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Category:indirect food additives: polymers
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water, 37.57 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-mouse LD50 1950 mg/kg
Takeda Kenkyusho Ho. Journal of the Takeda Research Laboratories. Vol. 39, Pg. 202, 1980.
oral-rat LD50 4130 mg/kg
American Industrial Hygiene Association Journal. Vol. 43, Pg. 89, 1982.
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| Dermal Toxicity: |
skin-rabbit LD50 > 10 mL/kg
Union Carbide Data Sheet. Vol. 1/11/1967
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| Inhalation Toxicity: |
inhalation-guinea pig LC50 12700 ppb/4H
BEHAVIORAL: EXCITEMENT
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
American Industrial Hygiene Association Journal. Vol. 23, Pg. 447, 1962.
inhalation-mouse LC50 9700 ppb/4H
BEHAVIORAL: EXCITEMENT
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
American Industrial Hygiene Association Journal. Vol. 23, Pg. 447, 1962.
inhalation-rabbit LC50 11 ppm/4H
GASTROINTESTINAL: CHANGES IN STRUCTURE OR FUNCTION OF SALIVARY GLANDS
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
BEHAVIORAL: EXCITEMENT
American Industrial Hygiene Association Journal. Vol. 23, Pg. 447, 1962.
inhalation-rat LCLo 600 ppm/6H
Union Carbide Data Sheet. Vol. 1/11/1967
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Safety in Use Information:
| Category: | | indirect food additives: polymers |
| Recommendation for meta-tolylidene diisocyanate usage levels up to: | | | not for fragrance use.
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| Recommendation for meta-tolylidene diisocyanate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | benzene, 1,3-diisocyanatomethyl- | | 2,4- | diisocyanato-1-methylbenzene | | 1,3- | diisocyanatomethylbenzene | | | toluene diisocyanate | | | toluene-2,4-diisocyanate (mixt. with toluene-2,6-diisocyanate) |
Articles:
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3D/inchi