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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 474.81 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 426.00 °F. TCC ( 219.00 °C. ) (est)
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| logP (o/w): | 4.218 (est) |
| Soluble in: |
| | water, 18.61 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for panaxytriol usage levels up to: | | | not for fragrance use.
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| Recommendation for panaxytriol flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | heptadec-1-en-4,6-diyne-3,9,10-triol | | 1- | heptadecene-4,6-diyne-3,9,10-triol |
Articles:
| PubMed:Network pharmacology analyses of the antithrombotic pharmacological mechanism of Fufang Xueshuantong Capsule with experimental support using disseminated intravascular coagulation rats. |
| PubMed:Direct and comprehensive analysis of ginsenosides and diterpene alkaloids in Shenfu injection by combinatory liquid chromatography-mass spectrometric techniques. |
| PubMed:[Chemical constituents from stems of Cistanche deserticola cultured in Tarim desert]. |
| PubMed:Identification of the active components in Shenmai injection that differentially affect Cyp3a4-mediated 1'-hydroxylation and 4-hydroxylation of midazolam. |
| PubMed:Multifaceted cytoprotection by synthetic polyacetylenes inspired by the ginseng-derived natural product, panaxytriol. |
| PubMed:(3R, 9R, 10R)-Panaxytriol: A molecular-based nutraceutical with possible application to cancer prevention and treatment. |
| PubMed:Induction of chemoprotective phase 2 enzymes by ginseng and its components. |
| PubMed:Imaging induction of cytoprotective enzymes in intact human cells: coumberone, a metabolic reporter for human AKR1C enzymes reveals activation by panaxytriol, an active component of red ginseng. |
| PubMed:Polyacetylenes from the roots of cultivated-wild ginseng and their cytotoxicity in vitro. |
| PubMed:Total synthesis of (3R,9R,10R)-panaxytriol via tandem metathesis and metallotropic [1,3]-shift as a key step. |
| PubMed:Total synthesis as a resource in drug discovery: the first in vivo evaluation of panaxytriol and its derivatives. |
| PubMed:Straightforward synthesis of panaxytriol: an active component of Red Ginseng. |
| PubMed:Chemoenzymatic asymmetric total syntheses of antitumor agents (3R,9R,10R)- and (3S,9R,10R)-Panaxytriol and (R)- and (S)-Falcarinol from Panax ginseng using an enantioconvergent enzyme-triggered cascade reaction. |
| PubMed:Gymnasterkoreaynes A-F, cytotoxic polyacetylenes from Gymnaster koraiensis. |
| PubMed:Inhibitory effect of tumor cell proliferation and induction of G2/M cell cycle arrest by panaxytriol. |
| PubMed:Absolute structure of panaxytriol. |
| PubMed:In vitro anti-Helicobacter pylori activity of panaxytriol isolated from ginseng. |
| PubMed:Inducible nitric oxide synthase inhibitors from Saposhnikovia divaricata and Panax quinquefolium. |
| PubMed:Antiproliferative constituents in Umbelliferae plants II. Screening for polyacetylenes in some Umbelliferae plants, and isolation of panaxynol and falcarindiol from the root of Heracleum moellendorffii. |
| PubMed:Polyacetylene analogs, isolated from hairy roots of Panax ginseng, inhibit Acyl-CoA : cholesterol acyltransferase. |
| PubMed:[Polyacetylene compounds from Panax notoginsenoside]. |
| PubMed:Screening of polyacetylenic alcohols in crude drugs using the ELISA for panaxytriol. |
| PubMed:A possible mechanism for the cytotoxicity of a polyacetylenic alcohol, panaxytriol: inhibition of mitochondrial respiration. |
| PubMed:A highly sensitive enzyme-linked immunosorbent assay (ELISA) for antitumor polyacetylenic alcohol, panaxytriol. |
| PubMed:Potentiation of cytotoxicity of mitomycin C by a polyacetylenic alcohol, panaxytriol. |
| PubMed:The first specific antibody against cytotoxic polyacetylenic alcohol, panaxynol. |
| PubMed:[Thin layer chromatography and extractive technology of Panax japonicum C.A. Mey. var. major (Burk.) C. Y. Wu et K. M. Feng growing in Qingba Mountain Area]. |
| PubMed:Cytotoxic activity of polyacetylene compounds in Panax ginseng C. A. Meyer. |
| PubMed:[Cell growth inhibitory substance isolated from Panax ginseng root: panaxytriol]. |
| PubMed:Determination of panaxytriol, a new type of tumour growth inhibitor from Panax ginseng, by capillary gas chromatography. |
| PubMed:Studies on the panaxytriol of Panax ginseng C. A. Meyer. Isolation, determination and antitumor activity. |
| PubMed:[A tumor inhibitory substance from panax ginseng]. |
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3D/inchi