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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 65.00 to 66.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 66.00 to 67.00 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 72.700000 mmHg (est) |
| Flash Point: | -5.00 °F. TCC ( -20.60 °C. ) (est)
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| logP (o/w): | 2.157 (est) |
| Soluble in: |
| | alcohol | | | water, 3030 mg/L @ 25 °C (est) |
| Insoluble in: |
| | water |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
inhalation-rat LC50 6651 mg/m3/1H
Experimental and Molecular Pathology. Vol. 39, Pg. 342, 1983.
inhalation-mouse LC50 3022 mg/m3/1H
Toxicology and Applied Pharmacology. Vol. 72, Pg. 124, 1984.
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for 3-methyl furan usage levels up to: | | | not for fragrance use.
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| Recommendation for 3-methyl furan flavor usage levels up to: |
| | not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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Risks for public health related to the presence of furan and methylfurans in food
View page or View pdf
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Identifying and collecting relevant literature related to the oral toxicity of furan and its methyl analogues, 2-methylfuran and 3-methylfuran
View page or View pdf
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| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :13587 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| 3-methylfuran |
| Chemidplus:0000930278 |
| RTECS:LU2630000 for cas# 930-27-8 |
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | furan, 3-methyl- | | 3- | methylfuran |
Articles:
| PubMed:Avenaol, a germination stimulant for root parasitic plants from Avena strigosa. |
| PubMed:Products of the OH radical-initiated reactions of furan, 2- and 3-methylfuran, and 2,3- and 2,5-dimethylfuran in the presence of NO. |
| PubMed:Structural effects on persister control by brominated furanones. |
| PubMed:Volatile emissions from Mycobacterium avium subsp. paratuberculosis mirror bacterial growth and enable distinction of different strains. |
| PubMed:(Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one sensitizes Escherichia coli persister cells to antibiotics. |
| PubMed:Controlling persister cells of Pseudomonas aeruginosa PDO300 by (Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one. |
| PubMed:Airborne molds and bacteria, microbial volatile organic compounds (MVOC), plasticizers and formaldehyde in dwellings in three North European cities in relation to sick building syndrome (SBS). |
| PubMed:Reverting antibiotic tolerance of Pseudomonas aeruginosa PAO1 persister cells by (Z)-4-bromo-5-(bromomethylene)-3-methylfuran-2(5H)-one. |
| PubMed:New branching inhibitors and their potential as strigolactone mimics in rice. |
| PubMed:Simple indole alkaloids from the neotropical rutaceous tree Raputia simulans. |
| PubMed:Kinetics of the reactions of OH radicals with 2- and 3-methylfuran, 2,3- and 2,5-dimethylfuran, and E- and Z-3-hexene-2,5-dione, and products of OH + 2,5-dimethylfuran. |
| PubMed:Purification of polar compounds from Radix isatidis using conventional C18 column coupled with polar-copolymerized C18 column. |
| PubMed:Development of an analytical method and survey of foods for furan, 2-methylfuran and 3-methylfuran with estimated exposure. |
| PubMed:Density functional theory and RRKM calculations of the gas-phase unimolecular rearrangements of methylfuran and pyran ions before fragmentations. |
| PubMed:Analysis of exhaled breath from smokers, passive smokers and non-smokers by solid-phase microextraction gas chromatography/mass spectrometry. |
| PubMed:Microbial volatile organic compounds in the air of moldy and mold-free indoor environments. |
| PubMed:Detection of fungal development in closed spaces through the determination of specific chemical targets. |
| PubMed:A theoretical study of the photochemical isomerization reactions of furans from the triplet state. |
| PubMed:Indoor molds, bacteria, microbial volatile organic compounds and plasticizers in schools--associations with asthma and respiratory symptoms in pupils. |
| PubMed:Acute effects of a fungal volatile compound. |
| PubMed:A possible mechanism for furan formation in the tropospheric oxidation of dienes. |
| PubMed:Monitoring OH-initiated oxidation kinetics of isoprene and its products using online mass spectrometry. |
| PubMed:A concise synthesis of siphonodictidine. |
| PubMed:Mechanism of stereo- and regioselectivity in the Paternò-Büchi reaction of furan derivatives with aromatic carbonyl compounds: importance of the conformational distribution in the intermediary triplet 1,4-diradicals. |
| PubMed:Simultaneous enantioseparation of flobufen and its diastereomeric metabolites on ULMO, a Pirkle type chiral stationary phase. |
| PubMed:Fungal volatiles as indicators of food and feeds spoilage. |
| PubMed:Synthesis and MAO-B substrate properties of 1-methyl-4-heteroaryl-1,2,3,6-tetrahydropyridines. |
| PubMed:Pulmonary reactions after exposure to 3-methylfuran vapour, a fungal metabolite. |
| PubMed:Identification of volatile metabolites from five fungal species cultivated on two media. |
| PubMed:Effect of crop development on biogenic emissions from plant populations grown in closed plant growth chambers. |
| PubMed:In vitro antitumor activity of fused 2-carboxaldehyde N,N-dimethylhydrazone-3-methylfuran derivatives. |
| PubMed:Volatile metabolites produced by six fungal species compared with other indicators of fungal growth on cereal grains. |
| PubMed:Nonneoplastic changes in the olfactory epithelium--experimental studies. |
| PubMed:Long-term effects of repeated exposure to 3-methylfuran in hamsters and mice. |
| PubMed:Synthesis and evaluation of furan, thiophene, and azole bis[(carbamoyloxy)methyl] derivatives as potential antineoplastic agents. |
| PubMed:Toxicity-distribution relationships among 3-alkylfurans in mouse liver and kidney. |
| PubMed:Reactive metabolites from the bioactivation of toxic methylfurans. |
| PubMed:The effect of 3-methylfuran inhalation exposure on the rat nasal cavity. |
| PubMed:Toxicity-distribution relationships among 3-alkylfurans in the mouse lung. |
| PubMed:Acute inhalation toxicity of 3-methylfuran in the mouse: pathology, cell kinetics, and respiratory rate effects. |
| PubMed:Metabolic basis for the pulmonary Clara cell as a target for pulmonary carcinogenesis. |
| PubMed:Pathology of acute inhalation exposure to 3-methylfuran in the rat and hamster. |
| PubMed:Pulmonary bronchiolar alkylation and necrosis by 3-methylfuran, a naturally occurring potential atmospheric contaminant. |
| PubMed:Steam volatile aroma constituents of roasted coffee: neutral fraction. |
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3D/inchi