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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | yellow-brown powder (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 480.30 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 497.00 °F. TCC ( 258.40 °C. ) (est)
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| logP (o/w): | 0.045 (est) |
| Soluble in: |
| | water, 1e+006 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for 3,4-dihydroxyphenyl lactic acid usage levels up to: | | | not for fragrance use.
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| Recommendation for 3,4-dihydroxyphenyl lactic acid flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | benzeneacetic acid, a,3,4-trihydroxy-a-methyl- | | | dan shen su | | | danshensu | | 2-(3,4- | dihydroxyphenyl)-2-hydroxypropanoic acid | | 3,4- | dihydroxyphenyllactic acid |
Articles:
| PubMed:Protective effects of rosmarinic acid against radiation-induced damage to the hematopoietic system in mice. |
| PubMed:Neuroprotective effect and underlying mechanism of sodium danshensu [3-(3,4-dihydroxyphenyl) lactic acid from Radix and Rhizoma Salviae miltiorrhizae = Danshen] against cerebral ischemia and reperfusion injury in rats. |
| PubMed:Anxiolytic-like effect of danshensu [(3-(3,4-dihydroxyphenyl)-lactic acid)] in mice. |
| PubMed:Redox behaviour of verbascoside and rosmarinic acid. |
| PubMed:Effect of β-(3,4-dihydroxyphenyl)lactic acid on oxidative stress stimulated by high glucose levels in human peritoneal mesothelial cells. |
| PubMed:Protective effects of 3,4-dihydroxyphenyl lactic acid on lipopolysaccharide-induced cerebral microcirculatory disturbance in mice. |
| PubMed:Identification of three novel polyphenolic compounds, origanine A-C, with unique skeleton from Origanum vulgare L. using the hyphenated LC-DAD-SPE-NMR/MS methods. |
| PubMed:In vitro effects of rosmarinic acid on glutathione reductase and glucose 6-phosphate dehydrogenase. |
| PubMed:Contribution of cinnamic acid analogues in rosmarinic acid to inhibition of snake venom induced hemorrhage. |
| PubMed:Effects of dihydroxylphenyl lactic acid on inflammatory responses in spinal cord injury. |
| PubMed:Isolation of a new quinic acid derivative and its antibacterial modulating activity. |
| PubMed:Microwave-assisted extraction with water for fast extraction and simultaneous RP-HPLC determination of phenolic acids in radix Salviae Miltiorrhizae. |
| PubMed:Proteomic screening of antioxidant effects exhibited by radix Salvia miltiorrhiza aqueous extract in cultured rat aortic smooth muscle cells under homocysteine treatment. |
| PubMed:Osteogenic effects of D+beta-3,4-dihydroxyphenyl lactic acid (salvianic acid A, SAA) on osteoblasts and bone marrow stromal cells of intact and prednisone-treated rats. |
| PubMed:[Studies on the chemical constituents of Salvia miltiorrhiz of Lijiang]. |
| PubMed:Ameliorating effects of compounds derived from Salvia miltiorrhiza root extract on microcirculatory disturbance and target organ injury by ischemia and reperfusion. |
| PubMed:Characterization of the radical scavenging and antioxidant activities of danshensu and salvianolic acid B. |
| PubMed:The structure-activity relationship of the series of non-peptide small antagonists for p56lck SH2 domain. |
| PubMed:Separation and determination of three water-soluble compounds in Salvia miltiorrhiza Bunge and two related traditional medicinal preparations by flow injection-capillary electrophoresis. |
| PubMed:A new acylated quercetin glycoside from Ranunculus lanuginosus. |
| PubMed:Simultaneous determination and pharmacokinetic studies on (3,4-Dihydroxyphenyl)-lactic acid and protocatechuic aldehyde in rat serum after oral administration of Radix Salviae miltiorrhizae extract. |
| PubMed:Effect of Salvia miltiorrhiza on aflatoxin B1-induced oxidative stress in cultured rat hepatocytes. |
| PubMed:The mechanism of tyrosinase-catalysed oxidative decarboxylation of alpha-(3,4-dihydroxyphenyl)-lactic acid. |
| PubMed:Salvianolic Acid A, a New Depside from Roots of Salvia miltiorrhiza. |
| PubMed:[Pharmacology of several aromatic amino acid decarboxylase inhibitors]. |
| PubMed:Rosmarinic acid production in Coleus cell cultures. |
| PubMed:Biogenesis of rosmarinic acid in Mentha. |
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3D/inchi