| PubMed:Simultaneous determination of the content of isoquinoline alkaloids in Dicranostigma leptopodum (Maxim) Fedde and the effective fractionation of the alkaloids by high-performance liquid chromatography with diode array detection. |
| PubMed:Direct analysis of quaternary alkaloids by in situ reactive desorption corona beam ionization MS. |
| PubMed:Influence of vinegar and wine processing on the alkaloid content and composition of the traditional Chinese medicine Corydalis Rhizoma (Yanhusuo). |
| PubMed:Antidiabetic effects of the Cimicifuga racemosa extract Ze 450 in vitro and in vivo in ob/ob mice. |
| PubMed:Natural products as potential human ether-a-go-go-related gene channel inhibitors - screening of plant-derived alkaloids. |
| PubMed:Cytotoxicity of Aporphine, Protoberberine, and Protopine Alkaloids from Dicranostigma leptopodum (Maxim.) Fedde. |
| PubMed:Simultaneous determination of paeoniflorin, albiflorin, ferulic acid, tetrahydropalmatine, protopine, typhaneoside, senkyunolide I in Beagle dogs plasma by UPLC-MS/MS and its application to a pharmacokinetic study after Oral Administration of Shaofu Zhuyu Decoction. |
| PubMed:Comparisons of pharmacokinetic and tissue distribution profile of four major bioactive components after oral administration of Xiang-Fu-Si-Wu Decoction effective fraction in normal and dysmenorrheal symptom rats. |
| PubMed:[Network pharmacology study on major active compounds of siwu decoction analogous formulae for treating primary dysmenorrhea of gynecology blood stasis syndrome]. |
| PubMed:Improved sanguinarine production via biotic and abiotic elicitations and precursor feeding in cell suspensions of latex-less variety of Papaver somniferum with their gene expression studies and upscaling in bioreactor. |
| PubMed:Facile synthesis of tetrahydroprotoberberine and protoberberine alkaloids from protopines and study on their antibacterial activities. |
| PubMed:Identification and quantification of the main active anticancer alkaloids from the root of Glaucium flavum. |
| PubMed:A HPLC-MS/MS method for the simultaneous quantitation of six alkaloids of Rhizoma Corydalis Decumbentis in rat plasma and its application to a pharmacokinetic study. |
| PubMed:A new protoberberine alkaloid from Meconopsis simplicifolia (D. Don) Walpers with potent antimalarial activity against a multidrug resistant Plasmodium falciparum strain. |
| PubMed:[In vitro transdermal delivery of the active fraction of xiangfusiwu decoction based on principal component analysis]. |
| PubMed:Pharmaceutical applications of the benzylisoquinoline alkaloids from Argemone mexicana L. |
| PubMed:Identification of the absorbed constituents after oral administration of Yuanhu Zhitong prescription extract and its pharmacokinetic study by rapid resolution liquid chromatography/quadrupole time-of-flight. |
| PubMed:Dioxygenases catalyze O-demethylation and O,O-demethylenation with widespread roles in benzylisoquinoline alkaloid metabolism in opium poppy. |
| PubMed:Revealing the anti-tumoral effect of Algerian Glaucium flavum roots against human cancer cells. |
| PubMed:Comparative pharmacokinetics and bioavailability of four alkaloids in different formulations from Corydalis decumbens. |
| PubMed:Simultaneous quantification of 11 isoquinoline alkaloids in Corydalis impatiens (Pall.) Fisch by HPLC. |
| PubMed:A review on ethnobotany, phytochemistry and pharmacology of Fumaria indica (Fumitory). |
| PubMed:Capillary electrophoretic study of the synergistic biological effects of alkaloids from Chelidonium majus L. in normal and cancer cells. |
| PubMed:Integration of transcriptome, proteome and metabolism data reveals the alkaloids biosynthesis in Macleaya cordata and Macleaya microcarpa. |
| PubMed:Isolation and characterization of a cDNA encoding (S)-cis-N-methylstylopine 14-hydroxylase from opium poppy, a key enzyme in sanguinarine biosynthesis. |
| PubMed:A sensitive and selective liquid chromatography-tandem mass spectrometry method for simultaneous determination of five isoquinoline alkaloids from Chelidonium majus L. in rat plasma and its application to a pharmacokinetic study. |
| PubMed:Large-scale separation of alkaloids from Corydalis bungeana Turcz. by pH-zone-refining counter-current chromatography. |
| PubMed:Application of a liquid chromatography-tandem mass spectrometry method to the pharmacokinetics, tissue distribution and excretion studies of Dactylicapnos scandens in rats. |
| PubMed:Identification of pavinane alkaloids in the genera Argemone and Eschscholzia by GC-MS. |
| PubMed:Establishment of a search library about benzylisoquinoline alkaloids based on selective separation on the binaphthyl column and standard analysis on C18 column. |
| PubMed:[Study on absorption ingredients of yuanhuzhitong pill by everted intestinal sac method]. |
| PubMed:Genetic and chemical components analysis of Papaver setigerum naturalized in Korea. |
| PubMed:Phytochemical and biological activity studies of the Bhutanese medicinal plant Corydalis crispa. |
| PubMed:Antimalarial alkaloids from a Bhutanese traditional medicinal plant Corydalis dubia. |
| PubMed:[Chemical constituents from Corydalis yanhusuo]. |
| PubMed:Fluorescence spectral analysis for the discrimination of complex, similar mixtures with the aid of chemometrics. |
| PubMed:Design and evaluation of self-emulsifying drug delivery systems of Rhizoma corydalis decumbentis extracts. |
| PubMed:Molecular cloning and characterization of a cytochrome P450 in sanguinarine biosynthesis from Eschscholzia californica cells. |
| PubMed:Protopine reduces the inflammatory activity of lipopolysaccharide-stimulated murine macrophages. |
| PubMed:Effect of wine and vinegar processing of Rhizoma Corydalis on the tissue distribution of tetrahydropalmatine, protopine and dehydrocorydaline in rats. |
| PubMed:Alkaloids from Papaver coreanum. |
| PubMed:Induction of heme oxygenase-1 by Macleaya cordata extract and its constituent sanguinarine in RAW264.7 cells. |
| PubMed:[Determination of four alkaloids in Corydalis decumbens by HPLC]. |
| PubMed:Preparative isolation of alkaloids from Dactylicapnos scandens using pH-zone-refining counter-current chromatography by changing the length of the separation column. |
| PubMed:Protopine, a novel microtubule-stabilizing agent, causes mitotic arrest and apoptotic cell death in human hormone-refractory prostate cancer cell lines. |
| PubMed:Rapid discrimination and quantification of alkaloids in Corydalis Tuber by near-infrared spectroscopy. |
| PubMed:Alkaloids from Chelidonium majus and their inhibitory effects on LPS-induced NO production in RAW264.7 cells. |
| PubMed:CYP2C19 progress curve analysis and mechanism-based inactivation by three methylenedioxyphenyl compounds. |
| PubMed:In vitro metabolic interactions between black cohosh (Cimicifuga racemosa) and tamoxifen via inhibition of cytochromes P450 2D6 and 3A4. |
| PubMed:Identification of a novel bacterial K(+) channel. |
| PubMed:Simultaneous quantification of 17 constituents from Yuanhu Zhitong tablet using rapid resolution liquid chromatography coupled with a triple quadrupole electrospray tandem mass spectrometry. |
| PubMed:Capillary electrophoresis with LED-induced native fluorescence detection for determination of isoquinoline alkaloids and their cytotoxicity in extracts of Chelidonium majus L. |
| PubMed:Alkaloids and flavonoids of Argemone mexicana. |
| PubMed:[Simultaneous determination of four alkaloids in Corydalis decumbens (Thunb.) Pers. by high performance liquid chromatography-tandem mass spectrometry]. |
| PubMed:Chemical study and anti-inflammatory, analgesic and antioxidant activities of the leaves of Aristotelia chilensis (Mol.) Stuntz, Elaeocarpaceae. |
| PubMed:Seasonal variation of bioactive alkaloid contents in Macleaya microcarpa (Maxim.) Fedde. |
| PubMed:Protopine and allocryptopine increase mRNA levels of cytochromes P450 1A in human hepatocytes and HepG2 cells independently of AhR. |
| PubMed:Preparative isolation of alkaloids from Corydalis bungeana Turcz. by high-speed counter-current chromatography using stepwise elution. |
| PubMed:Acetylcholinesterase and butyrylcholinesterase inhibitory compounds from Chelidonium majus (Papaveraceae). |
| PubMed:[Determination of protopine in Corydalis racemose by HPLC]. |
| PubMed:Phytochemical and antimicrobial characterization of Macleaya cordata herb. |
| PubMed:Optimization of microwave-assisted extraction of protopine and allocryptopine from stems of Macleaya cordata (Willd) R. Br. using response surface methodology. |
| PubMed:A study on separation and extraction of four main alkaloids in Macleaya cordata (Willd) R. Br. with strip dispersion hybrid liquid membrane. |
| PubMed:In vivo anthelmintic activity of five alkaloids from Macleaya microcarpa (Maxim) Fedde against Dactylogyrus intermedius in Carassius auratus. |
| PubMed:Validated liquid chromatography-tandem mass spectrometry method for quantitative determination of dauricine in human plasma and its application to pharmacokinetic study. |
| PubMed:Acetylcholinesterase inhibitors from Corydalis yanhusuo. |
| PubMed:BIAdb: a curated database of benzylisoquinoline alkaloids. |
| PubMed:Simultaneous determination of seven main alkaloids of Chelidonium majus L. by ultra-performance LC with photodiode-array detection. |
| PubMed:Extractions of isoquinoline alkaloids with butanol and octanol. |
| PubMed:Screening of antinociceptive components in Corydalis yanhusuo W.T. Wang by comprehensive two-dimensional liquid chromatography/tandem mass spectrometry. |
| PubMed:Electron ionisation mass spectral study of 2-(2-carboxy-4, 5-dimethoxyphenyl)-6,7-dimethoxyisoquinolinium inner salt. |
| PubMed:Isoquinoline alkaloids from Macleaya cordata active against plant microbial pathogens. |
| PubMed:[Alkaloids from Dactylicapnos scandens Hutch]. |
| PubMed:[Alkaloids from Macleaya cordata]. |
| PubMed:Alkaloids from Mongolian species Hypecoum lactiflorum Kar. et Kir. Pazij. |
| PubMed:Antiplasmodial agents from the Bhutanese medicinal plant Corydalis calliantha. |
| PubMed:Simultaneous determination of tetrahydropalmatine, protopine, and palmatine in rat plasma by LC-ESI-MS and its application to a pharmacokinetic study. |
| PubMed:Analysis of alkaloids in Macleaya cordata (Willd.) R. Br. using high-performance liquid chromatography with diode array detection and electrospray ionization mass spectrometry. |
| PubMed:Protective effects of protopine on hydrogen peroxide-induced oxidative injury of PC12 cells via Ca(2+) antagonism and antioxidant mechanisms. |
| PubMed:Rapid TLC/GC-MS identification of acetylcholinesterase inhibitors in alkaloid extracts. |
| PubMed:Hepatoprotective potential of Fumaria indica Pugsley whole plant extracts, fractions and an isolated alkaloid protopine. |
| PubMed:On the synthesis of protopine alkaloids. |
| PubMed:Protective effect of protopine on the focal cerebral ischaemic injury in rats. |
| PubMed:Conventional sample enrichment strategies combined with high-performance liquid chromatography-solid phase extraction-nuclear magnetic resonance analysis allows analyte identification from a single minuscule Corydalis solida plant tuber. |
| PubMed:Antiviral and antimicrobial profiles of selected isoquinoline alkaloids from Fumaria and Corydalis species. |
| PubMed:Molecular cloning and characterization of tetrahydroprotoberberine cis-N-methyltransferase, an enzyme involved in alkaloid biosynthesis in opium poppy. |
| PubMed:New tetrahydroprotoberberine N-oxide alkaloids and cytotoxic constituents of Corydalis tashiroi. |
| PubMed:Rapid determination of protopine, allocryptopine, sanguinarine and chelerythrine in fruits of Macleaya cordata by microwave-assisted solvent extraction and HPLC-ESI/MS. |
| PubMed:Poppy alkaloid profiling by electrospray tandem mass spectrometry and electrospray FT-ICR mass spectrometry after [ring-13C6]-tyramine feeding. |
| PubMed:Gene transcript and metabolite profiling of elicitor-induced opium poppy cell cultures reveals the coordinate regulation of primary and secondary metabolism. |
| PubMed:Effect of isoquinoline alkaloids of different structural types on antiplatelet aggregation in vitro. |
| PubMed:Intestinal spasmolytic effects of STW 5 (Iberogast) and its components. |
| PubMed:Large-scale separation of alkaloids from Corydalis decumbens by pH-zone-refining counter-current chromatography. |
| PubMed:Alkaloids from Eschscholzia californica and their capacity to inhibit binding of [3H]8-Hydroxy-2-(di-N-propylamino)tetralin to 5-HT1A receptors in Vitro. |
| PubMed:Protopine inhibits serotonin transporter and noradrenaline transporter and has the antidepressant-like effect in mice models. |
| PubMed:Proapoptotic activity of Ukrain is based on Chelidonium majus L. alkaloids and mediated via a mitochondrial death pathway. |
| PubMed:Identification and quantification of isoquinoline alkaloids in the genus Sarcocapnos by GC-MS. |
| PubMed:Regulation of glutamate level in rat brain through activation of glutamate dehydrogenase by Corydalis ternata. |
| PubMed:Theoretical and experimental NMR study of protopine hydrochloride isomers. |
| PubMed:Effects of protopine on intracellular calcium and the PKC activity of rat aorta smooth muscle. |
| PubMed:[Studies on the alkaloids from the herb of Corydalis adunca]. |
| PubMed:[Determination of protopine and isocorydine in root of Dactylicapnos scandens by HPLC]. |
| PubMed:Effect of binary combination of some plant-derived molluscicides with MGK-264 or piperonyl butoxide on the reproduction of the snail Lymnaea acuminata. |
| PubMed:Acetylcholinesterase inhibitors from the aerial parts of Corydalis speciosa. |
| PubMed:Inhibitory effect of protopine on K(ATP) channel subunits expressed in HEK-293 cells. |
| PubMed:Protopine alkaloids in horse urine. |
| PubMed:1H and 13C NMR signal assignment of benzylisoquinoline alkaloids from Fumaria officinalis L. (Papaveraceae). |
| PubMed:How to treat tremor. |
| PubMed:Cytochrome P450 isoenzymes involved in rat liver microsomal metabolism of californine and protopine. |
| PubMed:Inhibition of mouse liver respiration by Chelidonium majus isoquinoline alkaloids. |
| PubMed:Antifungal activity of the methanolic extract and alkaloids of Glaucium oxylobum. |
| PubMed:Studies on the metabolism and toxicological detection of the Eschscholtzia californica alkaloids californine and protopine in urine using gas chromatography-mass spectrometry. |
| PubMed:In vitro susceptibility of Helicobacter pylori to isoquinoline alkaloids from Sanguinaria canadensis and Hydrastis canadensis. |
| PubMed:Cytotoxic activity and quality control determinations on Chelidonium majus. |
| PubMed:Two new protopines argemexicaines A and B and the anti-HIV alkaloid 6-acetonyldihydrochelerythrine from formosan Argemone mexicana. |
| PubMed:[RP-HPLC method for determination of protopine in plasma and pharmacokinetics in rats]. |
| PubMed:[Concentration of four alkaloids in the aerial parts of Eomecon chionantha from different mounth in year]. |
| PubMed:Direct determination of alkaloid contents in Fumaria species by GC-MS. |
| PubMed:Assay of nematocidal activity of isoquinoline alkaloids using third-stage larvae of Strongyloides ratti and S. venezuelensis. |
| PubMed:Elevational trends in defense chemistry, vegetation, and reproduction in Sanguinaria canadensis. |
| PubMed:A new tetrahydroprotoberberine N-oxide alkaloid and anti-platelet aggregation constituents of Corydalis tashiroi. |
| PubMed:Protopine hydrochloride. |
| PubMed:New protopine alkaloids from Aristolochia constricta reduce morphine withdrawal in vitro. |
| PubMed:Electrophysiological effects of protopine in cardiac myocytes: inhibition of multiple cation channel currents. |
| PubMed:Effect of protopine on cytosolic Ca2+ in rabbit platelets. |
| PubMed:Effect of molluscicidal components of Abrus precatorius, Argemone mexicana and Nerium indicum on certain biochemical parameters of Lymnaea acuminata. |
| PubMed:Protopine from Corydalis ternata has anticholinesterase and antiamnesic activities. |
| PubMed:Antispasmodic and relaxant activity of chelidonine, protopine, coptisine, and Chelidonium majus extracts on isolated guinea-pig ileum. |
| PubMed:An assessment of the potential of protopine to inhibit microsomal drug metabolising enzymes and prevent chemical-induced hepatotoxicity in rodents. |
| PubMed:New protopine and benzyltetrahydroprotoberberine alkaloids from Aristolochia constricta and their activity on isolated guinea-pig ileum. |
| PubMed:Isoquinoline alkaloids from Argemone mexicana reduce morphine withdrawal in guinea pig isolated ileum. |
| PubMed:Anti-thrombotic and anti-inflammatory activities of protopine. |
| PubMed:[Protective action of corynoline, acetylcorynoline and protopine against experimental liver injury in mice]. |
| PubMed:Chelidonium majus L.: components with in vitro affinity for the GABAA receptor. Positive cooperation of alkaloids. |
| PubMed:[Effect of protopine on rabbit platelet function]. |
| PubMed:Opioid, calcium, and adrenergic receptor involvement in protopine analgesia. |
| PubMed:[HPTLC separation and fluorodensitometric determination of isoquinoline alkaloids in Chelidonine majus L]. |
| PubMed:Ca(2+)-channel blockade in rat thoracic aorta by protopine isolated from Corydalis tubers. |
| PubMed:Antihaemostatic and antithrombotic effect of some antiplatelet agents isolated from Chinese herbs. |
| PubMed:Chemical Study on the Alkaloids of Corydalis hsuchowensis. |
| PubMed:Effects of protopine on blood platelet aggregation. III. Effect of protopine on the metabolic system of arachidonic acid in platelets. |
| PubMed:[Isoquinoline alkaloids from Corydalis thyrsiflora prain]. |
| PubMed:Characterization of Sanguinaria canadensis L. fluid extract by FAB mass spectrometry. |
| PubMed:[Relaxant effects of protopine on smooth muscles]. |
| PubMed:Stepwise gradient in thin-layer chromatography of Chelidonium alkaloids. |
| PubMed:Effects of protopine on blood platelet aggregation. II. Effect on metabolic system of adenosine 3',5'-cyclic monophosphate in platelets. |
| PubMed:New hydroxylated benzo[c]phenanthridine alkaloids from Eschscholtzia californica cell suspension cultures. |
| PubMed:Antiplatelet effects of protopine isolated from Corydalis tubers. |
| PubMed:Cytotoxicity of isoquinoline alkaloids and their N-oxides. |
| PubMed:Effects of protopine on blood platelet aggregation; 1. |
| PubMed:In vitro study of the anticholinergic and antihistaminic activities of protopine and some derivatives. |
| PubMed:Chemical Study of Alkaloids from Corydalis bungeana. |
| PubMed:[Effects of alkaloids of Corydalis decumbens on cerebral and peripheral circulation in the dog]. |
| PubMed:Enhancement of gamma-aminobutyric acid receptor binding by protopine-type alkaloids. |
| PubMed:Comparison of chemical and botanical studies of Turkish papaver belonging to the section pilosa. |
| PubMed:[Chemical study on a traditional Tibetan drug Hypecoum leptocarpum]. |
| PubMed:Separation and Quantification of Some Alkaloids from Fumaria parviflora by Capillary Isotachophoresis1. |
| PubMed:[TLC separation and densitometric determination of six isoquinoline alkaloids in Corydalis bungeana]. |
| PubMed:Isoquinoline alkaloids from cell suspension cultures of Fumaria capreolata. |
| PubMed:Alkaloids of Fumaria indica: Further Studies on Narceimine and Narlumidine. |
| PubMed:Beta-phenylethylamines and the isoquinoline alkaloids. |
| PubMed:Alkaloids of Fumaria densiflora*. |
| PubMed:The alkaloids of Corydalis meifolia. |
| PubMed:The alkaloids of Corydalis meifolia. |
| PubMed:Somatic embryogenesis of tissue cultures of Papaver somniferum and Papaver orientale and its relationship to alkaloid and lipid metabolism. |
| PubMed:Alkaloids of Turkish Glaucium species. |
| PubMed:Alkaloids from Fumaria parviflora and F. kralikii. |
| PubMed:Alkaloids of Corydalis slivenensis. |
| PubMed:Alkaloids from Corydalis bulbosa. |
| PubMed:[The antibacterial effects of some alkaloids isolated from Glaucium flavum Crantz]. |
| PubMed:Alkaloids from Corydalis marschalliana. |
| PubMed:[Analgesic and antispastic effects of protopine (author's transl)]. |
| PubMed:Alkaloids from Papaver armeniacum, P. fugax and P. tauricola. |
| PubMed:Variability of alkaloid spectrum in early stages of development of Glaucium flavum Crantz. |
| PubMed:High pressure liquid chromatographic determination of the five major alkaloids in Papaver somniferum L. and thebaine in Papaver bracteatum Lindl. capsular tissue. |
| PubMed:[Prevention of ventricular fibrillation with the aid of protopine in animal experiments]. |
| PubMed:Alkaloids of papaver genus IX. Alkaloids of Glaucium vitellinum Boiss and Buhse, population Seerjan and Glaucium pulchrum Stapf, population Elika. |
| PubMed:Alkaloids of Glaucium flavum Grantz, populations Isfahan and Kazerun. |
| PubMed:Alkaloids of Glaucium oxylobum Boiss and Buhse, Population Ab-Ali. |
| PubMed:[Transformation of indole alkaloids. III. The partial synthesis of protopine type indole alkaloid "burnamicine" (author's transl)]. |
| PubMed:Isolation and chemistry of alkaloids from plants of the family Papaveraceae LXVII: Corydalis cava (L.) Sch. et K. (C. tuberosa DC). |
| PubMed:Antimicrobial agents from higher plants. Additional alkaloids and antimicrobial agents from Thalictrum rugosum. |
| PubMed:[Extractive photometric determination of protopine]. |
| PubMed:The structures of coulteropine and other protopine-type alkaloid acid salts. |
| PubMed:The nuclear resonance spectrum of protopine: rate of racemization and ring inversion. |
| PubMed:Alkaloids of the Papaveraceae. VI. Protopine and allocryptopine from Arctomecon alifornica. |
| PubMed:Phenol oxidation and biosynthesis. 8. Investigations on the biosynthesis of berberine and protopine. |
| PubMed:THE ANTITUMOR FACTORS PRESENT IN CHELIDONIUM MAJUS L. I. CHELIDONINE AND PROTOPINE. |
| PubMed:[Partition of chelidonine and protopine by means of countercurrent cascade extraction]. |
| PubMed:Separation and determination of the dissociation constants of chelidonine and protopine by paper chromatography. |
| PubMed:Origin of the methylenedioxy groups of the alkaloid protopine. |
3D/inchi