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Category:flavoring agents
US / EU / FDA / JECFA / FEMA / FLAVIS / Scholar / Patent Information:
Physical Properties:
| Appearance: | colorless to yellow clear liquid (est) |
| Assay: | 95.00 to 100.00
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| Food Chemicals Codex Listed: | No |
| Specific Gravity: | 0.68700 to 0.69300 @ 25.00 °C.
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| Pounds per Gallon - (est).: | 5.717 to 5.766
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| Refractive Index: | 1.36700 to 1.37300 @ 20.00 °C.
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| Melting Point: | -101.00 to -99.00 °C. @ 760.00 mm Hg
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| Boiling Point: | 32.00 to 34.00 °C. @ 760.00 mm Hg
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| Vapor Pressure: | 607.728027 mmHg @ 25.00 °C. (est) |
| Vapor Density: | 2.04 ( Air = 1 ) |
| Flash Point: | -26.00 °F. TCC ( -32.22 °C. )
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| logP (o/w): | 0.260 |
| Soluble in: |
| | alcohol | | | water, 8.381e+005 mg/L @ 25 °C (est) | | | water, 1.00E+06 mg/L @ 25 °C (exp) |
Organoleptic Properties:
| Odor Type: fishy |
| fishy ammoniacal |
| Odor Description:at 0.10 % in propylene glycol. fishy ammoniacal |
| Odor and/or flavor descriptions from others (if found). |
Cosmetic Information:
Suppliers:
Safety Information:
| Preferred SDS: View |
| European information : |
| Most important hazard(s): | | Xn - Harmful. |
R 12 - Extremely flammable.
R 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
R 34 - Causes burns.
S 02 - Keep out of the reach of children.
S 16 - Keep away from sources of ignition - No Smoking.
S 26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S 36/37/39 - Wear suitable clothing, gloves and eye/face protection.
S 45 - In case of accident or if you feel unwell seek medical advice immediately.
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| Hazards identification |
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| Classification of the substance or mixture |
| GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) |
| None found. |
| GHS Label elements, including precautionary statements |
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| Pictogram | |
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| Hazard statement(s) |
| None found. |
| Precautionary statement(s) |
| None found. |
| Oral/Parenteral Toxicity: |
oral-rat LD50 111 mg/kg
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
LUNGS, THORAX, OR RESPIRATION: DYSPNEA
GASTROINTESTINAL: OTHER CHANGES
National Technical Information Service. Vol. OTS0542011
oral-guinea pig LD50 2700 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(3), Pg. 79, 1980.
oral-mouse LD50 2200 mg/kg
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(3), Pg. 79, 1980.
oral-rabbit LD50 3200 mg/kg
SKIN AND APPENDAGES (SKIN): HAIR: OTHER
GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA"
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(3), Pg. 79, 1980.
unreported-mammal (species unspecified) LD50 500 mg/kg
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 80, 1975.
intraperitoneal-rat LDLo 50 mg/kg
Farmakologiya i Toksikologiya Vol. 31, Pg. 238, 1968.
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| Dermal Toxicity: |
skin-rabbit LD50 380 mg/kg
Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974
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| Inhalation Toxicity: |
inhalation-rat LC50 4000 ppm/4H
Interagency Collaborative Group on Environmental Carcinogenesis, National Cancer Institute, Memorandum, June 17, 1974Vol. 17JUN1974
inhalation-mammal (species unspecified) LC50 1800 mg/m3
Toksikologiya Novykh Promyshlennykh Khimicheskikh Veshchestv. Toxicology of New Industrial Chemical Substances. For English translation, see TNICS*. Vol. 14, Pg. 80, 1975.
inhalation-mouse LCLo 7000 ppm/40M
Shell Chemical Company. Unpublished Report. Vol. -, Pg. 7, 1961.
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Safety in Use Information:
| Category: | | flavoring agents |
| Recommendation for isopropyl amine usage levels up to: | | | not for fragrance use.
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| Maximised Survey-derived Daily Intakes (MSDI-EU): | 0.012 (μg/capita/day) |
| Maximised Survey-derived Daily Intakes (MSDI-USA): | 0.02 (μg/capita/day) |
| Modified Theoretical Added Maximum Daily Intake (mTAMDI): | 340 (μg/person/day) |
| Threshold of Concern: | 1800 (μg/person/day) |
| Structure Class: | I |
| Use levels for FEMA GRAS flavoring substances on which the FEMA Expert Panel based its judgments that the substances are generally recognized as safe (GRAS). |
| The Expert Panel also publishes separate extensive reviews of scientific information on all FEMA GRAS flavoring substances and can be found at FEMA Flavor Ingredient Library |
| publication number: 22 |
| Click here to view publication 22 |
| | average usual ppm | average maximum ppm |
| baked goods: | 2.00000 | 10.00000 |
| beverages(nonalcoholic): | - | - |
| beverages(alcoholic): | - | - |
| breakfast cereal: | 0.20000 | 1.00000 |
| cheese: | 0.40000 | 2.00000 |
| chewing gum: | - | - |
| condiments / relishes: | 0.10000 | 0.50000 |
| confectionery froastings: | 1.00000 | 5.00000 |
| egg products: | - | - |
| fats / oils: | 0.10000 | 0.50000 |
| fish products: | 0.20000 | 1.00000 |
| frozen dairy: | 0.40000 | 2.00000 |
| fruit ices: | 0.40000 | 2.00000 |
| gelatins / puddings: | - | - |
| granulated sugar: | - | - |
| gravies: | 0.10000 | 0.50000 |
| hard candy: | - | - |
| imitation dairy: | - | - |
| instant coffee / tea: | - | - |
| jams / jellies: | - | - |
| meat products: | 0.20000 | 1.00000 |
| milk products: | 0.40000 | 2.00000 |
| nut products: | - | - |
| other grains: | 0.20000 | 1.00000 |
| poultry: | 0.20000 | 1.00000 |
| processed fruits: | 0.40000 | 2.00000 |
| processed vegetables: | - | - |
| reconstituted vegetables: | - | - |
| seasonings / flavors: | 0.10000 | 0.50000 |
| snack foods: | 1.00000 | 5.00000 |
| soft candy: | - | - |
| soups: | 0.10000 | 0.50000 |
| sugar substitutes: | - | - |
| sweet sauces: | - | - |
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| Food categories according to Commission Regulation EC No. 1565/2000 (EC, 2000) in FGE.06 (EFSA, 2002a). According to the Industry the "normal" use is defined as the average of reported usages and "maximum use" is defined as the 95th percentile of reported usages (EFSA, 2002i). |
| Note: mg/kg = 0.001/1000 = 0.000001 = 1/1000000 = ppm. |
| | average usage mg/kg | maximum usage mg/kg |
| Dairy products, excluding products of category 02.0 (01.0): | 0.40000 | 2.00000 |
| Fats and oils, and fat emulsions (type water-in-oil) (02.0): | 0.10000 | 0.50000 |
| Edible ices, including sherbet and sorbet (03.0): | 0.40000 | 2.00000 |
| Processed fruit (04.1): | 0.40000 | 2.00000 |
| Processed vegetables (incl. mushrooms & fungi, roots & tubers, pulses and legumes), and nuts & seeds (04.2): | - | - |
| Confectionery (05.0): | 1.00000 | 5.00000 |
| Chewing gum (05.3): | - | - |
| Cereals and cereal products, incl. flours & starches from roots & tubers, pulses & legumes, excluding bakery (06.0): | 0.20000 | 1.00000 |
| Bakery wares (07.0): | 2.00000 | 10.00000 |
| Meat and meat products, including poultry and game (08.0): | 0.20000 | 1.00000 |
| Fish and fish products, including molluscs, crustaceans and echinoderms (MCE) (09.0): | 0.20000 | 1.00000 |
| Eggs and egg products (10.0): | - | - |
| Sweeteners, including honey (11.0): | - | - |
| Salts, spices, soups, sauces, salads, protein products, etc. (12.0): | 0.10000 | 0.50000 |
| Foodstuffs intended for particular nutritional uses (13.0): | 0.20000 | 1.00000 |
| Non-alcoholic ("soft") beverages, excl. dairy products (14.1): | - | - |
| Alcoholic beverages, incl. alcohol-free and low-alcoholic counterparts (14.2): | 1.00000 | 5.00000 |
| Ready-to-eat savouries (15.0): | 1.00000 | 5.00000 |
| Composite foods (e.g. casseroles, meat pies, mincemeat) - foods that could not be placed in categories 01.0 - 15.0 (16.0): | 0.20000 | 1.00000 |
Safety References:
References:
Other Information:
Potential Blenders and core components note
Potential Uses:
Occurrence (nature, food, other): note
Synonyms:
| 1- | amino-2-methylethane | | 2- | amino-propaan | | 2- | amino-propane | | 2- | amino-propano | | 2- | aminopropane | | 1- | methyl ethyl amine | | 1- | methylethyl amine | | | propan-2-amine | | 2- | propanamine | | 2- | propane amine | | | propane, 2-amino- | | 2- | propaneamine | | 2- | propyl amine | | monoiso | propyl amine | | sec- | propyl amine | | 2- | propylamine | | iso | propylamine | | sec- | propylamine | | iso | propylamine natural 5% in ethyl alcohol |
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