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Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Boiling Point: | 749.30 °C. @ 760.00 mm Hg (est)
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| Flash Point: | 764.00 °F. TCC ( 406.90 °C. ) (est)
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| logP (o/w): | 0.680 (est) |
| Soluble in: |
| | water, 1484 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for rhapontin usage levels up to: | | | not for fragrance use.
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| Recommendation for rhapontin flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
| | (2S,3R,4S,5S,6R)-2-[3-hydroxy-5-[(E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 637213 |
| Pubchem (sid): | 135033004 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| beta-d- | glucopyranoside, 3-hydroxy-5-(2-(3-hydroxy-4-methoxyphenyl)ethenyl)phenyl (9CI) | | | glucopyranoside, rhapontigenin-3, beta-D- | | 3- | hydroxy-5-(2-(3-hydroxy-4-methoxyphenyl)ethenyl)phenyl-beta-d-glucopyranoside | | 3- | hydroxy-5-(2-(3-hydroxy-4-methoxyphenyl)vinyl)phenyl-beta-D-glucopyranoside | | (2S,3R,4S,5S,6R)-2-[3- | hydroxy-5-[(E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]phenoxy]-6-(hydroxymethyl)oxane-3,4,5-triol | | | ponticin | | | rhaponticin | | | rhaponticine | | | rhapontigenin, 3-beta-D-glucopyranoside |
Articles:
| PubMed:Antihyperlipidemic effects of rhapontin and rhapontigenin from rheum undulatum in rats fed a high-cholesterol diet. |
| PubMed:[Study on preparation of deoxyrhaponti-beta-cyclodextrin super-molecular inclusion complex and performance of inclusion complex]. |
| PubMed:Inhibitory effect of desoxyrhaponticin and rhaponticin, two natural stilbene glycosides from the Tibetan nutritional food Rheum tanguticum Maxim. ex Balf., on fatty acid synthase and human breast cancer cells. |
| PubMed:Enhanced pharmacokinetics and anti-tumor efficacy of PEGylated liposomal rhaponticin and plasma protein binding ability of rhaponticin. |
| PubMed:Quantitative assessment of traditional Oriental herbal formulation Samhwangsasim-tang using UPLC technique. |
| PubMed:A simple and rapid spectrofluorimetric method for determining the pharmacokinetics and metabolism of rhaponticin in rat plasma, feces and urine using a cerium probe. |
| PubMed:Rhapontigenin converted from rhapontin purified from Rheum undulatum enhances the inhibition of melanin synthesis. |
| PubMed:Solvent effects on the absorption and fluorescence spectra of rhaponticin: experimental and theoretical studies. |
| PubMed:Synthesis and biological evaluation of a folate-targeted rhaponticin conjugate. |
| PubMed:Preparative isolation and purification of three stilbene glycosides from the tibetan medicinal plant Rheum tanguticum maxim. Ex Balf. by high-speed counter-current chromatography. |
| PubMed:Magnetic molecularly imprinted polymer for the detection of rhaponticin in Chinese patent medicines. |
| PubMed:The possible mechanism of rhapontigenin influencing antifungal activity on Candida albicans. |
| PubMed:One-step preparative separation of two polyhydroxystilbenes from Rheum likiangense Sam. by high-speed counter-current chromatography. |
| PubMed:Pharmacokinetics, bioavailability and metabolism of rhaponticin in rat plasma by UHPLC-Q-TOF/MS and UHPLC-DAD-MSn. |
| PubMed:Studies on the binding of rhaponticin with human serum albumin by molecular spectroscopy, modeling and equilibrium dialysis. |
| PubMed:[Binding mechanism of rhaponticin and human serum albumin]. |
| PubMed:Chemical-based species classification of rhubarb using simultaneous determination of five bioactive substances by HPLC and LDA analysis. |
| PubMed:Assessment for the light-induced cis-trans isomerization of rhapontigenin and its glucoside rhaponticin by capillary electrophoresis and spectrometric methods. |
| PubMed:Regulating volume transitions of highly responsive hydrogel scaffolds by adjusting the network properties of microgel building block colloids. |
| PubMed:Evaluation of the antibacterial activity of rhapontigenin produced from rhapontin by biotransformation against Propionibacterium acnes. |
| PubMed:Rhaponticin from rhubarb rhizomes alleviates liver steatosis and improves blood glucose and lipid profiles in KK/Ay diabetic mice. |
| PubMed:Coumarin, anthroquinone and stilbene derivatives with anticholinesterase activity. |
| PubMed:Polymer-associated liposomes as a novel delivery system for cyclodextrin-bound drugs. |
| PubMed:Antioxidant actions of phenolic compounds found in dietary plants on low-density lipoprotein and erythrocytes in vitro. |
| PubMed:Induction of apoptosis by rhapontin having stilbene moiety, a component of rhubarb (Rheum officinale Baillon) in human stomach cancer KATO III cells. |
| PubMed:Protective effect of rhubarb derivatives on amyloid beta (1-42) peptide-induced apoptosis in IMR-32 cells: a case of nutrigenomic. |
| PubMed:Desoxyrhaponticin (3,5-dihydroxy-4'-methoxystilbene 3-O-beta-D-glucoside) inhibits glucose uptake in the intestine and kidney: In vitro and in vivo studies. |
| PubMed:Insulin sensitizing and alpha-glucoamylase inhibitory action of sennosides, rheins and rhaponticin in Rhei Rhizoma. |
| PubMed:[Determination of six effective components in Rheum by cyclodextrin modified micellar electrokinetic chromatography]. |
| PubMed:[A new ecdysone hormone rhaponticum from Rhaponticum uniflorum (L.) DC]. |
| PubMed:Antithrombotic and antiallergic activities of rhaponticin from Rhei Rhizoma are activated by human intestinal bacteria. |
| PubMed:Stable isotope labeling pattern of resveratrol and related natural stilbenes. |
| PubMed:Downregulation of the cyclin D1/Cdk4 complex occurs during resveratrol-induced cell cycle arrest in colon cancer cell lines. |
| PubMed:Metabolism of rhaponticin and chrysophanol 8-o-beta-D-glucopyranoside from the rhizome of rheum undulatum by human intestinal bacteria and their anti-allergic actions. |
| PubMed:Inhibitory effects of hydroxystilbenes on cyclooxygenase from sheep seminal vesicles. |
| PubMed:[Quantitative determination of rhapontin in root of Rheum hotaoense by TLC-scanning]. |
| PubMed:[Determination of anthraquinone derivatives in rhubarb grown for export]. |
| PubMed:Ethnopharmacologic study of Chinese rhubarb. |
| PubMed:[Effects of rhapontin of rheum hotaoense on serum lipid and lipoprotein levels (serum)]. |
| PubMed:Substrate specificity in vivo and in vitro in the formation of stilbenes. Biosynthesis of rhaponticin. |
| PubMed:[A preliminary study of the correlation between phylogeny, chemical constituents and therapeutic effects of Rheum species]. |
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3D/inchi