tocopheryl phosphate, 425429-22-7

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PubMed:Final report on the safety assessment of Tocopherol, Tocopheryl Acetate, Tocopheryl Linoleate, Tocopheryl Linoleate/Oleate, Tocopheryl Nicotinate, Tocopheryl Succinate, Dioleyl Tocopheryl Methylsilanol, Potassium Ascorbyl Tocopheryl Phosphate, and Tocophersolan.

PubMed:Topical application of a novel oxycodone gel formulation (tocopheryl phosphate mixture) in a rat model of peripheral inflammatory pain produces localized pain relief without significant systemic exposure.

PubMed:The α-tocopherol derivative ESeroS-GS induces cell death and inhibits cell motility of breast cancer cells through the regulation of energy metabolism.

PubMed:Induction of VEGF expression by alpha-tocopherol and alpha-tocopheryl phosphate via PI3Kγ/PKB and hTAP1/SEC14L2-mediated lipid exchange.

PubMed:α-Tocopheryl Phosphate as a Bioactive Derivative of Vitamin E: A Review of the Literature.

PubMed:Modulation of phosphorylation of tocopherol and phosphatidylinositol by hTAP1/SEC14L2-mediated lipid exchange.

PubMed:α-Tocopheryl-phosphate regulation of gene expression in preadipocytes and adipocytes.

PubMed:The vitamin E derivative, EPC-K1, suppresses inflammation during hepatic ischemia-reperfusion injury and exerts hepatoprotective effects in rats.

PubMed:α-Tocopheryl phosphate--an activated form of vitamin E important for angiogenesis and vasculogenesis?

PubMed:α-tocopherol and α-tocopheryl phosphate interact with the cannabinoid system in the rodent hippocampus.

PubMed:The antioxidant EPC-K1 attenuates renal ischemia-reperfusion injury in a rat model.

PubMed:α-Tocopheryl phosphate: uptake, hydrolysis, and antioxidant action in cultured cells and mouse.

PubMed:Modulation of gene expression by α-tocopherol and α-tocopheryl phosphate in THP-1 monocytes.

PubMed:Importance of EPC-K1 in ischemia and reperfusion injury.

PubMed:alpha-Tocopherol enhances degranulation in RBL-2H3 mast cells.

PubMed:alpha-Tocopheryl phosphate--an active lipid mediator?

PubMed:Vitamin E and cancer.

PubMed:alpha-Tocopherol administration produces an antidepressant-like effect in predictive animal models of depression.

PubMed:Effect of tocopheryl phosphate on key biomarkers of inflammation: Implication in the reduction of atherosclerosis progression in a hypercholesterolaemic rabbit model.

PubMed:alpha-tocopheryl phosphate suppresses tumor invasion concurrently with dynamic morphological changes and delocalization of cortactin from invadopodia.

PubMed:Inhibitory effect of antioxidants on hydroxyl radical generation from methylguanidine: an ESR study.

PubMed:Cardioprotection with alpha-tocopheryl phosphate: amelioration of myocardial ischemia reperfusion injury is linked with its ability to generate a survival signal through Akt activation.

PubMed:Modulation of proteasome activity by vitamin E in THP-1 monocytes.

PubMed:Comparison of nitric oxide synthase inhibitors, phospholipase A2 inhibitor and free radical scavengers as attenuators of opioid withdrawal syndrome.

PubMed:Differential effects of the ascorbyl and tocopheryl derivative on the methamphetamine-induced toxic behavior and toxicity.

PubMed:Cellular, molecular and clinical aspects of vitamin E on atherosclerosis prevention.

PubMed:Molecular mechanism of alpha-tocopheryl-phosphate transport across the cell membrane.

PubMed:Molecular and cellular activities of vitamin E analogues.

PubMed:Alpha-tocopheryl phosphate is a novel apoptotic agent.

PubMed:The effect of tocopheryl phosphates on atherosclerosis progression in rabbits fed with a high cholesterol diet.

PubMed:Evaluation of the safety of mixed tocopheryl phosphates (MTP) -- a formulation of alpha-tocopheryl phosphate plus alpha-di-tocopheryl phosphate.

PubMed:Alpha-tocopheryl phosphate: a novel, natural form of vitamin E.

PubMed:On the existence of cellular tocopheryl phosphate, its synthesis, degradation and cellular roles: a hypothesis.

PubMed:Modulation of cell proliferation and gene expression by alpha-tocopheryl phosphates: relevance to atherosclerosis and inflammation.

PubMed:The therapeutic role of taurine in ischaemia-reperfusion injury.

PubMed:Dentin is dissolved by high concentrations of L-ascorbic acid 2-[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl-hydrogen phosphate] potassium salt with or without hydrogen peroxide.

PubMed:Modulation of cell proliferation and gene expression by alpha-tocopheryl phosphates: relevance to atherosclerosis and inflammation.

PubMed:A novel antioxidant, EPC-K1, stimulates endothelial nitric oxide production and scavenges hydroxyl radicals.

PubMed:The antioxidant EPC-K1 ameliorates brain injury by inhibiting lipid peroxidation in a rat model of transient focal cerebral ischaemia.

PubMed:EPC-K1 reduces the expression of inducible nitric oxide synthase (iNOS) in delayed neuronal death (DND).

PubMed:Effects of a hydroxyl radical scavenger, EPC-K1, and neutrophil depletion on reperfusion injury in rat skeletal muscle.

PubMed:Attenuation of oxidative DNA damage with a novel antioxidant EPC-K1 in rat brain neuronal cells after transient middle cerebral artery occlusion.

PubMed:Combination of a free radical scavenger and heparin reduces cerebral hemorrhage after heparin treatment in a rabbit middle cerebral artery occlusion model.

PubMed:Nitric oxide induces oxidative stress and apoptosis in neuronal cells.

PubMed:Novel approach to in vivo screening for radioprotective activity in whole mice: in vivo electron spin resonance study probing the redox reaction of nitroxyl.

PubMed:Characterization of the activity of L-ascorbic acid 2-[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-be nzopyran-6-yl-hydrogen phosphate] potassium salt in hydroxyl radical elimination.

PubMed:Effects of EPC-K1 on lipid peroxidation in experimental spinal cord injury.

PubMed:EPC-K1, a hydroxyl radical scavenger, prevents 6-hydroxydopamine-induced dopamine depletion in the mouse striatum by up-regulation of catalase activity.

PubMed:Kupffer cell-independent acute hepatocellular oxidative stress and decreased bile formation in post-cold-ischemic rat liver.

PubMed:The antioxidant EPC-K1 attenuates NO-induced mitochondrial dysfunction, lipid peroxidation and apoptosis in cerebellar granule cells.

PubMed:Reduced reperfusion injury in muscle. A comparison of the timing of EPC-K1 administration in rats.

PubMed:Antioxidant properties of EPC-K1: a study on mechanisms.

PubMed:EPC-K1 attenuates peroxynitrite-induced apoptosis in cerebellar granule cells.

PubMed:Hydroxyl radical generation after the third hour following ischemia contributes to brain damage.

PubMed:Restoration of the glucocorticoid receptor function by the phosphodiester compound of vitamins C and E, EPC-K1 (L-ascorbic acid 2-[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1-benzopyran-6-yl hydrogen phosphate] potassium salt), via a redox-dependent mechanism.

PubMed:Inhibition of NF-kappaB-dependent transcription of human immunodeficiency virus 1 promoter by a phosphodiester compound of vitamin C and vitamin E, EPC-K1.

PubMed:Effect of EPC-K1 on myocardial infarct size in a rat model with coronary artery occlusion and reperfusion.

PubMed:Global ischemic neuronal damage relates to behavioural deficits: a pharmacological approach.

PubMed:Reduced ischemia-reperfusion injury in muscle. Experiments in rats with EPC-K1, a new radical scavenger.

PubMed:The effect of combination therapy with EPC-K1 and low-dose cyclosporine to pulmonary allograft after rat lung transplantation.

PubMed:[Effect of phosphate diester linkage of vitamin E and vitamin C (EPC-K1) on myocardial ischemia reperfusion injury in the isolated working rat heart].

PubMed:EPC-K1 is effective in lung preservation in an ex vivo rabbit lung perfusion model.

PubMed:Hepatropic soluble vitamin E derivative EPC-K1 prevents warm ischemia/reperfusion injury of non-heart-beating donor liver transplantation in pigs.

PubMed:Enhancing effect of thoraco-laparotomy on liver metastasis and the role played by active oxygens in its mechanism.

PubMed:Inhibitory effects of a phosphate diester of alpha-tocopherol and ascorbic acid (EPC-K1) on myocardial infarction in rats.

PubMed:Posttreatment with EPC-K1, an inhibitor of lipid peroxidation and of phospholipase A2 activity, reduces functional deficits after global ischemia in rats.

PubMed:Effects of L-ascorbic acid 2-[3,4-dihydro-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-2H-1- benzopyran-6yl-hydrogen phosphate] potassium salt on cerebral energy state and consciousness recovery following transient forebrain ischemia in gerbils.

PubMed:[Stability studies on L-ascorbic acid dl-alpha-tocopherol phosphoric acid diester potassium salt (EPC-K)].

PubMed:Cytoprotective effect of tocopherols in hepatocytes cultured with polyunsaturated fatty acids.

PubMed:Beneficial effect of EPC-K1 on the survival of warm ischemic damaged graft in rat cardiac transplantation.

PubMed:[Effectiveness of various pharmaceutical forms of alfa-tocopherol].

PubMed:[Comparison of the effectiveness of oil and water solutions of alpha-tocopherol as radiation protection agent].

PubMed:Determination of pipamperone in human plasma by high performance liquid chromatography.

PubMed:A newly developed hydroxyl radical scavenger, EPC-K1 can improve the survival of swine warm ischemia-damaged transplanted liver grafts.

PubMed:[Phosphocreatine, tocopheryl phosphate and their combination in acute ischemia and myocardial reperfusion in dogs: the effect on rhythm disorders, left ventricle contractility and infarct size].

PubMed:Effect of ferric ion and active oxygen scavenger on monoamine release in the striatum of the rat.

PubMed:[The effect of alpha-tocopherol in water-soluble form on human erythrocyte membranes while in contact with oxygen].

PubMed:[Improving the contractility and metabolism of the isolated rat heart during post-ischemia reperfusion with phosphocreatine, tocopheryl phosphate and their combination].

PubMed:[Mechanisms of the conduction of cellular regulatory signals].

PubMed:Increased activity of cyclic AMP phosphodiesterase from frozen-thawed rat liver. A role of lysosomal protease in enzyme activation.

PubMed:[Effect of alpha-tocopheryl phosphate (alpha-TPh) on D-amino acid oxidase and aminoxidase of rat liver homogenates].

PubMed:[The effect of alpha-tocopheryl phosphate (alpha-TPh) on aminoxidase of normal rat diaphragm].

PubMed:On the mechanism of action of alpha-tocopheryl phosphate, with special reference to carbohydrate metabolism of striated muscle. III. Inhibition of insulin-induced glycogenesis in isolated rat diaphragm.

PubMed:On the mechanism of action of alpha-tocopheryl phosphate, with special reference to carbohydrate metabolism of striated muscle. II. Effect on the capacity of rat diaphragm to dissimilate hexose phosphates.

PubMed:On the mechanism of action of alpha-tocopheryl phosphate, with special reference to carbohydrate metabolism of striated muscle. I. Modification of epinephrine effect, hyperlactacidemia, by alpha-tocopheryl phosphate in the rat.

PubMed:[Results with tocopheryl phosphate and inositol therapy of Erb's progressive muscular dystrophy].

PubMed:Effect of alpha-tocopheryl phosphate on enzyme activity.

PubMed:The locus of action of alpha-tocopheryl phosphate in the succinoxidase system.

PubMed:The effect of alpha-tocopheryl phosphate on the inhibition of phosphatase by estrogens in vitro.

PubMed:On the antithrombic and antiproteolytic activity of alpha tocopheryl phosphate.

PubMed:The Effect of agr-Tocopheryl Phosphate on Diphosphopyridine Nucleotidase.

PubMed:Effect of calcium on the inhibition of the succinic oxidase system by d-alpha-tocopheryl phosphate.

PubMed:Effect of calcium on the inhibition of the succinic oxidase system by delta-tocopheryl phosphate.

tocopheryl phosphate

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