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Category:dietary supplements
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | white to aple yellow powder (est) |
| Assay: | 89.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Soluble in: |
| | water |
Organoleptic Properties:
| Odor Strength:none |
| Odor Description:at 100.00 %. odorless |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
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| Hazards identification |
| |
| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
| |
| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
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Not determined
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| Dermal Toxicity: |
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Not determined
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| Inhalation Toxicity: |
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Not determined
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Safety in Use Information:
| Category: | | dietary supplements |
| Recommendation for calcium ascorbate dihydrate usage levels up to: | | | not for fragrance use.
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| Recommendation for calcium ascorbate dihydrate flavor usage levels up to: |
| | not for flavor use.
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Safety References:
European Food Safety Authority (EFSA) reference(s):
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um ascorbate, magnesium ascorbate and zinc ascorbate added for nutritional purposes in food supplements
View page or View pdf
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Opinion of the Scientific Panel on food additives, flavourings, processing aids and materials in contact with food (AFC) related to Calcium ascorbate with a content of threonate for use as a source of vitamin C in food supplements
View page or View pdf
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Scientific Opinion on the safety and efficacy of vitamin C (ascorbic acid, sodium ascorbate, calcium ascorbate, ascorbyl palmitate, sodium calcium ascorbyl phosphate and sodium ascorbyl phosphate) as a feed additive for all animal species based on a dossier submitted by DSM Nutritional Products Ltd
View page or View pdf
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Scientific Opinion on the re-evaluation of ascorbic acid (E 300), sodium ascorbate (E 301) and calcium ascorbate (E 302) as food additives
View page or View pdf
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| AIDS Citations:Search |
| Cancer Citations:Search |
| Toxicology Citations:Search |
| EPA ACToR:Toxicology Data |
| EPA Substance Registry Services (SRS):Registry |
| Laboratory Chemical Safety Summary :54713436 |
| National Institute of Allergy and Infectious Diseases:Data |
| WGK Germany:1 |
| calcium 5-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-4-oxofuran-2-olate hydrate |
| Chemidplus:0005743282 |
References:
| | calcium 5-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-4-oxofuran-2-olate hydrate |
| NIST Chemistry WebBook: | Search Inchi |
| Pubchem (cid): | 54713436 |
| Pubchem (sid): | 135253515 |
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| | acetic acid calcium salt dihydrate | | L- | ascorbic acid calcium salt dihydrate | | laevo- | ascorbic acid calcium salt dihydrate | | | calcium 5-[(1S)-1,2-dihydroxyethyl]-3-hydroxy-4-oxofuran-2-olate hydrate | | | calcium L-ascorbate dihydrate | | | calcium laevo-ascorbate dihydrate |
Articles:
| PubMed:Effects of hot boning and moisture enhancement on the eating quality of cull cow beef. |
| PubMed:Combined effects of potassium lactate and calcium ascorbate as sodium chloride substitutes on the physicochemical and sensory characteristics of low-sodium frankfurter sausage. |
| PubMed:Reduction of sodium and increment of calcium and ω-3 polyunsaturated fatty acids in dry fermented sausages: effects on the mineral content, lipid profile and sensory quality. |
| PubMed:Effects of 1-methylcyclopropene and post-controlled atmosphere air storage treatments on fresh-cut Ambrosia apple slices. |
| PubMed:The effects of skeletal separation and moisture enhancement for improving the eating quality of cull cow beef. |
| PubMed:Vitamin A and C compounds permitted in supplements differ in their abilities to affect cell viability, DNA and the DNA nucleoside deoxyguanosine. |
| PubMed:Surface treatments and coatings to maintain fresh-cut mango quality in storage. |
| PubMed:Antibrowning and antimicrobial properties of sodium acid sulfate in apple slices. |
| PubMed:Vitamin C with metabolites: additional analysis suggests favorable changes in oxalate. |
| PubMed:Vitamin C with metabolites reduce oxalate levels compared to ascorbic acid: a preliminary and novel clinical urologic finding. |
| PubMed:Effect of tenderizers combined with organic acids on Escherichia coli O157:H7 thermal resistance in non-intact beef. |
| PubMed:Noninvasive in situ identification and band assignments of some pharmaceutical excipients inside USP vials with FT-near-infrared spectroscopy. |
| PubMed:Vitamin C-lipid metabolites: uptake and retention and effect on plasma C-reactive protein and oxidized LDL levels in healthy volunteers. |
| PubMed:Vitamin C metabolites, independent of smoking status, significantly enhance leukocyte, but not plasma ascorbate concentrations. |
| PubMed:Thermal inactivation of Escherichia coli O157:H7 in beef treated with marination and tenderization ingredients. |
| PubMed:Moisturizing potentials of ascorbyl palmitate and calcium ascorbate in various topical formulations. |
| PubMed:Effect of ionizing radiation on furan formation in fresh-cut fruits and vegetables. |
| PubMed:Control of browning and microbial growth on fresh-cut apples by sequential treatment of sanitizers and calcium ascorbate. |
| PubMed:Absorption rates and free radical scavenging values of vitamin C-lipid metabolites in human lymphoblastic cells. |
| PubMed:Comparing the moisturizing effects of ascorbic acid and calcium ascorbate against that of tocopherol in emulsions. |
| PubMed:Safety and tolerance of ester-C compared with regular ascorbic acid. |
| PubMed:Final report of the safety assessment of L-Ascorbic Acid, Calcium Ascorbate, Magnesium Ascorbate, Magnesium Ascorbyl Phosphate, Sodium Ascorbate, and Sodium Ascorbyl Phosphate as used in cosmetics. |
| PubMed:Effect of pH on the survival of Listeria innocua in calcium ascorbate solutions and on quality of fresh-cut apples. |
| PubMed:Calcium bioavailability and kinetics of calcium ascorbate and calcium acetate in rats. |
| PubMed:[Reduced pain from osteoarthritis in hip joint or knee joint during treatment with calcium ascorbate. A randomized, placebo-controlled cross-over trial in general practice]. |
| PubMed:Effects of calcium salts on beef longissimus quality. |
| PubMed:Effects of processing treatment and sorbate addition on the flavor characteristics of apple cider. |
| PubMed:Preventing the common cold with a vitamin C supplement: a double-blind, placebo-controlled survey. |
| PubMed:Calcium ascorbate as a potential partial substitute for NaCl in dry fermented sausages: effect on colour, texture and hygienic quality at different concentrations. |
| PubMed:Enhanced production of mineralized nodules and collagenous proteins in vitro by calcium ascorbate supplemented with vitamin C metabolites. |
| PubMed:Intestinal absorption of calcium from calcium ascorbate in rats. |
| PubMed:Absorption of calcium oxalate does not require dissociation in rats. |
| PubMed:Comparison of the anti-scorbutic activity of L-ascorbic acid and Ester C in the non-ascorbate synthesizing Osteogenic Disorder Shionogi (ODS) rat. |
| PubMed:Effect of ascorbate and dehydroascorbate on tissue uptake of glucose. |
| PubMed:An acute study on the relative gastro-intestinal absorption of a novel form of calcium ascorbate. |
| PubMed:Neutrophil mobility during anaesthesia in children. A trial of ascorbate premedication. |
| PubMed:Is calcium ascorbate preferable to sodium ascorbate? |
| PubMed:Characteristics of the response of dispersed guinea-pig adrenal cells to low doses (1-50 pg/ml) of alpha 1-24 adrenocorticotrophin. |
| PubMed:An in vitro assessment of cellular and humoral immune function in pulmonary tuberculosis: correction of defective neutrophil motility by ascorbate, levamisole, metoprolol and propranolol. |
| PubMed:The influence of hormones and other substances on lens regeneration in vitro. |
| PubMed:Effects of ascorbate on leucocytes: Part III. In vitro and in vivo stimulation of abnormal neutrophil motility by ascorbate. |
| PubMed:Effects of ascorbate on leucocytes: Part I. Effects of ascorbate on neutrophil motility and intracellular cyclic nucleotide levels in vitro. |
| PubMed:Ascorbate inhibition of 6-aminonicotinamide teratogenesis in chicken embryos. |
| PubMed:Winter illness and vitamin C: the effect of relatively low doses. |
| PubMed:[Clinical experience in the use of calcium ascorbate in otorhinolaryngology]. |
| PubMed:The effect of calcium ascorbate on the resorption of blood clots following injury to the skull in experimental animals. |
| PubMed:[The effect of calcium ascorbate on therapeutic process in fracture healing; experimental research]. |
| PubMed:Calcium ascorbate in otolaryngology. |
| PubMed:[Calcium and vitamin C in pulmonary tuberculosis; experiences with a new salt, calcium ascorbate]. |
| PubMed:[Effect of the Soviet preparation of calcium ascorbate of the permeability and vitamin C metabolism]. |
| PubMed:The influence of ascorbic acid, sodium ascorbate, calcium ascorbate and orange juice on dental enamel. |
| PubMed:Crystalline Dihydrate of Calcium Ascorbate. |
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3D/inchi