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Category:information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | crystals colorless or white (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 104.00 °C. @ 760.00 mm Hg
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| Soluble in: |
| | water, 0.006592 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
|
Not determined
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Safety in Use Information:
| Category: | | information only not used for fragrances or flavors |
| Recommendation for diethyl stilbestrol dipropionate usage levels up to: | | | not for fragrance use.
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| |
| Recommendation for diethyl stilbestrol dipropionate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | [4-[(E)-4-(4-propanoyloxyphenyl)hex-3-en-3-yl]phenyl] propanoate |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 657220 |
| Pubchem (sid): | 134973202 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| trans-4,4'-(1,2- | diethyl-1,2-ethene diyl) bisphenol dipropionate | | alpha,alpha'- | diethyl-4,4'-stilbene diol dipropionyl ester | | p,p'- | dipropionoxy-trans-alpha,beta-diethyl stilbene | | | estilben | | | estrostilben | | | horfemine | | | pabestrol D | | | sinciclan | | | sinestrol | | | stilbestrol dipropionate | | | stilbestrol propionate | | | stilbestronate | | | stilbofax | | | synestrol | | | vetoestrol | | | willestrol | | [4-[(E)-4-(4- | propanoyloxyphenyl)hex-3-en-3-yl]phenyl] propanoate |
Articles:
| PubMed:A proline rich acidic protein PRAP identified from uterine luminal fluid of estrous mice is able to enhance the estrogen responsiveness of Ishikawa cells. |
| PubMed:[Prognostic factors for estrogen therapy of relapsed prostate cancer after maximal androgen blockade (MAB)]. |
| PubMed:[Combination chemotherapy with docetaxel and cisplatin in patients with hormone-refractory prostate cancer]. |
| PubMed:Phase III study of combined chemohormonal therapy in metastatic prostate cancer (ECOG 3882): an Eastern Cooperative Oncology Group study. |
| PubMed:Potential estrogenic and antiestrogenic activity of the cyclic siloxane octamethylcyclotetrasiloxane (D4) and the linear siloxane hexamethyldisiloxane (HMDS) in immature rats using the uterotrophic assay. |
| PubMed:Effect of diethylstilbestrol (DES) on intracellular Ca(2+) levels in renal tubular cells. |
| PubMed:Morphometric studies on the testes of rats treated neonatally with oestrogen and subsequently with gonadotrophins and testosterone. |
| PubMed:Uterotrophic assay of two concentrations of migrates from each of 23 polystyrenes administered orally (by gavage) to immature female Wistar rats. |
| PubMed:The effects of diethylstilbestrol (DES) before birth on the development of masculine behavior in juvenile female rhesus monkeys. |
| PubMed:Immunohistochemical method for detecting lesions in the prostate gland of bulls treated with diethylstilbestrol-dipropionate. |
| PubMed:Detection of the centromere in micronuclei by fluorescence in situ hybridization: its application to the human lymphocyte micronucleus assay after treatment with four suspected aneugens. |
| PubMed:Detection of aneuploidy-inducing carcinogens in the Syrian hamster embryo (SHE) cell transformation assay. |
| PubMed:Follicular growth patterns in the house rat (Rattus rattus). |
| PubMed:Analysis of the six additional chemicals for in vitro assays of the European Economic Communities' EEC aneuploidy programme using Saccharomyces cerevisiae D61.M and the in vitro porcine brain tubulin assembly assay. |
| PubMed:Effect of diethylstilbestrol and related compounds on the Ca(2+)-transporting ATPase of sarcoplasmic reticulum. |
| PubMed:Changing cytokeratin expression patterns in diethylstilbestrol dipropionate-induced metaplastic lesions of the goat prostate. |
| PubMed:Standardized kinetic microassay to quantify differential chemosensitivity on the basis of proliferative activity. |
| PubMed:Comparison of pharmacotherapeutic procedures in the treatment of sexual deviant behaviour. |
| PubMed:Detection of induced mitotic chromosome loss in Saccharomyces cerevisiae--an interlaboratory assessment of 12 chemicals. |
| PubMed:[The mechanisms of the decrease in prostatic mass in rats during the administration of estrogenic preparations into the cerebrospinal fluid]. |
| PubMed:Application of diethylstilbestrol dipropionate in bulls. II. Residues in bile, liver, kidney, muscle tissues and application site. |
| PubMed:Application of diethylstilbestrol dipropionate in bulls. I. Excretion of residues in urine and faeces and histological and immunohistochemical changes in the prostate. |
| PubMed:[Rationale for sinestrol therapy of cancer of the larynx]. |
| PubMed:Isolation and typing of a strain of Chlamydia psittaci from Angora goats. |
| PubMed:Methods of analysis of data on mitotic aneuploidy. |
| PubMed:[Suppression of unwanted lactation in parturients with estrogens and bromocriptine]. |
| PubMed:Metabolism of diethylstilbestrol by horseradish peroxidase and prostaglandin-H synthase. Generation of a free radical intermediate and its interaction with glutathione. |
| PubMed:Estrogens before birth and development of sex-related reproductive traits in the female guinea pig. |
| PubMed:Effects of diethylstilboestrol-dipropionate on SCEs, micronuclei, cytotoxicity, aneuploidy and cell proliferation in maternal and foetal mouse cells treated in vivo. |
| PubMed:Genesis of oestrogenic inhibition of soleus muscle development in female mice. |
| PubMed:Induction of vitellogenesis in Japanese quail as a sensitive indicator of the estrogen-mimetic effect of a variety of environmental contaminants. |
| PubMed:[Effect of central and peripheral estrogen administration on the indices of immune homeostasis]. |
| PubMed:Effect of stilboestrol dipropionate on the rate of spermatogenesis in KP and C57 mice and in their hybrids. |
| PubMed:[Comparative studies of hormonal methods for affecting the reproductive functions of cows being raised by different technics]. |
| PubMed:[Comparative study of the effectiveness of various doses of estrogens after their "central" and "peripheral" administration]. |
| PubMed:Nuclear diameter in the anterior pituitary gland of the rat: effects of estrogen, bromocriptine, and haloperidol. |
| PubMed:[Model study for the determination of retention following intramuscular administration of a crystalline suspension of diethylstilbestrol to fattening calves]. |
| PubMed:[Chromosome aberrations and sister chromatid exchanges in a human lymphocyte culture exposed to diethylstilbestrol dipropionate]. |
| PubMed:Update on the relation of herpesvirus hominis type II to carcinoma of the cervix. |
| PubMed:Massive pleural effusions from prostatic lymphangitic carcinomatosis: resolution with endocrine therapy. |
| PubMed:[Therapy in estrogen deficiency of the vagina]. |
| PubMed:[Carbohydrate and fat metabolic state in female rats subjected to transplacental diethylstilbestrol exposure]. |
| PubMed:[Effectiveness of depressing milk secretion in clinical forms of suppurative puerperal mastitis]. |
| PubMed:[Effect of administration of ethyl alcohol on the structure of the anterior pituitary of albino rats treated with estrogens, testosterone and gonadotropin]. |
| PubMed:Study on serotoninergic mechanisms of compensatory ovarian hypertrophy in rats. |
| PubMed:The inhibition of the transplacental blastomogenic effect of nitrosomethylurea by postnatal administration of buformin to rats. |
| PubMed:Tetrazolium salts in pharmaceutical analysis II: direct assay of diethylstilbestrol and diethylstilbestrol dipropionate. |
| PubMed:Diethylstilboestrol and diethylstilboestrol dipropionate. |
| PubMed:Application of synthetic estrogen in sheep. |
| PubMed:Hematology of Japanese quail treated with exogenous stilbestrol dipropionate and testosterone propionate. |
| PubMed:Effect of stilbestrol dipropionate on egg production and growth of reproductive organs in poultry. |
| PubMed:[Histochemical changes in the hypothalamo-pituitary system of a newborn rat following introduction of a single dose of stilbestrol dipropionate]. |
| PubMed:Vitellogenesis in Bidderian oocytes after diethylstilbestrol dipropionate treatment on Bufo bufo adult males. |
| PubMed:[Periods of obtainment of palatine clefts with diethylstilbestrol dipropionate in mice]. |
| PubMed:[Effect of a single dose of stilbestrol dipropionate, LH and testosterone propionate on the insterstitial cells of the rat testis]. |
| PubMed:[Effect of cyproterone (androgen antagonist) and stilbestrol dipropionate on the rat testis]. |
| PubMed:[Effect of single doses of stilbestrol dipropionate, LH and testosterone on the structure and function of seminal vesicles in rats]. |
| PubMed:[Hormone treatment in women with breast cancer. I. Effect of diethylstilbestrol dipropionate on the clinical course and on the excretion of estrogen in the urine of women with metastatic breast cancer]. |
| PubMed:[Effect of a single dose of stilbestrol dipropionate on the seminal vesicles in the rat]. |
| PubMed:[Extramedullary plasmocytomas. A propos of a case of extramedullary plasmocytoma of the nasal fossae treated with diethylstilbestrol dipropionate]. |
| PubMed:[The effect of stilbestrol dipropionate on some histochemical reactions in the liver of the male rat]. |
| PubMed:[The mechanism of leukopenia caused by antimitotics and the anti-leukopenic effect of diethylstilbestrol dipropionate]. |
| PubMed:NEW and nonofficial remedies: diethylstilbestrol dipropionate. |
| PubMed:Effects of diethylstilbestrol dipropionate upon postpartum changes in the cow. |
| PubMed:[Not Available]. |
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3D/inchi