EU/US Properties Organoleptics Cosmetics Suppliers Safety Safety in use Safety references References Other Blenders Uses Occurrence Synonyms Articles Notes
 

N-hydroxysuccinimide
2,5-pyrrolidinedione, 1-hydroxy-

Supplier Sponsors

CAS Number: 6066-82-6Picture of molecule3D/inchi
ECHA EINECS - REACH Pre-Reg:228-001-3
FDA UNII: MJE3791M4T
Nikkaji Web:J26.034G
Beilstein Number:0113913
MDL:MFCD00005516
XlogP3:-1.40 (est)
Molecular Weight:115.08845000
Formula:C4 H5 N O3
BioActivity Summary:listing
NMR Predictor:Predict (works with chrome, Edge or firefox)
Category:cosmetic ingredient for skin conditioning
 
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Google Scholar:Search
Google Books:Search
Google Scholar: with word "volatile"Search
Google Scholar: with word "flavor"Search
Google Scholar: with word "odor"Search
Google Patents:Search
US Patents:Search
EU Patents:Search
Pubchem Patents:Search
PubMed:Search
NCBI:Search
 
Physical Properties:
Assay: 95.00 to 100.00
Food Chemicals Codex Listed: No
Boiling Point: 262.40 °C. @ 760.00 mm Hg (est)
Flash Point: 235.00 °F. TCC ( 112.50 °C. ) (est)
logP (o/w): -2.000 (est)
Soluble in:
 water, 1e+006 mg/L @ 25 °C (est)
 
Organoleptic Properties:
Odor and/or flavor descriptions from others (if found).
 
Cosmetic Information:
CosIng:cosmetic data
Cosmetic Uses: skin conditioning
 
Suppliers:
BOC Sciences
For experimental / research use only.
N-Hydroxysuccinimde 95%
EMD Millipore
For experimental / research use only.
N-Hydroxysuccinimide
Glentham Life Sciences
N-Hydroxysuccinimide
Santa Cruz Biotechnology
For experimental / research use only.
N-Hydroxysuccinimide ≥99%
Sigma-Aldrich: Aldrich
For experimental / research use only.
N-Hydroxysuccinimide 98%
TCI AMERICA
For experimental / research use only.
N-Hydroxysuccinimide >98.0%(T)
 
Safety Information:
Preferred SDS: View
 
Hazards identification
 
Classification of the substance or mixture
GHS Classification in accordance with 29 CFR 1910 (OSHA HCS)
None found.
GHS Label elements, including precautionary statements
 
Pictogram
 
Hazard statement(s)
None found.
Precautionary statement(s)
None found.
Oral/Parenteral Toxicity:
Not determined
Dermal Toxicity:
Not determined
Inhalation Toxicity:
Not determined
 
Safety in Use Information:
Category:
cosmetic ingredient for skin conditioning
Recommendation for N-hydroxysuccinimide usage levels up to:
 not for fragrance use.
 
Recommendation for N-hydroxysuccinimide flavor usage levels up to:
 not for flavor use.
 
Safety References:
EPI System: View
Chemical Carcinogenesis Research Information System:Search
AIDS Citations:Search
Cancer Citations:Search
Toxicology Citations:Search
EPA Substance Registry Services (TSCA):6066-82-6
EPA ACToR:Toxicology Data
EPA Substance Registry Services (SRS):Registry
Laboratory Chemical Safety Summary :80170
National Institute of Allergy and Infectious Diseases:Data
WGK Germany:3
1-hydroxypyrrolidine-2,5-dione
Chemidplus:0006066826
 
References:
 1-hydroxypyrrolidine-2,5-dione
NIST Chemistry WebBook:Search Inchi
Canada Domestic Sub. List:6066-82-6
Pubchem (cid):80170
Pubchem (sid):135037757
 
Other Information:
(IUPAC):Atomic Weights of the Elements 2011 (pdf)
Videos:The Periodic Table of Videos
tgsc:Atomic Weights use for this web site
(IUPAC):Periodic Table of the Elements
CHEMBL:View
HMDB (The Human Metabolome Database):Search
Export Tariff Code:2928.00.5000
ChemSpider:View
Wikipedia:View
 
Potential Blenders and core components note
None Found
 
Potential Uses:
None Found
 
Occurrence (nature, food, other):note
 not found in nature
 
Synonyms:
1-hydroxy-2,5-pyrrolidinedione
1-hydroxypyrrolidine-2,5-dione
1-hydroxysuccinimide
2,5-pyrrolidinedione, 1-hydroxy-
 succinimide, N-hydroxy- (8CI)
 

Articles:

PubMed:Synthesis, labeling and bioanalytical applications of a tris(2,2'-bipyridyl)ruthenium(II)-based electrochemiluminescence probe.
PubMed:Decoration of silk fibroin by click chemistry for biomedical application.
PubMed:Preparation and characterization of albumin conjugates of a truncated peptide YY analogue for half-life extension.
PubMed:Quantum dot loaded liposomes as fluorescent labels for immunoassay.
PubMed:Site-specific DOTA/europium-labeling of recombinant human relaxin-3 for receptor-ligand interaction studies.
PubMed:Photoabsorption and resonance energy transfer phenomenon in CdTe-protein bioconjugates: an insight into QD-biomolecular interactions.
PubMed:Development of an ionic liquid-based ultrasonic-assisted liquid-liquid microextraction method for sensitive determination of biogenic amines: application to the analysis of octopamine, tyramine and phenethylamine in beer samples.
PubMed:Conjugation behaviours of CdTe quantum dots and antibody by a novel immunochromatographic method.
PubMed:Fluorescent identification and detection of Staphylococcus aureus with carboxymethyl chitosan/CdS quantum dots bioconjugates.
PubMed:Bioconjugation of CdTe quantum dot for the detection of 2,4-dichlorophenoxyacetic acid by competitive fluoroimmunoassay based biosensor.
PubMed:Enzyme immunoassay for mycophenolic acid in milk and cheese.
PubMed:EDC/NHS-crosslinked type II collagen-chondroitin sulfate scaffold: characterization and in vitro evaluation.
PubMed:Detection of deoxynivalenol based on a single-chain fragment variable of the antideoxynivalenol antibody.
PubMed:Measurement of triclosan in water using a magnetic particle enzyme immunoassay.
PubMed:Regulatory effect of amino acids on the pasting behavior of potato starch is attributable to its binding to the starch chain.
PubMed:Survival of baboon biotin-X-N-hydroxysuccinimide and (111)In-oxine-labelled autologous fresh and lyophilized reconstituted platelets.
PubMed:Development of antibodies for the detection of N-acetyl-glufosinate.
PubMed:Development of an enzyme-linked immunosorbent assay for the detection of the organophosphorus insecticide acephate.
PubMed:Purification of TAXI-like endoxylanase inhibitors from wheat (Triticum aestivum L.) whole meal reveals a family of iso-forms.
PubMed:Development of an immunoassay for the residues of the herbicide bensulfuron-methyl.
PubMed:Preparation of specific antisera to 15alpha-hydroxyestrogens.
 
Notes:
None found
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