EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

tetrahydroxyethyl ethylenediamine
ethylenediamine, N,N,N',N'-tetrakis(2-hydroxyethyl)-

Supplier Sponsors

CAS Number: 140-07-8Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:205-396-0
Nikkaji Web:J138.064H
Beilstein Number:1767829
XlogP3-AA:-2.40 (est)
Molecular Weight:236.31208000
Formula:C10 H24 N2 O4
NMR Predictor:Predict (works with chrome or firefox)
Category:buffering agents, sequestrants
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
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Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: buffering agents
chelating agents
Santa Cruz Biotechnology
For experimental / research use only.
Sigma-Aldrich: Aldrich
For experimental / research use only.
For experimental / research use only.
N,N,N',N'-Tetrakis(2-hydroxyethyl)ethylenediamine >50.0%(GC)
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
Safety in Use Information:
buffering agents, sequestrants
Recommendation for tetrahydroxyethyl ethylenediamine usage levels up to:
 not for fragrance use.
Recommendation for tetrahydroxyethyl ethylenediamine flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
EPA Substance Registry Services (TSCA):140-07-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :67322
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:140-07-8
Pubchem (cid):67322
Pubchem (sid):135023585
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2922.19.9590
Potential Blenders and core components note
None Found
Potential Uses:
 buffering agents
Occurrence (nature, food, other):note
 not found in nature
 ethanol, 2,2',2'',2'''-(1,2-ethanediyldinitrilo)tetrakis-
2,2',2'',2'''-ethylene dinitrilotetraethanol
 ethylenediamine tetraethanol
 ethylenediamine, N,N,N',N'-tetrakis(2-hydroxyethyl)-
 tetrahydroxyethyl ethylene diamine


PubMed:New Tetracopper(II) Cubane Cores Driven by a Diamino Alcohol: Self-assembly Synthesis, Structural and Topological Features, and Magnetic and Catalytic Oxidation Properties.
PubMed:The coordination chemistry and magnetism of some 3d-4f and 4f amino-polyalcohol compounds.
PubMed:Low density biodegradable shape memory polyurethane foams for embolic biomedical applications.
PubMed:Synthesis and structural characterization of group 4 metal alkoxide complexes of N,N,N',N'-tetrakis(2-hydroxyethyl)ethylenediamine and their use as initiators in the ring-opening polymerization (ROP) of rac-lactide under industrially relevant conditions.
PubMed:DFT studies of structural and some spectral parameters of copper(II) complexes with N,N,N',N″-tetrakis (2-hydroxyethyl/propyl) ethylenediamine and tris(2-hydroxyethyl)amine.
PubMed:High symmetry superoctahedron cluster [Mn(III)18O14]26+ from the use of N,N,N',N'-tetrakis(2-hydroxyethyl)ethylenediamine.
PubMed:New mixed-valent Mn clusters from the use of N,N,N',N'-tetrakis(2-hydroxyethyl)ethylenediamine (edteH4): Mn3, Mn4, Mn6, and Mn10.
PubMed:Family of double-cubane Mn4Ln2 (Ln = Gd, Tb, Dy, Ho) and Mn4Y2 complexes: a new Mn4Tb2 single-molecule magnet.
PubMed:Effect of hydroxyl and amino groups on electrochemiluminescence activity of tertiary amines at low tris(2,2'-bipyridyl)ruthenium(II) concentrations.
PubMed:High-spin tetranuclear Mn(II)(2)Mn(IV)(2) clusters with unique Mn(ii)-Mn(iv) magnetic exchange: synthesis, structures and magnetism.
PubMed:Unusual structural types in polynuclear iron chemistry from the use of N,N,N',N'-tetrakis(2-hydroxyethyl)ethylenediamine (edteH4): Fe5, Fe6, and Fe12 clusters.
PubMed:Unusual structural types in manganese cluster chemistry from the use of N,N,N',N'-tetrakis(2-hydroxyethyl)ethylenediamine: Mn8, Mn12, and Mn20 Clusters.
PubMed:New Mn12 clusters with tunable oxidation states via the use of N,N,N',N'-tetrakis(2-hydroxyethyl)ethylenediamine.
PubMed:Functional and structural study on chelator-induced suppression of S2/S1 FTIR spectrum in photosynthetic oxygen-evolving complex.
PubMed:Formation of two diverse classes of poly(amino-alkoxide) chelates and their mononuclear and polynuclear lanthanide(III) complexes.
PubMed:Metal complexes of tetrapodal ligands: synthesis, spectroscopic and thermal studies, and X-ray crystal structure studies of Na(I), Ca(II), Sr(II), and Ba(II) complexes of tetrapodal ligands N,N,N',N'-tetrakis(2-hydroxypropyl)ethylenediamine and N,N,N',N'-tetrakis(2-hydroxyethyl)ethylenediamine.
None found
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