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Category:pharmaceuticals / chemical synthisis
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to pale yellow clear liquid (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.67500 @ 25.00 °C.
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| Refractive Index: | 1.37200 @ 20.00 °C.
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| Melting Point: | -140.00 °C. @ 760.00 mm Hg (est)
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| Boiling Point: | 36.50 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 495.356995 mmHg @ 25.00 °C. (est) |
| Flash Point: | -33.00 °F. TCC ( -36.11 °C. )
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| logP (o/w): | 0.700 |
| Soluble in: |
| | water, 3.451e+005 mg/L @ 25 °C (est) |
Organoleptic Properties:
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | pharmaceuticals / chemical synthisis |
| Recommendation for N,N-dimethyl ethyl amine usage levels up to: | | | not for fragrance use.
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| Recommendation for N,N-dimethyl ethyl amine flavor usage levels up to: |
| | not for flavor use.
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Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | amines, C13-15-alkyldimethyl | | N,N- | dimethylethanamine | | | dimethylethylamine | | N,N- | dimethylethylamine | | | DMEA | | | ethanamine, N,N-dimethyl- | | | ethylamine, dimethyl- | | | ethylamine, N,N-dimethyl- | | | ethyldimethylamine | | N- | ethyldimethylamine | | | methanamine, N-ethyl-N-methyl- |
Articles:
| PubMed:Desmodeleganine, a new alkaloid from the leaves of Desmodium elegans as a potential monoamine oxidase inhibitor. |
| PubMed:Studies on the nuances of the electrochemically induced room temperature isomerization of cis-stilbene in acetonitrile and ionic liquids. |
| PubMed:Self-reinforced endocytoses of smart polypeptide nanogels for "on-demand" drug delivery. |
| PubMed:Human trace amine-associated receptor TAAR5 can be activated by trimethylamine. |
| PubMed:Cytotoxicity study of novel water-soluble chitosan derivatives applied as membrane material of alginate microcapsules. |
| PubMed:Use of recreational drug 1,3 Dimethylamylamine (DMAA) [corrected] associated with cerebral hemorrhage. |
| PubMed:Ammonia as a preferred additive in chiral and achiral applications of supercritical fluid chromatography for small, drug-like molecules. |
| PubMed:Synthesis and Properties of Dissymmetric Gemini Surfactants. |
| PubMed:Thermochemistry of Alane Complexes for Hydrogen Storage: A Theoretical and Experimental Investigation. |
| PubMed:Formation and properties of stabilized aluminum nanoparticles. |
| PubMed:Inorganic or organic azide-containing hypergolic ionic liquids. |
| PubMed:Photoreduction of oxoisoaporphines by amines: laser flash and steady-state photolysis, pulse radiolysis, and TD-DFT studies. |
| PubMed:New universal, portable and cryogenic sampler for time weighted average monitoring of H2S, NH3, benzene, toluene, ethylbenzene, xylenes and dimethylethylamine. |
| PubMed:1,2-Eliminations from (CH3)2NH+CH2CH3 and (CH3)2NH2+: guided dissociations. |
| PubMed:Aluminum-coated hollow glass fibers for ArF-excimer laser light fabricated by metallorganic chemical-vapor deposition. |
| PubMed:Physicochemical properties of tamoxifen hemicitrate sesquihydrate. |
| PubMed:Physicochemical characterization of tamoxifen citrate pseudopolymorphs, methanolate and ethanolate. |
| PubMed:Regenerating fuel-gas desulfurizing agents by using bipolar membrane electrodialysis (BMED): effect of molecular structure of alkanolamines on the regeneration performance. |
| PubMed:Analgesic and anti-inflammatory activities evaluation of (-)-O-acetyl, (-)-O-methyl, (-)-O-dimethylethylamine cubebin and their preparation from (-)-cubebin. |
| PubMed:Enzyme-mediated precipitation of parent drugs from their phosphate prodrugs. |
| PubMed:[Synthesis of new N3S pseudo-peptide complexes and biodistribution in mice]. |
| PubMed:Oleiphilaceae fam. nov., to include Oleiphilus messinensis gen. nov., sp. nov., a novel marine bacterium that obligately utilizes hydrocarbons. |
| PubMed:Exposure to chemical agents in Swedish aluminum foundries and aluminum remelting plants--a comprehensive survey. |
| PubMed:Cholesterol biosynthesis from lanosterol: molecular cloning, chromosomal localization, functional expression and liver-specific gene regulation of rat sterol delta8-isomerase, a cholesterogenic enzyme with multiple functions. |
| PubMed:Delivery of F2-excimer laser light by aluminum hollow fibers. |
| PubMed:Carboxylic acid analogues of tamoxifen: (Z)-2-[p-(1, 2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine. Estrogen receptor affinity and estrogen antagonist effects in MCF-7 cells. |
| PubMed:[Steady state and disappearance of the metabolites of miproxifene phosphate in the treatment of breast cancer]. |
| PubMed:[Phase I study of TAT-59 (a new antiestrogen) in breast cancer. TAT-59 Study Group]. |
| PubMed:Effects of OK-432 (picibanil) on the estrogen receptors of MCF-7 cells and potentiation of antiproliferative effects of tamoxifen in combination with OK-432. |
| PubMed:Skin absorption of the industrial catalyst dimethylethylamine in vitro in guinea pig and human skin, and of gaseous dimethylethylamine in human volunteers. |
| PubMed:Antiestrogenic activity of DP-TAT-59, an active metabolite of TAT-59 against human breast cancer. |
| PubMed:Acute toxicity and primary irritancy of alkylalkanolamines. |
| PubMed:Effect of dietary intake of trimethylamine on human metabolism of the industrial catalyst dimethylethylamine. |
| PubMed:Phosphatidylethanolamine and sarcolemmal damage during ischemia or metabolic inhibition of heart myocytes. |
| PubMed:A new triphenylethylene derivative, TAT-59; hormone receptors; insulin-like growth factor 1; and growth suppression of hormone-dependent MCF-7 tumors in athymic mice. |
| PubMed:Gas chromatographic determination of primary and secondary low-molecular-mass aliphatic amines in urine using derivatization with isobutyl chloroformate. |
| PubMed:Interaction of tricyclic drug analogs with synaptic plasma membranes: structure-mechanism relationships in inhibition of neuronal Na+/K(+)-ATPase activity. |
| PubMed:Interaction of DP-TAT-59, an active metabolite of new triphenylethylene-derivative (TAT-59), with estrogen receptors. |
| PubMed:Carcinogenesis and mutagenesis by N-nitroso compounds having a basic center. |
| PubMed:Liquid membrane work-up of blood plasma samples applied to gas chromatographic determination of aliphatic amines. |
| PubMed:Local and systemic carcinogenic effects of alkylating carcinogens in rats treated by intravesicular administration. |
| PubMed:Dimethylethylamine in mould core manufacturing: exposure, metabolism, and biological monitoring. |
| PubMed:Visual disturbances in man as a result of experimental and occupational exposure to dimethylethylamine. |
| PubMed:Experimental study on the metabolism of dimethylethylamine in man. |
| PubMed:Effects of estrogen on cell proliferation and leukotriene formation in transformed mouse Leydig cells cultured under serum-free conditions. |
| PubMed:NTP Toxicology and Carcinogenesis Studies of Diphenhydramine Hydrochloride (CAS No. 147-24-0) in F344/N Rats and B6C3F1 Mice (Feed Studies). |
| PubMed:An industrial hygiene appraisal of triethylamine and dimethylethylamine exposure limits in the foundry industry. |
| PubMed:Occupational exposure to volatile nitrosamines in foundries using the "Ashland" core-making process. |
| PubMed:Simultaneous determination of tamoxifen citrate and its E isomer impurity in bulk drug and tablets by high-performance liquid chromatography. |
| PubMed:Isotachophoretic determination of amines from workroom air. |
| PubMed:Placental transfer of diphenhydramine in chronically instrumented pregnant sheep. |
| PubMed:[Pharmacokinetics and bioavailability of diphenhydramine in man]. |
| PubMed:Determination of dimethylethylamine in air samples from iron foundries by isotachophoresis. |
| PubMed:Respiratory disease in foundry workers. |
| PubMed:Estrogenic and antiestrogenic activity of monophenolic analogues of tamoxifen, (Z)-2-[p-(1,2-diphenyl-1-butenyl)phenoxy]-N, N-dimethylethylamine. |
| PubMed:[Scope and limitations of the analytical use of dansyl chloride, I: The reaction of aromatic sulfonyl chlorides with aliphatic tertiary amines: the microanalytical aspects of the Hinsberg test (author's transl)]. |
| PubMed:The control of pharmaceuticals. IX. The nuclear magnetic resonance spectra of substituted 2-(di-phenylmethoxy)-N-N-dimethylethylamine hydrochlorides or maleates. |
| PubMed:The infrared spectra of substituted 2-(diphenylmethoxy)-N,N-dimethylethylamine hydrochlorides. |
| PubMed:The influence of xyloxemine hydrochloride, 2-[2-(DI-2,6-xylylmethoxy)ethoxy]-N,N-dimethylethylamine hydrochloride, on reproduction in laboratory animals. |
| PubMed:Investigation of xyloxemine hydrochloride, 2-[2-(di-2,6-xylylmethoxy)ethoxy]-N,N-dimethylethylamine hydrochloride (BS 6748). |
| PubMed:Pharmacological properties of xyloxemine hydrochloride, 2-[2-(di-2,6-xylylmethoxy) ethoxy]-N,N-dimethylethylamine hydrochloride (BS 6748), a new antitussive agent. |
| PubMed:Toxicological data of 2-[2-(DI-2,6-xylylmethoxy) ethoxy]-N,N-dimethylethylamine hydrochloride (BS 6748). |
| PubMed:[Determination of 8-chlorotheophylline-2-(benzohydryloxy)-N-N-dimethylethylamine]. |
| PubMed:[Study of the use of dimenhydrinate (2-(benzylhydroxy)-N, N-dimethylethylamine 8-chlorotheophyllinate) in vomiting and nausea in pregnancy]. |
| PubMed:[Potentiometric determination of the hydrochlorides of 2,2'-dichloro-N-methyldiethylamine (DEMA), of 2,2', 2"-trichlorotriethylamine, and of 2-chloro-N,N-dimethylethylamine]. |
| PubMed:[Experience in 58 cases of bronchial asthma treated with 2-(benzohydryloxy)-N,N-dimethylethylamine 8-chlorotheophyllinate; preliminary report]. |
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3D/inchi