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Category:information only not used for fragrances or flavors
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Melting Point: | 100.50 °C. @ 760.00 mm Hg
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| Boiling Point: | 311.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 0.001000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 280.00 °F. TCC ( 137.50 °C. ) (est)
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| logP (o/w): | 4.230 |
| Soluble in: |
| | water, 1.018 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
subcutaneous-mouse LD50 690 mg/kg Arzneimittel-Forschung. Drug Research. Vol. 8, Pg. 107, 1958.
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | information only not used for fragrances or flavors |
| Recommendation for xanthene usage levels up to: | | | not for fragrance use.
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| Recommendation for xanthene flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 10H-9-oxa | anthracene | | | dibenzo[a,e]pyran | | 9H- | xanthene |
Articles:
| PubMed:Multi-dye residue analysis of triarylmethane, xanthene, phenothiazine and phenoxazine dyes in fish tissues by ultra-performance liquid chromatography-tandem mass spectrometry. |
| PubMed:The promiscuous protein binding ability of erythrosine B studied by metachromasy (metachromasia). |
| PubMed:Low-calorie bread baked with charred cellulose granules and wheat flour to eliminate toxic xanthene food dye in the alimentary canal. |
| PubMed:New fluorescent pH sensors based on covalently linkable PET rhodamines. |
| PubMed:Genotoxic and mutagenic effects of erythrosine B, a xanthene food dye, on HepG2 cells. |
| PubMed:Adsorption mechanism for xanthene dyes to cellulose granules. |
| PubMed:Xanthene food dye, as a modulator of Alzheimer's disease amyloid-beta peptide aggregation and the associated impaired neuronal cell function. |
| PubMed:Hydrogen [corrected] peroxide-dependent photocytotoxicity by phloxine B, a xanthene-type food colorant. |
| PubMed:Development of a fluorescence polarization immunoassay for the detection of melamine in milk and milk powder. |
| PubMed:The food colorant erythrosine is a promiscuous protein-protein interaction inhibitor. |
| PubMed:Toxicity of xanthene food dyes by inhibition of human drug-metabolizing enzymes in a noncompetitive manner. |
| PubMed:Light emitting diode induced chemiluminescence and its application as a detector for high performance liquid chromatography. |
| PubMed:Enhanced inactivation of foodborne pathogenic and spoilage bacteria by FD&C Red no. 3 and other xanthene derivatives during ultrahigh pressure processing. |
| PubMed:Inhibition of human CYP3A4, UGT1A6, and P-glycoprotein with halogenated xanthene food dyes and prevention by superoxide dismutase. |
| PubMed:Polybrominated hexahydroxanthene derivatives (PBHDs) and other halogenated natural products from the Mediterranean sponge Scalarispongia scalaris in marine biota. |
| PubMed:The role of copper(II) in the bridging reactions of (+)-catechin by glyoxylic acid in a model white wine. |
| PubMed:New polyphenolic compounds with xanthylium skeletons formed through reaction between (+)-catechin and glyoxylic acid. |
| PubMed:Stimulating effect of xanthene dyes on immunoglobulin produced in vitro by rat spleen lymphocytes. |
| PubMed:Effect of organic synthetic food colours on mitochondrial respiration. |
| PubMed:Comparison of in vitro actions with behavioral effects of antimuscarinic agents. |
| PubMed:Final report of the Color Additive Scientific Review Panel. |
| PubMed:A review of the genotoxicity of food, drug and cosmetic colours and other azo, triphenylmethane and xanthene dyes. |
| PubMed:Biochemical decomposition of coal-tar dyes. II. Acute toxicity of coal-tar dyes and their decomposed products. |
| PubMed:Mutagenicity testing of certified food colors and related azo, xanthene and triphenylmethane dyes with the Salmonella/microsome system. |
| PubMed:[Food additives and their mutagenic effect. VII. Testing of several xanthene dyes for their mutagenic effect on Escherichi coli]. |
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