|
Category:natural substances and extractives
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Assay: | 95.00 to 100.00
|
| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 1.13400 to 1.13700 @ 20.00 °C.
|
| Pounds per Gallon - (est).: | 9.447 to 9.472
|
| Refractive Index: | 1.64800 to 1.65300 @ 20.00 °C.
|
| Boiling Point: | 220.00 to 221.00 °C. @ 760.00 mm Hg
|
| Boiling Point: | 129.00 to 50.00 °C. @ 0.00 mm Hg
|
| Vapor Pressure: | 0.200000 mmHg @ 25.00 °C. (est) |
| Flash Point: | 190.00 °F. TCC ( 87.78 °C. )
|
| logP (o/w): | 3.280 |
| Soluble in: |
| | water, 89.9 mg/L @ 25 °C (exp) | | | water, 138.6 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| |
| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
| |
| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
intraperitoneal-mouse LD50 100 mg/kg
National Technical Information Service. Vol. AD277-689
oral-mouse LD50 87 mg/kg
KIDNEY, URETER, AND BLADDER: URINE VOLUME INCREASED
Agents and Actions, A Swiss Journal of Pharmacology. Vol. 8, Pg. 610, 1978.
intraperitoneal-rat LDLo 150 mg/kg
Arzneimittel-Forschung. Drug Research. Vol. 16, Pg. 870, 1966.
|
| Dermal Toxicity: |
subcutaneous-mouse LD50 250 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD
Arzneimittel-Forschung. Drug Research. Vol. 5, Pg. 505, 1955.
|
| Inhalation Toxicity: |
|
Not determined
|
Safety in Use Information:
| Category: | | natural substances and extractives |
| Recommendation for phenyl isothiocyanate usage levels up to: | | | not for fragrance use.
|
| |
| Recommendation for phenyl isothiocyanate flavor usage levels up to: |
| | not for flavor use.
|
Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | benzene-1-isothiocyanate | | | benzenisothiocyanate | | | phenyl mustard oil | | | phenyl thioisocyanate | | | phenylisothiocyanate | | iso | thiocyanatobenzene | | iso | thiocyanic acid phenyl ester | | iso | thiocyanic acid, phenyl ester |
Articles:
| PubMed:The role dietary of bioactive compounds on the regulation of histone acetylases and deacetylases: A review. |
| PubMed:Chemical properties in fruits of mulberry species from the Xinjiang province of China. |
| PubMed:Analysis of amino acid composition in proteins of animal tissues and foods as pre-column o-phthaldialdehyde derivatives by HPLC with fluorescence detection. |
| PubMed:A chemical approach for the reduction of beauvericin in a solution model and in food systems. |
| PubMed:Identification of a hepatoprotective peptide in wheat gluten hydrolysate against D-galactosamine-induced acute hepatitis in rats. |
| PubMed:Study of the chemical reduction of the fumonisins toxicity using allyl, benzyl and phenyl isothiocyanate in model solution and in food products. |
| PubMed:Identification of food-derived elastin peptide, prolyl-glycine (Pro-Gly), in human blood after ingestion of elastin hydrolysate. |
| PubMed:Identification of a novel food-derived collagen peptide, hydroxyprolyl-glycine, in human peripheral blood by pre-column derivatisation with phenyl isothiocyanate. |
| PubMed:Isothiocyanate profile and selective antibacterial activity of root, stem, and leaf extracts derived from Raphanus sativus L. |
| PubMed:Acaricidal constituents isolated from Sinapis alba L. seeds and structure-activity relationships. |
| PubMed:Identification of food-derived bioactive peptides in blood and other biological samples. |
| PubMed:Phenethyl isothiocyanate suppresses receptor activator of NF-kappaB ligand (RANKL)-induced osteoclastogenesis by blocking activation of ERK1/2 and p38 MAPK in RAW264.7 macrophages. |
| PubMed:Mass spectrometric detection of attomole amounts of the prion protein by nanoLC/MS/MS. |
| PubMed:Determination of theanine in commercial tea by liquid chromatography with fluorescence and diode array ultraviolet detection. |
| PubMed:Improvement in isolation and identification of food-derived peptides in human plasma based on precolumn derivatization of peptides with phenyl isothiocyanate. |
| PubMed:Determination of amino acids in foods by reversed-phase HPLC with new precolumn derivatives, butylthiocarbamyl, and benzylthiocarbamyl derivatives compared to the phenylthiocarbamyl derivative and ion exchange chromatography. |
| PubMed:Isolation and identification of indigestible pyroglutamyl peptides in an enzymatic hydrolysate of wheat gluten prepared on an industrial scale. |
| PubMed:Analysis of glycated and ascorbylated proteins by gas chromatography-mass spectrometry. |
| PubMed:Method validation study of hypoglycin A determination in ackee fruit. |
| PubMed:Investigation on the formation and the determination of gamma-glutamyl-beta-alanylhistidine and related isopeptide in the macromolecular fraction of beef soup stock. |
| PubMed:Amino acid profile of milk-based infant formulas. |
| PubMed:Effect of hydrolysis time on the determination of amino acids in samples of soybean products with ion-exchange chromatography or precolumn derivatization with phenyl isothiocyanate. |
| PubMed:CS(2) blinds in Brassica crops: false positive results in the dithiocarbamate residue analysis by the acid digestion method. |
| PubMed:Quantitative separation of 4-hydroxyproline from skeletal muscle collagen by micellar electrokinetic capillary electrophoresis. |
| PubMed:Determination of amino acids in the foods by reversed-phase high-performance liquid chromatography with a new precolumn derivative, butylthiocarbamyl amino acid, compared to the conventional phenylthiocarbamyl derivatives and ion-exchange chromatography. |
| PubMed:Isocratic high-performance liquid chromatographic determination of tryptophan in infant formulas. |
| PubMed:Determination of free glutamic acid in a variety of foods by high-performance liquid chromatography. |
| PubMed:The clastogenic effects of isothiocyanates. |
| PubMed:Evaluation of liquid chromatographic analysis of nutritionally important amino acids in food and physiological samples. |
| PubMed:Quantitation of total protein deposits on contact lenses by means of amino acid analysis. |
| PubMed:Comparison of liquid chromatographic method to AOAC microbiological method for determination of L-tryptophan in tablets and capsules. |
| PubMed:Precolumn phenylisothiocyanate derivatization and liquid chromatography of amino acids in food. |
| PubMed:Confirmation of domoic acid in molluscan shellfish by chemical derivatization and reversed-phase liquid chromatography. |
| PubMed:Complete amino acid analysis in hydrolysates of foods and feces by liquid chromatography of precolumn phenylisothiocyanate derivatives. |
| PubMed:Amino acid analysis utilizing phenylisothiocyanate derivatives. |
| PubMed:Measurement of branched chain amino acids in blood plasma by high performance liquid chromatography. |
| PubMed:A new, rapid, high-sensitivity analysis of amino acids in food type samples. |
| PubMed:Four-week toxicity study of phenyl isothiocyanate in rats. |
|
3D/inchi