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Category:pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 203.00 to 204.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 119.00 to 120.00 °C. @ 50.00 mm Hg
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| Vapor Pressure: | 0.303000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 186.00 °F. TCC ( 85.60 °C. ) (est)
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| logP (o/w): | 1.400 |
| Soluble in: |
| | water, 7085 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-bird - wild LD50 242 mg/kg
Archives of Environmental Contamination and Toxicology. Vol. 12, Pg. 355, 1983.
oral-cat LD50 > 50 mg/kg
National Technical Information Service. Vol. OTS0573041
intraperitoneal-mouse LD50 116 mg/kg
Archivio Italiano di Scienze Farmacologiche. Vol. 1, Pg. 284, 1951.
oral-mouse LD50 740 mg/kg
Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 25(8), Pg. 50, 1981.
oral-rabbit LD50 750 mg/kg
Vsesoyuznyi Institut Nauchnoi i Tekhnicheskoi Informatsii Vol. #4035-77
oral-rat LD50 450 mg/kg
Journal of Pharmacology and Experimental Therapeutics. Vol. 90, Pg. 260, 1947.
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| Dermal Toxicity: |
skin-rabbit LD50 3250 mg/kg
National Technical Information Service. Vol. OTS0573041
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | pharmaceuticals / chemical synthisis |
| Recommendation for meta-toluidine usage levels up to: | | | not for fragrance use.
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| Recommendation for meta-toluidine flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 3- | amino-1-methylbenzene | | 3- | aminotoluene | | m- | aminotoluene | | | benzenamine, 3-methyl- | | 3- | methylalanine | | 3- | methylaniline | | 3- | methylbenzenamine | | 3- | methylphenylamine | | 3- | toluidine | | m- | toluidine | | m- | tolylamine |
Articles:
| PubMed:Quantification of Nitrogen compounds in diesel fuel samples by comprehensive two-dimensional gas chromatography coupled with quadrupole mass spectrometry. |
| PubMed:Exposure of hairdressers to ortho- and meta-toluidine in hair dyes. |
| PubMed:Microscopically based calculations of the free energy barrier and dynamic length scale in supercooled liquids: the comparative role of configurational entropy and elasticity. |
| PubMed:Optical storage in azobenzene-containing epoxy polymers processed as Langmuir Blodgett films. |
| PubMed:Density and confinement effects of glass forming m-toluidine in nanoporous Vycor investigated by depolarized dynamic light scattering. |
| PubMed:Factors affecting the selectivity of the photocatalytic conversion of nitroaromatic compounds over TiO2 to valuable nitrogen-containing organic compounds. |
| PubMed:Laser therapy as an effective method for implant surface decontamination: a histomorphometric study in rats. |
| PubMed:Evaluation of the Dyre shoving model using dynamic data near the glass temperature. |
| PubMed:Comparative studies of the dynamics in viscous liquids by means of dielectric spectroscopy and field cycling NMR. |
| PubMed:Adsorption and separation of reactive aromatic isomers and generation and stabilization of their radicals within cadmium(II)-triazole metal-organic confined space in a single-crystal-to-single-crystal fashion. |
| PubMed:Synthesis, characterization and cytotoxicity of iodo-bridged binuclear platinum(II) complexes. |
| PubMed:High resolution electronic spectroscopy of o- and m-toluidine in the gas phase. barrier height determinations for the methyl group torsional motions. |
| PubMed:A direct test of the correlation between elastic parameters and fragility of ten glass formers and their relationship to elastic models of the glass transition. |
| PubMed:Comparison of methods for identifying ano-genital injury after consensual intercourse. |
| PubMed:Tuning the supramolecular chirality of polyaniline by methyl substitution. |
| PubMed:The measurement of mechanical properties of glycerol, m-toluidine, and sucrose benzoate under consideration of corrected rheometer compliance: an in-depth study and review. |
| PubMed:Monoarylamines in the general population--a cross-sectional population-based study including 1004 Bavarian subjects. |
| PubMed:Analysis of a heterodyne-detected transient-grating experiment on a molecular supercooled liquid. II. Application to m-toluidine. |
| PubMed:Structure-property relationships of DEAEM-containing bone cements: effect of the substitution of a methylene group by an aromatic ring. |
| PubMed:On the correlation between fragility and stretching in glass-forming liquids. |
| PubMed:2-[(1S,3S)-3-Acetyl-2,2-dimethyl-cyclo-butyl]-N-(m-tol-yl)acetamide. |
| PubMed:Dynamic shear modulus of glycerol: corrections due to instrument compliance. |
| PubMed:Tuning the structure of SDS micelles by substituted anilinium ions. |
| PubMed:Shear stress relaxation and physical aging study on simple glass-forming materials. |
| PubMed:Effect of dietary fat on selected parameters of toxicity following 1- or 3-month exposure of rats to toluidine isomers. |
| PubMed:Ergodic to nonergodic transition in liquids with a local order: the case of m-toluidine. |
| PubMed:Slow dynamics of supercooled m-toluidine investigated by mechanical spectroscopy. |
| PubMed:Dynamics of glassy and liquid m-toluidine investigated by high-resolution dielectric spectroscopy. |
| PubMed:Two biologically active thiophene-3-carboxamide derivatives. |
| PubMed:Study of charge transfer complexes of menadione (vitamin K3) with a series of anilines. |
| PubMed:New one-dimensional azido-bridged manganese(II) coordination polymers exhibiting alternating ferromagnetic-antiferromagnetic interactions: structural and magnetic studies. |
| PubMed:Analysis of some aromatic amines by means of derivative spectrophotometry. |
| PubMed:Solid-phase microextraction of monocyclic aromatic amines using novel fibers coated with crown ether. |
| PubMed:Liquid chromatographic/mass spectrometric determination of desmedipham and phenmedipham and their metabolites in soil. |
| PubMed:Haemoglobin adducts from aromatic amines in children in relation to area of residence and exposure to environmental tobacco smoke. |
| PubMed:Structures of mutagens produced by the co-mutagen norharman with o- and m-toluidine isomers. |
| PubMed:Biological monitoring of phenmedipham: determination of m-toluidine in urine. |
| PubMed:Determination of the levels of aromatic amines in indoor and outdoor air in Italy. |
| PubMed:Assay of tolnaftate and related impurities by isocratic supercritical fluid chromatography. |
| PubMed:Enzymatic method for assaying uric acid in serum with a new tetrazolium salt produces water-soluble formazan dye. |
| PubMed:Formation of DNA adducts by the co-mutagen norharman with aromatic amines. |
| PubMed:Biomonitoring of urinary aromatic amines and arylamine hemoglobin adducts in exposed workers and nonexposed control persons. |
| PubMed:Magnetic state of poly(m-toluidine): Dependence on absorbed water. |
| PubMed:Serum sialic acid enzymatic assay based on microtitre plates: application for measuring capillary serum sialic acid concentrations. |
| PubMed:Primary aromatic amines from side-stream cigarette smoke are common contaminants of indoor air. |
| PubMed:Liquid film pertraction-A liquid membrane preconcentration technique. |
| PubMed:Automated microanalysis of creatinine by coupled enzyme reactions. |
| PubMed:Adsorptive stripping voltammetry determination of molybdenum(VI) in water and soil. |
| PubMed:Enzymatic assay of 3-mercaptopyruvate sulfurtransferase activity in human red blood cells using pyruvate oxidase. |
| PubMed:Rapid enzymatic analysis of plasma for tyrosine. |
| PubMed:[Gas chromatography methods of the measurement of concentrations of 2-bromo-6-chloro-4-nitroaniline, N,N-dioxyethyl-M-chloroaniline, N-oxyethyl-N-beta-cyanoethylaniline and N-ethyl-N-beta-cyanoethyl-M-toluidine in the working zone air]. |
| PubMed:[Plasmids for biphenyl, chlorobiphenyl and metatoluylate degradation from Pseudomonas putida]. |
| PubMed:Photodynamic inactivation of rubella virus enhances recombination with a latent virus of a baby hamster kidney cell line BHK21. |
| PubMed:Test-strip method for measuring lactate in whole blood. |
| PubMed:Histochemical demonstration of neurotoxic esterase. |
| PubMed:Anticalcification treatments of bioprosthetic heart valves: in vivo studies in sheep. |
| PubMed:A colorimetric assay for the measurement of D-glucose consumption by cultured cells. |
| PubMed:The effects of anticalcification treatments on bioprosthetic heart valves implanted in sheep. |
| PubMed:A rapid assay method for ammonia using glutamine synthetase from glutamate-producing bacteria. |
| PubMed:Kinetic assay of gamma-glutamyltransferase with use of bilirubin oxidase as a coupled enzyme. |
| PubMed:Effect of toluidines on drug metabolizing enzymes in rat liver, kidney and lung. |
| PubMed:[The synthesis, analysis, stability and biotransformation of N-(3-methylphenyl)-N'-cyanobenzamidine and analogues (author's transl)]. |
| PubMed:Metabolism of ortho-, meta-, and para-toluidine in the adult male rat. |
| PubMed:Testing of twenty-one environmental aromatic amines or derivatives for long-term toxicity or carcinogenicity. |
| PubMed:Determination of aminocresol isomers by high-speed liquid chromatography. |
| PubMed:Percutaneous penetration and metabolism of topical (14C)flutamide in men. |
| PubMed:Disposition of a new, nonsteroid, antiandrogen, alpha,alpha,alpha-trifluoro-2-methyl-4'-nitro-m-propionotoluidide (Flutamide), in men following a single oral 200 mg dose. |
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3D/inchi