EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

pepsin A

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CAS Number: 9001-75-6
ECHA EC Number:232-629-3
FDA UNII:GID333S43J
Formula:unspecified
Category:enzyme preparations and microorganisms
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Perfumer and Flavorist:Search
Google Patents:Search
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PubMed:Search
NCBI:Search
JECFA Food Additive: Pepsin from Hog Stomach
FDA Mainterm (SATF):9001-75-6 ; PEPSIN
FDA Regulation:
FDA PART 137 -- CEREAL FLOURS AND RELATED PRODUCTS
Subpart B--Requirements for Specific Standardized Cereal Flours and Related Products
Sec. 137.305 Enriched farina.


FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1595 Pepsin.
 
Physical Properties:
Appearance:pale tan, amber or brown powder, past or liquid (est)
Food Chemicals Codex Listed: No
Soluble in:
 water
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: hair conditioning
skin conditioning
 
Suppliers:
American Laboratories
011Pepsin 1:15,000 Powder
American Laboratories
Pepsin 1:10,000 Granular 006
American Laboratories
Pepsin 1:10,000 Powder 005
American Laboratories
Pepsin 1:10,000 Powder 313
American Laboratories
Pepsin 1:10,000 Powder 859
American Laboratories
Pepsin 1:10,000 Spray Dried Powder 502
American Laboratories
Pepsin 1:15,000 Spray Dried Powder 548
American Laboratories
Pepsin 1:3,000 Powder 001
American Laboratories
Pepsin 1:3000 Powder 547
American Laboratories
Pepsin 1:3000 Powder 860
American Laboratories
Pepsin 1:3000 Technical Grade 484
American Laboratories
Pepsin Full Strength Powder 294
American Laboratories
Pepsin Full Strength Spray Dried Powder 214
American Laboratories
Pepsin Reference 21C
BOC Sciences
For experimental / research use only.
pepsin purified, 1:3000
Glentham Life Sciences
Pepsin
Indis NV
For experimental / research use only.
Pepsin
Penta International
PEPSIN 1:3000
Penta International
PEPSIN 1:10,000 NF
United International
Pepsin
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
enzyme preparations and microorganisms
Recommendation for pepsin A usage levels up to:
 not for fragrance use.
 
Recommendation for pepsin A flavor usage levels up to:
 not for flavor use.
 
Safety References:
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):9001-75-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
Chemidplus:0009001756
 
References:
Pubchem (sid):135274930
 
Other Information:
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
FooDB:FDB018680
FDA Listing of Food Additive Status:View
VCF-Online:VCF Volatile Compounds in Food
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 biological additives
 
Occurrence (nature, food, other):note
 pepsin A
Search PMC Picture
 pepsin fortior
Search PMC Picture
 
Synonyms:
 pepsin fortior
 pepsin, bovine
 

Articles:

PubMed:Synthesis and in vitro antioxidant functions of protein hydrolysate from backbones of Rastrelliger kanagurta by proteolytic enzymes.
PubMed:Viability and resistance of lactobacilli isolated from cocoa fermentation to simulated gastrointestinal digestive steps in soy yogurt.
PubMed:Isolation of Pediococcus acidilactici Kp10 with ability to secrete bacteriocin-like inhibitory substance from milk products for applications in food industry.
PubMed:Improving chocolate flavor in poor-quality cocoa almonds by enzymatic treatment.
PubMed:Stucture of the complex between Mucor pusillus pepsin and the key domain of κ-casein for site-directed mutagenesis: a combined molecular modeling and docking approach.
PubMed:Sucralfate alleviating post-laser-assisted uvulopalatoplasty pain.
PubMed:Sucrose as a sweetener for activated charcoal.
PubMed:Composition of cheddar cheese made with different milk clotting enzymes.
 
Notes:
formed from pig pepsinogen by cleavage of one peptide bond. the enzyme is a single polypeptide chain and is inhibited by methyl 2-diaazoacetamidohexanoate. it cleaves peptides preferentially at the carbonyl linkages of phenylalanine or leucine and acts as the principal digestive enzyme of gastric juice. Used in the preparation of fish meal and other protein hydrolysates and in the manuf. of cheese as a milk-clotting agent Pepsin is an enzyme that is released by the chief cells in the stomach and that degrades food proteins into peptides. Pepsin was discovered in 1836 by Theodor Schwann who also coined this enzyme's name from the Greek word pepsis, meaning digestion (peptein: to digest). It was the first animal enzyme to be discovered, and, in 1929, it became one of the first enzymes to be crystallized, by John H. Northrop. Pepsin is a digestive protease.
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