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Category:herbicides / pesticides
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 44.60 °C. @ 760.00 mm Hg
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| Boiling Point: | 156.00 °C. @ 760.00 mm Hg (est)
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| Vapor Pressure: | 6.000000 mmHg @ 20.00 °C. (est) |
| logP (o/w): | 6.500 |
| Soluble in: |
| | water, 0.02 mg/L @ 20 °C (exp) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| |
| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-duck LD50 4190 mg/kg
Pesticide Manual. Vol. 9, Pg. 791, 1991.
oral-mouse LD50 45 mg/kg
Pesticide Manual. Vol. 9, Pg. 791, 1991.
oral-rat LD50 22 mg/kg
Pesticide Manual. Vol. 9, Pg. 791, 1991.
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| Dermal Toxicity: |
skin-rat LD50 148 mg/kg
Pesticide Manual. Vol. 9, Pg. 791, 1991.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | herbicides / pesticides |
| Recommendation for tefluthrin usage levels up to: | | | not for fragrance use.
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| Recommendation for tefluthrin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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Retrospective analysis of the immunotoxic effects of plant protection products as reported in the Draft Assessment Reports for their peer review at EU level
View page or View pdf
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Reasoned opinion on the setting of maximum residue levels for tefluthrin in various crops
View page or View pdf
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Modification of the existing maximum residue level for tefluthrin in carrots
View page or View pdf
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Review of the existing maximum residue levels for tefluthrin according to Article 12 of Regulation (EC) No 396/2005
View page or View pdf
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| EPI System: View |
| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :11534837 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:3 |
| (2,3,5,6-tetrafluoro-4-methylphenyl)methyl (1S,3S)-3-[(Z)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate |
| Chemidplus:0079538322 |
| RTECS:GZ1227850 for cas# 79538-32-2 |
References:
| | (2,3,5,6-tetrafluoro-4-methylphenyl)methyl (1S,3S)-3-[(Z)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 11534837 |
| Pubchem (sid): | 135013165 |
Other Information:
| (IUPAC): | Atomic Weights of the Elements 2011 (pdf) |
| Videos: | The Periodic Table of Videos |
| tgsc: | Atomic Weights use for this web site |
| (IUPAC): | Periodic Table of the Elements |
| CHEBI: | View |
| HMDB (The Human Metabolome Database): | Search |
| ChemSpider: | View |
| Wikipedia: | View |
Formulations/Preparations:
•emulsifiable concentrate, and granules.
•force 3g insecticide (syngenta crop protection) tefluthrin 3%
•force cs insecticide (syngenta crop protection) tefluthrin 23.4%,
•force st insecticide (syngenta crop protection) tefluthrin 26.8%
•tefluthrin technical (syngenta crop protection) tefluthrin 94%
•tradenames: 'force' (amvac, syngenta); mixtures: 'imprimo' (+ imidacloprid) (bayer cropscience); 'traffic' (+ imidacloprid) (bayer cropscience). other tradenames: 'evict' (syngenta); 'forca' (syngenta); 'forza' (syngenta); 'attack' (sopra); mixtures: 'austral plus' (+ anthraquinone+ fludioxonil) (syngenta); 'montur' (+ imidacloprid) (bayer). discontinued names mixtures: 'austral' * (+ anthraquinone+ oxine-copper) (seed treatment) (la quinoline); 'elyxor star' * (+ anthraquinone+ fludioxonil) (novartis).
•tech. material is about 92% pure.
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Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | cyclopropanecarboxylic acid, 3-((1Z)-2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl-, (2,3,5,6-tetrafluoro-4-methylphenyl)methyl ester, (1R,3R)-rel- | | | cyclopropanecarboxylic acid, 3-(2-chloro-3,3,3-trifluoro-1-propenyl)-2,2-dimethyl-, (2,3,5,6-tetrafluoro-4-methylphenyl)methyl ester, (1-alpha,3-alpha(Z))-(+-)- | | | forza | | | tefluthrine | | 2,3,5,6- | tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate | | (2,3,5,6- | tetrafluoro-4-methylphenyl)methyl (1S,3S)-3-[(Z)-2-chloro-3,3,3-trifluoroprop-1-enyl]-2,2-dimethylcyclopropane-1-carboxylate |
Articles:
| PubMed:A site-specific ecological risk assessment for corn-associated insecticides. |
| PubMed:A multi-year field study to evaluate the environmental fate and agronomic effects of insecticide mixtures. |
| PubMed:Modeling of action potential generation in NG108-15 cells. |
| PubMed:Soil application of an encapsulated CO2 source and its potential for management of western corn rootworm larvae. |
| PubMed:The role of carbon dioxide as an orientation cue for western corn rootworm larvae within the maize root system: implications for an attract-and-kill approach. |
| PubMed:Use of solid phase microextraction to estimate toxicity: relating fiber concentrations to toxicity--part I. |
| PubMed:Parameters for pyrethroid insecticide QSAR and PBPK/PD models for human risk assessment. |
| PubMed:Coexpression with Auxiliary β Subunits Modulates the Action of Tefluthrin on Rat Na(v)1.6 and Na(v)1.3 Sodium Channels. |
| PubMed:Electrophysiological characterization of sodium-activated potassium channels in NG108-15 and NSC-34 motor neuron-like cells. |
| PubMed:Differential state-dependent modification of inactivation-deficient Nav1.6 sodium channels by the pyrethroid insecticides S-bioallethrin, tefluthrin and deltamethrin. |
| PubMed:Characterizing the effects of Eugenol on neuronal ionic currents and hyperexcitability. |
| PubMed:Differential state-dependent modification of rat Na(v)1.6 sodium channels expressed in human embryonic kidney (HEK293) cells by the pyrethroid insecticides tefluthrin and deltamethrin. |
| PubMed:Actions of Tefluthrin on Rat Na(v)1.7 Voltage-Gated Sodium Channels Expressed in Xenopus Oocytes. |
| PubMed:Multipesticide residue analysis in maize combining acetonitrile-based extraction with dispersive liquid-liquid microextraction followed by gas chromatography-mass spectrometry. |
| PubMed:Toxicity of pesticide and fertilizer mixtures simulating corn production to eggs of snapping turtles (Chelydra serpentina). |
| PubMed:Additivity of pyrethroid actions on sodium influx in cerebrocortical neurons in primary culture. |
| PubMed:Decomposition rates and residue-colonizing microbial communities of Bacillus thuringiensis insecticidal protein Cry3Bb-expressing (Bt) and non-Bt corn hybrids in the field. |
| PubMed:Mechanisms of pyrethroid insecticide-induced stimulation of calcium influx in neocortical neurons. |
| PubMed:Divergent actions of the pyrethroid insecticides S-bioallethrin, tefluthrin, and deltamethrin on rat Na(v)1.6 sodium channels. |
| PubMed:Wireworm management I: stand protection versus wireworm mortality with wheat seed treatments. |
| PubMed:Human embryonic kidney (HEK293) cells express endogenous voltage-gated sodium currents and Na v 1.7 sodium channels. |
| PubMed:Development of a rapid determination of pesticides in coated seeds using a high-performance liquid chromatography-UV detection system. |
| PubMed:Evidence for a separate mechanism of toxicity for the Type I and the Type II pyrethroid insecticides. |
| PubMed:Comparative functional observational battery study of twelve commercial pyrethroid insecticides in male rats following acute oral exposure. |
| PubMed:The mechanism of the actions of oxaliplatin on ion currents and action potentials in differentiated NG108-15 neuronal cells. |
| PubMed:Underlying mechanism of actions of tefluthrin, a pyrethroid insecticide, on voltage-gated ion currents and on action currents in pituitary tumor (GH3) cells and GnRH-secreting (GT1-7) neurons. |
| PubMed:Human and rat Nav1.3 voltage-gated sodium channels differ in inactivation properties and sensitivity to the pyrethroid insecticide tefluthrin. |
| PubMed:Actions of ATX-II and other gating-modifiers on Na(+) currents in HEK-293 cells expressing WT and DeltaKPQ hNa(V) 1.5 Na(+) channels. |
| PubMed:Modeling of action potential generation in NG108-15 cells. |
| PubMed:Mortality of a wireworm, Agriotes obscurus (Coleoptera: Elateridae), after topical application of various insecticides. |
| PubMed:Repellency of a wireworm, Agriotes obscurus (Coleoptera: Elateridae), on exposure to synthetic insecticides in a soil-less bioassay. |
| PubMed:Soil bioassay for studying behavioral responses of wireworms (Coleoptera: Elateridae) to insecticide-treated wheat seed. |
| PubMed:Effects of insecticide exposure on movement and population size estimates of predatory ground beetles (Coleoptera: Carabidae). |
| PubMed:Efficacy of various pyrethroid structures against a highly metabolically resistant isogenic strain of Helicoverpa armigera (Lepidoptera: Noctuidae) from China. |
| PubMed:Differential pharmacology of the cardiac anionic background current I(AB). |
| PubMed:An outwardly rectifying anionic background current in atrial myocytes from the human heart. |
| PubMed:Interactions of alternate hosts, postemergence grass control, and rootworm-resistant transgenic corn on western corn rootworm (Coleoptera: Chrysomelidae) damage and adult emergence. |
| PubMed:Abundance of Coleomegilla maculata (Coleoptera: Coccinellidae) in corn rootworm-resistant Cry3Bb1 maize. |
| PubMed:Toxin detection based on action potential shape analysis using a realistic mathematical model of differentiated NG108-15 cells. |
| PubMed:Relative potencies for acute effects of pyrethroids on motor function in rats. |
| PubMed:Microelectrode array recordings of cardiac action potentials as a high throughput method to evaluate pesticide toxicity. |
| PubMed:Structure-activity relationships for the action of 11 pyrethroid insecticides on rat Na v 1.8 sodium channels expressed in Xenopus oocytes. |
| PubMed:Mechanisms underlying the effects of the pyrethroid tefluthrin on action potential duration in isolated rat ventricular myocytes. |
| PubMed:Effect of Cry3Bb transgenic corn and tefluthrin on the soil microbial community: biomass, activity, and diversity. |
| PubMed:Differential effects of extracellular cesium on early afterdepolarizations in ventricular myocytes and arrhythmogenesis in isolated hearts of rats and guinea pigs. |
| PubMed:Differential effects of pyrethroids on volume-sensitive anion and organic osmolyte pathways. |
| PubMed:Larval susceptibility of an insecticide-resistant western corn rootworm (Coleoptera: Chrysomelidae) population to soil insecticides: laboratory bioassays, assays of detoxification enzymes, and field performance. |
| PubMed:Structure-activity and interaction effects of 14 different pyrethroids on voltage-gated chloride ion channels. |
| PubMed:Emergence of adult northern and western corn rootworms (Coleoptera: Chrysomelidae) following reduced soil insecticide applications. |
| PubMed:Determination of pyrethroid pesticide residues in processed fruits and vegetables by gas chromatography with electron capture and mass spectrometric detection. |
| PubMed:Cleanup of gloves contaminated with granular terbufos and tefluthrin. |
| PubMed:Tefluthrin modulates a novel anionic background conductance (I(AB)) in guinea-pig ventricular myocytes. |
| PubMed:Management of early-instar Japanese beetle (Coleoptera: Searabaeidae) in field-grown nursery crops. |
| PubMed:Effects of exposure time, material type, and granular pesticide on glove contamination. |
| PubMed:Actions of pyrethroid insecticides on sodium currents, action potentials, and contractile rhythm in isolated mammalian ventricular myocytes and perfused hearts. |
| PubMed:Interaction of insecticides, entomopathogenic nematodes, and larvae of the western corn rootworm (Coleoptera: Chrysomelidae). |
| PubMed:Selective extraction of pyrethroid pesticide residues from milk by solid-matrix dispersion. |
| PubMed:Clean-up of aqueous acetone vegetable extracts by solid-matrix partition for pyrethroid residue determination by gas chromatography-electron-capture detection. |
| PubMed:Factors Influencing Pyrethroid Resistance in a Permethrin-Selected Strain of the Soybean Looper, Pseudoplusia includens (Walker) |
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3D/inchi