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pancreatin from porcine pancreas
pancreatic enzymes

Supplier Sponsors

CAS Number: 8049-47-6
Other(deleted CASRN):9002-16-8
ECHA EC Number:232-468-9
MDL:MFCD00131789
Formula:unspecified
Category:enzyme preparations and microorganisms
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
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FDA Mainterm (SATF):8049-47-6 ; PANCREATIN
FDA Regulation:
FDA PART 184 -- DIRECT FOOD SUBSTANCES AFFIRMED AS GENERALLY RECOGNIZED AS SAFE
Subpart B--Listing of Specific Substances Affirmed as GRAS
Sec. 184.1583 Pancreatin.
 
Physical Properties:
Food Chemicals Codex Listed: No
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: hair conditioning
skin conditioning
 
Suppliers:
American Laboratories
Pancreatin 3X USP Powder 485
American Laboratories
Pancreatin 3X USP Powder 524
American Laboratories
Pancreatin 4X Powder 92B
American Laboratories
Pancreatin 4X USP Granular 698
American Laboratories
Pancreatin 4X USP Powder 512
American Laboratories
Pancreatin 4X USP Powder 632
American Laboratories
Pancreatin 5X USP Powder 26C
American Laboratories
Pancreatin 5X USP Powder 552
American Laboratories
Pancreatin 6X USP 525
American Laboratories
Pancreatin 6X USP Powder 85B
American Laboratories
Pancreatin 8X Powder 312
American Laboratories
Pancreatin 8X USP Granular 693
American Laboratories
Pancreatin 8X USP Powder 523
American Laboratories
Pancreatin Full Strength Granular 28C
American Laboratories
Pancreatin Full Strength Granular 671
American Laboratories
Pancreatin Full Strength Powder 059
American Laboratories
Pancreatin Full Strength Powder 337
American Laboratories
Pancreatin USP Powder 487
American Laboratories
Pancreatin USP Powder 88B
George Uhe Company
pancreatin
Pangaea Sciences
Pancreatin NF
Penta International
PANCREATIN USP
Sigma-Aldrich: Sigma
For experimental / research use only.
Pancreatin from porcine pancreas 8 USP specifications
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
oral-rat LD50 > 10000 mg/kg
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.

intraperitoneal-rat LD50 2550 mg/kg
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.

oral-mouse LD50 > 10000 mg/kg
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.

intraperitoneal-mouse LD50 2100 mg/kg
BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) SENSE ORGANS AND SPECIAL SENSES: PTOSIS: EYE
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.

Dermal Toxicity:
subcutaneous-rat LD50 > 5000 mg/kg
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.

subcutaneous-mouse LD50 3870 mg/kg
SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Yakuri to Chiryo. Pharmacology and Therapeutics. Vol. 3, Pg. 2427, 1975.

Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
enzyme preparations and microorganisms
Recommendation for pancreatin from porcine pancreas usage levels up to:
 not for fragrance use.
 
Recommendation for pancreatin from porcine pancreas flavor usage levels up to:
 not for flavor use.
 
Safety References:
ClinicalTrials.gov:search
Daily Med:search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):8049-47-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:1
Chemidplus:0008049476
RTECS:RT9033000 for cas# 8049-47-6
 
References:
Pubchem (sid):135348268
 
Other Information:
FDA Substances Added to Food (formerly EAFUS):View
HMDB (The Human Metabolome Database):Search
FooDB:FDB001106
Export Tariff Code:3507.90.0000
FDA Listing of Food Additive Status:View
VCF-Online:VCF Volatile Compounds in Food
Wikipedia:View
Wikipedia2:View2
 
Potential Blenders and core components note
None Found
 
Potential Uses:
 biological additives
 
Occurrence (nature, food, other):note
 banana fruit
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 cacao bean
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 fig latex
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 flax seed
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 horseradish root
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 pancreatin
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 pepper black pepper fruit
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 pepper black pepper seed
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 poppy opium poppy latex
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 soybean seed
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 wheat seed
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Synonyms:
 pancreatic enzymes
 pancrelipase
 

Articles:

PubMed:Neutralizing effect of hemolymph from the shore crab, Thalamita crenata, on paralytic shellfish toxins.
PubMed:Does boiling affect the bioaccessibility of selenium from cabbage?
PubMed:Carboxymethyl-starch/alginate microspheres containing diamine oxidase for intestinal targeting.
PubMed:Characterization and Comparison of Protein and Peptide Profiles and their Biological Activities of Improved Common Bean Cultivars (Phaseolus vulgaris L.) from Mexico and Brazil.
PubMed:An identified antioxidant peptide obtained from ostrich (Struthio camelus) egg white protein hydrolysate shows wound healing properties.
PubMed:Binding of bile acids by pastry products containing bioactive substances during in vitro digestion.
PubMed:Preparation and characterization of debranched-starch/phosphatidylcholine inclusion complexes.
PubMed:Purification, characterization and safety assessment of the introduced cold shock protein B in DroughtGard™ maize.
PubMed:Beneficial effects of simulated gastro-intestinal digests of fried egg and its fractions on blood pressure, plasma lipids and oxidative stress in spontaneously hypertensive rats.
PubMed:Impact of commercial precooking of common bean (Phaseolus vulgaris) on the generation of peptides, after pepsin-pancreatin hydrolysis, capable to inhibit dipeptidyl peptidase-IV.
PubMed:Effect of heat-moisture treatment on digestibility of different cultivars of sweet potato (Ipomea batatas (L.) Lam) starch.
PubMed:Degradation and antioxidant activities of peptides and zinc-peptide complexes during in vitro gastrointestinal digestion.
PubMed:Immunoreactivity of lactic acid-treated mare's milk after simulated digestion.
PubMed:In vitro enzymic hydrolysis of chlorogenic acids in coffee.
PubMed:Probiotic potential of lactic acid bacteria present in home made curd in southern India.
PubMed:Edible bird's nest ameliorates oxidative stress-induced apoptosis in SH-SY5Y human neuroblastoma cells.
PubMed:Microencapsulation of Probiotics by Calcium Alginate-gelatinized Starch with Chitosan Coating and Evaluation of Survival in Simulated Human Gastro-intestinal Condition.
PubMed:Angiotensin I converting enzyme inhibitory peptides obtained after in vitro hydrolysis of pea (Pisum sativum var. Bajka) globulins.
PubMed:Release of β-casomorphin-7/5 during simulated gastrointestinal digestion of milk β-casein variants from Indian crossbred cattle (Karan Fries).
PubMed:In vitro fermentation of spent turmeric powder with a mixed culture of pig faecal bacteria.
PubMed:The in vitro digestibility of beef varies with its inherent ultimate pH.
PubMed:Pepsin-pancreatin protein hydrolysates from extruded amaranth inhibit markers of atherosclerosis in LPS-induced THP-1 macrophages-like human cells by reducing expression of proteins in LOX-1 signaling pathway.
PubMed:Effect of heat processing on selected grain amaranth physicochemical properties.
PubMed:A standardised static in vitro digestion method suitable for food - an international consensus.
PubMed:Release of Antioxidant Capacity from Five Plant Foods during a Multistep Enzymatic Digestion Protocol.
PubMed:Physical, chemical and biochemical properties of casein hydrolyzed by three proteases: partial characterizations.
PubMed:Fortification of white flat bread with sprouted red kidney bean (Phaseolus vulgaris).
PubMed:Enzymatic hydrolysis of starch in the presence of cereal soluble fibre polysaccharides.
PubMed:Peptides in pepsin-pancreatin hydrolysates from commercially available soy products that inhibit lipopolysaccharide-induced inflammation in macrophages.
PubMed:Extrusion improved the anti-inflammatory effect of amaranth (Amaranthus hypochondriacus) hydrolysates in LPS-induced human THP-1 macrophage-like and mouse RAW 264.7 macrophages by preventing activation of NF-κB signaling.
PubMed:In vitro antioxidant properties of chicken skin enzymatic protein hydrolysates and membrane fractions.
PubMed:Characterization of lactic acid bacteria isolated from infant faeces as potential probiotic starter cultures for fermented sausages.
PubMed:Elaboration and characterization of barley protein nanoparticles as an oral delivery system for lipophilic bioactive compounds.
PubMed:Isolation and identification of antioxidant peptides from commercial soybean-based infant formulas.
PubMed:Effects of malondialdehyde modification on the in vitro digestibility of soy protein isolate.
PubMed:Antioxidant properties of Australian canola meal protein hydrolysates.
PubMed:Physicochemical property of starch-pectin conjugates with resistance to enzymatic activity.
PubMed:Characterisation of different digestion susceptibility of lupin seed globulins.
PubMed:Evaluation of amorphous debranched starch as extended-release matrices in tablets.
PubMed:Influence of the matrix in bioavailability of flufenoxuron, lufenuron, pyriproxyfen and fenoxycarb residues in grapes and wine.
PubMed:Glycinyl-histidinyl-serine (GHS), a novel rapeseed protein-derived peptide has blood pressure-lowering effect in spontaneously hypertensive rats.
PubMed:Effect of protein oxidation on the in vitro digestibility of soy protein isolate.
PubMed:Simultaneous production of multi-functional peptides by pancreatic hydrolysis of bovine casein in an enzymatic membrane reactor via combinational chromatography.
PubMed:Effect of citric acid deamidation on in vitro digestibility and antioxidant properties of wheat gluten.
PubMed:Physicochemical behaviour of WPI-stabilized emulsions in in vitro gastric and intestinal conditions.
PubMed:Antihypertensive and free radical scavenging properties of enzymatic rapeseed protein hydrolysates.
PubMed:Effect of simulated gastric and intestinal digestion on temporal stability and immunoreactivity of peanut, almond, and pine nut protein allergens.
PubMed:Effect of the structural features of hydrochloric acid-deamidated wheat gluten on its susceptibility to enzymatic hydrolysis.
PubMed:Cytotoxicity of α-dicarbonyl compounds submitted to in vitro simulated digestion process.
PubMed:Fermentation profiles of wheat dextrin, inulin and partially hydrolyzed guar gum using an in vitro digestion pretreatment and in vitro batch fermentation system model.
PubMed:Characterization of Tyr-Leu-Gly, a novel anxiolytic-like peptide released from bovine αS-casein.
PubMed:Simulated digestion of proanthocyanidins in grape skin and seed extracts and the effects of digestion on the angiotensin I-converting enzyme (ACE) inhibitory activity.
PubMed:Detection of key factors affecting lycopene in vitro accessibility.
PubMed:Release of EPA and DHA from salmon oil - a comparison of in vitro digestion with human and porcine gastrointestinal enzymes.
PubMed:Interaction of curcumin with phosphocasein micelles processed or not by dynamic high-pressure.
PubMed:Development of a standardised human in vitro digestion protocol based on macronutrient digestion using response surface methodology.
PubMed:Influence of in vitro simulated gastroduodenal digestion on methylglyoxal concentration of Manuka ( Lectospermum scoparium ) honey.
PubMed:Degradation and fermentation characteristics of wheat coproducts from flour milling in the pig intestine studied in vitro.
PubMed:Stability during in vitro digestion of lactoferrin-loaded liposomes prepared from milk fat globule membrane-derived phospholipids.
PubMed:The effect of thermal and ultrasonic treatment on amino acid composition, radical scavenging and reducing potential of hydrolysates obtained from simulated gastrointestinal digestion of cowpea proteins.
PubMed:Defatted Jatropha curcas flour and protein isolate as materials for protein hydrolysates with biological activity.
PubMed:Binding affinity between dietary polyphenols and β-lactoglobulin negatively correlates with the protein susceptibility to digestion and total antioxidant activity of complexes formed.
PubMed:Probiotic potential of Lactobacillus spp. isolated from Brazilian regional ovine cheese.
PubMed:Selection of dominant NSLAB from a mature traditional cheese according to their technological properties and in vitro intestinal challenges.
PubMed:Characterization of the nutritive value of tropical legume grains as alternative ingredients for small-scale pork producers using in vitro enzymatic hydrolysis and fermentation.
PubMed:The type and concentration of milk increase the in vitro bioaccessibility of coffee chlorogenic acids.
PubMed:Physiochemical properties and prolonged release behaviours of chitosan-denatured β-lactoglobulin microcapsules for potential food applications.
PubMed:Mechanism of hydrolysis of native and cooked starches from different botanical sources in the presence of tea extracts.
PubMed:Stability of Polyphenols Epigallocatechin Gallate and Pentagalloyl Glucose in a Simulated Digestive System.
PubMed:Iron-chelating activity of chickpea protein hydrolysate peptides.
PubMed:Survival of microencapsulated probiotic Lactobacillus paracasei LBC-1e during manufacture of Mozzarella cheese and simulated gastric digestion.
PubMed:Antioxidant and metal chelating activities of peptide fractions from phaseolin and bean protein hydrolysates.
PubMed:Yeasts from Colombian Kumis as source of peptides with Angiotensin I converting enzyme (ACE) inhibitory activity in milk.
PubMed:Preparation of human milk fat substitutes from palm stearin with arachidonic and docosahexaenoic acid: combination of enzymatic and physical methods.
PubMed:In vitro study of triglyceride lipolysis and phase distribution of the reaction products and cholesterol: effects of calcium and bicarbonate.
PubMed:The influence of environmental factors on the adhesion of combinations of probiotics to rice fibre fractions.
PubMed:Residual carbohydrates from in vitro digested processed rapeseed ( Brassica napus ) meal.
PubMed:In vitro digestion rate and estimated glycemic index of oat flours from typical and high β-glucan oat lines.
PubMed:Investigation of the susceptibility of acid-deamidated wheat gluten to in vitro enzymatic hydrolysis using Raman spectra and free amino acid analysis.
PubMed:Angiotensin-I converting enzyme inhibitory and antioxidant activities of egg protein hydrolysates produced with gastrointestinal and nongastrointestinal enzymes.
PubMed:Development and characterization of coated-microparticles based on whey protein/alginate using the Encapsulator device.
PubMed:Effect of prebiotic carbohydrates on the growth and tolerance of Lactobacillus.
PubMed:Behavior of almond oil bodies during in vitro gastric and intestinal digestion.
PubMed:Angiotensin-converting enzyme inhibitory and antioxidative activities and functional characterization of protein hydrolysates of hard-to-cook chickpeas.
PubMed:Digestive stability of hydroxytyrosol, hydroxytyrosyl acetate and alkyl hydroxytyrosyl ethers.
PubMed:Release of flavonoids from lupin globulin proteins during digestion in a model system.
PubMed:The influence of selected hypotensive drugs on the bioavailability of minerals from buckwheat groats in vitro enzymatic digestion.
PubMed:Antioxidant activity of protein hydrolysates from aqueous extract of velvet antler (Cervus elaphus) as influenced by molecular weight and enzymes.
PubMed:New Zealand green-lipped mussels (Perna canaliculus) enhance non-haem iron absorption in vitro.
PubMed:Enzyme-assisted extraction for the HPLC determination of ochratoxin A in pork and dry-cured ham.
PubMed:Heating chicken breast muscle reduces the amount of dialyzable iron after extraction and digestion.
PubMed:New starch preparations resistant to enzymatic digestion.
PubMed:Enhanced survival of probiotic Lactobacillus acidophilus by encapsulation with nanostructured polyelectrolyte layers through layer-by-layer approach.
PubMed:Antioxidant activities and functional properties of grass carp (Ctenopharyngodon idellus) protein hydrolysates.
PubMed:Common bean (Phaseolus vulgaris L.) hydrolysates inhibit inflammation in LPS-induced macrophages through suppression of NF-κB pathways.
PubMed:Relative gene expression of bile salt hydrolase and surface proteins in two putative indigenous Lactobacillus plantarum strains under in vitro gut conditions.
PubMed:Purification and characterisation of angiotensin I converting enzyme (ACE) inhibitory peptides derived from enzymatic hydrolysate of ovotransferrin.
PubMed:Microbiological characteristics of kumis, a traditional fermented Colombian milk, with particular emphasis on enterococci population.
PubMed:Inhibition of buckwheat starch digestion by the formation of starch/bile salt complexes: possibility of its occurrence in the intestine.
PubMed:Partial characterization of proteins from baru (Dipteryx alata Vog) seeds.
PubMed:Behaviour of protein-stabilised emulsions under various physiological conditions.
PubMed:Lyophilization decreases the formation of dialyzable iron by extraction and digestion of chicken breast muscle.
PubMed:Bioaccessibility of carotenoids and vitamin e from pasta: evaluation of an in vitro digestion model.
PubMed:A reliable method to determine methylmercury and ethylmercury simultaneously in foods by gas chromatography with inductively coupled plasma mass spectrometry after enzymatic and acid digestion.
PubMed:The effect of a brief salivary α-amylase exposure during chewing on subsequent in vitro starch digestion curve profiles.
PubMed:Fatty acids, epicatechin-dimethylgallate, and rutin interact with buckwheat starch inhibiting its digestion by amylase: implications for the decrease in glycemic index by buckwheat flour.
PubMed:Deactivation of soybean agglutinin by enzymatic and other physical treatments.
PubMed:Iron uptake by Caco-2 cells following in vitro digestion: effects of heat treatments of pork meat and pH of the digests.
PubMed:[Discriminant function analysis in the assessment of laboratory test data in the correction of traditional therapy for mild icteric form of viral hepatitis B in children with food allergy].
PubMed:Naturally occurring 2-substituted (1,3)-beta-D-glucan producing Lactobacillus suebicus and Pediococcus parvulus strains with potential utility in the production of functional foods.
PubMed:Angiotensin-I converting enzyme inhibitory and antioxidant activities of peptide fractions extracted by ultrafiltration of cowpea Vigna unguiculata hydrolysates.
PubMed:Dietary glycosaminoglycans interfere in bacterial adhesion and gliadin-induced pro-inflammatory response in intestinal epithelial (Caco-2) cells.
PubMed:Effects of phytases and dehulling treatments on in vitro iron and zinc bioavailability in faba bean (Vicia faba L.) flour and legume fractions.
PubMed:Influence of blade tenderization, moisture enhancement and pancreatin enzyme treatment on the processing characteristics and tenderness of beef semitendinosus muscle.
PubMed:Characterization of peptides released by in vitro digestion of pork meat.
PubMed:Fractionation and evaluation of radical-scavenging peptides from in vitro digests of buckwheat protein.
PubMed:Actinidin enhances protein digestion in the small intestine as assessed using an in vitro digestion model.
PubMed:Efficacy and tolerability of a new formulation of pancrelipase delayed-release capsules in children aged 7 to 11 years with exocrine pancreatic insufficiency and cystic fibrosis: a multicenter, randomized, double-blind, placebo-controlled, two-period crossover, superiority study.
PubMed:Coated whey protein/alginate microparticles as oral controlled delivery systems for probiotic yeast.
PubMed:Angiotensin I-converting enzyme inhibitory peptides generated from in vitro gastrointestinal digestion of pork meat.
PubMed:Probiotic properties of yeasts isolated from chicken feces and kefirs.
PubMed:Lunasin, with an arginine-glycine-aspartic acid motif, causes apoptosis to L1210 leukemia cells by activation of caspase-3.
PubMed:Hydroxypropylated starches of varying amylose contents as sustained release matrices in tablets.
PubMed:Changes in antioxidative capacity of saithe (Pollachius virens) and shrimp (Pandalus borealis) during in vitro digestion.
PubMed:Angiotensin-I converting enzyme inhibitory activity of hydrolysates from oat (Avena sativa) proteins by in silico and in vitro analyses.
PubMed:In vitro digestibility of beta-casein and beta-lactoglobulin under simulated human gastric and duodenal conditions: a multi-laboratory evaluation.
PubMed:Fragment analogs as better mimics of obestatin.
PubMed:Susceptibility of lupin gamma-conglutin, the plasma glucose-lowering protein of lupin seeds, to proteolytic enzymes.
PubMed:In vitro digestibility techniques to predict apparent total tract energy digestibility of wheat in grower pigs.
PubMed:Characterization and ACE-inhibitory activity of amaranth proteins.
PubMed:Bioavailability of insect growth regulator residues in citrus.
PubMed:Molecular and probiotic characterization of bacteriocin-producing Enterococcus faecium strains isolated from nonfermented animal foods.
PubMed:Assessing potential effects of inulin and probiotic bacteria on Fe availability from common beans (Phaseolus vulgaris L.) to Caco-2 cells.
PubMed:Antioxidant and bile acid binding activity of buckwheat protein in vitro digests.
PubMed:Comparison of WHO and US FDA biowaiver dissolution test conditions using bioequivalent doxycycline hyclate drug products.
PubMed:Bowman-Birk inhibitor and genistein among soy compounds that synergistically inhibit nitric oxide and prostaglandin E2 pathways in lipopolysaccharide-induced macrophages.
PubMed:Bioaccessibility of phenols in common beans ( Phaseolus vulgaris L.) and iron (Fe) availability to Caco-2 cells.
PubMed:Glucose release of water-soluble starch-related alpha-glucans by pancreatin and amyloglucosidase is affected by the abundance of alpha-1,6-glucosidic linkages.
PubMed:Beta-conglycinin embeds active peptides that inhibit lipid accumulation in 3T3-L1 adipocytes in vitro.
PubMed:In vitro analysis of protection of the enzyme bile salt hydrolase against enteric conditions by whey protein-gum arabic microencapsulation.
PubMed:Improving digestibility of soy flour by reducing disulfide bonds with thioredoxin.
PubMed:Angiotensin-converting enzyme inhibition and free-radical scavenging properties of cationic peptides derived from soybean protein hydrolysates.
PubMed:Identification and characterization of topoisomerase II inhibitory peptides from soy protein hydrolysates.
PubMed:In vitro approaches to assess bioavailability and human gastrointestinal mobilization of food-borne polychlorinated biphenyls (PCBs).
PubMed:Prediction of in vivo apparent total tract energy digestibility of barley in grower pigs using an in vitro digestibility technique.
PubMed:Structural and functional properties of amylose complexes with genistein.
PubMed:In vitro bioavailability of phenolic compounds from five cultivars of frozen sweet cherries (Prunus avium L.).
PubMed:Bioavailability of insect growth regulators in citrus and stone fruits.
PubMed:Reducing, radical scavenging, and chelation properties of in vitro digests of alcalase-treated zein hydrolysate.
PubMed:Utilisation of Chlorella vulgaris cell biomass for the production of enzymatic protein hydrolysates.
PubMed:Esters of 3-chloro-1,2-propanediol (3-MCPD) in vegetable oils: significance in the formation of 3-MCPD.
PubMed:Susceptibility of phaseolin to in vitro proteolysis is highly variable across common bean varieties (Phaseolus vulgaris).
PubMed:Rubimetide (Met-Arg-Trp) derived from Rubisco exhibits anxiolytic-like activity via the DP1 receptor in male ddY mice.
PubMed:Met-Arg-Trp derived from Rubisco lowers blood pressure via prostaglandin D(2)-dependent vasorelaxation in spontaneously hypertensive rats.
PubMed:Effect of liquid pancreatic enzymes on the assimilation of fat in different liquid formula diets.
PubMed:Investigations into inhibitor type and mode, simulated gastrointestinal digestion, and cell transport of the angiotensin I-converting enzyme-inhibitory peptides in Pacific hake (Merluccius productus) fillet hydrolysate.
PubMed:A gene-shuffled glyphosate acetyltransferase protein from Bacillus licheniformis (GAT4601) shows no evidence of allergenicity or toxicity.
PubMed:Cancer-preventive peptide lunasin from Solanum nigrum L. inhibits acetylation of core histones H3 and H4 and phosphorylation of retinoblastoma protein (Rb).
PubMed:Changes in the antioxidative property of herring (Clupea harengus) press juice during a simulated gastrointestinal digestion.
PubMed:Iron-binding properties, amino acid composition, and structure of muscle tissue peptides from in vitro digestion of different meat sources.
PubMed:Catechin degradation with concurrent formation of homo- and heterocatechin dimers during in vitro digestion.
PubMed:Common tea formulations modulate in vitro digestive recovery of green tea catechins.
PubMed:Screening of bifidobacteria with acquired tolerance to human gastrointestinal tract.
PubMed:Porphyran as a functional modifier of a soybean protein isolate through conjugation by the Maillard reaction.
PubMed:Dialyzability of minerals in corn masa gruel (atole) fortified with different iron compounds: effects of ascorbic acid, disodium EDTA, and phytic acid.
PubMed:Ruminal and intestinal degradability of distillers grains plus solubles varies by source.
PubMed:Prediction of digestible energy content of extruded dog food by in vitro analyses.
PubMed:Non-haem iron availability from pork meat: Impact of heat treatments and meat protein dose.
PubMed:Improvement of digestibility, reduction in allergenicity, and induction of oral tolerance of wheat gliadin by deamidation.
PubMed:Expression of the mucus adhesion genes Mub and MapA, adhesion-like factor EF-Tu and bacteriocin gene plaA of Lactobacillus plantarum 423, monitored with real-time PCR.
PubMed:Production of rice protein by alkaline extraction improves its digestibility.
PubMed:Validation and application of a stability-indicating HPLC method for the in vitro determination of gastric and intestinal stability of venlafaxine.
PubMed:Probiotic preparation has the capacity to hydrolyze proteins responsible for wheat allergy.
PubMed:In vitro assessment of properties associated with the survival through the gastro-intestinal tract of staphylococci isolated from traditional sausage fermentation.
PubMed:Up-regulation of tumor suppressor carcinoembryonic antigen-related cell adhesion molecule 1 in human colon cancer Caco-2 cells following repetitive exposure to dietary levels of a polyphenol-rich chokeberry juice.
PubMed:[Enzymatic hydrolysate of soy protein isolate. Preparation and characterization].
PubMed:[Conservative therapy of chronic pancreatitis].
PubMed:Role of colanic acid exopolysaccharide in the survival of enterohaemorrhagic Escherichia coli O157:H7 in simulated gastrointestinal fluids.
PubMed:The effects of alpha-lactalbumin and glycomacropeptide on the association of CaCo-2 cells by enteropathogenic Escherichia coli, Salmonella typhimurium and Shigella flexneri.
PubMed:Food-protein enzymatic hydrolysates possess both antimicrobial and immunostimulatory activities: a "cause and effect" theory of bifunctionality.
PubMed:An elemental diet controls inflammation in indomethacin-induced small bowel disease in rats: the role of low dietary fat and the elimination of dietary proteins.
PubMed:Effect of different hydrolysates of whey protein on hepatic glutathione content in mice.
PubMed:Production and characterization of a soy protein-derived angiotensin I-converting enzyme inhibitory hydrolysate.
PubMed:Arsenosugars in raw and cooked edible seaweed: characterization and bioaccessibility.
PubMed:In vitro determination of calcium bioavailability of milk, dairy products and infant formulas.
PubMed:In vitro determination of the release kinetics of peptides and free amino acids during the digestion of food proteins.
PubMed:Bioavailability of iron from spinach using an in vitro/human Caco-2 cell bioassay model.
PubMed:Angiotensin I converting enzyme inhibitory peptides from in vitro pepsin-pancreatin digestion of soy protein.
PubMed:A comparison of the test tube and the dialysis tubing in vitro methods for estimating the bioavailability of phosphorus in feed ingredients for swine.
PubMed:Importance of S-layer proteins in probiotic activity of Lactobacillus acidophilus M92.
PubMed:Utilization of amylose-lipid complexes as molecular nanocapsules for conjugated linoleic Acid.
PubMed:The in vitro hydrolysis of phytosterol conjugates in food matrices by mammalian digestive enzymes.
PubMed:Iron availability from whey protein hydrogels: an in vitro study.
PubMed:Exfoliation of Helicobacter pylori from gastric mucin by glycopolypeptides from buttermilk.
PubMed:Identification of angiotensin-I-converting enzyme inhibitory peptides derived from sodium caseinate hydrolysates produced by Lactobacillus helveticus NCC 2765.
PubMed:Resistant starch fraction prepared from kintoki bean affects gene expression of genes associated with cholesterol metabolism in rats.
PubMed:An epoxide-furanoid rearrangement of spinach neoxanthin occurs in the gastrointestinal tract of mice and in vitro: formation and cytostatic activity of neochrome stereoisomers.
PubMed:Antihypertensive properties of spinach leaf protein digests.
PubMed:Purification of an ACE inhibitory peptide after hydrolysis of sunflower (Helianthus annuus L.) protein isolates.
PubMed:A simple in vitro test tube method for estimating the bioavailability of phosphorus in feed ingredients for swine.
PubMed:The effect of pH, time and dietary source of cadmium on the bioaccessibility and adsorption of cadmium to/from lettuce (Lactuca sativa L. cv. Ostinata).
PubMed:Antioxidative activity and protective effect against ethanol-induced gastric mucosal damage of a potato protein hydrolysate.
PubMed:In vitro gastrointestinal digestion study of broccoli inflorescence phenolic compounds, glucosinolates, and vitamin C.
PubMed:Postprandial carbohydrate metabolism in healthy subjects and those with type 2 diabetes fed starches with slow and rapid hydrolysis rates determined in vitro.
PubMed:Improvement of the digestibility of the proteins of the red alga Palmaria palmata by physical processes and fermentation.
PubMed:An in vitro model system to predict the bioaccessibility of heterocyclic amines from a cooked meat matrix.
PubMed:Treatment of pancreatic exocrine deficiency.
PubMed:Estimation of arsenic bioaccessibility in edible seaweed by an in vitro digestion method.
PubMed:Stability of recombinant human alpha-1-antitrypsin produced in rice in infant formula.
PubMed:Isolation and antihypertensive effect of angiotensin I-converting enzyme (ACE) inhibitory peptides from spinach Rubisco.
PubMed:Effect of processing on nutritionally important starch fractions in rice varieties.
PubMed:Weaning and feed intake alter pancreatic enzyme activities and corresponding mRNA levels in 7-d-old piglets.
PubMed:[Effect of pretreatment on the measurement of folate in foods].
PubMed:Isolation and identification of indigestible pyroglutamyl peptides in an enzymatic hydrolysate of wheat gluten prepared on an industrial scale.
PubMed:[Estimation of potentially available protein in infant starting formulas for term and preterm neonates].
PubMed:Transport of amino acids from in vitro digested legume proteins or casein in Caco-2 cell cultures.
PubMed:Design of a highly potent anti-hypertensive peptide based on ovokinin(2-7).
PubMed:Pancreatic enzymes: a new group of antiallergic drugs?
PubMed:Estimation of carotenoid accessibility from carrots determined by an in vitro digestion method.
PubMed:IgE-mediated allergy to corn: a 50 kDa protein, belonging to the Reduced Soluble Proteins, is a major allergen.
PubMed:In vitro gastrointestinal digestion study of pomegranate juice phenolic compounds, anthocyanins, and vitamin C.
PubMed:[Dose-dependent effect of pancreatin replacement upon the pancreatic function in the period after pancreatic surgery].
PubMed:Inhibition of proteolysis in oxidized lipid-damaged proteins.
PubMed:Adhesion of bifidobacteria to granular starch and its implications in probiotic technologies.
PubMed:Resistance of feed enzymes to proteolytic inactivation by rumen microorganisms and gastrointestinal proteases.
PubMed:Dephosphorylation of sodium caseinate, enzymatically hydrolyzed casein and casein phosphopeptides by intestinal alkaline phosphatase: implications for iron availability.
PubMed:Iron availability from iron-fortified spirulina by an in vitro digestion/Caco-2 cell culture model.
PubMed:The exacerbation of pancreatic endocrine dysfunction by potent pancreatic exocrine supplements in patients with chronic pancreatitis.
PubMed:In vitro availability of flavonoids and other phenolics in orange juice.
PubMed:Toxicity and mutagenicity studies of DN-50000((R)) and RP-1((R)) enzymes.
PubMed:Enzymatic hydrolysis, grease permeation, and water barrier properties of zein isolate coated paper.
PubMed:[Effect of pancreatin replacement on pancreatic function in the postoperative period after pancreatic surgery].
PubMed:Development of an in vitro digestion method to assess carotenoid bioavailability from meals.
PubMed:Susceptibility of wheat and Aspergillus niger phytases to inactivation by gastrointestinal enzymes.
PubMed:Modulation of immune function by a modified bovine whey protein concentrate.
PubMed:Gastric emptying and intestinal transit of pancreatic enzyme supplements in cystic fibrosis.
PubMed:Digestibility index and factors affecting rate of starch digestion in vitro in conventional food preparation.
PubMed:Defects of cholecystokinin (CCK)-A receptor gene expression and CCK-A receptor-mediated biological functions in Otsuka Long-Evans Tokushima Fatty (OLETF) rats.
PubMed:The use of dual-isotope imaging to compare the gastrointestinal transit of food and pancreatic enzyme pellets in cystic fibrosis patients.
PubMed:Caco-2 cell ferritin formation predicts nonradiolabeled food iron availability in an in vitro digestion/Caco-2 cell culture model.
PubMed:Digestibility and peptide patterns of modified lysozyme after hydrolyzing by protease.
PubMed:Pancreatic dysfunction and treatment options.
PubMed:Postprandial cholecystokinin response in patients with chronic pancreatitis in treatment with oral substitutive pancreatic enzymes.
PubMed:An in vitro method, based on chewing, to predict resistant starch content in foods allows parallel determination of potentially available starch and dietary fiber.
PubMed:Fat gram target to achieve high energy intake in cystic fibrosis.
PubMed:Fine tuning a bile-enzymatic-gravimetric total dietary fiber method.
PubMed:Changes in activity, antigenicity, and molecular size of rice bran trypsin inhibitor by in vitro digestion.
PubMed:Identification of an antihypertensive peptide from casein hydrolysate produced by a proteinase from Lactobacillus helveticus CP790.
PubMed:In vitro mineral binding capacity of three fiber sources for Ca, Mg, Cu and Zn by two different methods.
PubMed:The nutritive value of stackburned yellow maize for livestock: tests in vitro and in broiler chicks.
PubMed:Effects of oven-drying tubers of two high-protein sweet potato varieties at different temperatures on their feeding value in broilers.
PubMed:Characterization of multiply phosphorylated peptides selectively precipitated from a pancreatic casein digest.
PubMed:Hydrolysis studies on oleamide in simulated gastrointestinal fluids.
PubMed:Advances in the treatment of cystic fibrosis.
PubMed:Stated versus actual lipase activity in pancreatic enzyme supplements: implications for clinical use.
PubMed:The precipitating factor in coeliac disease.
PubMed:Effect of stabilisation treatment of rice bran on nutritional quality of protein concentrates.
PubMed:No negative feedback regulation between plasma CCK levels and luminal tryptic activities in patients with pancreatic insufficiency.
PubMed:In vitro digestibility of proteins in black gram (Phaseolus mungo) and green gram (Phaseolus radiatus) papads.
PubMed:Modification of an in-vitro method for estimating the bioavailability of zinc and calcium from foods.
PubMed:[Sense and nonsense in the treatment of exocrine pancreatic insufficiency].
PubMed:Control of canine gastric emptying of fat by lipolytic products.
PubMed:The water-holding capacity of three starchy legumes in the raw, cooked and fibre-rich fraction forms.
PubMed:Generic and alternative brand-name pharmaceutical equivalents: select with caution.
PubMed:Enzyme treatment of exocrine pancreatic insufficiency in chronic pancreatitis.
PubMed:New methods for assessment of enzyme activity: do they help to optimize enzyme treatment?
PubMed:Short-chain fatty acid absorption in patients with cystic fibrosis.
PubMed:Effectiveness of enteric coated pancreatic enzymes given before meals in reducing steatorrhea in children with cystic fibrosis.
PubMed:[Comparison of some enzymatic methods for dietary fiber determination in foods].
PubMed:Pancreatic enzyme supplement dosage in cystic fibrosis.
PubMed:[Characteristics of peptide preparations obtained during enzymatic hydrolysis and ultrafiltration of milk proteins for use in specialized nutrition products].
PubMed:Effect of dietary proteins and/or their digestive products on intestinal taurocholate absorption.
PubMed:[An immunochemical analysis of enzymatic hydrolysates of milk and soy proteins intended for the production of specialized nutritional products].
PubMed:An analysis of contact lens enzyme cleaners.
PubMed:[Change in food proteins during technological processing].
PubMed:Proteolytic digestion of meat is not necessary for iron solubilization.
PubMed:Enzymic dephosphorylation of bovine casein to improve acid clotting properties and digestibility for infant formula.
PubMed:In vitro amino acid digestibility of food proteins as measured by the digestion cell technique.
PubMed:Human postprandial gastric emptying of 1-3-millimeter spheres.
PubMed:Characteristics of purified cows' milk xanthine oxidase and its submolecular characteristics.
PubMed:Solubility of inorganic iron as affected by proteolytic digestion.
PubMed:Chemical and nutritional assessment of sweetpotato proteins.
PubMed:Nutritional requirements in cystic fibrosis: a review.
PubMed:Effect of atropine on intestinal phase of pancreatic secretion in man.
PubMed:Declogging small-bore feeding tubes.
PubMed:Comparison of gastrointestinal pH in cystic fibrosis and healthy subjects.
PubMed:Digestion of polysaccharides of potato in the small intestine of man.
PubMed:[In vitro digestability of proteins in beans and peas prepared by various methods].
PubMed:Nutritional management of cystic fibrosis.
PubMed:An in vitro method for estimating biologically available vitamin B6 in processed foods.
PubMed:Food processing and the glycemic index.
PubMed:Trace element solubility from food following enzymolysis.
PubMed:Effect of protein treatment on the enzymatic hydrolysis of lysinoalanine and other amino acids.
PubMed:Effect of diet on exocrine pancreatic insufficiency in dogs.
PubMed:Gastric emptying and sieving of solid food and pancreatic and biliary secretion after solid meals in patients with truncal vagotomy and antrectomy.
PubMed:Evaluation of treatment for pancreatic exocrine insufficiency in dogs with ligated pancreatic ducts.
PubMed:An in vitro system for measuring intrinsic dietary mineral exchangeability: alternative to intrinsic isotopic labeling.
PubMed:Does mixing pancreatic enzyme microspheres (Pancrease) with food damage the enteric coating?
PubMed:An in vitro method for estimation of iron availability from meals.
PubMed:A new method of testing pancreatin therapy in vivo by the use of a peroral chymotrypsin substrate 4-(N-acetyl-L-tyrosyl)aminobenzoic acid.
PubMed:[Influence of hydrothermic and enzymatic treatments on the nutritive value of Faba beans: in vitro study].
PubMed:Determination of the total pepsin-pancreatin indigestible content (dietary fiber) of soybean products, wheat bran, and corn bran.
PubMed:Covalent attachment of amino acids to casein. 1. Chemical modification and rates of in vitro enzymatic hydrolysis of derivatives.
PubMed:Analysis of dietary fibre.
PubMed:Variation in in vitro digestibility of barley protein.
PubMed:In vitro digestibility of protein from barley and other cereals.
PubMed:The effect of the extent of hydrolysis in casein on its specific dynamic action in the rat.
PubMed:A method for improving the nutritional value of food proteins: covalent attachment of amino acids.
PubMed:[Ultra-flash sterilization of fluid food by friction].
PubMed:Nutritional and toxicological properties of some raw and modified starches.
PubMed:Bioavailability of food iron-(59Fe), vitamin B12-(60Co) and protein bound selenomethionine-(75Se) in pancreatic exocrine insufficiency due to cystic fibrosis.
PubMed:Absorption of inorganic iron- (59Fe2+) in relation to iron stores in pancreatic exocrine insufficiency due to cystic fibrosis.
PubMed:Quantitative determination of the content of available methionine and cysteine in food proteins.
PubMed:[Food protein quality. III Enzymatic ultrafiltrate digest (EUD) aminoacid index (author's transl)].
PubMed:[Diagnostic value of the vitamin A tolerance test in maldigestion and malabsorption (author's transl)].
PubMed:Reduction in mercury content of fish protein concentrate by enzymatic digestion.
PubMed:Measurement of digestibility of alfalfa protein concentrates by in vivo and in vitro methods.
PubMed:In vivo and in vitro methods of measuring nutritive value of leaf-protein preparations.
PubMed:A laboratory method for the evaluation of changes in protein quality.
PubMed:Analysis of enzymically digested food proteins by sephadex-gel filtration.
PubMed:A PEPSIN PANCREATIN DIGEST INDEX OF PROTEIN QUALITY EVALUATION.
 
Notes:
a mammalian pancreatic extract composed of enzymes with protease, amylase and lipase activities. it is used as a digestant in pancreatic malfunction. Isol. from pancreas of pig and cow. Digestive enzyme. Used in replacement therapy. Used to prepare protein hydrolysates for pre- and post-operative diets Pancreatin is a mixture of several digestive enzymes produced by the exocrine cells of the pancreas. It is composed of amylase, lipase and protease. This mixture is used to treat conditions in which pancreatic secretions are deficient, such as surgical pancreatectomy, pancreatitis and cystic fibrosis. It has been claimed to help with food allergies, celiac disease, autoimmune disease, cancer and weight loss. Pancreatin is sometimes called "pancreatic acid", although it is neither a single chemical substance nor an acid. A similar mixture of enzymes is sold as pancrelipase, which contains more active lipase enzyme than does pancreatin. (Wikipedia) Food additive and processing agent. Prod. by controlled fermentation of Aspergillus niger. Found in milk and milk products. Used in food processing for flavour improvement, e.g. in cheese Pancrelipase is a form of enzyme therapy for the treatment of various digestive disorders, primarily exocrine pancreatic insufficiency. It is a mixture of three digestive enzymes, amylase, trypsin, and lipase, which are normally produced by the pancreas. Pancrelipase is a form of pancreatin having a elevated content of lipase. (Wikipedia)
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