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 Category:information only not used for fragrances or flavors 
  
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information: 
  
Physical Properties: 
| Appearance: | colorless to pale yellow clear liquid (est) |  
| Assay: |  95.00 to 100.00 
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| Food Chemicals Codex Listed:  | No |  
| Melting Point: |   33.00 °C. @  760.00 mm Hg
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| Boiling Point: |  183.50 °C. @  760.00 mm Hg
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| Vapor Pressure: | 0.380000 mmHg @  25.00 °C. |  
| Flash Point: |  185.00 °F. TCC (   85.00 °C. )
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| logP (o/w): |  -0.655 (est) |  
| Soluble in: |  
|   | alcohol |  |   | water, 1.00E+06 mg/L @ 20 °C (exp) |  
 
  
Organoleptic Properties: 
| Odor and/or flavor descriptions from others (if found). |  
 
  
Cosmetic Information: 
  
Suppliers: 
  
Safety Information: 
| Preferred SDS: View |  
|   |  
| Hazards identification |  
|   |  
|  Classification of the substance or mixture |  
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |  
| None found. |  
|  GHS Label elements, including precautionary statements |  
|   |  
| Pictogram |  |  
|   |  
                                                                     
| Hazard statement(s) |  
| None found. |  
| Precautionary statement(s) |  
| None found. |  
| Oral/Parenteral Toxicity:  |  
| 
Not determined
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| Dermal Toxicity:  |  
| 
Not determined
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| Inhalation Toxicity:  |  
| 
Not determined
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Safety in Use Information: 
| Category:  |  | information only not used for fragrances or flavors |  
| Recommendation for meso-2,3-butane diol usage levels up to:  |  |   | not for fragrance use.
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|   |  
| Recommendation for meso-2,3-butane diol flavor usage levels up to:  |  
|   | not for flavor use.
 |  
 
  
Safety References: 
  
References: 
  
Other Information: 
  
Potential Blenders and core components  note 
  
Potential Uses: 
  
Occurrence (nature, food, other): note 
  
Synonyms: 
| (2R,3S)- | butane-2,3-diol |  | (2R,3S)-rel-2,3- | butanediol |  | meso-2,3- | butanediol |  | 2,3- | butanediol (meso) |  | 2,3- | butanediol, (2R,3S)- |  | 2,3- | butanediol, (R*, S*)- |  | 2,3- | butanediol, meso- |  |   | erythro-2,3-butane diol |  
 
  
Articles:
| PubMed:2-Butanol and Butanone Production in Saccharomyces cerevisiae through Combination of a B12 Dependent Dehydratase and a Secondary Alcohol Dehydrogenase Using a TEV-Based Expression System. |  
| PubMed:Cloning, expression and characterization of glycerol dehydrogenase involved in 2,3-butanediol formation in Serratia marcescens H30. |  
| PubMed:Genome Sequence of meso-2,3-Butanediol-Producing Strain Serratia marcescens ATCC 14041. |  
| PubMed:Mechanism of 2,3-butanediol stereoisomer formation in Klebsiella pneumoniae. |  
| PubMed:Deletion of meso-2,3-butanediol dehydrogenase gene budC for enhanced D-2,3-butanediol production in Bacillus licheniformis. |  
| PubMed:Glycerol dehydrogenase plays a dual role in glycerol metabolism and 2,3-butanediol formation in Klebsiella pneumoniae. |  
| PubMed:Efficient bioconversion of 2,3-butanediol into acetoin using Gluconobacter oxydans DSM 2003. |  
| PubMed:Synthesis of 2,3-butanediol by Synechocystis sp. PCC6803 via heterologous expression of a catabolic pathway from lactic acid- and enterobacteria. |  
| PubMed:Improved cellobiose utilization in E. coli by including both hydrolysis and phosphorolysis mechanisms. |  
| PubMed:A newly isolated Bacillus licheniformis strain thermophilically produces 2,3-butanediol, a platform and fuel bio-chemical. |  
| PubMed:Enantiomeric recognition of amino acid salts by macrocyclic crown ethers derived from enantiomerically pure 1,8,9,16-tetrahydroxytetraphenylenes. |  
| PubMed:A new NAD(H)-dependent meso-2,3-butanediol dehydrogenase from an industrially potential strain Serratia marcescens H30. |  
| PubMed:High-yield production of meso-2,3-butanediol from cellodextrin by engineered E. coli biocatalysts. |  
| PubMed:Cloning, expression and characterization of meso-2,3-butanediol dehydrogenase from Klebsiella pneumoniae. |  
| PubMed:Synthesis of pure meso-2,3-butanediol from crude glycerol using an engineered metabolic pathway in Escherichia coli. |  
| PubMed:Aromatic compounds from the halotolerant fungal strain of Wallemia sebi PXP-89 in a hypersaline medium. |  
| PubMed:Characterization of a zinc-containing alcohol dehydrogenase with stereoselectivity from the hyperthermophilic archaeon Thermococcus guaymasensis. |  
| PubMed:D-2,3-butanediol production due to heterologous expression of an acetoin reductase in Clostridium acetobutylicum. |  
| PubMed:Relationship between changes in the total concentration of acetic acid bacteria and major volatile compounds during the acetic acid fermentation of white wine. |  
| PubMed:Microbial production of meso-2,3-butanediol by metabolically engineered Escherichia coli under low oxygen condition. |  
| PubMed:Metabolic engineering of acetoin and meso-2, 3-butanediol biosynthesis in E. coli. |  
| PubMed:Effects of straight chain alcohols on specific isoforms of adenylyl cyclase. |  
| PubMed:Role of Saccharomyces cerevisiae oxidoreductases Bdh1p and Ara1p in the metabolism of acetoin and 2,3-butanediol. |  
| PubMed:From simple diols to carbohydrate derivatives of phenylarsonic acid. |  
| PubMed:Determination of 2,3-butanediol and 2-hydroxybutanone stereoisomers in batteries of traditional balsamic vinegar. |  
| PubMed:Fermentation product butane 2,3-diol induces Ca2+ transients in E. coli through activation of lanthanum-sensitive Ca2+ channels. |  
| PubMed:Male-specific EAD active compounds produced by female European chafer Rhizotrogus majalis (Razoumowsky). |  
| PubMed:Chiral direction and interconnection of helical three-connected networks in metal-organic frameworks. |  
| PubMed:Ab initio conformational studies on diols and binary diol-water systems using DFT methods. Intramolecular hydrogen bonding and 1:1 complex formation with water. |  
| PubMed:Crystallization and preliminary X-ray studies of meso-2,3-butanediol dehydrogenase from Klebsiella pneumoniae IAM1063. |  
| PubMed:Crystal structure of meso-2,3-butanediol dehydrogenase in a complex with NAD+ and inhibitor mercaptoethanol at 1.7 A resolution for understanding of chiral substrate recognition mechanisms. |  
| PubMed:Structural analysis of diols by electrospray mass spectrometry on boric acid complexes. |  
| PubMed:Production of 2,3-butanediol by newly isolated Enterobacter cloacae. |  
| PubMed:Separation of racemic from meso-2,3-butanediol |  
| PubMed:Formation of a chiral acetoinic compound from diacetyl by Escherichia coli expressing meso-2,3-butanediol dehydrogenase. |  
| PubMed:The production of D-acetoin by a transgenic Escherichia coli. |  
| PubMed:An electron paramagnetic resonance study on the mechanism-based inactivation of adenosylcobalamin-dependent diol dehydrase by glycerol and other substrates. |  
| PubMed:Metabolism of 2,3-butanediol stereoisomers in the perfused rat liver. |  
| PubMed:Enantio- and regioselectivity in the epoxide-hydrolase-catalyzed ring opening of aliphatic oxiranes: Part II: Dialkyl- and trialkylsubstituted oxiranes. |  
| PubMed:Properties of 2,3-Butanediol Dehydrogenases from Lactococcus lactis subsp. lactis in Relation to Citrate Fermentation. |  
| PubMed:Assay of physiological levels of 2,3-butanediol diastereomers in blood and urine by gas chromatography-mass spectrometry. |  
| PubMed:Short chain diol metabolism in human disease states. |  
| PubMed:The measurement of 1,2-propanediol, D, L-2,3-butanediol and meso-2,3-butanediol in controls and alcoholic cirrhotics. |  
| PubMed:Electron-capture, capillary column gas chromatographic determination of low-molecular-weight diols in serum. |  
| PubMed:Production of 2-butanol through meso-2,3-butanediol consumption in lactic acid bacteria. |  
 
  
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