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sodium fumarate
2-butenedioic acid, sodium salt, (2E)- (1:2)

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Name:sodium (E)-but-2-enedioate
CAS Number: 7704-73-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:231-725-2
FDA UNII:F11949924I
Molecular Weight:139.06244928
Formula:C4 H4 Na O4
NMR Predictor:Predict (works with chrome or firefox)
Category:flavor enhancers, buffering agents, acidulants
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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JECFA Food Additive: Sodium Fumarate
GSFA Codex: Sodium fumarates (365)
FDA Mainterm (SATF):7704-73-6 ; SODIUM FUMARATE
FDA Regulation:
FDA PART 172 -- FOOD ADDITIVES PERMITTED FOR DIRECT ADDITION TO FOOD FOR HUMAN CONSUMPTION
Subpart D--Special Dietary and Nutritional Additives
Sec. 172.350 Fumaric acid and salts of fumaric acid.
 
Physical Properties:
Appearance:white crystalline powder (est)
Assay: 98.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 355.00 to 356.00 °C. @ 760.00 mm Hg (est)
Vapor Pressure:0.000005 mmHg @ 25.00 °C. (est)
Flash Point: 361.00 °F. TCC ( 183.00 °C. ) (est)
logP (o/w): -0.008 (est)
Soluble in:
 water
 
Organoleptic Properties:
Odor Description:at 100.00 %. odorless
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: buffering agents
 
Suppliers:
BOC Sciences
For experimental / research use only.
Sodium Fumarate 95%
Qingdao Dacon Trading
MonoSodium Fumarate
 
Safety Information:
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
flavor enhancers, buffering agents, acidulants
Recommendation for sodium fumarate usage levels up to:
 not for fragrance use.
 
 
Safety References:
European Food Safety Authority (EFSA) reference(s):

Review of substances/agents that have direct beneficial effect on the environment: mode of action and assessment of efficacy
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EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :10197734
National Institute of Allergy and Infectious Diseases:Data
sodium (E)-but-2-enedioate
Chemidplus:0007704736
 
References:
 sodium (E)-but-2-enedioate
NIST Chemistry WebBook:Search Inchi
Pubchem (cid):10197734
Pubchem (sid):134992315
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
FooDB:FDB017286
FDA Listing of Food Additive Status:View
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
2-butenedioic acid (E)-, sodium salt
(E)-2-butenedioic acid sodium salt
2-butenedioic acid, sodium salt, (2E)- (1:2)
 fumaric acid sodium salt
 fumaric acid, sodium salt
 sodium (2E)-but-2-enedioate
 sodium (E)-but-2-enedioate
 sodium 2-butenedioate, (E)-
 

Articles:

PubMed:Nanofiltration, bipolar electrodialysis and reactive extraction hybrid system for separation of fumaric acid from fermentation broth.
PubMed:Development of nalidixic acid amphotericin B vancomycin (NAV) medium for the isolation of Campylobacter ureolyticus from the stools of patients presenting with acute gastroenteritis.
PubMed:[Effect of citric acid on synthesis of surfactants in Rhodococcus erythropolis IMV Ac-5017].
PubMed:Propionate precursors and other metabolic intermediates as possible alternative electron acceptors to methanogenesis in ruminal fermentation in vitro.
PubMed:Comparison of fumaric acid production by Rhizopus oryzae using different neutralizing agents.
PubMed:Influence of sodium fumarate addition on rumen fermentation in vitro.
PubMed:Expression and secretion of functional miniantibodies McPC603scFvDhlx in cell-wall-less L-form strains of Proteus mirabilis and Escherichia coli: a comparison of the synthesis capacities of L-form strains with an E. coli producer strain.
PubMed:Production of R-(-)-Ketoprofen from an Amide Compound by Comamonas acidovorans KPO-2771-4.
PubMed:The effect of electron transport (ET) inhibitors and thiabendazole on the fumarate reductase (FR) and succinate dehydrogenase (SDH) of Strongyloides ratti infective (L3) larvae.
PubMed:Strongyloides ratti: fumarate reductase and succinate dehydrogenase activities of infective larvae.
PubMed:[Activation of the processes of lipid peroxidation in the small-intestinal mucosa and liver in peritonitis and possible ways of their correction by a complex infusion-detoxification therapy].
PubMed:Selective medium for isolation of Bacteroides gracilis.
PubMed:[The use of the new Soviet crystalloid mafusol as a hemodiluent in surgery using artificial circulation].
PubMed:[Effect of sodium fumarate on the effectiveness of infusion therapy in experimental blood loss].
PubMed:A Mechanism of Chlorosis Caused by 1,3-Dimethyl-4-(2,4-dichlorobenzoyl)-5-hydroxypyrazole, a Herbicidal Compound.
PubMed:Agar medium for use in susceptibility testing of bacteria from human periodontal pockets.
PubMed:Effect of medium composition on the growth and asparaginase production of Vibrio succinogenes.
PubMed:Cell yields of Escherichia coli during anaerobic growth on fumarate and molecular hydrogen.
PubMed:Improved growth media for Vibrio succinogenes.
PubMed:L-Asparaginase from Proteus vulgaris.
PubMed:Development of competence of Haemophilus influenzae.
PubMed:Enzymatic production of L-alanine by Pseudomonas dacunhae.
 
Notes:
Nutrient supplement Sodium fumarate, also called disodium fumarate, is a compound with the molecular formula Na2C4H2O4. It is the sodium salt of fumaric acid, used as an acidity regulator in processed foods. Sodium fumarate and fumaric acid are sometimes used as terminal electron acceptors in the cultivation of certain anaerobic microorganisms. It appears as an odourless, white, crystalline powder and is soluble in water.
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