EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes

3H-2,1-benzoxathiole, 3,3-bis(4-hydroxyphenyl)-, 1,1-dioxide

Supplier Sponsors

CAS Number: 143-74-8Picture of molecule3D/inchi
Other(deleted CASRN):2877-88-5
ECHA EINECS - REACH Pre-Reg:205-609-7
Nikkaji Web:J5.823H
Beilstein Number:0326470
XlogP3:3.00 (est)
Molecular Weight:354.38158000
Formula:C19 H14 O5 S
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome or firefox)
Category:buffering agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
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Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 562.80 °C. @ 760.00 mm Hg (est)
Flash Point: 562.00 °F. TCC ( 294.20 °C. ) (est)
logP (o/w): 3.020
Soluble in:
 water, 770 mg/L @ 100C (exp)
 water, 58.41 mg/L @ 25 °C (est)
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: buffering agents
Abbey Color
Phenol Red Dye
Odor: characteristic
Use: Abbey Color is a leading manufacturer of phenol red dye. Phenol red is a water-soluble dye used as a pH indicator, changing from yellow to red over pH 6.6 to 8.0, and then turning a bright pink color above pH 8.1. As such, phenol red can be used as a pH indicator dye in various medical and cell biology tests.
BOC Sciences
For experimental / research use only.
Phenolsulfonphthalein 95%
ECSA Chemicals
EMD Millipore
For experimental / research use only.
Phenol Red
Glentham Life Sciences
Phenol Red
Santa Cruz Biotechnology
For experimental / research use only.
Phenol Red ≥95%
For experimental / research use only.
Phenol Red powder, BioReagent, suitable for cell culture
For experimental / research use only.
Phenol Red
Universal Preserv-A-Chem Inc.
Safety Information:
Preferred SDS: View
Hazards identification
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
intravenous-mouse LD50 1368 mg/kg
Drugs in Japan Vol. -, Pg. 930, 1990.

intravenous-rat LD50 752 mg/kg
Drugs in Japan Vol. -, Pg. 930, 1990.

Dermal Toxicity:
subcutaneous-rat LD50 > 600 mg/kg
Clinical Toxicology. Vol. 4(2), Pg. 185, 1971.

Inhalation Toxicity:
Not determined
Safety in Use Information:
buffering agents
Recommendation for phenolsulfonphthalein usage levels up to:
 not for fragrance use.
Recommendation for phenolsulfonphthalein flavor usage levels up to:
 not for flavor use.
Safety References:
EPI System: View
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA GENetic TOXicology:Search
EPA Substance Registry Services (TSCA):143-74-8
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :4766
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
RTECS:SJ7490000 for cas# 143-74-8
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:143-74-8
Pubchem (cid):4766
Pubchem (sid):134973933
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
KEGG (GenomeNet):C12600
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2930.90.2900
Potential Blenders and core components note
None Found
Potential Uses:
None Found
Occurrence (nature, food, other):note
 not found in nature
4,4'-(3H-2,1-benzoxathiol-3-ylidene)bisphenol S,S-dioxide
4,4'-(3H,2,1-benzoxathiol-3-ylidene)bisphenol S,S-dioxide
4,4'-(3H-2,1-benzoxathiol-3-ylidene)diphenol S,S-dioxide
3H-2,1-benzoxathiole, 3,3-bis(4-hydroxyphenyl)-, 1,1-dioxide
a-hydroxy-a,a-bis(p-hydroxyphenyl)-o-toluenesulfonic acid g-sultone
3,3-bis(p-hydroxyphenyl)-3H-2,1-benzoxathiole 1,1-dioxide
 phenol red
 phenol, 4,4-(3H-2, 1-benzoxathiol-3-ylidene)di-, S-S-dioxide
 phenol, 4,4-(3H-2, 1-benzoxathiol-3-ylidene)di-, S,S-dioxide
 phenol, 4,4-(3H-2,1-benzoxathiol-3-ylidene)di-, S-S-dioxide
 phenol, 4,4'-(1,1-dioxido-3H-2,1-benzoxathiol-3-ylidene)bis-
 phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis-, (S,S-dioxide)
 phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis-, S,S-dioxide
 phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)bis-,S,S-dioxide (9CI)
 phenol, 4,4'-(3H-2,1-benzoxathiol-3-ylidene)di-, S,S-dioxide


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PubMed:Development of a medium for differentiation between Escherichia coli and Escherichia coli O157:H7.
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PubMed:Evaluation of the effects of varying solute content on the efficacy of oral rehydration solutions in a rat model of secretory diarrhoea.
PubMed:[The detection of salmonellas using Rambach agar].
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PubMed:Evidence for a new extracellular peroxidase. Manganese-inhibited peroxidase from the white-rot fungus Bjerkandera sp. BOS 55.
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red dye, ph indicator, and diagnostic aid for determination of renal function. it is used also for studies of the gastrointestinal and other systems.
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