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quinic acid
cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1alpha,3alpha,4alpha,5beta)-

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Name:(3S,5S)-1,3,4,5-tetrahydroxycyclohexane-1-carboxylic acid
CAS Number: 36413-60-2Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:253-023-5
XlogP3-AA:-2.40 (est)
Molecular Weight:192.16784000
Formula:C7 H12 O6
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:buffering agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 438.42 °C. @ 760.00 mm Hg (est)
Flash Point: 452.00 °F. TCC ( 233.10 °C. ) (est)
logP (o/w): -2.023 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: buffering agents
Chemical Sources Association
Need This Item for Flavor/Food?: You can contact the Chemical Sources Association
Safety Information:
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
buffering agents
Recommendation for quinic acid usage levels up to:
 not for fragrance use.
Recommendation for quinic acid flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :37439
National Institute of Allergy and Infectious Diseases:Data
(3S,5S)-1,3,4,5-tetrahydroxycyclohexane-1-carboxylic acid
 (3S,5S)-1,3,4,5-tetrahydroxycyclohexane-1-carboxylic acid
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):37439
Pubchem (sid):134998903
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):HMDB03072
VCF-Online:VCF Volatile Compounds in Food
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
Search PMC Picture
 cyclohexanecarboxylic acid, 1,3,4,5-tetrahydroxy-, (1alpha,3alpha,4alpha,5beta)-
L-quinic acid
laevo-quinic acid
(1alpha,3alpha,4alpha,5beta)-1,3,4,5-tetrahydroxycyclohexane carboxylic acid
(3S,5S)-1,3,4,5-tetrahydroxycyclohexane-1-carboxylic acid
(3s,5s)-1,3,4,5-tetrahydroxycyclohexanecarboxylic acid
1,3,4,5-tetrahydroxycyclohexanecarboxylic acid (1alpha,3alpha,4alpha,5beta)-


PubMed:Herbal products containing Hibiscus sabdariffa L., Crataegus spp., and Panax spp.: Labeling and safety concerns.
PubMed:Phenolic compounds from three brown seaweed species using LC-DAD-ESI-MS/MS.
PubMed:Potential effect of compounds isolated from Coffea arabica against UV-B induced skin damage by protecting fibroblast cells.
PubMed:LC-ESI-TOF-MS and GC-MS profiling of Artemisia herba-alba and evaluation of its bioactive properties.
PubMed:Extraction, identification and assessment of antioxidative compounds of bran extracts of traditional rice cultivars: An analytical approach.
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PubMed:UHPLC-Q-Orbitrap-HRMS-based global metabolomics reveal metabolome modifications in plasma of young women after cranberry juice consumption.
PubMed:An Unambiguous Nomenclature for the Acyl-quinic Acids Commonly Known as Chlorogenic Acids.
PubMed:Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome.
PubMed:Bioactive Components and Antioxidant Capacity of Fruits from Nine Sorbus Genotypes.
PubMed:An Efficient Method for the Preparative Isolation and Purification of Flavonoid Glycosides and Caffeoylquinic Acid Derivatives from Leaves of Lonicera japonica Thunb. Using High Speed Counter-Current Chromatography (HSCCC) and Prep-HPLC Guided by DPPH-HPLC Experiments.
PubMed:Chemical Composition and Antioxidant Activity of Euterpe oleracea Roots and Leaflets.
PubMed:Hydrolysis of Dicaffeoylquinic Acids from Ilex kudingcha Happens in the Colon by Intestinal Microbiota.
PubMed:NMR metabolomics demonstrates phenotypic plasticity of sea buckthorn (Hippophaë rhamnoides) berries with respect to growth conditions in Finland and Canada.
PubMed:Selective enzymatic hydrolysis of chlorogenic acid lactones in a model system and in a coffee extract. Application to reduction of coffee bitterness.
PubMed:Inhibitory effect of chlorogenic acid on digestion of potato starch.
PubMed:Four New Dicaffeoylquinic Acid Derivatives from Glasswort (Salicornia herbacea L.) and Their Antioxidative Activity.
PubMed:HPLC-DAD-ESI-MS(2) analytical profile of extracts obtained from purple sweet potato after green ultrasound-assisted extraction.
PubMed:Immobilized tannase treatment alters polyphenolic composition in teas and their potential anti-obesity and hypoglycemic activities in vitro.
PubMed:Rapid Identification and Comparison of Compounds with Antioxidant Activity in Coreopsis tinctoria Herbal Tea by High-Performance Thin-Layer Chromatography Coupled with DPPH Bioautography and Densitometry.
PubMed:Synthesis, Structure, and Tandem Mass Spectrometric Characterization of the Diastereomers of Quinic Acid.
PubMed:Salinity effect on nutritional value, chemical composition and bioactive compounds content of Cichorium spinosum L.
PubMed:Analysis of a series of chlorogenic acid isomers using differential ion mobility and tandem mass spectrometry.
PubMed:Profiling Taste and Aroma Compound Metabolism during Apricot Fruit Development and Ripening.
PubMed:Facile Separation of 5-O-Galloylquinic Acid from Chinese Green Tea Extract using Mesoporous Zirconium Phosphate.
PubMed:Identification of Phenolic Compounds in Red and Green Pistachio (Pistacia vera L.) Hulls (Exo- and Mesocarp) by HPLC-DAD-ESI-(HR)-MS(n).
PubMed:Phenolic Profile and Antioxidant Potential of Leaves from Selected Cotoneaster Medik. Species.
PubMed:Characterisation of phenolic antioxidants in Scabiosa arenaria flowers by LC-ESI-MS/MS and NMR.
PubMed:Comparative study of the antioxidative activities of caffeoylquinic and caffeic acids.
PubMed:In vitro assessment of potential intestinal absorption of some phenolic families and carboxylic acids from commercial instant coffee samples.
PubMed:A novel procedure for the assessment of the antioxidant capacity of food components.
PubMed:Phytochemical Analysis and Antifungal Activity of Extracts from Leaves and Fruit Residues of Brazilian Savanna Plants Aiming Its Use as Safe Fungicides.
PubMed:Anti-inflammatory and anti-oxidant effect of Calea urticifolia lyophilized aqueous extract on lipopolysaccharide-stimulated RAW 264.7 macrophages.
PubMed:Antioxidants and α-glucosidase inhibitors from Ipomoea batatas leaves identified by bioassay-guided approach and structure-activity relationships.
PubMed:Microbial biotransformation of polyphenols during in vitro colonic fermentation of masticated mango and banana.
PubMed:Phenolic acid degradation potential and growth behavior of lactic acid bacteria in sunflower substrates.
PubMed:Hydrophilic antioxidants from Andean tomato landraces assessed by their bioactivities in vitro and in vivo.
PubMed:Development of Marker-Free Transgenic Potato Tubers Enriched in Caffeoylquinic Acids and Flavonols.
PubMed:Phenolic Profile and Biological Activities of the Pepino (Solanum muricatum) Fruit and Its Wild Relative S. caripense.
PubMed:Distribution of Major Chlorogenic Acids and Related Compounds in Brazilian Green and Toasted Ilex paraguariensis (Maté) Leaves.
PubMed:Metabolic Response of Strawberry (Fragaria x ananassa) Leaves Exposed to the Angular Leaf Spot Bacterium (Xanthomonas fragariae).
PubMed:Chlorogenic acid ameliorates intestinal mitochondrial injury by increasing antioxidant effects and activity of respiratory complexes.
PubMed:Fresh from the Ornamental Garden: Hips of Selected Rose Cultivars Rich in Phytonutrients.
PubMed:Dicaffeoylquinic Acid-Enriched Fraction of Cichorium glandulosum Seeds Attenuates Experimental Type 1 Diabetes via Multipathway Protection.
PubMed:Antiamnesic Effect of Actinidia arguta Extract Intake in a Mouse Model of TMT-Induced Learning and Memory Dysfunction.
PubMed:Matching in Vitro Bioaccessibility of Polyphenols and Antioxidant Capacity of Soluble Coffee by Boosted Regression Trees.
PubMed:Fruit Phenolic Composition of Different Elderberry Species and Hybrids.
PubMed:Flavonoids and Methoxy-galloylquinic Acid Derivatives from the Leaf Extract of Copaifera langsdorffii Desf.
PubMed:Caffeoylquinic acids competitively inhibit pancreatic lipase through binding to the catalytic triad.
PubMed:Effect of 5-caffeoylquinic acid on the NF-κB signaling pathway, peroxisome proliferator-activated receptor gamma 2, and macrophage infiltration in high-fat diet-fed Sprague-Dawley rat adipose tissue.
PubMed:Neochlorogenic Acid Inhibits Lipopolysaccharide-Induced Activation and Pro-inflammatory Responses in BV2 Microglial Cells.
PubMed:Melissa officinalis L. decoctions as functional beverages: a bioactive approach and chemical characterization.
PubMed:Metal Complex Pigment Involved in the Blue Sepal Color Development of Hydrangea.
PubMed:Determination of caffeoylquinic acids in feed and related products by focused ultrasound solid-liquid extraction and ultra-high performance liquid chromatography-mass spectrometry.
PubMed:The effects of juice processing on black mulberry antioxidants.
PubMed:Effect of repeated harvesting on the content of caffeic acid and seven species of caffeoylquinic acids in sweet potato leaves.
PubMed:Chlorogenic acid-arabinose hybrid domains in coffee melanoidins: Evidences from a model system.
PubMed:Chlorogenic acid stability in pressurized liquid extraction conditions.
PubMed:Rapid Fingerprint Analysis of Plant Extracts for Ellagitannins, Gallic Acid, and Quinic Acid Derivatives and Quercetin-, Kaempferol- and Myricetin-Based Flavonol Glycosides by UPLC-QqQ-MS/MS.
PubMed:Comprehensive 3-year study of the phenolic profile of Moroccan monovarietal virgin olive oils from the Meknès region.
PubMed:Flavor of fresh blueberry juice and the comparison to amount of sugars, acids, anthocyanidins, and physicochemical measurements.
PubMed:Parallel reductions in phenolic constituents resulting from the domestication of eggplant.
PubMed:Inhibitory activities of caffeoylquinic acid derivatives from Ilex kudingcha C.J. Tseng on α-glucosidase from Saccharomyces cerevisiae.
PubMed:Effects of caffeic and 5-caffeoylquinic acids on cell viability and cellular uptake in human colon adenocarcinoma cells.
PubMed:Characterization and quantitative analysis of phenylpropanoid amides in eggplant (Solanum melongena L.) by high performance liquid chromatography coupled with diode array detection and hybrid ion trap time-of-flight mass spectrometry.
PubMed:Polyphenols from artichoke heads (Cynara cardunculus (L.) subsp. scolymus Hayek): in vitro bio-accessibility, intestinal uptake and bioavailability.
PubMed:(1S,3R,4S,5R)5-O-Caffeoylquinic acid: isolation, stereo-structure characterization and biological activity.
PubMed:Solvent system selectivities in countercurrent chromatography using Salicornia gaudichaudiana metabolites as practical example with off-line electrospray mass-spectrometry injection profiling.
PubMed:Role of degradation products of chlorogenic acid in the antioxidant activity of roasted coffee.
PubMed:Anthocyanins and antioxidant capacities of six Chilean berries by HPLC-HR-ESI-ToF-MS.
PubMed:Antioxidant components of Viburnum opulus L. determined by on-line HPLC-UV-ABTS radical scavenging and LC-UV-ESI-MS methods.
PubMed:Metabolism of phenolic compounds by Lactobacillus spp. during fermentation of cherry juice and broccoli puree.
PubMed:Changes in sugars and organic acids in wolfberry (Lycium barbarum L.) fruit during development and maturation.
PubMed:Carboxymethyl- and carboxyl-catechins from ripe Pu-er tea.
PubMed:In vitro enzymic hydrolysis of chlorogenic acids in coffee.
PubMed:Influence of sulfur fumigation on the chemical constituents and antioxidant activity of buds of Lonicera japonica.
PubMed:Transformation of 5-O-caffeoylquinic acid in blueberries during high-temperature processing.
PubMed:Dual catalytic activity of hydroxycinnamoyl-coenzyme A quinate transferase from tomato allows it to moonlight in the synthesis of both mono- and dicaffeoylquinic acids.
PubMed:Identification and characterization of chlorogenic acids, chlorogenic acid glycosides and flavonoids from Lonicera henryi L. (Caprifoliaceae) leaves by LC-MSn.
PubMed:5-Caffeoylquinic acid decreases diet-induced obesity in rats by modulating PPARα and LXRα transcription.
PubMed:Interaction of chlorogenic acids and quinides from coffee with human serum albumin.
PubMed:Effects of domestic cooking methods on polyphenols and antioxidant activity of sweet potato leaves.
PubMed:Thermal transformation of trans-5-O-caffeoylquinic acid (trans-5-CQA) in alcoholic solutions.
PubMed:Investigation of acyl migration in mono- and dicaffeoylquinic acids under aqueous basic, aqueous acidic, and dry roasting conditions.
PubMed:Single-laboratory validation for the determination of caffeic acid and seven caffeoylquinic acids in sweet potato leaves.
PubMed:Precursor ion scan driven fast untargeted screening and semi-determination of caffeoylquinic acid derivatives in Cynara scolymus L.
PubMed:A rapid method for quantifying chlorogenic acid levels in potato samples.
PubMed:Inhibition by caffeic acid of the influenza A virus multiplication in vitro.
PubMed:Variations in caffeine and chlorogenic acid contents of coffees: what are we drinking?
PubMed:Synergistic effect of quercetin and quinic acid by alleviating structural degeneration in the liver, kidney and pancreas tissues of STZ-induced diabetic rats: a mechanistic study.
PubMed:Water scarcity conditions affect peach fruit size and polyphenol contents more severely than other fruit quality traits.
PubMed:Impact of dose on the bioavailability of coffee chlorogenic acids in humans.
PubMed:Chemical analysis and antihyperglycemic activity of an original extract from burdock root (Arctium lappa).
PubMed:Sweet potato (Ipomoea batatas [L.] Lam)--a valuable medicinal food: a review.
PubMed:Metabolic engineering of Escherichia coli for improving shikimate synthesis from glucose.
PubMed:Identification and quantitative determination of the polar constituents in Helichrysum italicum flowers and derived food supplements.
PubMed:Consumption of a dark roast coffee decreases the level of spontaneous DNA strand breaks: a randomized controlled trial.
PubMed:Identification of α-glucosidase inhibitors from the leaves of Pluchea indica (L.) Less., a traditional Indonesian herb: promotion of natural product use.
PubMed:Evolution of polyphenols and organic acids during the fermentation of apple cider.
PubMed:In vitro transformation of chlorogenic acid by human gut microbiota.
PubMed:Effects of boiling on chlorogenic acid and the liver protective effects of its main products against CCl₄-induced toxicity in vitro.
PubMed:Preparative isolation of aldose reductase inhibitory compounds from Nardostachys chinensis by elution-extrusion counter-current chromatography.
PubMed:Persea americana Mill. Seed: Fractionation, Characterization, and Effects on Human Keratinocytes and Fibroblasts.
PubMed:On-line process monitoring of coffee roasting by resonant laser ionisation time-of-flight mass spectrometry: bridging the gap from industrial batch roasting to flavour formation inside an individual coffee bean.
PubMed:Inhibition of the β-catenin/Tcf signaling by caffeoylquinic acids in sweet potato leaf through down regulation of the Tcf-4 transcription.
PubMed:Efficient ethanol production from brown macroalgae sugars by a synthetic yeast platform.
PubMed:Quantitative studies on roast kinetics for bioactives in coffee.
PubMed:Impact of chemical changes on the sensory characteristics of coffee beans during storage.
PubMed:Gymnaster koraiensis and its major components, 3,5-di-O-caffeoylquinic acid and gymnasterkoreayne B, reduce oxidative damage induced by tert-butyl hydroperoxide or acetaminophen in HepG2 cells.
PubMed:Metabolic differentiation of diamondback moth ( Plutella xylostella (L.)) resistance in cabbage ( Brassica oleracea L. ssp. capitata).
PubMed:Phenolic profile and antioxidant activity of Serbian polyfloral honeys.
PubMed:Dried plums and their products: composition and health effects--an updated review.
PubMed:Antioxidant and genoprotective effects of spent coffee extracts in human cells.
PubMed:Resistance to the weevils Cylas puncticollis and Cylas brunneus conferred by sweetpotato root surface compounds.
PubMed:Citron and lemon under the lens of HR-MAS NMR spectroscopy.
PubMed:Identification and quantification of free, conjugate and total phenolic compounds in leaves of 20 sweetpotato cultivars by HPLC-DAD and HPLC-ESI-MS/MS.
PubMed:A new method for the preparative isolation of chlorogenic acid lactones from coffee and model roasts of 5-caffeoylquinic acid.
PubMed:Milk whey protein modification by coffee-specific phenolics: effect on structural and functional properties.
PubMed:An outlook on chlorogenic acids-occurrence, chemistry, technology, and biological activities.
PubMed:Anti-Aspergillus activity of green coffee 5-O-caffeoyl quinic acid and its alkyl esters.
PubMed:Caffeoylquinic acid-rich purple sweet potato extract, with or without anthocyanin, imparts neuroprotection and contributes to the improvement of spatial learning and memory of SAMP8 mouse.
PubMed:Aldose reductase inhibitory compounds from Xanthium strumarium.
PubMed:Diversity of (dihydro) hydroxycinnamic acid conjugates in Colombian potato tubers.
PubMed:The impact of Ca2+ combination with organic acids on green tea infusions.
PubMed:Structure- and dose-absorption relationships of coffee polyphenols.
PubMed:Characterization of genes for a putative hydroxycinnamoyl-coenzyme A quinate transferase and p-coumarate 3'-hydroxylase and chlorogenic acid accumulation in tartary buckwheat.
PubMed:HPLC-DAD-ESI/MS identification and quantification of phenolic compounds in Ilex paraguariensis beverages and on-line evaluation of individual antioxidant activity.
PubMed:Absorption and isomerization of caffeoylquinic acids from different foods using ileostomist volunteers.
PubMed:Bioavailability of dietary (poly)phenols: a study with ileostomists to discriminate between absorption in small and large intestine.
PubMed:Metabolic profiling of Chinese tobacco leaf of different geographical origins by GC-MS.
PubMed:Carotenoids and phenolic compounds from Solanum sessiliflorum, an unexploited Amazonian fruit, and their scavenging capacities against reactive oxygen and nitrogen species.
PubMed:Determination of α-hydroxy acids and their enantiomers in fruit juices by ligand exchange CE with a dual central metal ion system.
PubMed:Radical scavenging activity and cytotoxicity of active quinic acid derivatives from Scorzonera divaricata roots.
PubMed:Identification of organic acids in Cichorium intybus inhibiting virulence-related properties of oral pathogenic bacteria.
PubMed:Adhesive microbeads for the targeting delivery of anticaries agents of vegetable origin.
PubMed:Polyphenolics composition of the leaves of Zanthoxylum bungeanum Maxim. grown in Hebei, China, and their radical scavenging activities.
PubMed:Quantitative fate of chlorogenic acid during enzymatic browning of potato juice.
PubMed:Dietary intake and major food sources of polyphenols in a Spanish population at high cardiovascular risk: the PREDIMED study.
PubMed:Degradation kinetics of chlorogenic acid at various pH values and effects of ascorbic acid and epigallocatechin gallate on its stability under alkaline conditions.
PubMed:Biotransformation of 4,5-O-dicaffeoylquinic acid methyl ester by human intestinal flora and evaluation on their inhibition of NO production and antioxidant activity of the products.
PubMed:Characterization of Changes in Polyphenols, Antioxidant Capacity and Physico-Chemical Parameters during Lowbush Blueberry Fruit Ripening.
PubMed:Radioprotection by two phenolic compounds: chlorogenic and quinic acid, on X-ray induced DNA damage in human blood lymphocytes in vitro.
PubMed:Screening and identification of the antibacterial bioactive compounds from Lonicera japonica Thunb. leaves.
PubMed:Ni speciation in tea infusions by monolithic chromatography--ICP-MS and Q-TOF-MS.
PubMed:Evaluation of spent coffee obtained from the most common coffeemakers as a source of hydrophilic bioactive compounds.
PubMed:Comparative evaluation of cultivars of Chrysanthemum morifolium flowers by HPLC-DAD-ESI/MS analysis and antiallergic assay.
PubMed:Formation of ester and amine derivatives of 5-O-caffeoylquinic acid in the process of its simulated extraction.
PubMed:Identification of phenolic constituents in Cichorium endivia var. crispum and var. latifolium salads by high-performance liquid chromatography with diode array detection and electrospray ioniziation tandem mass spectrometry.
PubMed:Inhibitory activity of Aralia continentalis roots on protein tyrosine phosphatase 1B and rat lens aldose reductase.
PubMed:Antioxidant and DNA-protective activities of chlorogenic acid isomers.
PubMed:Peach fruit: metabolic comparative analysis of two varieties with different resistances to insect attacks by NMR spectroscopy.
PubMed:Identification and quantification of constituents of Gardenia jasminoides Ellis (Zhizi) by HPLC-DAD-ESI-MS.
PubMed:Polyphenols extracted from black tea (Camellia sinensis) residue by hot-compressed water and their inhibitory effect on pancreatic lipase in vitro.
PubMed:Investigating the chemical changes of chlorogenic acids during coffee brewing: conjugate addition of water to the olefinic moiety of chlorogenic acids and their quinides.
PubMed:Effects of temperature and photoperiod on yield and chemical composition of northern and southern clones of bilberry (Vaccinium myrtillus L.).
PubMed:(13)C NMR-based metabolomics for the classification of green coffee beans according to variety and origin.
PubMed:Effect of coffee combining green coffee bean constituents with typical roasting products on the Nrf2/ARE pathway in vitro and in vivo.
PubMed:Characterization of the polymerization of furfuryl alcohol during roasting of coffee.
PubMed:Anti-inflammatory and anti-angiogenic effects of flavonoids isolated from Lycium barbarum Linnaeus on human umbilical vein endothelial cells.
PubMed:Effect of maturation and cold storage on the organic acid composition of myrtle fruits.
PubMed:Content of antioxidative caffeoylquinic acid derivatives in field-grown Ligularia fischeri (Ledeb.) Turcz and responses to sunlight.
PubMed:The anticarcinogenic potential of essential oil and aqueous infusion from caper (Capparis spinosa L.).
PubMed:Comparative analysis of caffeoylquinic acids and lignans in roots and seeds among various burdock (Arctium lappa) genotypes with high antioxidant activity.
PubMed:Chemical descriptors for sensory and parental origin of commercial Coffea genotypes.
PubMed:Ultraviolet-B light treatment increases antioxidant capacity of carrot products.
PubMed:Effects of genotype, latitude, and weather conditions on the composition of sugars, sugar alcohols, fruit acids, and ascorbic acid in sea buckthorn (Hippophaë rhamnoides ssp. mongolica) berry juice.
PubMed:Polyphenol compounds in artichoke plant tissues and varieties.
PubMed:Roasting process of coffee beans as studied by nuclear magnetic resonance: time course of changes in composition.
PubMed:Identification of nutritional descriptors of roasting intensity in beverages of Arabica and Robusta coffee beans.
PubMed:Food components with anticaries activity.
PubMed:Caffeoylquinic acid-rich extract from chicory seeds improves glycemia, atherogenic index, and antioxidant status in rats.
PubMed:Investigation of isomeric transformations of chlorogenic acid in buffers and biological matrixes by ultraperformance liquid chromatography coupled with hybrid quadrupole/ion mobility/orthogonal acceleration time-of-flight mass spectrometry.
PubMed:Identification of phenolic components in dried spices and influence of irradiation.
PubMed:New insights into an ancient antibrowning agent: formation of sulfophenolics in sodium hydrogen sulfite-treated potato extracts.
PubMed:Characterization and quantification of hydroxycinnamate derivatives in Stevia rebaudiana leaves by LC-MSn.
PubMed:Two new antioxidant malonated caffeoylquinic acid isomers in fruits of wild eggplant relatives.
PubMed:Two-dimensional 1H-13C nuclear magnetic resonance (NMR)-based comprehensive analysis of roasted coffee bean extract.
PubMed:Hydrolysis influence on phytochemical composition, antioxidant activity, plasma concentration, and tissue distribution of hydroethanolic Ilex paraguariensis extract components.
PubMed:Caffeoylquinic acid derived free radicals identified during antioxidant reactions of bitter tea (Ilex latifolia and Ilex kudincha).
PubMed:Identification and characterization of five new classes of chlorogenic acids in burdock (Arctium lappa L.) roots by liquid chromatography/tandem mass spectrometry.
PubMed:Antioxidative caffeoylquinic acids and flavonoids from Hemerocallis fulva flowers.
PubMed:Inhibitory effect of caffeic acid on human organic anion transporters hOAT1 and hOAT3: a novel candidate for food-drug interaction.
PubMed:Rapid identification and evaluation of antioxidant compounds from extracts of Petasites japonicus by hyphenated-HPLC techniques.
PubMed:Metabolic fingerprinting reveals differences between shoots of wild and cultivated carrot (Daucus carota L.) and suggests maternal inheritance or wild trait dominance in hybrids.
PubMed:Flavanols from green tea and phenolic acids from coffee: critical quantitative evaluation of the pharmacokinetic data in humans after consumption of single doses of beverages.
PubMed:Neuroprotective effect of caffeoylquinic acids from Artemisia princeps Pampanini against oxidative stress-induced toxicity in PC-12 cells.
PubMed:Analysis of eleven phenolic compounds including novel p-coumaroyl derivatives in lettuce (Lactuca sativa L.) by ultra-high-performance liquid chromatography with photodiode array and mass spectrometry detection.
PubMed:First chemical synthesis and in vitro characterization of the potential human metabolites 5-o-feruloylquinic acid 4'-sulfate and 4'-O-glucuronide.
PubMed:Colonic availability of polyphenols and D-(-)-quinic acid after apple smoothie consumption.
PubMed:Intestinal transit and systemic metabolism of apple polyphenols.
PubMed:Thermal stability of 5-o-caffeoylquinic acid in aqueous solutions at different heating conditions.
PubMed:Antiproliferation effect of commercially brewed coffees on human ovarian cancer cells in vitro.
PubMed:Polyphenols-rich Vernonia amygdalina shows anti-diabetic effects in streptozotocin-induced diabetic rats.
PubMed:Profiling and characterisation by liquid chromatography/multi-stage mass spectrometry of the chlorogenic acids in Gardeniae Fructus.
PubMed:Enantioseparation of DL-isocitric acid by a chiral ligand exchange CE with Ni(II)-D-quinic acid system.
PubMed:New 5-O-caffeoylquinic acid derivatives in fruit of the wild eggplant relative Solanum viarum.
PubMed:Geographical and climatic dependencies of green tea (Camellia sinensis) metabolites: a (1)H NMR-based metabolomics study.
PubMed:Rapid determination of caffeoylquinic acid derivatives in Cynara scolymus L. by ultra-fast liquid chromatography/tandem mass spectrometry based on a fused core C18 column.
PubMed:Isolation and identification of antioxidant compounds from Ligularia fischeri.
PubMed:Coffee constituents as modulators of Nrf2 nuclear translocation and ARE (EpRE)-dependent gene expression.
PubMed:Antioxidant effectiveness of coffee extracts and selected constituents in cell-free systems and human colon cell lines.
PubMed:Isolation and quantitative analysis of peroxynitrite scavengers from Artemisia princeps var. orientalis.
PubMed:Phenolic acids and methylxanthines composition and antioxidant properties of mate (Ilex paraguariensis) residue.
PubMed:Formation of volatile chemicals from thermal degradation of less volatile coffee components: quinic acid, caffeic acid, and chlorogenic acid.
PubMed:Identifications of inhibitors of IgE production by human lymphocytes isolated from 'Cha Chuukanbohon Nou 6' tea leaves.
PubMed:Anti-ulcerogenic effect and HPLC analysis of the caffeoylquinic acid-rich extract from Ligularia stenocephala.
PubMed:Quantitative studies on the influence of the bean roasting parameters and hot water percolation on the concentrations of bitter compounds in coffee brew.
PubMed:Global regulation of food supply by Pseudomonas putida DOT-T1E.
PubMed:Acids, sugars, and sugar alcohols in Chinese hawthorn (Crataegus spp.) fruits.
PubMed:Angiostatic effects of Brazilian green propolis and its chemical constituents.
PubMed:Chemical kinetics of 5-o-caffeoylquinic acid in superheated steam: effect of isomerization on mate (Ilex paraguariensis) manufacturing.
PubMed:Application of metabolomics in the analysis of manufacturing type of pu-erh tea and composition changes with different postfermentation year.
PubMed:Kinetic analysis and mechanism on the inhibition of chlorogenic acid and its components against porcine pancreas alpha-amylase isozymes I and II.
PubMed:Ficus carica L.: Metabolic and biological screening.
PubMed:A novel method for the quantification of quinic acid in food using stable isotope dilution analysis.
PubMed:Metabolic profile of the bioactive compounds of burdock (Arctium lappa) seeds, roots and leaves.
PubMed:Effects of latitude and weather conditions on contents of sugars, fruit acids, and ascorbic acid in black currant (Ribes nigrum L.) juice.
PubMed:Organic acids composition of Cydonia oblonga Miller leaf.
PubMed:Elucidation of the mechanism of enzymatic browning inhibition by sodium chlorite.
PubMed:Identification of hydroxycinnamoylquinic acids of arnica flowers and burdock roots using a standardized LC-DAD-ESI/MS profiling method.
PubMed:Structure determination of 3-O-caffeoyl-epi-gamma-quinide, an orphan bitter lactone in roasted coffee.
PubMed:Identification of the antimicrobial substances produced by Solanum palinacanthum (Solanaceae).
PubMed:Effects of different cooking methods on antioxidant profile, antioxidant capacity, and physical characteristics of artichoke.
PubMed:Stress-induced biosynthesis of dicaffeoylquinic acids in globe artichoke.
PubMed:Roasting effects on formation mechanisms of coffee brew melanoidins.
PubMed:Analysis of expressed sequence tags from Actinidia: applications of a cross species EST database for gene discovery in the areas of flavor, health, color and ripening.
PubMed:Phenolic antioxidants from green tea produced from Camellia taliensis.
PubMed:Electron spin resonance (ESR) studies on the formation of roasting-induced antioxidative structures in coffee brews at different degrees of roast.
PubMed:Low molecular weight melanoidins in coffee brew.
PubMed:5-caffeoylquinic acid and caffeic acid down-regulate the oxidative stress- and TNF-alpha-induced secretion of interleukin-8 from Caco-2 cells.
PubMed:Human glycemic response and phenolic content of unsweetened cranberry juice.
PubMed:Antiviral activities of coffee extracts in vitro.
PubMed:Antioxidant properties of sour cherries (Prunus cerasus L.): role of colorless phytochemicals from the methanolic extract of ripe fruits.
PubMed:Incorporation of chlorogenic acids in coffee brew melanoidins.
PubMed:Impact of fermentation on phenolic compounds in leaves of pak choi (Brassica campestris L. ssp. chinensis var. communis) and Chinese leaf mustard (Brassica juncea coss).
PubMed:Polyphenols are intensively metabolized in the human gastrointestinal tract after apple juice consumption.
PubMed:Changes in polyphenolic content and radical-scavenging activity of sweet potato (Ipomoea batatas L.) during storage at optimal and low temperatures.
PubMed:Phenolic antioxidants identified by ESI-MS from Yerba maté (Ilex paraguariensis) and green tea (Camelia sinensis) extracts.
PubMed:Identification of flavonoids and hydroxycinnamic acids in pak choi varieties (Brassica campestris L. ssp. chinensis var. communis) by HPLC-ESI-MSn and NMR and their quantification by HPLC-DAD.
PubMed:Formation of the thiocyanate conjugate of chlorogenic acid in coffee under acidic conditions in the presence of thiocyanate and nitrite: possible occurrence in the stomach.
PubMed:[Simultaneous determination of twenty-one organic acids in food by ion chromatography with eluent autogeneration].
PubMed:Enhancing the oxidative stability of rice crackers by addition of the ethanolic extract of phytochemicals from Cratoxylum formosum Dyer.
PubMed:Profiling and characterization by LC-MSn of the galloylquinic acids of green tea, tara tannin, and tannic acid.
PubMed:Hepatoprotective and antioxidative effects of total phenolics from Laggera pterodonta on chemical-induced injury in primary cultured neonatal rat hepatocytes.
PubMed:Profiling the chlorogenic acids and other caffeic acid derivatives of herbal chrysanthemum by LC-MSn.
PubMed:Quantitative precursor studies on di- and trihydroxybenzene formation during coffee roasting using "in bean" model experiments and stable isotope dilution analysis.
PubMed:Profiling the chlorogenic acids of aster by HPLC-MS(n).
PubMed:Quantitative determination of phenolic compounds in artichoke-based dietary supplements and pharmaceuticals by high-performance liquid chromatography.
PubMed:New polyphenol derivative in Ipomoea batatas tubers and its antioxidant activity.
PubMed:Changes in organic acids and sugars during early stages of development of acidic and acidless citrus fruit.
PubMed:Alpha-glucosidase inhibitory and antihyperglycemic effects of polyphenols in the fruit of Viburnum dilatatum Thunb.
PubMed:Characterization by LC-MS(n) of four new classes of p-coumaric acid-containing diacyl chlorogenic acids in green coffee beans.
PubMed:Anti-human immunodeficiency virus activity of 3,4,5-tricaffeoylquinic acid in cultured cells of lettuce leaves.
PubMed:Fast analysis of sugars, fruit acids, and vitamin C in sea buckthorn (Hippophaë rhamnoides L.) varieties.
PubMed:Characterization by LC-MS(n) of four new classes of chlorogenic acids in green coffee beans: dimethoxycinnamoylquinic acids, diferuloylquinic acids, caffeoyl-dimethoxycinnamoylquinic acids, and feruloyl-dimethoxycinnamoylquinic acids.
PubMed:Anti-hyperglycemic Potential of Natural Products.
PubMed:Tungtungmadic acid, a novel antioxidant, from Salicornia herbacea.
PubMed:Discriminating between the six isomers of dicaffeoylquinic acid by LC-MS(n).
PubMed:Screening of raw coffee for thiol binding site precursors using "in bean" model roasting experiments.
PubMed:Antioxidant properties of prunes (Prunus domestica L.) and their constituents.
PubMed:A new glucosyl feruloyl quinic acid as a potential marker for roots and rhizomes of goldenseal, Hydrastis canadensis.
PubMed:Characterization of cigarette tobacco by direct electrospray ionization-ion trap mass spectrometry (ESI-ITMS) analysis of the aqueous extract--a novel and simple approach.
PubMed:Deodorization with ku-ding-cha containing a large amount of caffeoyl quinic acid derivatives.
PubMed:Identification and quantification of caffeoylquinic acids and flavonoids from artichoke (Cynara scolymus L.) heads, juice, and pomace by HPLC-DAD-ESI/MS(n).
PubMed:HPLC-MSn analysis of phenolic compounds and purine alkaloids in green and black tea.
PubMed:In vitro and ex vivo antihydroxyl radical activity of green and roasted coffee.
PubMed:Metabolite profiling using (1)H NMR spectroscopy for quality assessment of green tea, Camellia sinensis (L.).
PubMed:Inhibition of apple polyphenol oxidase activity by procyanidins and polyphenol oxidation products.
PubMed:Changes in broccoli (Brassica oleracea L. Var. italica) health-promoting compounds with inflorescence development.
PubMed:Health-promoting compounds in broccoli as influenced by refrigerated transport and retail sale period.
PubMed:Hierarchical scheme for LC-MSn identification of chlorogenic acids.
PubMed:Quantitative evaluation of antioxidant components in prunes (Prunus domestica L.).
PubMed:Hydrophilic carboxylic acids and iridoid glycosides in the juice of American and European cranberries (Vaccinium macrocarpon and V. oxycoccos), lingonberries (V. vitis-idaea), and blueberries (V. myrtillus).
PubMed:LC/MS/MS characterization of phenolic constituents in dried plums.
PubMed:Inhibitory effects of plant phenols on the activity of selected enzymes.
PubMed:Study of the organic acids composition of quince (Cydonia oblonga Miller) fruit and jam.
PubMed:Processing effects on the composition of sea buckthorn juice from Hippophae rhamnoides L. Cv. Indian Summer.
PubMed:Direct chiral resolution of tartaric acid in food products by ligand exchange capillary electrophoresis using copper(II)-D-quinic acid as a chiral selector.
PubMed:Identification and antioxidant activity of novel chlorogenic acid derivatives from bamboo (Phyllostachys edulis).
PubMed:Isolation and characterization of human colonic bacteria able to hydrolyse chlorogenic acid.
PubMed:Stability and bioavailability of antioxidants in garland (Chrysanthemum coronarium L.).
PubMed:Stabilization of soybean oil with heated quercetin and 5-caffeoylquinic acid in the presence of ferric ion.
PubMed:Thermodynamics of interaction of caffeic acid and quinic acid with multisubunit proteins.
PubMed:Interaction of 3'-O-caffeoyl D-quinic acid with human serum albumin.
PubMed:A comparative genotoxicity study of chlorogenic acid (3-0-caffeoylquinic acid).
PubMed:Bound quinic acid as a measure of coupling of leaf and sunflower-seed proteins with chlorogenic acid congeners: loss of availability of lysine.
PubMed:Identification and quantitative analysis of sugars and non-volatile organic acids in Chinese gooseberry fruit (Actinidia chinensis Planch.).
PubMed:Determination of organic acids in foods by liquid chromatography.
PubMed:(-)-3t,4t-Dihydroxycyclohexane-1c-carboxylate, a new quinate metabolite of Lactobacillus plantarum.
PubMed:The metabolism of certain drugs and food chemicals in man.
PubMed:Symposium on microbial changes in foods. Microbiological aspects of production and spoilage of cider.
PubMed:Phenolic and sugar components of Armavirec variety sunflower (Helianthus annuus) seed meal.
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