | 32.00 °F. TCC ( 0.00 °C. ) (est)
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| logP (o/w): | 1.700 |
| Soluble in: |
| | water, 1600 mg/L @ 25 °C (exp) | | | water, 136 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-dog LD50 > 50 mg/kg
Pesticide Manual. Vol. 9, Pg. 846, 1991.
oral-duck LD50 > 100 mg/kg
Pesticide Manual. Vol. 9, Pg. 846, 1991.
oral-mouse LD50 245 mg/kg
Pesticide Manual. Vol. 9, Pg. 846, 1991.
oral-quail LD50 > 100 mg/kg
Pesticide Manual. Vol. 9, Pg. 846, 1991.
oral-rabbit LDLo 320 mg/kg
Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 14, Pg. 407, 1989.
oral-rat LD50 250 mg/kg
"Agricultural Chemicals," Thomson, W.T., 4 vols., Fresno, CA, Thomson Publications, 1976/77 revisionVol. 4, Pg. 120, 1976/1977.
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| Dermal Toxicity: |
skin-rabbit LD50 > 2000 mg/kg
Pesticide Manual. Vol. 9, Pg. 846, 1991.
skin-rat LD50 > 5000 mg/kg
Nippon Noyaku Gakkaishi. Journal of the Pesticide Science Society of Japan. Vol. 14, Pg. 407, 1989.
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| Inhalation Toxicity: |
inhalation-rat LCLo 3030 mg/m3/1H
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
BEHAVIORAL: ATAXIA
National Technical Information Service. Vol. OTS0543093
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Safety in Use Information:
| Category: | | herbicides / pesticides |
| Recommendation for tricyclazole usage levels up to: | | | not for fragrance use.
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| Recommendation for tricyclazole flavor usage levels up to: |
| | not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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Reasoned opinion on the modification of the existing MRL for tricyclazole in rice
View page or View pdf
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Conclusion on the peer review of the pesticide risk assessment of the active substance tricyclazole
View page or View pdf
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| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA Substance Registry Services (TSCA):41814-78-2 |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :39040 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:1 |
| 8-methyl-[1,2,4]triazolo[3,4-b][1,3]benzothiazole |
| Chemidplus:0041814782 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | blascide | | 8- | methyl-[1,2,4]triazolo[3,4-b][1,3]benzothiazole | | 5- | methyl-1,2,4-triazole(3,4-b)benzothiazole | | 5- | methyl-1,2,4-triazole(3,4-β)benzothiazole | | 5- | methyl-1,2,4-triazolo(3,4-b)(1,3)benzothiazole | | 5- | methyl-1,2,4-triazolo(3,4-b)benzo-1,3-thiazole | | 5- | methyl-1,2,4-triazolo(3,4-b)benzothiazole (9CI) | | 5- | methyl-1,2,4-triazolo[3,4-b]benzo-1,3-thiazole | | 5- | methyl-1,2,4-triazolo[3,4-b]benzothiazole | | 5- | methyl-4-hydro-1,2,4-triazolo[3,4-b]benzothiazole | | 5- | methyl-benzo[4,5]thiazolo[2,3-c][1,2,4]triazole | | 5- | methyl[1,2,4]triazolo[3,4-b][1,3]benzothiazol | | 5- | méthyl[1,2,4]triazolo[3,4-b][1,3]benzothiazole | | | pilarblas | | 1,2,4- | triazolo(3,4-b)benzothiazole, 5-methyl- (9CI) | | 1,2,4- | triazolo[3,4-b]benzothiazole, 5-methyl- | | | tricyclazol | | | trizole |
Articles:
| PubMed:Singlet molecular oxygen generation by light-activated DHN-melanin of the fungal pathogen Mycosphaerella fijiensis in black Sigatoka disease of bananas. |
| PubMed:DOPA and DHN pathway orchestrate melanin synthesis in Aspergillus species. |
| PubMed:Effect of soil organic amendments on the behavior of bentazone and tricyclazole. |
| PubMed:An engineered multidomain fungicidal peptide against plant fungal pathogens. |
| PubMed:Melanin is crucial for growth of the black yeast Hortaea werneckii in its natural hypersaline environment. |
| PubMed:Laboratory and field dissipation of penoxsulam, tricyclazole and profoxydim in rice paddy systems. |
| PubMed:Distribution and persistence of tricyaclazole in agricultural field soils. |
| PubMed:Impact of tricyclazole and azoxystrobin on growth, sporulation and secondary infection of the rice blast fungus, Magnaporthe oryzae. |
| PubMed:Characterization of melanin pigment produced by Aspergillus nidulans. |
| PubMed:Occurrence and distribution study of residues from pesticides applied under controlled conditions in the field during rice processing. |
| PubMed:Determination of tricyclazole content in paddy rice by surface enhanced Raman spectroscopy. |
| PubMed:Physicochemical characterization and antioxidant activity of melanin from a novel strain of Aspergillus bridgeri ICTF-201. |
| PubMed:Trace analysis of pesticides in paddy field water by direct injection using liquid chromatography-quadrupole-linear ion trap-mass spectrometry. |
| PubMed:Pyrazolo[3,4-c]isothiazole and isothiazolo[4,3-d]isoxazole derivatives as antifungal agents. |
| PubMed:Synthesis of new compounds related to the commercial fungicide tricyclazole. |
| PubMed:Fungal pigments inhibit the matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis of darkly pigmented fungi. |
| PubMed:Determination of triazole fungicides in environmental water samples by high performance liquid chromatography with cloud point extraction using polyethylene glycol 600 monooleate. |
| PubMed:Ecotoxicological effects of rice field waters on selected planktonic species: comparison between conventional and organic farming. |
| PubMed:A multi-residue method for pesticide residue analysis in rice grains using matrix solid-phase dispersion extraction and high-performance liquid chromatography-diode array detection. |
| PubMed:Melanin in Fonsecaea pedrosoi: a trap for oxidative radicals. |
| PubMed:Melanin synthesis by Sclerotinia sclerotiorum. |
| PubMed:Growth conditions influence melanization of Brazilian clinical Sporothrix schenckii isolates. |
| PubMed:Daily variation of pesticides in surface water of a small river flowing through paddy field area. |
| PubMed:Physiological effects of tricyclazole on zebrafish (Danio rerio) and post-exposure recovery. |
| PubMed:Conidiation color mutants of Aspergillus fumigatus are highly pathogenic to the heterologous insect host Galleria mellonella. |
| PubMed:Behavior of sprayed tricyclazole in rice paddy lysimeters. |
| PubMed:Multiresidue analysis of 47 pesticides in cooked wheat flour and polished rice by liquid chromatography with tandem mass spectrometry. |
| PubMed:Two homologous fungal carbonyl reductases with different substrate specificities. |
| PubMed:Simulated rainfall removal of tricyclazole sprayed on rice foliage. |
| PubMed:The negative interaction between the degradation of phenanthrene and tricyclazole in medium, soil and soil/compost mixture. |
| PubMed:The influence of ortho- and para-diphenoloxidase substrates on pigment formation in black yeast-like fungi. |
| PubMed:Synthetic pyrazole derivatives as growth inhibitors of some phytopathogenic fungi. |
| PubMed:Univariate near infrared methods for determination of pesticides in agrochemicals. |
| PubMed:Organic amendments affecting sorption, leaching and dissipation of fungicides in soils. |
| PubMed:Effects of tricyclazole (5-methyl-1,2,4-triazol[3,4] benzothiazole), a specific DHN-melanin inhibitor, on the morphology of Fonsecaea pedrosoi conidia and sclerotic cells. |
| PubMed:Studies on the interaction of tricyclazole with beta-cyclodextrin and human serum albumin by spectroscopy. |
| PubMed:Mercury(II) ion-selective polymeric membrane sensors for analysis of mercury in hazardous wastes. |
| PubMed:Emerging antifungal azoles and effects on Magnaporthe grisea. |
| PubMed:Inhibition of melanin synthesis pathway by tricyclazole increases susceptibility of Fonsecaea pedrosoi against mouse macrophages. |
| PubMed:Isolation and antifungal activity of 4-phenyl-3-butenoic acid from Streptomyces koyangensis strain VK-A60. |
| PubMed:Monitoring tricyclazole residues in rice paddy watersheds. |
| PubMed:Appressorium turgor pressure of Colletotrichum kahawae might have a role in coffee cuticle penetration. |
| PubMed:Characterization of the melanin pigment of a cosmopolitan fungal endophyte. |
| PubMed:Changes in dissolved organic carbon of soil amendments with aging: effect on pesticide adsorption behavior. |
| PubMed:Identification of 1,8-dihydroxynaphthalene melanin in Monosporascus cannonballus and the analysis of hexaketide and pentaketide compounds produced by wild-type and pigmented isolates of the fungus. |
| PubMed:The disruption of a Galpha subunit sheds new light on the pathogenicity of Stagonospora nodorum on wheat. |
| PubMed:[Techniques of diseases, insect pests and weeds control and their efficacy in bio-rational rice production]. |
| PubMed:Synthesis and antifungal action of new tricyclazole analogues. |
| PubMed:Evidence for 1,8-dihydroxynaphthalene melanin in three halophilic black yeasts grown under saline and non-saline conditions. |
| PubMed:1,8-dihydroxynaphthalene (DHN)-melanin biosynthesis inhibitors increase erythritol production in Torula corallina, and DHN-melanin inhibits erythrose reductase. |
| PubMed:Melanin biosynthesis in the fungus Curvularia lunata (teleomorph: Cochliobolus lunatus). |
| PubMed:Development of new fungicides against Magnaporthe grisea: synthesis and biological activity of pyrazolo[3,4-d][1,3]thiazine, pyrazolo[1,5-c][1,3,5]thiadiazine, and pyrazolo[3,4-d]pyrimidine derivatives. |
| PubMed:The role of melanin in the antagonistic interaction between the apple scab pathogen Venturia inaequalis and Microsphaeropsis ochracea. |
| PubMed:1,8-Dihydroxynaphthalene monoglucoside, a new metabolite of Sclerotinia sclerotiorum, and the effect of tricyclazole on its production. |
| PubMed:Sphaerolone and dihydrosphaerolone, two bisnaphthyl-pigments from the fungus Sphaeropsidales sp. F-24'707. |
| PubMed:The second naphthol reductase of fungal melanin biosynthesis in Magnaporthe grisea: tetrahydroxynaphthalene reductase. |
| PubMed:Extraction of tricyclazole from soil and sediment with subcritical water. |
| PubMed:Biosynthesis and functions of melanin in Sporothrix schenckii. |
| PubMed:Biosynthesis of cladospirone bisepoxide, a member of the spirobisnaphthalene family. |
| PubMed:Invasive hyphal growth in Wangiella dermatitidis is induced by stab inoculation and shows dependence upon melanin biosynthesis. |
| PubMed:Isolation, antifungal activity, and structure elucidation of the glutarimide antibiotic, streptimidone, produced by Micromonospora coerulea. |
| PubMed:Synthesis and antifungal activities of N-aryl-4-phenyl-3-(4-phenoxyphenyl)butanamides. |
| PubMed:Trihydroxynaphthalene reductase from Magnaporthe grisea: realization of an active center inhibitor and elucidation of the kinetic mechanism. |
| PubMed:Potential interference by free fatty acids in determination of tricyclazole in brown rice by gas chromatography with flame thermionic detection. |
| PubMed:Crystal structure of the ternary complex of 1,3,8-trihydroxynaphthalene reductase from Magnaporthe grisea with NADPH and an active-site inhibitor. |
| PubMed:Crystallization and preliminary x-ray diffraction study of 1 ,3,8-trihydroxynaphthalene reductase from Magnaporthe grisea. |
| PubMed:Melanin production by a filamentous soil fungus in response to copper and localization of copper sulfide by sulfide-silver staining. |
| PubMed:Gas chromatographic determination of systemic fungicide tricyclazole in soil and water. |
| PubMed:Ultrastructure and composition of the conidial wall of Cladosporium cladosporioides. |
| PubMed:Determination of the fungicide trycyclazole in river water, soil and animal samples. |
| PubMed:Melanin biosynthesis and the metabolism of flaviolin and 2-hydroxyjuglone in Wangiella dermatitidis. |
| PubMed:Differentiation and melanin production in hyaline and pigmented strains of Microdochium bolleyi. |
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3D/inchi